US5019556A
(en)
*
|
1987-04-14 |
1991-05-28 |
President And Fellows Of Harvard College |
Inhibitors of angiogenin
|
CA1340323C
(en)
*
|
1988-09-20 |
1999-01-19 |
Arnold E. Hampel |
Rna catalyst for cleaving specific rna sequences
|
US5866701A
(en)
*
|
1988-09-20 |
1999-02-02 |
The Board Of Regents For Northern Illinois University Of Dekalb |
HIV targeted hairpin ribozymes
|
US5168053A
(en)
*
|
1989-03-24 |
1992-12-01 |
Yale University |
Cleavage of targeted RNA by RNAase P
|
US5624824A
(en)
*
|
1989-03-24 |
1997-04-29 |
Yale University |
Targeted cleavage of RNA using eukaryotic ribonuclease P and external guide sequence
|
DE4091533T
(de)
*
|
1989-08-31 |
1992-01-30 |
|
|
US5225347A
(en)
*
|
1989-09-25 |
1993-07-06 |
Innovir Laboratories, Inc. |
Therapeutic ribozyme compositions and expression vectors
|
US5225337A
(en)
*
|
1989-09-25 |
1993-07-06 |
Innovir Laboratories, Inc. |
Ribozyme compositions and methods for use
|
DE3933384A1
(de)
*
|
1989-10-06 |
1991-04-18 |
Hoechst Ag |
Multifunktionelle rna mit selbstprozessierungsaktivitaet, ihre herstellung und ihre verwendung
|
DE3935473A1
(de)
*
|
1989-10-25 |
1991-05-02 |
Hoechst Ag |
Rna mit endonuclease- und antisense-aktivitaet, ihre herstellung und ihre verwendung
|
DE69133405T2
(de)
*
|
1990-01-11 |
2005-07-07 |
Isis Pharmaceutical, Inc., Carlsbad |
Oligonukleotidderivate zur detektieren und modulation von rna aktivität und genexpression
|
US5519164A
(en)
*
|
1990-02-01 |
1996-05-21 |
Hoechst Aktiengesellschaft |
Expression of a multigene RNA having self-splicing activity
|
DE4002885A1
(de)
*
|
1990-02-01 |
1991-08-08 |
Hoechst Ag |
Expression einer multigen rna mit self-splicing aktivitaet
|
US5180818A
(en)
*
|
1990-03-21 |
1993-01-19 |
The University Of Colorado Foundation, Inc. |
Site specific cleavage of single-stranded dna
|
WO1991018913A1
(en)
*
|
1990-06-07 |
1991-12-12 |
City Of Hope |
Ribozyme mediated reversal of transformation by cleavage of the hras oncogene rna
|
AU7152191A
(en)
*
|
1990-06-07 |
1991-12-31 |
City Of Hope |
Ribozyme mediated reversal of transformation by cleavage of the hras oncogene rna
|
US6008343A
(en)
*
|
1990-06-19 |
1999-12-28 |
Gene Shears Pty. Ltd. |
Nucleotide based endonucleases
|
ATE150789T1
(de)
*
|
1990-06-19 |
1997-04-15 |
Gene Shears Pty Ltd |
Endonukleasen
|
US5246921A
(en)
*
|
1990-06-26 |
1993-09-21 |
The Wistar Institute Of Anatomy And Biology |
Method for treating leukemias
|
WO1992000080A1
(en)
*
|
1990-06-26 |
1992-01-09 |
The Wistar Institute Of Anatomy & Biology |
Method for treating leukemias
|
CA2088154A1
(en)
*
|
1990-07-26 |
1992-01-27 |
Martin Tabler |
Portable ribozyme cassettes, dna sequences containing them, ribozyme encoded by these dna sequences, and compositions containing these ribozymes
|
JP3257675B2
(ja)
*
|
1990-10-12 |
2002-02-18 |
マックス−プランク−ゲゼルシャフト ツール フェルデルング デル ビッセンシャフテン エー.ファウ. |
修飾リボザイム
|
NZ241310A
(en)
*
|
1991-01-17 |
1995-03-28 |
Gen Hospital Corp |
Trans-splicing ribozymes
|
NZ314630A
(en)
*
|
1991-01-17 |
2000-11-24 |
Harvard College |
Use of trans-splicing ribozymes for genetic modification and cell ablation in a host cell
|
FR2675803B1
(fr)
*
|
1991-04-25 |
1996-09-06 |
Genset Sa |
Oligonucleotides fermes, antisens et sens et leurs applications.
|
FI913197A0
(fi)
|
1991-07-01 |
1991-07-01 |
Xyrofin Oy |
Nya jaeststammar med reducerad foermaoga att metabolisera xylitol, foerfarande foer bildande av dessa och deras anvaendning vid framstaellning av xylitol.
|
WO1993014218A1
(en)
*
|
1992-01-13 |
1993-07-22 |
Duke University |
Enzymatic rna molecules
|
AU656676B2
(en)
*
|
1992-04-17 |
1995-02-09 |
Kirin Beer Kabushiki Kaisha |
Plant resistant to two or more viruses and preparation thereof
|
HUT71929A
(en)
*
|
1992-06-29 |
1996-02-28 |
Gene Shears Pty Ltd |
Nucleic acids and methods of use thereof for controlling viral pathogens
|
EP0653488B1
(de)
*
|
1992-07-02 |
2003-04-09 |
Sankyo Company Limited |
Haarnadelförmiges ribozym
|
US5409823A
(en)
*
|
1992-09-24 |
1995-04-25 |
Ciba-Geigy Corporation |
Methods for the production of hybrid seed
|
ATE269405T1
(de)
*
|
1992-11-03 |
2004-07-15 |
Gene Shears Pty Ltd |
Tnf-alpha ribozyme und abbau-resistente mrna derivative gebunden an tnf-alpha ribozyme
|
US5864028A
(en)
*
|
1992-11-03 |
1999-01-26 |
Gene Shears Pty. Limited |
Degradation resistant mRNA derivatives linked to TNF-α ribozymes
|
JP3595841B2
(ja)
*
|
1992-12-04 |
2004-12-02 |
サーナ セラピューティクス,インコーポレイテッド |
リボザイム増幅診断用薬
|
JPH08507203A
(ja)
*
|
1992-12-04 |
1996-08-06 |
イノーバー ラボラトリーズ,インコーポレイテッド |
調節可能な核酸治療およびそれらの使用方法
|
JPH08506724A
(ja)
*
|
1992-12-04 |
1996-07-23 |
アポロン・インコーポレーテッド |
白血病治療のための化合物および方法
|
FR2701960B1
(fr)
*
|
1993-02-26 |
2002-09-13 |
Gene Shears Pty Ltd |
Polyribozyme apte à conférer, aux plantes, une résistance aux virus et plantes résistantes produisant ce polyribozyme.
|
US5817635A
(en)
*
|
1993-08-09 |
1998-10-06 |
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. |
Modified ribozymes
|
WO1995010608A1
(en)
*
|
1993-10-15 |
1995-04-20 |
Foundation For Research And Technology - Hellas (Fo.R.T.H.) |
Asymmetric hammerhead ribozymes and nucleotide sequences for their construction
|
US5869248A
(en)
*
|
1994-03-07 |
1999-02-09 |
Yale University |
Targeted cleavage of RNA using ribonuclease P targeting and cleavage sequences
|
US5998193A
(en)
*
|
1994-06-24 |
1999-12-07 |
Gene Shears Pty., Ltd. |
Ribozymes with optimized hybridizing arms, stems, and loops, tRNA embedded ribozymes and compositions thereof
|
US6350934B1
(en)
|
1994-09-02 |
2002-02-26 |
Ribozyme Pharmaceuticals, Inc. |
Nucleic acid encoding delta-9 desaturase
|
US5683873A
(en)
*
|
1995-01-13 |
1997-11-04 |
Innovir Laboratories, Inc. |
EGS-mediated inactivation of target RNA
|
US6057153A
(en)
*
|
1995-01-13 |
2000-05-02 |
Yale University |
Stabilized external guide sequences
|
FR2730637B1
(fr)
|
1995-02-17 |
1997-03-28 |
Rhone Poulenc Rorer Sa |
Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
|
US6010904A
(en)
*
|
1995-06-07 |
2000-01-04 |
The General Hospital Corporation |
Cell ablation using trans-splicing ribozymes
|
US6004806A
(en)
*
|
1995-06-07 |
1999-12-21 |
Commonwealth Scientific And Industrial Research Organization |
Optimized minizymes and miniribozymes and uses thereof
|
EP0837933A4
(de)
*
|
1995-06-07 |
2003-05-21 |
Commw Scient Ind Res Org |
Optimierte minizyme und miniribozyme und deren anwendungen
|
CN1196091A
(zh)
*
|
1995-07-13 |
1998-10-14 |
里伯希姆药品公司 |
用于在植物中调节基因表达的组合物和方法
|
US5824519A
(en)
*
|
1995-11-08 |
1998-10-20 |
Medical University Of South Carolina |
Tissue-specific and target RNA-specific ribozymes
|
US5877162A
(en)
*
|
1996-03-14 |
1999-03-02 |
Innovir Laboratories, Inc. |
Short external guide sequences
|
US6620805B1
(en)
|
1996-03-14 |
2003-09-16 |
Yale University |
Delivery of nucleic acids by porphyrins
|
US6610478B1
(en)
|
1996-08-16 |
2003-08-26 |
Yale University |
Phenotypic conversion of cells mediated by external guide sequences
|
US5976874A
(en)
*
|
1996-08-16 |
1999-11-02 |
Yale University |
Phenotypic conversion of drug-resistant bacteria to drug-sensitivity
|
US6884430B1
(en)
|
1997-02-10 |
2005-04-26 |
Aventis Pharma S.A. |
Formulation of stabilized cationic transfection agent(s) /nucleic acid particles
|
US7083786B2
(en)
|
1997-04-03 |
2006-08-01 |
Jensenius Jens Chr |
MASP-2, a complement-fixing enzyme, and uses for it
|
US7589253B2
(en)
|
1997-04-15 |
2009-09-15 |
Commonwealth Scientific And Industrial Research Organisation |
Fatty acid epoxygenase genes from plants and uses therefor in modifying fatty acid metabolism
|
DK0975765T3
(da)
|
1997-04-15 |
2007-02-19 |
Commw Scient Ind Res Org |
Plantefedtsyre-epoxygenase-gener og anvendelse deraf
|
CZ299473B6
(cs)
|
1997-06-30 |
2008-08-06 |
Rhone-Poulenc Rorer S. A. |
Nukleová kyselina a elektrické pole jako sdruženýprodukt pro prenos nukleové kyseliny do bunek prícne pruhovaného svalstva
|
JP2001516582A
(ja)
|
1997-09-16 |
2001-10-02 |
クロップデザイン エヌ.ブイ. |
サイクリン依存性キナーゼ阻害物質およびその使用
|
DE19741375C2
(de)
*
|
1997-09-19 |
1999-10-21 |
Max Planck Gesellschaft |
Transgene Pflanzen, deren oberirdische Teile früher reifen und vollständig absterben
|
JP4891477B2
(ja)
|
1997-10-02 |
2012-03-07 |
マックス−プランク−ゲゼルシャフト ツール フォーデルング デル ヴィッセンシャフテン エー.ヴェー. |
血管新生及び/または既存細動脈網から側枝動脈及び/または他の動脈の発達の調節に関する方法
|
WO1999025815A2
(en)
|
1997-11-18 |
1999-05-27 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Nucleic acids involved in the responder phenotype and applications thereof
|
US6013447A
(en)
*
|
1997-11-21 |
2000-01-11 |
Innovir Laboratories, Inc. |
Random intracellular method for obtaining optimally active nucleic acid molecules
|
CA2487328A1
(en)
|
1998-03-20 |
1999-09-30 |
Benitec Australia Ltd. |
Sirna for control of gene expression
|
AUPP249298A0
(en)
|
1998-03-20 |
1998-04-23 |
Ag-Gene Australia Limited |
Synthetic genes and genetic constructs comprising same I
|
US6248525B1
(en)
|
1998-03-30 |
2001-06-19 |
Yale University |
Method for identifying essential or functional genes
|
WO1999067400A1
(en)
|
1998-06-24 |
1999-12-29 |
Musc Foundation For Research Development |
Tissue-specific and target rna-specific ribozymes
|
DE19836098A1
(de)
|
1998-07-31 |
2000-02-03 |
Hoechst Schering Agrevo Gmbh |
Pflanzen, die eine modifizierte Stärke synthetisieren, Verfahren zur Herstellung der Pflanzen, ihre Verwendung sowie die modifizierte Stärke
|
EP1953229A3
(de)
|
1998-10-15 |
2008-12-24 |
Novartis Vaccines and Diagnostics, Inc. |
Metastatische Brust- und Dickdarmkrebs-regulierte Gene
|
JP2002529094A
(ja)
|
1998-11-09 |
2002-09-10 |
プランテック バイオテクノロジー ゲーエムベーハー |
コメ由来核酸分子および改変デンプンの生産のためのその使用
|
CA2350398C
(en)
|
1998-11-12 |
2010-08-10 |
Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. |
Chimeric promoters capable of mediating gene expression in plants upon pathogen infection and uses thereof
|
ATE519840T1
(de)
|
1998-12-16 |
2011-08-15 |
Novartis Vaccines & Diagnostic |
Menschliche cyclin-abhängige kinase (hpnqalre)
|
US6271359B1
(en)
|
1999-04-14 |
2001-08-07 |
Musc Foundation For Research Development |
Tissue-specific and pathogen-specific toxic agents and ribozymes
|
AUPQ005299A0
(en)
|
1999-04-29 |
1999-05-27 |
Commonwealth Scientific And Industrial Research Organisation |
Novel genes encoding wheat starch synthases and uses therefor
|
WO2001005221A1
(en)
|
1999-07-20 |
2001-01-25 |
Ges. Für Erwerb Und Verwertung Von Schutzrechten-Gvs Mbh |
Novel method for the generation and selection of transgenic linseed/flax plants
|
US6423885B1
(en)
|
1999-08-13 |
2002-07-23 |
Commonwealth Scientific And Industrial Research Organization (Csiro) |
Methods for obtaining modified phenotypes in plant cells
|
DK1301213T3
(en)
|
2000-07-21 |
2017-03-27 |
Revance Therapeutics Inc |
MULTI-COMPONENT SYSTEMS FOR BIOLOGICAL TRANSPORT
|
PT1331845E
(pt)
|
2000-11-09 |
2012-04-12 |
Commw Scient Ind Res Org |
Cevada com reduzida atividade ssii e produtos contendo amido com um conteúdo de amilopectina reduzido
|
ITMI20011364A1
(it)
*
|
2001-06-28 |
2002-12-28 |
Metapontum Agrobios S C R L |
Robozima hammerhead specifico per la stearoyl-acp desaturesi di piante oleaginose differenti
|
AU2002316640C1
(en)
|
2001-07-10 |
2009-01-29 |
Johnson & Johnson Research Pty Limited |
Methods for genetic modification of hematopoietic progenitor cells and uses of the modified cells
|
US7994144B2
(en)
|
2001-07-10 |
2011-08-09 |
Johnson & Johnson Research Pty, Limited |
Process for the preparation of a composition of genetically modified hematopoietic progenitor cells
|
US8022272B2
(en)
|
2001-07-13 |
2011-09-20 |
Sungene Gmbh & Co. Kgaa |
Expression cassettes for transgenic expression of nucleic acids
|
FR2829136B1
(fr)
|
2001-08-29 |
2006-11-17 |
Aventis Pharma Sa |
Derives lipidiques d'aminoglycosides
|
US7456335B2
(en)
|
2001-09-03 |
2008-11-25 |
Basf Plant Science Gmbh |
Nucleic acid sequences and their use in methods for achieving pathogen resistance in plants
|
EP2284195A1
(de)
|
2001-09-18 |
2011-02-16 |
Carnegie Institution Of Washington |
Fusionsproteine zur Detektion von Analyten
|
AU2002359761A1
(en)
|
2001-12-18 |
2003-06-30 |
Invenux, Inc. |
Antibiotic compounds
|
US20040005546A1
(en)
|
2002-02-28 |
2004-01-08 |
Oncolytics Biotech Inc. |
Use of ribozymes in the detection of adventitious agents
|
DE10212892A1
(de)
|
2002-03-20 |
2003-10-09 |
Basf Plant Science Gmbh |
Konstrukte und Verfahren zur Regulation der Genexpression
|
EP1900827A3
(de)
|
2002-05-21 |
2008-04-16 |
Bayer HealthCare AG |
Verfahren und Zusammensetzungen zur Vorhersage, Diagnose, Prognose, Verhinderung und Behandlung maligner Neoplasien
|
AU2003280420A1
(en)
|
2002-06-26 |
2004-01-19 |
Yale University |
Modulators and modulation of the interacton between rgm and neogenin
|
DE50310378D1
(de)
|
2002-07-26 |
2008-10-02 |
Basf Plant Science Gmbh |
Neue selektionsverfahren
|
EP2258724A1
(de)
|
2002-11-21 |
2010-12-08 |
Celltech R & D, Inc. |
Modulierung von Immunantworten mittels multimeriserter Anti-CD83 Antikörper
|
ES2310256T3
(es)
|
2002-12-19 |
2009-01-01 |
Bayer Cropscience Ag |
Celulas de plantas y plantas que sintetizan un almidon con una viscosidad final incrementada.
|
SI1625166T1
(sl)
|
2003-05-12 |
2015-08-31 |
Helion Biotech Aps |
Protitelesa masp-2
|
WO2005001098A1
(en)
|
2003-06-30 |
2005-01-06 |
Commonwealth Scientific And Industrial Research Organisation |
Wheat with altered branching enzyme activity and starch and starch containing products derived thereform
|
EP1522594A3
(de)
|
2003-10-06 |
2005-06-22 |
Bayer HealthCare AG |
Verfahren und kit zur untersuchung von krebs
|
EP1602926A1
(de)
|
2004-06-04 |
2005-12-07 |
University of Geneva |
Neue Mittel und Verfahren zur Behandlung von Gehörverlust oder Tinnitus
|
US7604947B2
(en)
|
2004-06-09 |
2009-10-20 |
Cornell Research Foundation, Inc. |
Detection and modulation of cancer stem cells
|
US8840893B2
(en)
|
2004-06-10 |
2014-09-23 |
Omeros Corporation |
Methods for treating conditions associated with MASP-2 dependent complement activation
|
LT1753456T
(lt)
|
2004-06-10 |
2016-11-10 |
Omeros Corporation |
Ligų, susijusių su nuo masp-2 priklausomu komplemento aktyvinimu, gydymo būdai
|
US7919094B2
(en)
|
2004-06-10 |
2011-04-05 |
Omeros Corporation |
Methods for treating conditions associated with MASP-2 dependent complement activation
|
DK1763582T3
(en)
|
2004-07-08 |
2015-01-12 |
Dlf Trifolium As |
Means and method of controlling the flowering of plants
|
WO2006013072A2
(en)
|
2004-08-02 |
2006-02-09 |
Basf Plant Science Gmbh |
Method for isolation of transcription termination sequences
|
CA2579927A1
(en)
|
2004-09-24 |
2006-03-30 |
Basf Plant Science Gmbh |
Plant cells and plants with increased tolerance to environmental stress
|
JP5638736B2
(ja)
|
2004-12-30 |
2014-12-10 |
コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション |
腸の健康を改善する方法および手段
|
EP1707632A1
(de)
|
2005-04-01 |
2006-10-04 |
Bayer CropScience GmbH |
Phosphorylierte waxy-Kartoffelstärke
|
WO2007039256A2
(de)
|
2005-09-30 |
2007-04-12 |
Abbott Gmbh & Co. Kg |
Bindungsdomänen von proteinen der repulsive guidance molecule (rgm) proteinfamilie und funktionale fragmente davon sowie deren verwendung
|
CA2628505A1
(en)
|
2005-11-08 |
2007-05-18 |
Basf Plant Science Gmbh |
Use of armadillo repeat (arm1) polynucleotides for obtaining resistance to pathogens in plants
|
US8178751B2
(en)
|
2006-01-12 |
2012-05-15 |
Basf Plant Science Gmbh |
Use of stomatin (STM1) polynucleotides for achieving a pathogen resistance in plants
|
CA2644273A1
(en)
|
2006-04-05 |
2008-03-27 |
Metanomics Gmbh |
Process for the production of a fine chemical
|
EP2030021B1
(de)
|
2006-05-18 |
2012-11-21 |
Andreas Reichert |
Verfahren zur diagnose mitochondrialer fehlfunktion
|
US8383597B2
(en)
|
2006-05-25 |
2013-02-26 |
Cornell Research Foundation, Inc. |
G proteins in tumor growth and angiogenesis
|
AU2007304837B2
(en)
|
2006-10-06 |
2011-09-29 |
Speedx Pty Ltd |
Molecular switches and methods for their use
|
US8592652B2
(en)
|
2007-01-15 |
2013-11-26 |
Basf Plant Science Gmbh |
Use of subtilisin-like RNR9 polynucleotide for achieving pathogen resistance in plants
|
EP2074219B1
(de)
|
2007-02-16 |
2013-11-20 |
BASF Plant Science GmbH |
Nukleinsäuresequenzen zur regulierung embryospezifischer expression in einkeimblättrigen pflanzen
|
AU2008230710B2
(en)
|
2007-03-27 |
2014-04-10 |
Omeros Corporation |
The use of PDE7 inhibitors for the treatment of movement disorders
|
WO2008142036A2
(en)
|
2007-05-22 |
2008-11-27 |
Basf Plant Science Gmbh |
Plant cells and plants with increased tolerance and/or resistance to environmental stress and increased biomass production-ko
|
CL2008002775A1
(es)
|
2007-09-17 |
2008-11-07 |
Amgen Inc |
Uso de un agente de unión a esclerostina para inhibir la resorción ósea.
|
EP2040075A1
(de)
|
2007-09-24 |
2009-03-25 |
Julius-Maximilians-Universität Würzburg |
Verbindungen und Marker für oberflächenverstärkte Raman-Streuung
|
CN101896201A
(zh)
|
2007-12-14 |
2010-11-24 |
安进公司 |
使用抗硬骨素抗体治疗骨折的方法
|
AU2008340002A1
(en)
|
2007-12-21 |
2009-07-02 |
Basf Plant Science Gmbh |
Plants with increased yield (KO NUE)
|
US8962803B2
(en)
|
2008-02-29 |
2015-02-24 |
AbbVie Deutschland GmbH & Co. KG |
Antibodies against the RGM A protein and uses thereof
|
EP2100962A1
(de)
|
2008-03-12 |
2009-09-16 |
Biogemma |
Pflanzen mit verbesserter Widerstandsfähigkeit gegen Pathogene
|
US10517839B2
(en)
|
2008-06-09 |
2019-12-31 |
Cornell University |
Mast cell inhibition in diseases of the retina and vitreous
|
EP2331071A1
(de)
|
2008-09-05 |
2011-06-15 |
Institut National De La Sante Et De La Recherche Medicale |
Neue multimodulare anordnung zur intrazellulären abgabe
|
EP2184351A1
(de)
|
2008-10-30 |
2010-05-12 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Polynukleotid-kondierende Caryophyllen-Synthase und ihre Verwendung
|
ES2363358B1
(es)
|
2009-04-03 |
2012-06-21 |
FUNDACIÓ INSTITUT DE RECERCA HOSPITAL UNIVERSITARI VALL D'HEBRON (Titular al |
Agentes terapéuticos para el tratamiento de enfermedades asociadas con una proliferación celular indeseable.
|
DE112010003162T5
(de)
|
2009-04-22 |
2012-08-16 |
Basf Plant Science Company Gmbh |
Gesamtsamen-spezifischer Promotor
|
US20130012709A1
(en)
|
2009-09-10 |
2013-01-10 |
Centre National De La Recherche Scientifique |
NOVEL INHIBITORS OF STEAROYL-CoA-DESATURASE-1 AND THEIR USES
|
EP2305285A1
(de)
|
2009-09-29 |
2011-04-06 |
Julius-Maximilians-Universität Würzburg |
Mittel und Verfahren zur Behandlung von ischämischen Erkrankungen
|
JP5911804B2
(ja)
|
2009-10-16 |
2016-04-27 |
オメロス コーポレーション |
Masp−2依存性の補体活性化を阻害することによって播種性血管内凝固を処置するための方法
|
CA2779073C
(en)
|
2009-10-30 |
2017-10-24 |
Domain Therapeutics |
Novel oxime derivatives and their use as allosteric modulators of metabotropic glutamate receptors
|
EP2322149A1
(de)
|
2009-11-03 |
2011-05-18 |
Universidad del Pais Vasco |
Verfahren und Zusammensetzung zur Behandlung von Ischämie
|
CN102656190A
(zh)
|
2009-12-08 |
2012-09-05 |
雅培股份有限两合公司 |
用于在视网膜神经纤维层变性治疗中使用的针对rgm a蛋白质的单克隆抗体
|
EP2338492A1
(de)
|
2009-12-24 |
2011-06-29 |
Universidad del Pais Vasco |
Verfahren und Zusammensetzung zur Behandlung von Alzheimer
|
US8476485B2
(en)
|
2010-06-24 |
2013-07-02 |
Academia Sinica |
Non-human animal model for amyotrophic lateral sclerosis (ALS) with loss-of-TDP-43 function
|
CN103547267A
(zh)
|
2010-11-08 |
2014-01-29 |
奥默罗斯公司 |
使用pde7抑制剂治疗成瘾和冲动控制障碍
|
US9220715B2
(en)
|
2010-11-08 |
2015-12-29 |
Omeros Corporation |
Treatment of addiction and impulse-control disorders using PDE7 inhibitors
|
KR20220044616A
(ko)
|
2011-04-08 |
2022-04-08 |
유니버시티 오브 레스터 |
Masp-2 의존적 보체 활성화와 관련된 질병을 치료하는 방법
|
US9644035B2
(en)
|
2011-04-08 |
2017-05-09 |
Omeros Corporation |
Methods for treating conditions associated with MASP-2 dependent complement activation
|
WO2013025936A1
(en)
|
2011-08-18 |
2013-02-21 |
Cornell University |
Detection and treatment of metastatic disease
|
WO2013039880A1
(en)
|
2011-09-12 |
2013-03-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Biomarkers and therapeutic targets of hepatocellular cancer
|
WO2013090814A2
(en)
|
2011-12-16 |
2013-06-20 |
Board Of Trustees Of Michigan State University |
p-Coumaroyl-CoA:Monolignol Transferase
|
IL305223A
(en)
|
2012-01-27 |
2023-10-01 |
Abbvie Inc |
The composition and method for the diagnosis and treatment of diseases related to the degeneration of nerve cells
|
EP2825209B1
(de)
|
2012-03-14 |
2018-08-29 |
University of Central Florida Research Foundation, Inc. |
Neurofibromatose-therapeutika und screening dafür
|
EP2666775A1
(de)
|
2012-05-21 |
2013-11-27 |
Domain Therapeutics |
Substituierte Pyrazolochinazolinone und Pyrrolochinazolinone als allosterische Modulatoren von metabotropen Glutamatrezeptoren der Gruppe II
|
WO2014127835A1
(en)
|
2013-02-22 |
2014-08-28 |
Christian-Albrechts-Universität Zu Kiel |
Plant-derived resistance gene
|
US9163284B2
(en)
|
2013-08-09 |
2015-10-20 |
President And Fellows Of Harvard College |
Methods for identifying a target site of a Cas9 nuclease
|
CN111588855A
(zh)
|
2013-10-17 |
2020-08-28 |
奥默罗斯公司 |
用于治疗与masp-2依赖性补体活化有关的病况的方法
|
KR102535223B1
(ko)
|
2013-12-18 |
2023-05-30 |
커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 |
장쇄 다중불포화 지방산을 포함하는 지질
|
WO2015196250A1
(en)
|
2014-06-27 |
2015-12-30 |
Commonwealth Scientific And Industrial Research Organisation |
Lipid comprising docosapentaenoic acid
|
EP3000814A1
(de)
|
2014-09-26 |
2016-03-30 |
Domain Therapeutics |
Substituierte Pyrazolochinazolinone und Pyrrolochinazolinone als allosterische Modulatoren von metabotropen Glutamatrezeptoren der Gruppe II
|
CA3185172A1
(en)
|
2016-01-05 |
2017-07-13 |
Omeros Corporation |
Methods for inhibiting fibrosis in a subject in need thereof
|
WO2017173290A1
(en)
|
2016-03-31 |
2017-10-05 |
Omeros Corporation |
Methods for inhibiting angiogenesis in a subject in need thereof
|
CN109476715B
(zh)
|
2016-05-26 |
2023-06-27 |
纽海姆有限公司 |
产无籽果实的植物
|
AU2017308889B2
(en)
|
2016-08-09 |
2023-11-09 |
President And Fellows Of Harvard College |
Programmable Cas9-recombinase fusion proteins and uses thereof
|
WO2018119359A1
(en)
|
2016-12-23 |
2018-06-28 |
President And Fellows Of Harvard College |
Editing of ccr5 receptor gene to protect against hiv infection
|
ES2949801T3
(es)
|
2017-01-09 |
2023-10-03 |
Whitehead Inst Biomedical Res |
Métodos para alterar la expresión génica mediante la perturbación de multímeros de factores de transcripción que estructuran bucles reguladores
|
WO2018165504A1
(en)
|
2017-03-09 |
2018-09-13 |
President And Fellows Of Harvard College |
Suppression of pain by gene editing
|
US10883089B2
(en)
|
2017-04-04 |
2021-01-05 |
Wisconsin Alumni Research Foundation |
Feruloyl-CoA:monolignol transferases
|
US10883090B2
(en)
|
2017-04-18 |
2021-01-05 |
Wisconsin Alumni Research Foundation |
P-coumaroyl-CoA:monolignol transferases
|
CN111447940A
(zh)
|
2017-07-17 |
2020-07-24 |
科罗拉多大学评议会 |
预防或治疗由辐射或放射疗法引起的辐射诱发的旁观者效应的组合物和方法
|
JP2020534795A
(ja)
|
2017-07-28 |
2020-12-03 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
ファージによって支援される連続的進化(pace)を用いて塩基編集因子を進化させるための方法および組成物
|
TWI818919B
(zh)
|
2017-08-15 |
2023-10-21 |
美商歐米諾斯公司 |
用於治療和/ 或預防與造血幹細胞移植有關的移植物抗宿主病和/ 或瀰漫性肺泡出血和/ 或靜脈閉塞性病的方法
|
WO2019139645A2
(en)
|
2017-08-30 |
2019-07-18 |
President And Fellows Of Harvard College |
High efficiency base editors comprising gam
|
US11795443B2
(en)
|
2017-10-16 |
2023-10-24 |
The Broad Institute, Inc. |
Uses of adenosine base editors
|
US11584714B2
(en)
|
2018-05-29 |
2023-02-21 |
Omeros Corporation |
MASP-2 inhibitors and methods of use
|
US11291176B2
(en)
|
2018-06-15 |
2022-04-05 |
Nunhems B.V. |
Seedless watermelon plants comprising modifications in an ABC transporter gene
|
JP2022526908A
(ja)
|
2019-03-19 |
2022-05-27 |
ザ ブロード インスティテュート,インコーポレーテッド |
編集ヌクレオチド配列を編集するための方法および組成物
|
IL293550A
(en)
|
2019-12-04 |
2022-08-01 |
Omeros Corp |
2-masp inhibitor compounds, preparations containing them and their uses
|
AU2021267940A1
(en)
|
2020-05-08 |
2022-12-08 |
President And Fellows Of Harvard College |
Methods and compositions for simultaneous editing of both strands of a target double-stranded nucleotide sequence
|
WO2022034474A1
(en)
|
2020-08-10 |
2022-02-17 |
Novartis Ag |
Treatments for retinal degenerative diseases
|
WO2024038089A1
(en)
|
2022-08-18 |
2024-02-22 |
Mitodicure Gmbh |
Use of a therapeutic agent with phosphodiesterase-7 inhibitory activity for the treatment and prevention of diseases associated with chronic fatigue, exhaustion and/or exertional intolerance
|
WO2024042160A1
(en)
|
2022-08-26 |
2024-02-29 |
Mitodicure Gmbh |
Use of a therapeutic agent with sodium-hydrogen antiporter 1 inhibitory activity for the treatment and prevention of diseases associated with chronic fatigue, exhaustion and/or exertional intolerance
|