PT1412332E - Derivados de quinolina e sua utilizacao como agentes antitumorais - Google Patents
Derivados de quinolina e sua utilizacao como agentes antitumoraisInfo
- Publication number
- PT1412332E PT1412332E PT02752656T PT02752656T PT1412332E PT 1412332 E PT1412332 E PT 1412332E PT 02752656 T PT02752656 T PT 02752656T PT 02752656 T PT02752656 T PT 02752656T PT 1412332 E PT1412332 E PT 1412332E
- Authority
- PT
- Portugal
- Prior art keywords
- formula
- compound
- antitumor agents
- quinoline derivatives
- salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30914401P | 2001-07-31 | 2001-07-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1412332E true PT1412332E (pt) | 2005-06-30 |
Family
ID=23196886
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT02752656T PT1412332E (pt) | 2001-07-31 | 2002-07-31 | Derivados de quinolina e sua utilizacao como agentes antitumorais |
Country Status (22)
Country | Link |
---|---|
US (3) | US6867219B2 (pt) |
EP (1) | EP1412332B1 (pt) |
JP (1) | JP4310185B2 (pt) |
KR (1) | KR20040055774A (pt) |
AT (1) | ATE287397T1 (pt) |
AU (1) | AU2002355747B2 (pt) |
CA (1) | CA2456173A1 (pt) |
DE (1) | DE60202682T2 (pt) |
DK (1) | DK1412332T3 (pt) |
EA (1) | EA007205B1 (pt) |
ES (1) | ES2236548T3 (pt) |
GE (1) | GEP20063754B (pt) |
HU (1) | HUP0401562A2 (pt) |
IL (2) | IL160082A0 (pt) |
MX (1) | MXPA04000968A (pt) |
NO (1) | NO326463B1 (pt) |
NZ (1) | NZ530806A (pt) |
PL (1) | PL367340A1 (pt) |
PT (1) | PT1412332E (pt) |
UA (1) | UA75691C2 (pt) |
WO (1) | WO2003011832A1 (pt) |
ZA (1) | ZA200401185B (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001064642A2 (en) * | 2000-02-29 | 2001-09-07 | Cor Therapeutics, Inc. | Benzamides and related inhibitors of factor xa |
DK1412332T3 (da) * | 2001-07-31 | 2005-05-30 | Univ Wayne State | Quinolinderivater og anvendelse deraf som antitumormidler |
UA79293C2 (en) * | 2002-07-03 | 2007-06-11 | Univ Wayne State | 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents |
RU2322236C2 (ru) * | 2002-08-24 | 2008-04-20 | Центарис Гмбх | Лекарственное средство для лечения доброкачественных и злокачественных опухолевых заболеваний, содержащее производное дисоразола |
US7470788B2 (en) * | 2005-09-07 | 2008-12-30 | Wayne State University | Antitumor agents |
US20070054938A1 (en) * | 2005-09-07 | 2007-03-08 | Horwitz Jerome P | Antitumor agents |
US8183379B2 (en) | 2005-09-07 | 2012-05-22 | Wayne State University | Antitumor agents |
EP1897542A1 (en) * | 2006-09-07 | 2008-03-12 | Sanofi-Aventis | Aqueous formulation comprising an antitumor agent |
JO2685B1 (en) * | 2006-12-06 | 2013-03-03 | جانسين فارماسوتيكا ان في | Quinoline antibacterial derivatives |
WO2009002955A1 (en) * | 2007-06-27 | 2008-12-31 | Sanofi-Aventis U.S. Llc | Process for the preparation of (2r)-2-[4-(7-bromo-2-quinolyloxy)phenoxy]propanoic acid |
JP2014516075A (ja) | 2011-06-06 | 2014-07-07 | シェブロン フィリップス ケミカル カンパニー エルピー | 癌治療のためのメタロセン化合物の使用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6033389B2 (ja) * | 1979-02-22 | 1985-08-02 | 日産化学工業株式会社 | 複素環エ−テル系フェノシキ脂肪酸誘導体、その製造法および該誘導体を含有する除草剤 |
US6197728B1 (en) * | 1980-08-06 | 2001-03-06 | Nissan Chemical Industries Ltd. | Quinoxaline derivatives and herbicidal composition |
US5364831A (en) * | 1980-08-06 | 1994-11-15 | Nissan Chemical Industries Ltd. | Quinoxaline derivatives and herbicidal composition |
US5250690A (en) * | 1985-05-02 | 1993-10-05 | Dowelanco | Haloalkoxy anilide derivatives of 2-4(-heterocyclic oxyphenoxy)alkanoic or alkenoic acids and their use as herbicides |
DK1412332T3 (da) * | 2001-07-31 | 2005-05-30 | Univ Wayne State | Quinolinderivater og anvendelse deraf som antitumormidler |
UA79293C2 (en) * | 2002-07-03 | 2007-06-11 | Univ Wayne State | 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents |
US7470788B2 (en) * | 2005-09-07 | 2008-12-30 | Wayne State University | Antitumor agents |
-
2002
- 2002-07-31 DK DK02752656T patent/DK1412332T3/da active
- 2002-07-31 EA EA200400219A patent/EA007205B1/ru not_active IP Right Cessation
- 2002-07-31 KR KR10-2004-7001559A patent/KR20040055774A/ko active IP Right Grant
- 2002-07-31 HU HU0401562A patent/HUP0401562A2/hu unknown
- 2002-07-31 UA UA2004021374A patent/UA75691C2/uk unknown
- 2002-07-31 WO PCT/US2002/024442 patent/WO2003011832A1/en active IP Right Grant
- 2002-07-31 PT PT02752656T patent/PT1412332E/pt unknown
- 2002-07-31 AU AU2002355747A patent/AU2002355747B2/en not_active Ceased
- 2002-07-31 DE DE60202682T patent/DE60202682T2/de not_active Expired - Lifetime
- 2002-07-31 JP JP2003517024A patent/JP4310185B2/ja not_active Expired - Fee Related
- 2002-07-31 ES ES02752656T patent/ES2236548T3/es not_active Expired - Lifetime
- 2002-07-31 MX MXPA04000968A patent/MXPA04000968A/es active IP Right Grant
- 2002-07-31 EP EP02752656A patent/EP1412332B1/en not_active Expired - Lifetime
- 2002-07-31 CA CA002456173A patent/CA2456173A1/en not_active Abandoned
- 2002-07-31 PL PL02367340A patent/PL367340A1/xx not_active Application Discontinuation
- 2002-07-31 AT AT02752656T patent/ATE287397T1/de not_active IP Right Cessation
- 2002-07-31 US US10/210,781 patent/US6867219B2/en not_active Expired - Lifetime
- 2002-07-31 GE GE5486A patent/GEP20063754B/en unknown
- 2002-07-31 IL IL16008202A patent/IL160082A0/xx unknown
- 2002-07-31 NZ NZ530806A patent/NZ530806A/en unknown
-
2004
- 2004-01-27 IL IL160082A patent/IL160082A/en not_active IP Right Cessation
- 2004-01-28 NO NO20040382A patent/NO326463B1/no not_active IP Right Cessation
- 2004-02-13 ZA ZA200401185A patent/ZA200401185B/en unknown
- 2004-12-10 US US11/009,457 patent/US7241894B2/en not_active Expired - Fee Related
-
2007
- 2007-05-24 US US11/753,197 patent/US7507749B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US7507749B2 (en) | 2009-03-24 |
HUP0401562A2 (hu) | 2004-12-28 |
IL160082A (en) | 2009-06-15 |
GEP20063754B (en) | 2006-02-27 |
EP1412332A1 (en) | 2004-04-28 |
JP4310185B2 (ja) | 2009-08-05 |
AU2002355747B2 (en) | 2007-12-20 |
NZ530806A (en) | 2006-05-26 |
UA75691C2 (en) | 2006-05-15 |
EP1412332B1 (en) | 2005-01-19 |
ZA200401185B (en) | 2004-10-21 |
ES2236548T3 (es) | 2005-07-16 |
ATE287397T1 (de) | 2005-02-15 |
US20030144321A1 (en) | 2003-07-31 |
US6867219B2 (en) | 2005-03-15 |
NO326463B1 (no) | 2008-12-08 |
DE60202682T2 (de) | 2005-12-29 |
WO2003011832A1 (en) | 2003-02-13 |
JP2004538314A (ja) | 2004-12-24 |
MXPA04000968A (es) | 2005-02-17 |
KR20040055774A (ko) | 2004-06-26 |
NO20040382L (no) | 2004-03-26 |
EA200400219A1 (ru) | 2004-12-30 |
DK1412332T3 (da) | 2005-05-30 |
IL160082A0 (en) | 2004-06-20 |
DE60202682D1 (de) | 2005-02-24 |
EA007205B1 (ru) | 2006-08-25 |
CA2456173A1 (en) | 2003-02-13 |
US20070232643A1 (en) | 2007-10-04 |
PL367340A1 (en) | 2005-02-21 |
US7241894B2 (en) | 2007-07-10 |
US20050159447A1 (en) | 2005-07-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE264852T1 (de) | Chinolinderivate als antibakterielle mittel | |
ECSP066314A (es) | Derivados piridilo y su uso como agentes terapéuticos | |
BG66085B1 (bg) | Фенилаланинови производни | |
NO20044731L (no) | Kinolin- og isokinolinderivater fremgangsmate for fremstilling derav og anvendelse derav som betennelseshemmere | |
ATE307810T1 (de) | Imidazol-2-carbonsäureamid derivate als raf- kinase-inhibitoren | |
EP1248612A4 (en) | NEW SUBSTANCES AND COMPOUNDS AS PROTEASE INHIBITORS | |
DK1539700T3 (da) | 8-hydroxyquinolin-derivater | |
MXPA03005464A (es) | Agentes antivirales. | |
EA200700099A1 (ru) | Производные пиридина | |
BRPI0418939A (pt) | derivados de nicotinamida e sua utilização como agentes terapêuticos | |
BR0108816A (pt) | Derivados de quinolina como antagonistas alfa-2 | |
SE0100569D0 (sv) | New compounds | |
BRPI0409959A (pt) | uso de derivados de azetidinacarboxamida em terapia | |
PT1412332E (pt) | Derivados de quinolina e sua utilizacao como agentes antitumorais | |
SE0102440D0 (sv) | New compound | |
SG145570A1 (en) | 4-æ7-halo-2-quino(xa-)linyloxy!phenoxy-propionic acid derivatives as antineoplastic agents | |
SE0401655D0 (sv) | New compounds | |
ATE424200T1 (de) | Solubilisierte topoisomerase-gift-mittel | |
ATE390923T1 (de) | Topoisomerase-giftmittel | |
ATE308540T1 (de) | Antithrombosemittel | |
TNSN08093A1 (en) | Quinoline derivatives and use as antitumor agents | |
EE200200660A (et) | Akrüloüüldistamütsiini derivaati sisaldav farmatseutiline kompositsioon, derivaadi kasutamine tuumorivastase ravimi valmistamiseks ning kombineeritudravimpreparaat | |
SE9900190D0 (sv) | New compounds | |
EA200600022A1 (ru) | Применение производных бицикло [2.2.1] гептана для приготовления нейропротекторных фармацевтических композиций | |
TW200744596A (en) | Antitumor agents |