ATE287397T1 - Chinoline derivate und ihre anwendung als antitumor agentien - Google Patents
Chinoline derivate und ihre anwendung als antitumor agentienInfo
- Publication number
- ATE287397T1 ATE287397T1 AT02752656T AT02752656T ATE287397T1 AT E287397 T1 ATE287397 T1 AT E287397T1 AT 02752656 T AT02752656 T AT 02752656T AT 02752656 T AT02752656 T AT 02752656T AT E287397 T1 ATE287397 T1 AT E287397T1
- Authority
- AT
- Austria
- Prior art keywords
- formula
- compound
- antitumor agents
- salt
- chinoline derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30914401P | 2001-07-31 | 2001-07-31 | |
| PCT/US2002/024442 WO2003011832A1 (en) | 2001-07-31 | 2002-07-31 | Quinoline derivatives and use thereof as antitumor agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE287397T1 true ATE287397T1 (de) | 2005-02-15 |
Family
ID=23196886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02752656T ATE287397T1 (de) | 2001-07-31 | 2002-07-31 | Chinoline derivate und ihre anwendung als antitumor agentien |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US6867219B2 (de) |
| EP (1) | EP1412332B1 (de) |
| JP (1) | JP4310185B2 (de) |
| KR (1) | KR20040055774A (de) |
| AT (1) | ATE287397T1 (de) |
| AU (1) | AU2002355747B2 (de) |
| CA (1) | CA2456173A1 (de) |
| DE (1) | DE60202682T2 (de) |
| DK (1) | DK1412332T3 (de) |
| EA (1) | EA007205B1 (de) |
| ES (1) | ES2236548T3 (de) |
| GE (1) | GEP20063754B (de) |
| HU (1) | HUP0401562A2 (de) |
| IL (2) | IL160082A0 (de) |
| MX (1) | MXPA04000968A (de) |
| NO (1) | NO326463B1 (de) |
| NZ (1) | NZ530806A (de) |
| PL (1) | PL367340A1 (de) |
| PT (1) | PT1412332E (de) |
| UA (1) | UA75691C2 (de) |
| WO (1) | WO2003011832A1 (de) |
| ZA (1) | ZA200401185B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2254385T3 (es) * | 2000-02-29 | 2006-06-16 | Millennium Pharmaceuticals, Inc. | Benzamidas e inhibidores relacionados del factor xa. |
| EA007205B1 (ru) * | 2001-07-31 | 2006-08-25 | Вейне Стейт Юниверсити | Производные хинолина и их использование в качестве противоопухолевых средств |
| UA79293C2 (en) * | 2002-07-03 | 2007-06-11 | Univ Wayne State | 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents |
| BR0313789A (pt) * | 2002-08-24 | 2005-07-05 | Zentaris Gmbh | Medicamento contendo disorazóis e seus derivados para o tratamento de doenças tumorais malignas e benignas |
| US20070054938A1 (en) * | 2005-09-07 | 2007-03-08 | Horwitz Jerome P | Antitumor agents |
| US8183379B2 (en) | 2005-09-07 | 2012-05-22 | Wayne State University | Antitumor agents |
| US7470788B2 (en) | 2005-09-07 | 2008-12-30 | Wayne State University | Antitumor agents |
| EP1897542A1 (de) * | 2006-09-07 | 2008-03-12 | Sanofi-Aventis | Wässrige Formulierung enthaltend einen antitumoralen Wirkstoff |
| JO2685B1 (en) * | 2006-12-06 | 2013-03-03 | جانسين فارماسوتيكا ان في | Quinoline antibacterial derivatives |
| WO2009002955A1 (en) * | 2007-06-27 | 2008-12-31 | Sanofi-Aventis U.S. Llc | Process for the preparation of (2r)-2-[4-(7-bromo-2-quinolyloxy)phenoxy]propanoic acid |
| CA2838387A1 (en) | 2011-06-06 | 2012-12-13 | Chevron Phillips Chemical Company Lp | Use of metallocene compounds for cancer treatment |
| WO2024132001A1 (en) * | 2022-12-21 | 2024-06-27 | Charles University, Faculty Of Pharmacy In Hradec Kralove | Multitarget nuclear receptor ligands based on 2-(4-(quinolin-2-yloxy)phenoxy)propanoic acid and 2-(4-(quinoxalin-2-yloxy)phenoxy)propanoic acid for the treatment of metabolic and liver diseases |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6033389B2 (ja) | 1979-02-22 | 1985-08-02 | 日産化学工業株式会社 | 複素環エ−テル系フェノシキ脂肪酸誘導体、その製造法および該誘導体を含有する除草剤 |
| US5364831A (en) | 1980-08-06 | 1994-11-15 | Nissan Chemical Industries Ltd. | Quinoxaline derivatives and herbicidal composition |
| US6197728B1 (en) | 1980-08-06 | 2001-03-06 | Nissan Chemical Industries Ltd. | Quinoxaline derivatives and herbicidal composition |
| US5250690A (en) * | 1985-05-02 | 1993-10-05 | Dowelanco | Haloalkoxy anilide derivatives of 2-4(-heterocyclic oxyphenoxy)alkanoic or alkenoic acids and their use as herbicides |
| EA007205B1 (ru) | 2001-07-31 | 2006-08-25 | Вейне Стейт Юниверсити | Производные хинолина и их использование в качестве противоопухолевых средств |
| UA79293C2 (en) * | 2002-07-03 | 2007-06-11 | Univ Wayne State | 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents |
| US7470788B2 (en) * | 2005-09-07 | 2008-12-30 | Wayne State University | Antitumor agents |
-
2002
- 2002-07-31 EA EA200400219A patent/EA007205B1/ru not_active IP Right Cessation
- 2002-07-31 EP EP02752656A patent/EP1412332B1/de not_active Expired - Lifetime
- 2002-07-31 AT AT02752656T patent/ATE287397T1/de not_active IP Right Cessation
- 2002-07-31 AU AU2002355747A patent/AU2002355747B2/en not_active Ceased
- 2002-07-31 IL IL16008202A patent/IL160082A0/xx unknown
- 2002-07-31 JP JP2003517024A patent/JP4310185B2/ja not_active Expired - Fee Related
- 2002-07-31 KR KR10-2004-7001559A patent/KR20040055774A/ko not_active Abandoned
- 2002-07-31 CA CA002456173A patent/CA2456173A1/en not_active Abandoned
- 2002-07-31 NZ NZ530806A patent/NZ530806A/en unknown
- 2002-07-31 HU HU0401562A patent/HUP0401562A2/hu unknown
- 2002-07-31 PT PT02752656T patent/PT1412332E/pt unknown
- 2002-07-31 PL PL02367340A patent/PL367340A1/xx not_active Application Discontinuation
- 2002-07-31 DK DK02752656T patent/DK1412332T3/da active
- 2002-07-31 GE GE5486A patent/GEP20063754B/en unknown
- 2002-07-31 MX MXPA04000968A patent/MXPA04000968A/es active IP Right Grant
- 2002-07-31 DE DE60202682T patent/DE60202682T2/de not_active Expired - Lifetime
- 2002-07-31 WO PCT/US2002/024442 patent/WO2003011832A1/en not_active Ceased
- 2002-07-31 ES ES02752656T patent/ES2236548T3/es not_active Expired - Lifetime
- 2002-07-31 UA UA2004021374A patent/UA75691C2/uk unknown
- 2002-07-31 US US10/210,781 patent/US6867219B2/en not_active Expired - Lifetime
-
2004
- 2004-01-27 IL IL160082A patent/IL160082A/en not_active IP Right Cessation
- 2004-01-28 NO NO20040382A patent/NO326463B1/no not_active IP Right Cessation
- 2004-02-13 ZA ZA200401185A patent/ZA200401185B/en unknown
- 2004-12-10 US US11/009,457 patent/US7241894B2/en not_active Expired - Fee Related
-
2007
- 2007-05-24 US US11/753,197 patent/US7507749B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0401562A2 (hu) | 2004-12-28 |
| DE60202682D1 (de) | 2005-02-24 |
| NZ530806A (en) | 2006-05-26 |
| UA75691C2 (en) | 2006-05-15 |
| US20050159447A1 (en) | 2005-07-21 |
| NO20040382L (no) | 2004-03-26 |
| EA007205B1 (ru) | 2006-08-25 |
| JP2004538314A (ja) | 2004-12-24 |
| US6867219B2 (en) | 2005-03-15 |
| IL160082A0 (en) | 2004-06-20 |
| US20070232643A1 (en) | 2007-10-04 |
| GEP20063754B (en) | 2006-02-27 |
| US20030144321A1 (en) | 2003-07-31 |
| JP4310185B2 (ja) | 2009-08-05 |
| MXPA04000968A (es) | 2005-02-17 |
| US7241894B2 (en) | 2007-07-10 |
| PL367340A1 (en) | 2005-02-21 |
| CA2456173A1 (en) | 2003-02-13 |
| AU2002355747B2 (en) | 2007-12-20 |
| WO2003011832A1 (en) | 2003-02-13 |
| EP1412332A1 (de) | 2004-04-28 |
| DE60202682T2 (de) | 2005-12-29 |
| EP1412332B1 (de) | 2005-01-19 |
| KR20040055774A (ko) | 2004-06-26 |
| NO326463B1 (no) | 2008-12-08 |
| PT1412332E (pt) | 2005-06-30 |
| US7507749B2 (en) | 2009-03-24 |
| DK1412332T3 (da) | 2005-05-30 |
| EA200400219A1 (ru) | 2004-12-30 |
| ES2236548T3 (es) | 2005-07-16 |
| IL160082A (en) | 2009-06-15 |
| ZA200401185B (en) | 2004-10-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1412332 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |