PL367340A1 - Quinoline derivatives and use thereof as antitumor agents - Google Patents
Quinoline derivatives and use thereof as antitumor agentsInfo
- Publication number
- PL367340A1 PL367340A1 PL02367340A PL36734002A PL367340A1 PL 367340 A1 PL367340 A1 PL 367340A1 PL 02367340 A PL02367340 A PL 02367340A PL 36734002 A PL36734002 A PL 36734002A PL 367340 A1 PL367340 A1 PL 367340A1
- Authority
- PL
- Poland
- Prior art keywords
- formula
- compound
- antitumor agents
- quinoline derivatives
- salt
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title abstract 2
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 title 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 150000003839 salts Chemical class 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30914401P | 2001-07-31 | 2001-07-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL367340A1 true PL367340A1 (en) | 2005-02-21 |
Family
ID=23196886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL02367340A PL367340A1 (en) | 2001-07-31 | 2002-07-31 | Quinoline derivatives and use thereof as antitumor agents |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US6867219B2 (enExample) |
| EP (1) | EP1412332B1 (enExample) |
| JP (1) | JP4310185B2 (enExample) |
| KR (1) | KR20040055774A (enExample) |
| AT (1) | ATE287397T1 (enExample) |
| AU (1) | AU2002355747B2 (enExample) |
| CA (1) | CA2456173A1 (enExample) |
| DE (1) | DE60202682T2 (enExample) |
| DK (1) | DK1412332T3 (enExample) |
| EA (1) | EA007205B1 (enExample) |
| ES (1) | ES2236548T3 (enExample) |
| GE (1) | GEP20063754B (enExample) |
| HU (1) | HUP0401562A2 (enExample) |
| IL (2) | IL160082A0 (enExample) |
| MX (1) | MXPA04000968A (enExample) |
| NO (1) | NO326463B1 (enExample) |
| NZ (1) | NZ530806A (enExample) |
| PL (1) | PL367340A1 (enExample) |
| PT (1) | PT1412332E (enExample) |
| UA (1) | UA75691C2 (enExample) |
| WO (1) | WO2003011832A1 (enExample) |
| ZA (1) | ZA200401185B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001245353A1 (en) * | 2000-02-29 | 2001-09-12 | Cor Therapeutics, Inc. | Benzamides and related inhibitors of factor xa |
| PL367340A1 (en) * | 2001-07-31 | 2005-02-21 | Wayne State University | Quinoline derivatives and use thereof as antitumor agents |
| UA79293C2 (en) * | 2002-07-03 | 2007-06-11 | Univ Wayne State | 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents |
| WO2004024149A1 (de) * | 2002-08-24 | 2004-03-25 | Zentaris Gmbh | Arzneimittel enthaltend disorale und ihre derivate und deren anwendung zur behandlung gutartiger und bosärtiger tumorerkrankungen |
| US20070054938A1 (en) * | 2005-09-07 | 2007-03-08 | Horwitz Jerome P | Antitumor agents |
| US7470788B2 (en) * | 2005-09-07 | 2008-12-30 | Wayne State University | Antitumor agents |
| US8183379B2 (en) * | 2005-09-07 | 2012-05-22 | Wayne State University | Antitumor agents |
| EP1897542A1 (en) * | 2006-09-07 | 2008-03-12 | Sanofi-Aventis | Aqueous formulation comprising an antitumor agent |
| JO2685B1 (en) * | 2006-12-06 | 2013-03-03 | جانسين فارماسوتيكا ان في | Quinoline antibacterial derivatives |
| WO2009002955A1 (en) * | 2007-06-27 | 2008-12-31 | Sanofi-Aventis U.S. Llc | Process for the preparation of (2r)-2-[4-(7-bromo-2-quinolyloxy)phenoxy]propanoic acid |
| US8809562B2 (en) | 2011-06-06 | 2014-08-19 | Chevron Phillips Chemical Company Lp | Use of metallocene compounds for cancer treatment |
| WO2024132001A1 (en) * | 2022-12-21 | 2024-06-27 | Charles University, Faculty Of Pharmacy In Hradec Kralove | Multitarget nuclear receptor ligands based on 2-(4-(quinolin-2-yloxy)phenoxy)propanoic acid and 2-(4-(quinoxalin-2-yloxy)phenoxy)propanoic acid for the treatment of metabolic and liver diseases |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6033389B2 (ja) | 1979-02-22 | 1985-08-02 | 日産化学工業株式会社 | 複素環エ−テル系フェノシキ脂肪酸誘導体、その製造法および該誘導体を含有する除草剤 |
| US5364831A (en) | 1980-08-06 | 1994-11-15 | Nissan Chemical Industries Ltd. | Quinoxaline derivatives and herbicidal composition |
| US6197728B1 (en) | 1980-08-06 | 2001-03-06 | Nissan Chemical Industries Ltd. | Quinoxaline derivatives and herbicidal composition |
| US5250690A (en) * | 1985-05-02 | 1993-10-05 | Dowelanco | Haloalkoxy anilide derivatives of 2-4(-heterocyclic oxyphenoxy)alkanoic or alkenoic acids and their use as herbicides |
| PL367340A1 (en) * | 2001-07-31 | 2005-02-21 | Wayne State University | Quinoline derivatives and use thereof as antitumor agents |
| UA79293C2 (en) * | 2002-07-03 | 2007-06-11 | Univ Wayne State | 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents |
| US7470788B2 (en) * | 2005-09-07 | 2008-12-30 | Wayne State University | Antitumor agents |
-
2002
- 2002-07-31 PL PL02367340A patent/PL367340A1/xx not_active Application Discontinuation
- 2002-07-31 ES ES02752656T patent/ES2236548T3/es not_active Expired - Lifetime
- 2002-07-31 DE DE60202682T patent/DE60202682T2/de not_active Expired - Lifetime
- 2002-07-31 DK DK02752656T patent/DK1412332T3/da active
- 2002-07-31 MX MXPA04000968A patent/MXPA04000968A/es active IP Right Grant
- 2002-07-31 AT AT02752656T patent/ATE287397T1/de not_active IP Right Cessation
- 2002-07-31 HU HU0401562A patent/HUP0401562A2/hu unknown
- 2002-07-31 UA UA2004021374A patent/UA75691C2/uk unknown
- 2002-07-31 KR KR10-2004-7001559A patent/KR20040055774A/ko not_active Abandoned
- 2002-07-31 JP JP2003517024A patent/JP4310185B2/ja not_active Expired - Fee Related
- 2002-07-31 AU AU2002355747A patent/AU2002355747B2/en not_active Ceased
- 2002-07-31 GE GE5486A patent/GEP20063754B/en unknown
- 2002-07-31 EA EA200400219A patent/EA007205B1/ru not_active IP Right Cessation
- 2002-07-31 NZ NZ530806A patent/NZ530806A/en unknown
- 2002-07-31 CA CA002456173A patent/CA2456173A1/en not_active Abandoned
- 2002-07-31 WO PCT/US2002/024442 patent/WO2003011832A1/en not_active Ceased
- 2002-07-31 IL IL16008202A patent/IL160082A0/xx unknown
- 2002-07-31 EP EP02752656A patent/EP1412332B1/en not_active Expired - Lifetime
- 2002-07-31 PT PT02752656T patent/PT1412332E/pt unknown
- 2002-07-31 US US10/210,781 patent/US6867219B2/en not_active Expired - Lifetime
-
2004
- 2004-01-27 IL IL160082A patent/IL160082A/en not_active IP Right Cessation
- 2004-01-28 NO NO20040382A patent/NO326463B1/no not_active IP Right Cessation
- 2004-02-13 ZA ZA200401185A patent/ZA200401185B/en unknown
- 2004-12-10 US US11/009,457 patent/US7241894B2/en not_active Expired - Fee Related
-
2007
- 2007-05-24 US US11/753,197 patent/US7507749B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0401562A2 (hu) | 2004-12-28 |
| NZ530806A (en) | 2006-05-26 |
| UA75691C2 (en) | 2006-05-15 |
| US7507749B2 (en) | 2009-03-24 |
| NO326463B1 (no) | 2008-12-08 |
| IL160082A (en) | 2009-06-15 |
| EA200400219A1 (ru) | 2004-12-30 |
| DK1412332T3 (da) | 2005-05-30 |
| EP1412332A1 (en) | 2004-04-28 |
| AU2002355747B2 (en) | 2007-12-20 |
| JP2004538314A (ja) | 2004-12-24 |
| IL160082A0 (en) | 2004-06-20 |
| ZA200401185B (en) | 2004-10-21 |
| US20070232643A1 (en) | 2007-10-04 |
| US20050159447A1 (en) | 2005-07-21 |
| CA2456173A1 (en) | 2003-02-13 |
| EA007205B1 (ru) | 2006-08-25 |
| US20030144321A1 (en) | 2003-07-31 |
| KR20040055774A (ko) | 2004-06-26 |
| JP4310185B2 (ja) | 2009-08-05 |
| GEP20063754B (en) | 2006-02-27 |
| NO20040382L (no) | 2004-03-26 |
| US7241894B2 (en) | 2007-07-10 |
| PT1412332E (pt) | 2005-06-30 |
| DE60202682T2 (de) | 2005-12-29 |
| ES2236548T3 (es) | 2005-07-16 |
| DE60202682D1 (de) | 2005-02-24 |
| EP1412332B1 (en) | 2005-01-19 |
| US6867219B2 (en) | 2005-03-15 |
| ATE287397T1 (de) | 2005-02-15 |
| WO2003011832A1 (en) | 2003-02-13 |
| MXPA04000968A (es) | 2005-02-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |