CN1751037A - 作为ppar调节剂的磺酰胺衍生物 - Google Patents
作为ppar调节剂的磺酰胺衍生物 Download PDFInfo
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- CN1751037A CN1751037A CNA2004800042507A CN200480004250A CN1751037A CN 1751037 A CN1751037 A CN 1751037A CN A2004800042507 A CNA2004800042507 A CN A2004800042507A CN 200480004250 A CN200480004250 A CN 200480004250A CN 1751037 A CN1751037 A CN 1751037A
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- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
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- C07C2601/14—The ring being saturated
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44830703P | 2003-02-14 | 2003-02-14 | |
| US60/448,307 | 2003-02-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1751037A true CN1751037A (zh) | 2006-03-22 |
Family
ID=32908574
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CNA2004800042507A Pending CN1751037A (zh) | 2003-02-14 | 2004-02-10 | 作为ppar调节剂的磺酰胺衍生物 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7655641B2 (https=) |
| EP (1) | EP1597248B1 (https=) |
| JP (1) | JP2006520755A (https=) |
| CN (1) | CN1751037A (https=) |
| AT (1) | ATE382043T1 (https=) |
| AU (1) | AU2004212887A1 (https=) |
| BR (1) | BRPI0407180A (https=) |
| CA (1) | CA2512883A1 (https=) |
| DE (1) | DE602004010889T2 (https=) |
| ES (1) | ES2297382T3 (https=) |
| MX (1) | MXPA05008581A (https=) |
| WO (1) | WO2004073606A2 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102336689A (zh) * | 2011-08-29 | 2012-02-01 | 天津市筠凯化工科技有限公司 | 4-氯-3-(三氟甲基)苯磺酰氯的制备及其精制方法 |
| CN119405633A (zh) * | 2024-11-25 | 2025-02-11 | 浙江大学 | 2,6-dmhq在抗心脏和肝脏缺血再灌注损伤中的应用 |
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| RU2367659C2 (ru) | 2003-11-05 | 2009-09-20 | Ф.Хоффманн-Ля Рош Аг | Гетероарильные производные в качестве активаторов рецепторов, активируемых пролифераторами пероксисом (ppar) |
| DE602005024384D1 (de) | 2004-05-05 | 2010-12-09 | High Point Pharmaceuticals Llc | Neue verbindungen, ihre herstellung und verwendung |
| US8053598B2 (en) | 2004-05-05 | 2011-11-08 | High Point Pharmaceuticals, Llc | Compounds, their preparation and use |
| MX2007005205A (es) | 2004-10-29 | 2007-05-11 | Kalypsys Inc | Compuestos biciclicos sulfonilo-sustituidos como moduladores de receptores activados por el proliferador de la peroxisoma. |
| ES2372617T3 (es) | 2005-06-30 | 2012-01-24 | High Point Pharmaceuticals, Llc | Ácidos fenoxiacéticos como activadores de ppar-delta. |
| WO2007005455A2 (en) * | 2005-06-30 | 2007-01-11 | Bayer Cropscience Ag | Improved process for preparing (disubstitutedpropenyl) phenylalkyl substituted heterocycles |
| US7915316B2 (en) * | 2005-08-22 | 2011-03-29 | Allergan, Inc | Sulfonamides |
| AU2006296004B2 (en) * | 2005-09-27 | 2011-11-17 | Shionogi & Co., Ltd. | Sulfonamide derivative having PGD2 receptor antagonistic activity |
| CN101273013B (zh) * | 2005-09-27 | 2013-06-12 | 盐野义制药株式会社 | 具有pgd2受体拮抗活性的磺酰胺衍生物 |
| EP1940815B1 (en) | 2005-10-25 | 2018-08-15 | Kalypsys, Inc. | Salts of modulators of ppar and methods of treating metabolic disorders |
| CN103224477A (zh) | 2005-12-22 | 2013-07-31 | 高点制药有限责任公司 | 作为PPAR-δ活化剂的苯氧基乙酸 |
| US7943612B2 (en) | 2006-03-09 | 2011-05-17 | High Point Pharmaceuticals, Llc | Compounds that modulate PPAR activity, their preparation and use |
| JP5189345B2 (ja) * | 2006-11-06 | 2013-04-24 | 東ソー株式会社 | トリフルオロメチル化用反応試剤 |
| WO2008091863A1 (en) | 2007-01-23 | 2008-07-31 | Kalypsys, Inc. | Sulfonyl-substituted bicyclic compounds as ppar modulators for the treatment of non-alcoholic steatohepatitis |
| KR101152659B1 (ko) * | 2009-10-09 | 2012-06-15 | 한국과학기술연구원 | 세로토닌 수용체 길항 작용과 세로토닌 트랜스포터 억제 작용을 동시에 가지는 설폰아마이드 화합물 |
| RU2013114390A (ru) | 2010-08-31 | 2014-10-10 | СНУ Ар энд ДиБи ФАУНДЕЙШН | Применение фетального репрограммирования посредством ppar-дельта-агониста |
| JP5767458B2 (ja) * | 2010-11-09 | 2015-08-19 | スガイ化学工業株式会社 | ポリオキシエチレン付加カリックスアレーン誘導体の製造方法 |
| BR112014016450A2 (pt) | 2012-01-10 | 2019-09-24 | Lilly Co Eli | composto antagonista de leucotrieno b4 |
| EP3756661A1 (en) | 2013-09-09 | 2020-12-30 | vTv Therapeutics LLC | Use of a ppar-delta agonist for treating muscle atrophy |
| WO2016057322A1 (en) | 2014-10-08 | 2016-04-14 | Salk Institute For Biological Studies | Ppar agonists and methods of use thereof |
| US10188627B2 (en) | 2014-10-08 | 2019-01-29 | Mitobridge, Inc. | PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof |
| US10103402B2 (en) * | 2015-12-01 | 2018-10-16 | University Of Kentucky Research Foundation | Liquid phenothiazine catholytes for non-aqueous redox flow batteries |
| WO2023147309A1 (en) | 2022-01-25 | 2023-08-03 | Reneo Pharmaceuticals, Inc. | Use of ppar-delta agonists in the treatment of disease |
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| US5084466A (en) * | 1989-01-31 | 1992-01-28 | Hoffmann-La Roche Inc. | Novel carboxamide pyridine compounds which have useful pharmaceutical utility |
| US5089514A (en) * | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
| JPH05125038A (ja) * | 1991-03-07 | 1993-05-21 | Tanabe Seiyaku Co Ltd | フエノキシアルカン酸誘導体及びその製法 |
| JPH05194370A (ja) * | 1992-01-22 | 1993-08-03 | Taisho Pharmaceut Co Ltd | スルホンアミド誘導体 |
| US5232945A (en) * | 1992-07-20 | 1993-08-03 | Pfizer Inc. | 3-aryl-2-hydroxypropionic acid derivatives and analogs as antihypertensives |
| JPH0672867A (ja) * | 1992-08-27 | 1994-03-15 | Tanabe Seiyaku Co Ltd | 抗脂血剤 |
| US5902726A (en) * | 1994-12-23 | 1999-05-11 | Glaxo Wellcome Inc. | Activators of the nuclear orphan receptor peroxisome proliferator-activated receptor gamma |
| US6062509A (en) | 1994-12-23 | 2000-05-16 | Hexcel Corporation | Retrofit centerline luggage bin assemblies compatible with existing aircraft bin supports |
| KR19980702372A (ko) * | 1995-02-21 | 1998-07-15 | 구니이 야쓰오 | 글루타민산 수용체 작용약 |
| EP0888278B1 (en) | 1996-02-02 | 2003-07-23 | Merck & Co., Inc. | Antidiabetic agents |
| GB9604242D0 (en) | 1996-02-28 | 1996-05-01 | Glaxo Wellcome Inc | Chemical compounds |
| CA2318731C (en) * | 1998-01-29 | 2012-05-29 | Tularik Inc. | Ppar-gamma modulators |
| ATE451346T1 (de) * | 1998-03-10 | 2009-12-15 | Ono Pharmaceutical Co | Carbonsäurederivate und medikamente die diese als aktiven wirkstoff enthalten |
| GB9822473D0 (en) * | 1998-10-16 | 1998-12-09 | Glaxo Group Ltd | Chemical compounds |
| US6248781B1 (en) * | 1998-10-21 | 2001-06-19 | Novo Nordisk A/S | Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) |
| PL351898A1 (en) * | 1999-04-06 | 2003-06-30 | Sankyo Co | O-substituted derivatives of carboxylic acids |
| NZ515086A (en) * | 1999-04-28 | 2003-10-31 | Aventis Pharma Gmbh | Di-aryl acid derivatives as PPAR receptor ligands |
| TNSN00139A1 (fr) | 1999-06-25 | 2005-11-10 | Inst For Pharm Discovery Inc | Acides phenoxyacetiques substitues |
| DE60005973T2 (de) | 1999-08-27 | 2004-05-13 | Eli Lilly And Co., Indianapolis | Biaryl-oxa(thia)zolderivate und ihre verwendung als ppars modulatoren |
| TWI262185B (en) | 1999-10-01 | 2006-09-21 | Eisai Co Ltd | Carboxylic acid derivatives having anti-hyperglycemia and anti-hyperlipemia action, and pharmaceutical composition containing the derivatives |
| AU7995300A (en) * | 1999-10-05 | 2001-05-10 | Bethesda Pharmaceuticals, Inc. | Dithiolane derivatives |
| PE20011010A1 (es) * | 1999-12-02 | 2001-10-18 | Glaxo Group Ltd | Oxazoles y tiazoles sustituidos como agonista del receptor activado por el proliferador de peroxisomas humano |
| JP4316787B2 (ja) | 2000-01-11 | 2009-08-19 | 壽製薬株式会社 | エーテル又はアミド誘導体、その製法並びにそれを含有する糖尿病治療剤、 |
| DE60129712T2 (de) | 2000-08-23 | 2008-07-03 | Eli Lilly And Co., Indianapolis | Oxazolylaryloxyessigsäure derivate und ihre verwendung als ppar agonisten |
| EP1313717B1 (en) | 2000-08-23 | 2007-10-17 | Eli Lilly And Company | Oxazolyl-arylpropionic acid derivatives and their use as ppar agonists |
| US7071220B2 (en) * | 2000-09-18 | 2006-07-04 | Toa Eiyo Ltd. | N-substituted benzothiophenesulfonamide derivatives |
| WO2002060388A2 (en) * | 2001-01-30 | 2002-08-08 | Merck & Co., Inc. | Acyl sulfamides for treatment of obesity, diabetes and lipid disorders |
| WO2002064130A1 (en) * | 2001-02-15 | 2002-08-22 | Pfizer Products Inc. | Proliferative activator receptor (ppar) compounds |
| MXPA03011201A (es) | 2001-06-07 | 2004-02-26 | Lilly Co Eli | Moduladores de receptores activados por proliferadores de persoxisomas. |
| ATE375350T1 (de) | 2002-02-21 | 2007-10-15 | Lilly Co Eli | Modulatoren von peroxisome proliferator- aktivierten rezeptoren |
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2004
- 2004-02-10 CN CNA2004800042507A patent/CN1751037A/zh active Pending
- 2004-02-10 CA CA002512883A patent/CA2512883A1/en not_active Abandoned
- 2004-02-10 AT AT04709806T patent/ATE382043T1/de not_active IP Right Cessation
- 2004-02-10 MX MXPA05008581A patent/MXPA05008581A/es active IP Right Grant
- 2004-02-10 JP JP2006502992A patent/JP2006520755A/ja active Pending
- 2004-02-10 AU AU2004212887A patent/AU2004212887A1/en not_active Abandoned
- 2004-02-10 DE DE602004010889T patent/DE602004010889T2/de not_active Expired - Fee Related
- 2004-02-10 ES ES04709806T patent/ES2297382T3/es not_active Expired - Lifetime
- 2004-02-10 BR BR0407180-8A patent/BRPI0407180A/pt not_active Application Discontinuation
- 2004-02-10 US US10/542,579 patent/US7655641B2/en not_active Expired - Fee Related
- 2004-02-10 WO PCT/US2004/002015 patent/WO2004073606A2/en not_active Ceased
- 2004-02-10 EP EP04709806A patent/EP1597248B1/en not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102336689A (zh) * | 2011-08-29 | 2012-02-01 | 天津市筠凯化工科技有限公司 | 4-氯-3-(三氟甲基)苯磺酰氯的制备及其精制方法 |
| CN119405633A (zh) * | 2024-11-25 | 2025-02-11 | 浙江大学 | 2,6-dmhq在抗心脏和肝脏缺血再灌注损伤中的应用 |
| CN119405633B (zh) * | 2024-11-25 | 2025-12-02 | 浙江大学 | 2,6-dmhq在抗心脏和肝脏缺血再灌注损伤中的应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| ATE382043T1 (de) | 2008-01-15 |
| DE602004010889D1 (de) | 2008-02-07 |
| WO2004073606A3 (en) | 2005-03-31 |
| BRPI0407180A (pt) | 2006-02-07 |
| JP2006520755A (ja) | 2006-09-14 |
| US7655641B2 (en) | 2010-02-02 |
| DE602004010889T2 (de) | 2008-12-11 |
| ES2297382T3 (es) | 2008-05-01 |
| US20060217433A1 (en) | 2006-09-28 |
| MXPA05008581A (es) | 2005-11-04 |
| EP1597248A2 (en) | 2005-11-23 |
| EP1597248B1 (en) | 2007-12-26 |
| WO2004073606A2 (en) | 2004-09-02 |
| CA2512883A1 (en) | 2004-09-02 |
| AU2004212887A1 (en) | 2004-09-02 |
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