ATE268768T1 - Antithrombosemittel - Google Patents
AntithrombosemittelInfo
- Publication number
- ATE268768T1 ATE268768T1 AT98920095T AT98920095T ATE268768T1 AT E268768 T1 ATE268768 T1 AT E268768T1 AT 98920095 T AT98920095 T AT 98920095T AT 98920095 T AT98920095 T AT 98920095T AT E268768 T1 ATE268768 T1 AT E268768T1
- Authority
- AT
- Austria
- Prior art keywords
- formula
- antithrombotic agents
- novel compounds
- compounds
- intermediates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4429697P | 1997-04-30 | 1997-04-30 | |
| PCT/US1998/008831 WO1998049160A1 (en) | 1997-04-30 | 1998-04-30 | Antithrombotic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE268768T1 true ATE268768T1 (de) | 2004-06-15 |
Family
ID=21931578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98920095T ATE268768T1 (de) | 1997-04-30 | 1998-04-30 | Antithrombosemittel |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6271227B1 (de) |
| EP (1) | EP0980366B1 (de) |
| JP (1) | JP2001522373A (de) |
| AT (1) | ATE268768T1 (de) |
| AU (1) | AU7274198A (de) |
| CA (1) | CA2287982A1 (de) |
| DE (1) | DE69824410T2 (de) |
| ES (1) | ES2223129T3 (de) |
| WO (1) | WO1998049160A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2306489A1 (en) * | 1997-10-03 | 1999-04-15 | Mark Gregory Stocksdale | Benzothiophenes |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3274213A (en) | 1961-09-05 | 1966-09-20 | Upjohn Co | Alkoxy-substituted 2-phenyl-1-(tertiary-aminoalkoxy)phenyl-3, 4-dihydronaphthalenes |
| US3293263A (en) | 1963-12-09 | 1966-12-20 | Upjohn Co | Diphenylbenzocycloalkenes |
| GB1456323A (en) | 1974-06-06 | 1976-11-24 | Labaz | Benzothiophenes process for preparing them and pharmaceutical compositions containing the same |
| US4001426A (en) | 1974-10-17 | 1977-01-04 | Smithkline Corporation | Substituted benzofurans and benzothiophenes |
| US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
| US4418068A (en) | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
| ZA928276B (en) | 1991-10-31 | 1993-05-06 | Daiichi Seiyaku Co | Aromatic amidine derivates and salts thereof. |
| JP3157882B2 (ja) | 1991-11-15 | 2001-04-16 | 帝国臓器製薬株式会社 | 新規なベンゾチオフエン誘導体 |
| US5482949A (en) | 1993-03-19 | 1996-01-09 | Eli Lilly And Company | Sulfonate derivatives of 3-aroylbenzo[b]thiophenes |
| US6756388B1 (en) | 1993-10-12 | 2004-06-29 | Pfizer Inc. | Benzothiophenes and related compounds as estrogen agonists |
| AU1440395A (en) | 1993-12-21 | 1995-07-10 | Eli Lilly And Company | Methods for the treatment or prevention of conditions associated with amyloidogenic reptides |
| EP0736007A4 (de) | 1993-12-21 | 1997-03-19 | Lilly Co Eli | Nicht-peptidische tachykinin rezeptor antagonisten |
| US5441965A (en) | 1993-12-21 | 1995-08-15 | Eli Lilly And Company | Methods of inhibiting thrombin |
| IL115582A0 (en) | 1994-10-14 | 1996-01-19 | Lilly Co Eli | Methods for treating resistant tumors |
| US5589482A (en) * | 1994-12-14 | 1996-12-31 | Pfizer Inc. | Benzo-thiophene estrogen agonists to treat prostatic hyperplasia |
| US5552401A (en) * | 1995-02-28 | 1996-09-03 | Eli Lilly And Company | 2-benzyl-3-arylbenzothiophenes |
| US5510357A (en) | 1995-02-28 | 1996-04-23 | Eli Lilly And Company | Benzothiophene compounds as anti-estrogenic agents |
| US5523309A (en) | 1995-03-10 | 1996-06-04 | Eli Lilly And Company | Benzofuran pharmaceutical compounds |
| US5567828A (en) | 1995-06-07 | 1996-10-22 | Eli Lilly And Company | Compounds and compositions with nitrogen-containing non-basic side |
| US5532254A (en) | 1995-06-07 | 1996-07-02 | Eli Lilly And Company | Modulation of calcium channels using benzothiophenes |
| JP2002500618A (ja) * | 1995-10-31 | 2002-01-08 | イーライ・リリー・アンド・カンパニー | 抗血栓性ジアミン |
-
1998
- 1998-04-30 US US09/423,124 patent/US6271227B1/en not_active Expired - Fee Related
- 1998-04-30 DE DE69824410T patent/DE69824410T2/de not_active Expired - Fee Related
- 1998-04-30 AU AU72741/98A patent/AU7274198A/en not_active Abandoned
- 1998-04-30 EP EP98920095A patent/EP0980366B1/de not_active Expired - Lifetime
- 1998-04-30 ES ES98920095T patent/ES2223129T3/es not_active Expired - Lifetime
- 1998-04-30 CA CA002287982A patent/CA2287982A1/en not_active Abandoned
- 1998-04-30 JP JP54742798A patent/JP2001522373A/ja active Pending
- 1998-04-30 AT AT98920095T patent/ATE268768T1/de not_active IP Right Cessation
- 1998-04-30 WO PCT/US1998/008831 patent/WO1998049160A1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| DE69824410T2 (de) | 2005-06-02 |
| JP2001522373A (ja) | 2001-11-13 |
| ES2223129T3 (es) | 2005-02-16 |
| EP0980366A1 (de) | 2000-02-23 |
| CA2287982A1 (en) | 1998-11-05 |
| WO1998049160A1 (en) | 1998-11-05 |
| AU7274198A (en) | 1998-11-24 |
| EP0980366B1 (de) | 2004-06-09 |
| US6271227B1 (en) | 2001-08-07 |
| DE69824410D1 (en) | 2004-07-15 |
| EP0980366A4 (de) | 2000-05-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |