LV12291A - Savienojums un farmaceitiskas kompozicijas ar triptazes aktivitates izmainam saistitu slimibu arstesanai - Google Patents
Savienojums un farmaceitiskas kompozicijas ar triptazes aktivitates izmainam saistitu slimibu arstesanaiInfo
- Publication number
- LV12291A LV12291A LV990027A LV990027A LV12291A LV 12291 A LV12291 A LV 12291A LV 990027 A LV990027 A LV 990027A LV 990027 A LV990027 A LV 990027A LV 12291 A LV12291 A LV 12291A
- Authority
- LV
- Latvia
- Prior art keywords
- triptase
- activity
- compound
- treatment
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
- C07D233/08—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms
- C07D233/12—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D233/14—Radicals substituted by oxygen atoms
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LVP-00-31A LV12459B (en) | 1996-07-30 | 2000-02-25 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF TRIPTASE ACTIVITY-RELATED DISEASES |
| LVP-00-30A LV12458B (en) | 1996-07-30 | 2000-02-25 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF TRIPTASE ACTIVITY-RELATED DISEASES |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2313996P | 1996-07-30 | 1996-07-30 | |
| US89577297A | 1997-07-17 | 1997-07-17 | |
| PCT/US1997/013422 WO1998004537A1 (en) | 1996-07-30 | 1997-07-30 | Novel compounds and compositions for treating diseases associated with tryptase activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| LV12291A true LV12291A (lv) | 1999-06-20 |
| LV12291B LV12291B (lv) | 2000-04-20 |
Family
ID=26696778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LVP-99-27A LV12291B (lv) | 1996-07-30 | 1999-02-18 | Savienojums un farmaceitiskās kompozīcijas ar triptāzes aktivitātes izmaiņām saistītu slimību ārstēšanai |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0934293A1 (lv) |
| JP (1) | JP2001509787A (lv) |
| KR (1) | KR20000029679A (lv) |
| CN (1) | CN1073103C (lv) |
| AU (1) | AU733621B2 (lv) |
| CA (1) | CA2262542A1 (lv) |
| CZ (1) | CZ29799A3 (lv) |
| EE (1) | EE9900036A (lv) |
| FI (1) | FI990171A (lv) |
| HU (1) | HUP0003267A3 (lv) |
| LV (1) | LV12291B (lv) |
| NO (1) | NO990433L (lv) |
| NZ (1) | NZ333713A (lv) |
| PL (1) | PL331465A1 (lv) |
| SI (1) | SI9720047A (lv) |
| SK (1) | SK8599A3 (lv) |
| WO (1) | WO1998004537A1 (lv) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6221914B1 (en) | 1997-11-10 | 2001-04-24 | Array Biopharma Inc. | Sulfonamide bridging compounds that inhibit tryptase activity |
| ES2233025T3 (es) * | 1998-02-06 | 2005-06-01 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Agente inhibidores de la triptasa. |
| JP2002502845A (ja) * | 1998-02-06 | 2002-01-29 | マックス−プランク−ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エー・ファオ | トリプターゼ阻害物質 |
| IL141654A0 (en) * | 1998-09-04 | 2002-03-10 | Byk Gulden Lomberg Chem Fab | Pyranose derivatives and pharmaceutical compositions containing the same |
| ATE279398T1 (de) * | 1999-08-10 | 2004-10-15 | Altana Pharma Ag | Diazocindionderivate und ihre verwendung als tryptase inhibitoren |
| JP2003509417A (ja) * | 1999-09-14 | 2003-03-11 | アルタナ ファルマ アクチエンゲゼルシャフト | トリプターゼインヒビター |
| AU1413301A (en) * | 1999-11-17 | 2001-05-30 | Sumitomo Pharmaceuticals Company, Limited | Diabetic remedy containing dipiperazine derivative |
| DE19955476A1 (de) * | 1999-11-18 | 2001-05-23 | Boehringer Ingelheim Pharma | Bis-basische Verbindungen als Tryptase-Inhibitoren, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
| US6815557B2 (en) | 1999-12-20 | 2004-11-09 | Altana Pharma Ag | Tryptase inhibitors |
| ES2222259T3 (es) * | 1999-12-20 | 2005-02-01 | Altana Pharma Ag | Inhibidores de triptasa. |
| PT1358182E (pt) | 2001-01-31 | 2004-12-31 | Altana Pharma Ag | Derivados de diazocinas e sua utilizacao como inibidores de triptase |
| DE60217076T2 (de) | 2001-02-21 | 2007-06-21 | Altana Pharma Ag | Tryptaseinhibitoren |
| EP1363874B1 (en) | 2001-02-21 | 2007-06-06 | ALTANA Pharma AG | Tryptase inhibitors |
| EP1370518A2 (en) * | 2001-03-15 | 2003-12-17 | ALTANA Pharma AG | Tryptase-inhibitors |
| WO2002074732A2 (en) * | 2001-03-15 | 2002-09-26 | Altana Pharma Ag | Tryptase-inhibitors |
| US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| HUP0400183A2 (hu) | 2001-06-11 | 2004-07-28 | Xenoport Inc. | Gaba-analóg prodrugok csökkentett toxicitású orális dózisformái |
| ATE348803T1 (de) | 2001-06-19 | 2007-01-15 | Altana Pharma Ag | Tryptase-inhibitoren |
| RU2440112C2 (ru) | 2004-11-04 | 2012-01-20 | Ксенопорт, Инк. | Пероральная дозированная форма габапентина замедленного высвобождения |
| US8399519B2 (en) * | 2008-12-19 | 2013-03-19 | Merz Pharma Gmbh & Co. Kgaa | 1-amino-alkylcyclohexane derivatives for the treatment of mast cell mediated diseases |
| TWI432188B (zh) | 2008-12-19 | 2014-04-01 | Merz Pharma Gmbh & Co Kgaa | 供治療發炎性皮膚疾病之１－胺基－烷基環己烷衍生物類 |
| FR3038605B1 (fr) | 2015-07-06 | 2018-08-24 | Universite Amiens Picardie Jules Verne | Diamines primaires vicinales associees a des motifs chelateurs de metaux et/ou de radicaux libres, actives contre les stress carbonyle et oxydant et leur utilisation |
| US20200199168A1 (en) * | 2017-05-12 | 2020-06-25 | Riken | Class a gpcr-binding compound modifier |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4845242A (en) * | 1987-04-28 | 1989-07-04 | Georgia Tech Research Corporation | Isocoumarins with basic substituents as serine proteases inhibitors, anticoagulants and anti-inflammatory agents |
| NZ263084A (en) * | 1993-03-12 | 1997-08-22 | Arris Pharm Corp | Dipeptide derivatives, treatment of immunomediated inflammatory disorders |
| SK282537B6 (sk) * | 1993-03-12 | 2002-10-08 | Axys Pharmaceuticals, Inc. | Inhibítor tryptázy alebo jeho farmaceuticky prijateľná soľ, farmaceutický prostriedok s jeho obsahom a jeho použitie |
| ATE189211T1 (de) * | 1994-06-01 | 2000-02-15 | Axys Pharm Inc | Zusammensetzungen und verfahren zur behandlung von durch mast-zellen verursachten krankheiten |
| NZ294392A (en) * | 1994-09-23 | 1999-05-28 | Axys Pharm Inc | Asthma drugs and compounds |
| CN1071751C (zh) * | 1995-03-24 | 2001-09-26 | 阿克西斯制药公司 | 可逆蛋白酶抑制剂 |
| TW438591B (en) * | 1995-06-07 | 2001-06-07 | Arris Pharm Corp | Reversible cysteine protease inhibitors |
-
1997
- 1997-07-30 SK SK85-99A patent/SK8599A3/sk unknown
- 1997-07-30 CN CN97196877A patent/CN1073103C/zh not_active Expired - Fee Related
- 1997-07-30 EP EP97937066A patent/EP0934293A1/en not_active Withdrawn
- 1997-07-30 KR KR1019997000757A patent/KR20000029679A/ko not_active Application Discontinuation
- 1997-07-30 CZ CZ99297A patent/CZ29799A3/cs unknown
- 1997-07-30 JP JP50913698A patent/JP2001509787A/ja active Pending
- 1997-07-30 AU AU39670/97A patent/AU733621B2/en not_active Ceased
- 1997-07-30 PL PL97331465A patent/PL331465A1/xx unknown
- 1997-07-30 NZ NZ333713A patent/NZ333713A/xx unknown
- 1997-07-30 EE EEP199900036A patent/EE9900036A/xx unknown
- 1997-07-30 CA CA002262542A patent/CA2262542A1/en not_active Abandoned
- 1997-07-30 HU HU0003267A patent/HUP0003267A3/hu unknown
- 1997-07-30 SI SI9720047A patent/SI9720047A/sl unknown
- 1997-07-30 WO PCT/US1997/013422 patent/WO1998004537A1/en not_active Application Discontinuation
-
1999
- 1999-01-29 FI FI990171A patent/FI990171A/fi unknown
- 1999-01-29 NO NO990433A patent/NO990433L/no not_active Application Discontinuation
- 1999-02-18 LV LVP-99-27A patent/LV12291B/lv unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI9720047A (sl) | 1999-08-31 |
| NO990433L (no) | 1999-03-25 |
| JP2001509787A (ja) | 2001-07-24 |
| PL331465A1 (en) | 1999-07-19 |
| CZ29799A3 (cs) | 1999-06-16 |
| FI990171A (fi) | 1999-03-23 |
| NO990433D0 (no) | 1999-01-29 |
| LV12291B (lv) | 2000-04-20 |
| CN1073103C (zh) | 2001-10-17 |
| HUP0003267A2 (hu) | 2001-06-28 |
| FI990171A0 (fi) | 1999-01-29 |
| EE9900036A (et) | 1999-08-16 |
| HUP0003267A3 (en) | 2002-02-28 |
| NZ333713A (en) | 2000-12-22 |
| SK8599A3 (en) | 2000-03-13 |
| KR20000029679A (ko) | 2000-05-25 |
| CA2262542A1 (en) | 1998-02-05 |
| WO1998004537A1 (en) | 1998-02-05 |
| CN1226892A (zh) | 1999-08-25 |
| AU733621B2 (en) | 2001-05-17 |
| EP0934293A1 (en) | 1999-08-11 |
| AU3967097A (en) | 1998-02-20 |
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