DE602004010889T2 - Sulfonamid-derivate als ppar-modulatoren - Google Patents

Sulfonamid-derivate als ppar-modulatoren Download PDF

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DE602004010889T2
DE602004010889T2 DE602004010889T DE602004010889T DE602004010889T2 DE 602004010889 T2 DE602004010889 T2 DE 602004010889T2 DE 602004010889 T DE602004010889 T DE 602004010889T DE 602004010889 T DE602004010889 T DE 602004010889T DE 602004010889 T2 DE602004010889 T2 DE 602004010889T2
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alkyl
aryl
hydrogen
heteroaryl
alkoxy
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DE602004010889D1 (de
Inventor
Scott Eugene Indianapolis CONNER
Lynn Stacy Indianapolis GOSSETT
Jonathan Edward Avon GREEN
Winton Dennis Jr. Carmel JONES
Nathan Bryan Brownsburg MANTLO
Donald Paul Indianapolis MATTHEWS
Daniel Ray Carmel MAYHUGH
Daryl Lynn Fishers SMITH
Jennifer Ann San Jose VANCE
Xiaodong Carmel WANG
Alan M Carmel WARSHAWSKY
Leonard Larry Jr. Greenwood WINNEROSKI
Yanping Fishers XU
Guoxin Noblesville ZHU
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Eli Lilly and Co
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Eli Lilly and Co
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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
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    • C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
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    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
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JP2006520755A (ja) 2006-09-14
US7655641B2 (en) 2010-02-02
ES2297382T3 (es) 2008-05-01
US20060217433A1 (en) 2006-09-28
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MXPA05008581A (es) 2005-11-04
EP1597248A2 (en) 2005-11-23
EP1597248B1 (en) 2007-12-26
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CA2512883A1 (en) 2004-09-02
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