DE2807202A1 - Stabile thymosinfraktion 5 und deren herstellung - Google Patents
Stabile thymosinfraktion 5 und deren herstellungInfo
- Publication number
- DE2807202A1 DE2807202A1 DE19782807202 DE2807202A DE2807202A1 DE 2807202 A1 DE2807202 A1 DE 2807202A1 DE 19782807202 DE19782807202 DE 19782807202 DE 2807202 A DE2807202 A DE 2807202A DE 2807202 A1 DE2807202 A1 DE 2807202A1
- Authority
- DE
- Germany
- Prior art keywords
- thymosin fraction
- stable
- preparation
- buffer substance
- antimicrobial agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2292—Thymosin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/770,480 US4082737A (en) | 1977-02-22 | 1977-02-22 | Stabilized thymosin composition and method |
Publications (2)
Publication Number | Publication Date |
---|---|
DE2807202A1 true DE2807202A1 (de) | 1978-08-24 |
DE2807202C2 DE2807202C2 (de) | 1987-04-02 |
Family
ID=25088687
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE2807202A Expired DE2807202C2 (de) | 1977-02-22 | 1978-02-20 | Stabile Thymosinfraktion 5 und deren Herstellung |
Country Status (20)
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2732587A1 (de) * | 1976-09-22 | 1978-03-23 | Bach Jean Francois | Polypeptid mit thymischer wirksamkeit |
US4148788A (en) * | 1978-01-23 | 1979-04-10 | Hoffmann-La Roche Inc. | Synthesis of thymosin α1 |
US4239498A (en) * | 1978-11-27 | 1980-12-16 | Rule Allyn H | Method of preparing thymic factors and composition |
US4264571A (en) * | 1979-01-22 | 1981-04-28 | George Washington University | Radioimmunoassay of thymosin α1 |
EP0057702A1 (en) * | 1980-08-08 | 1982-08-18 | Rak-A-Van Pty Limited | Improved racking |
US4389343A (en) * | 1981-12-24 | 1983-06-21 | Hoffmann-La Roche Inc. | Immunopotentiating peptides from thymus |
US4388234A (en) * | 1981-12-28 | 1983-06-14 | Hoffmann-La Roche Inc. | Peptide isolation |
US4614731A (en) * | 1983-09-15 | 1986-09-30 | Hoffmann-La Roche Inc. | Peptide having immunopotentiating activity similar to thymosin alpha1 |
US4659694A (en) * | 1983-10-27 | 1987-04-21 | Hoffmann-La Roche Inc. | Prothymosin alpha |
US4814434A (en) * | 1984-02-03 | 1989-03-21 | Ventres Laboratories, Inc. | Inducer of T-suppressor cells |
DE3633651A1 (de) * | 1986-10-03 | 1988-04-14 | Alfred Dr Dick | Verwendung von fraktionen aus thymus- und milzextrakten zur behandlung der psoriasis |
US5273963A (en) * | 1991-03-29 | 1993-12-28 | The George Washington University | Compositions and methods for treating small cell and nonsmall cell lung cancers |
JP4404866B2 (ja) | 2006-03-03 | 2010-01-27 | ゼライス株式会社 | エンドトキシン含有量を低減したゼラチンの製造方法および低エンドトキシンゼラチン |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4010148A (en) * | 1975-05-12 | 1977-03-01 | Board Of Regents Of The University Of Texas System | Purified thymosin and process |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4002602A (en) * | 1974-03-11 | 1977-01-11 | Gideon Goldstein | Ubiquitous immunopoietic polypeptide (UBIP) and methods |
US4002740A (en) * | 1975-08-21 | 1977-01-11 | Gideon Goldstein | Tridecapeptide compositions and methods |
-
1977
- 1977-02-22 US US05/770,480 patent/US4082737A/en not_active Expired - Lifetime
-
1978
- 1978-01-18 CH CH51178A patent/CH632164A5/de not_active IP Right Cessation
- 1978-01-30 IT IT19791/78A patent/IT1092337B/it active
- 1978-02-06 CA CA296,326A patent/CA1099633A/en not_active Expired
- 1978-02-07 NL NLAANVRAGE7801422,A patent/NL189281C/xx not_active IP Right Cessation
- 1978-02-15 NZ NZ186489A patent/NZ186489A/xx unknown
- 1978-02-15 ZA ZA00780890A patent/ZA78890B/xx unknown
- 1978-02-16 IE IE335/78A patent/IE46409B1/en not_active IP Right Cessation
- 1978-02-16 IL IL54063A patent/IL54063A0/xx not_active IP Right Cessation
- 1978-02-16 AU AU33343/78A patent/AU516946B2/en not_active Expired
- 1978-02-20 LU LU79090A patent/LU79090A1/xx unknown
- 1978-02-20 DE DE2807202A patent/DE2807202C2/de not_active Expired
- 1978-02-20 FR FR7804718A patent/FR2380782A1/fr active Granted
- 1978-02-20 JP JP1774678A patent/JPS53104719A/ja active Granted
- 1978-02-21 SE SE7802014A patent/SE444647B/sv unknown
- 1978-02-21 DK DK78378A patent/DK78378A/da unknown
- 1978-02-21 GB GB6845/78A patent/GB1546027A/en not_active Expired
- 1978-02-21 PH PH20803A patent/PH13858A/en unknown
- 1978-02-21 BE BE185321A patent/BE864139A/xx not_active IP Right Cessation
- 1978-02-21 AT AT0124578A patent/AT363177B/de not_active IP Right Cessation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4010148A (en) * | 1975-05-12 | 1977-03-01 | Board Of Regents Of The University Of Texas System | Purified thymosin and process |
Non-Patent Citations (2)
Title |
---|
US-Z: Acad.Sci., 56, 1966, S. 1010-1017 * |
US-Z: Chem.Abstr., 68, 1967, Ref. 8518 * |
Also Published As
Publication number | Publication date |
---|---|
JPS53104719A (en) | 1978-09-12 |
IT1092337B (it) | 1985-07-06 |
FR2380782A1 (fr) | 1978-09-15 |
NZ186489A (en) | 1981-01-23 |
DE2807202C2 (de) | 1987-04-02 |
GB1546027A (en) | 1979-05-16 |
DK78378A (da) | 1978-08-23 |
JPS618806B2 (US07655688-20100202-C00010.png) | 1986-03-18 |
AT363177B (de) | 1981-07-10 |
PH13858A (en) | 1980-10-22 |
NL189281C (nl) | 1993-03-01 |
US4082737A (en) | 1978-04-04 |
SE7802014L (sv) | 1978-08-23 |
NL189281B (nl) | 1992-10-01 |
AU516946B2 (en) | 1981-07-02 |
AU3334378A (en) | 1979-08-23 |
BE864139A (fr) | 1978-08-21 |
SE444647B (sv) | 1986-04-28 |
IL54063A0 (en) | 1978-04-30 |
ZA78890B (en) | 1979-01-31 |
IT7819791A0 (it) | 1978-01-30 |
IE46409B1 (en) | 1983-06-01 |
FR2380782B1 (US07655688-20100202-C00010.png) | 1980-01-18 |
NL7801422A (nl) | 1978-08-24 |
IE780335L (en) | 1978-08-22 |
ATA124578A (de) | 1980-12-15 |
CH632164A5 (de) | 1982-09-30 |
CA1099633A (en) | 1981-04-21 |
LU79090A1 (fr) | 1979-05-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0602585B1 (de) | Dialyselösung für die Peritonealdialyse | |
DE2029455C3 (de) | Verfahren zur Herstellung eines neuen Prothrombinkomplexes | |
DE2807202A1 (de) | Stabile thymosinfraktion 5 und deren herstellung | |
DE3430809A1 (de) | Sucralfat-suspension | |
DE2219635C3 (de) | Insulinsalz-Protamin-Komplexe und Verfahren zu ihrer Herstellung | |
DE3021006A1 (de) | Neues oberflaechenaktives material, verfahren zur herstellung desselben und dieses material enthaltendes pharmazeutisches mittel gegen hyalin-membran-erkrankung | |
DE2725204A1 (de) | Immunitaets-stimulierendes medikament und verfahren zu seiner herstellung | |
DE2547105A1 (de) | N-acetyl-muramyl-l-alanyl-d-isoglutamin enthaltende oelfreie adjuvanzien | |
DE2433209A1 (de) | Hitzestabile plasmaproteinloesungen, verfahren zu ihrer herstellung und arzneipraeparate | |
DE2834702A1 (de) | Von mineralsalzen, insbesondere oxalaten, befreite heparinpraeparate, verfahren zu ihrer herstellung und ihre verwendung | |
DE3046565A1 (de) | Verfahren zur trennung von blutserumproteinen | |
DE2262427C3 (de) | Immunostimulierendes Mittel | |
DE2358123A1 (de) | Infusionsmaterial und verfahren zu seiner herstellung | |
DE1910715A1 (de) | Antimikrobielle Faktoren und deren Verwendung | |
DE69520278T2 (de) | Verwendung eines Disaccharids als Stabilisator für flüssige Proteinmischungen sowie ein Disaccharid enthaltende flüssige Proteinmischungen | |
DE2256215A1 (de) | Neue arzneimittel-zubereitung mit antidiabetischer wirkung | |
DE657129C (de) | Verfahren zur Herstellung von Loesungen oder Extrakten aus Bakterien, Pollen oder sonstigen pflanzlichen Zellen | |
DE1118792B (de) | Verfahren zur Herstellung von Blutplasmaersatzmitteln aus Kollagenabbauprodukten | |
AT367297B (de) | Verfahren zur herstellung eines serumeiweiss-pr[parates | |
AT200257B (US07655688-20100202-C00010.png) | ||
DE1617433C (de) | Verfahren zur Herstellung von 5,5 Diphenyl hydantoin Natrium Losungen fur Injektionszwecke | |
DE642980C (de) | Verfahren zur Herstellung von therapeutisch wirksamen Loesungen aus Bakterien | |
DE1001803C2 (de) | Verfahren zur Herstellung eines Arzneimittels mit antituberkuloeser Aktivitaet | |
AT83398B (de) | Verfahren zur Übertragung von sogenannten Immunstoffen von spezifischen Eiweißkörpern auf unspezifisches oder mit anders gearteten Immunstoffen beladenes Eiweiß. | |
DE472346C (de) | Verfahren zur Herstellung einer lange Zeit klar bleibenden, konzentrierten, intramuskulaer ohne Gewebereizung injizierbaren Calciumloesung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
OB | Request for examination as to novelty | ||
OC | Search report available | ||
8110 | Request for examination paragraph 44 | ||
8125 | Change of the main classification |
Ipc: A61K 37/24 |
|
8128 | New person/name/address of the agent |
Representative=s name: LEDERER, F., DIPL.-CHEM. DR., PAT.-ANW., 8000 MUEN |
|
D2 | Grant after examination | ||
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: F. HOFFMANN-LA ROCHE AG, BASEL, CH |
|
8328 | Change in the person/name/address of the agent |
Free format text: LEDERER, F., DIPL.-CHEM. DR., 8000 MUENCHEN RIEDERER FRHR. VON PAAR ZU SCHOENAU, A., DIPL.-ING., PAT.-ANWAELTE, 8300 LANDSHUT |
|
8339 | Ceased/non-payment of the annual fee |