DE2616479C2 - Substituierte Fluoracylresorcine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel und Kosmetika - Google Patents

Substituierte Fluoracylresorcine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel und Kosmetika

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Publication number
DE2616479C2
DE2616479C2 DE2616479A DE2616479A DE2616479C2 DE 2616479 C2 DE2616479 C2 DE 2616479C2 DE 2616479 A DE2616479 A DE 2616479A DE 2616479 A DE2616479 A DE 2616479A DE 2616479 C2 DE2616479 C2 DE 2616479C2
Authority
DE
Germany
Prior art keywords
dihydroxy
trifluoroacetophenone
group
general formula
yield
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2616479A
Other languages
German (de)
English (en)
Other versions
DE2616479A1 (de
Inventor
Karl-Richard Dr. 7950 Biberach Appel
Rolf Dipl.-Chem. Dr. Brickl
Hans Dipl.-Chem. Dr. Eberhardt
Uwe Dr. 7951 Ummendorf Lechner
Walter Dr. 7950 Biberach Merk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BRICKL ROLF DR 7951 WARTHAUSEN DE
Original Assignee
BRICKL ROLF DR 7951 WARTHAUSEN DE
Brickl Rolf Dr 7951 Warthausen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BRICKL ROLF DR 7951 WARTHAUSEN DE, Brickl Rolf Dr 7951 Warthausen filed Critical BRICKL ROLF DR 7951 WARTHAUSEN DE
Priority to DE2616479A priority Critical patent/DE2616479C2/de
Priority to GR53080A priority patent/GR62662B/el
Priority to NL7703133A priority patent/NL7703133A/xx
Priority to AT240777A priority patent/AT351510B/de
Priority to IL51865A priority patent/IL51865A/xx
Priority to ES457745A priority patent/ES457745A1/es
Priority to CH451377A priority patent/CH629742A5/de
Priority to LU77105A priority patent/LU77105A1/xx
Priority to PH19654A priority patent/PH16473A/en
Priority to PT66432A priority patent/PT66432B/pt
Priority to TR19916A priority patent/TR19916A/xx
Priority to NO771279A priority patent/NO147598C/no
Priority to BE176687A priority patent/BE853558A/xx
Priority to ZA00772233A priority patent/ZA772233B/xx
Priority to SE7704256A priority patent/SE7704256L/xx
Priority to IT48949/77A priority patent/IT1115953B/it
Priority to GB15351/77A priority patent/GB1566512A/en
Priority to JP4247577A priority patent/JPS52128340A/ja
Priority to CA276,129A priority patent/CA1101438A/en
Priority to DK164377A priority patent/DK164377A/da
Priority to FI771158A priority patent/FI69054C/fi
Priority to NZ183860A priority patent/NZ183860A/en
Priority to FR7711280A priority patent/FR2361329A1/fr
Priority to AU24287/77A priority patent/AU507258B2/en
Priority to IE781/77A priority patent/IE44820B1/en
Priority to ES463411A priority patent/ES463411A1/es
Priority to ES463410A priority patent/ES463410A1/es
Priority to ES463409A priority patent/ES463409A1/es
Priority to ES463407A priority patent/ES463407A1/es
Priority to ES463408A priority patent/ES463408A1/es
Priority to NO773721A priority patent/NO149092C/no
Publication of DE2616479A1 publication Critical patent/DE2616479A1/de
Priority to AT382878A priority patent/AT351514B/de
Priority to AT382478A priority patent/AT350527B/de
Priority to AT382578A priority patent/AT350522B/de
Priority to AT382778A priority patent/AT351513B/de
Priority to AT382678A priority patent/AT350528B/de
Priority to AT382378A priority patent/AT351512B/de
Priority to US06/021,777 priority patent/US4225619A/en
Priority to CH341081A priority patent/CH633509A5/de
Priority to CH340981A priority patent/CH636835A5/de
Priority to CH341281A priority patent/CH630881A5/de
Priority to CH340881A priority patent/CH630880A5/de
Priority to CH341181A priority patent/CH631958A5/de
Application granted granted Critical
Publication of DE2616479C2 publication Critical patent/DE2616479C2/de
Expired legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
    • A01N35/04—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aldehyde or keto groups, or thio analogues thereof, directly attached to an aromatic ring system, e.g. acetophenone; Derivatives thereof, e.g. acetals
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    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
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    • A01N37/10—Aromatic or araliphatic carboxylic acids, or thio analogues thereof; Derivatives thereof
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    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
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    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
    • A01N37/38—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
    • A01N37/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system having at least one carboxylic group or a thio analogue, or a derivative thereof, and one oxygen or sulfur atom attached to the same aromatic ring system
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    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N41/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07C317/00—Sulfones; Sulfoxides
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    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
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    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
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    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
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DE2616479A 1976-04-14 1976-04-14 Substituierte Fluoracylresorcine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel und Kosmetika Expired DE2616479C2 (de)

Priority Applications (43)

Application Number Priority Date Filing Date Title
DE2616479A DE2616479C2 (de) 1976-04-14 1976-04-14 Substituierte Fluoracylresorcine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel und Kosmetika
GR53080A GR62662B (en) 1976-04-14 1977-03-23 Novel substituted fluoracylresorcine and pharmaceutical means cosmetics and pesticides containing thereof
NL7703133A NL7703133A (nl) 1976-04-14 1977-03-23 Werkwijze ter bereiding van nieuwe gesubstitu- eerde fluoracylresorcinolen en van farmaceu- tische, cosmetische en pesticide preparaten, die deze fluoracylresorcinolen bevatten.
AT240777A AT351510B (de) 1976-04-14 1977-04-06 Verfahren zur herstellung neuer substituierter fluoracylresorcine
ES457745A ES457745A1 (es) 1976-04-14 1977-04-12 Procedimiento para la preparacion de nuevas fluoracil-resor-cinas sustituidas.
CH451377A CH629742A5 (de) 1976-04-14 1977-04-12 Verfahren zur herstellung neuer substituierter fluoracylresorcine.
LU77105A LU77105A1 (enExample) 1976-04-14 1977-04-12
IL51865A IL51865A (en) 1976-04-14 1977-04-12 4-(perfluoroalkanoyl)resorcin derivatives,their preparation and compositions containing them
PH19654A PH16473A (en) 1976-04-14 1977-04-13 Substituted fluoracyl resorcinols
TR19916A TR19916A (tr) 1976-04-14 1977-04-13 Yeni suebstituee edilmis fluorasilrezorsinler ve bunlari ihtiva eden pestisitler
NO771279A NO147598C (no) 1976-04-14 1977-04-13 Analogifremgangsmaate for fremstilling av nye fysiologisk aktive fluoracylresorcinoler
BE176687A BE853558A (fr) 1976-04-14 1977-04-13 Nouvelles fluoroacylresorcines substituees et medicaments, cosmetiques et pesticides les renfermant.
ZA00772233A ZA772233B (en) 1976-04-14 1977-04-13 Improvements relating to substituted fluoroacylresorcins
SE7704256A SE7704256L (sv) 1976-04-14 1977-04-13 Nya substituerade fluoracylresorcin for lekemedel, kosmetika och pesticider samt forfarande for framstellning derav
IT48949/77A IT1115953B (it) 1976-04-14 1977-04-13 Fluoroacil-resorcine sostituite dotate di attivita' antiparassitaria e procedimento per la loro produzione
GB15351/77A GB1566512A (en) 1976-04-14 1977-04-13 Fluoroacylresorcin derivatives
JP4247577A JPS52128340A (en) 1976-04-14 1977-04-13 Novel substituted fluoroacylresorcin* and pharmaceutical*cosmetic and herbicide containing these compounds
CA276,129A CA1101438A (en) 1976-04-14 1977-04-13 Substituted fluoroacylresorcins and drugs, cosmetics and pesticides containing them
DK164377A DK164377A (da) 1976-04-14 1977-04-13 Substituerede fluoracylresorciner fremgangsmade til deres fremstilling samt legemidler kosmetica og pesticider indeholdende disse forbindelser
FI771158A FI69054C (fi) 1976-04-14 1977-04-13 Foerfarande foer framstaellning av substituerade fluoracylresorsiner verksamma mot bakterier svampar cellkulturer och enzymer
PT66432A PT66432B (de) 1976-04-14 1977-04-13 Neue substituierte fluoracylresorcine und diese enthaltende arzneimittel kosmetika und pestizide
FR7711280A FR2361329A1 (fr) 1976-04-14 1977-04-14 Nouvelles fluoroacylresorcines substituees et medicaments, cosmetiques et pesticides les renfermant
NZ183860A NZ183860A (en) 1976-04-14 1977-04-14 Fluoroacylresorcin derivatives and pharmaceutical veterinary,herbicidal,and cosmetic compositions
AU24287/77A AU507258B2 (en) 1976-04-14 1977-04-14 Fluoroacacylresorcin derivatives
IE781/77A IE44820B1 (en) 1976-04-14 1977-04-14 Fluoroacylresorcin derivatives
ES463411A ES463411A1 (es) 1976-04-14 1977-10-20 Procedimiento para la preparacion de nuevas fluoracil-resor-cinas sustituidas.
ES463410A ES463410A1 (es) 1976-04-14 1977-10-20 Procedimiento para la preparacion de nuevas fluoracil-resor-cinas sustituidas.
ES463409A ES463409A1 (es) 1976-04-14 1977-10-20 Procedimiento para la preparacion de nuevas fluoracil-resor-cinas sustituidas.
ES463407A ES463407A1 (es) 1976-04-14 1977-10-20 Procedimiento para la preparacion de nuevas fluoracil-resor-cinas sustituidas.
ES463408A ES463408A1 (es) 1976-04-14 1977-10-20 Procedimiento para la preparacion de nuevas fluoracil-resor-cinas sustituidas.
NO773721A NO149092C (no) 1976-04-14 1977-10-31 Kosmetisk hud- og haarpleiemiddel
AT382578A AT350522B (de) 1976-04-14 1978-05-26 Verfahren zur herstellung neuer fluoracyl- resorcine
AT382478A AT350527B (de) 1976-04-14 1978-05-26 Verfahren zur herstellung neuer substituierter fluoracylresorcine
AT382878A AT351514B (de) 1976-04-14 1978-05-26 Verfahren zur herstellung neuer fluoracylresorcine
AT382778A AT351513B (de) 1976-04-14 1978-05-26 Verfahren zur herstellung neuer fluoracylresorcine
AT382678A AT350528B (de) 1976-04-14 1978-05-26 Verfahren zur herstellung neuer fluoracylresorcine
AT382378A AT351512B (de) 1976-04-14 1978-05-26 Verfahren zur herstellung neuer substituierter fluoracylresorcine
US06/021,777 US4225619A (en) 1976-04-14 1979-03-19 Substituted fluoracylresorcinols
CH341081A CH633509A5 (de) 1976-04-14 1981-05-25 Verfahren zur herstellung neuer substituierter fluoracylresorcine.
CH340981A CH636835A5 (de) 1976-04-14 1981-05-25 Verfahren zur herstellung neuer substituierter fluoracylresorcine.
CH341281A CH630881A5 (de) 1976-04-14 1981-05-25 Verfahren zur herstellung neuer substituierter fluoracylresorcine.
CH340881A CH630880A5 (de) 1976-04-14 1981-05-25 Verfahren zur herstellung neuer substituierter fluoracylresorcine.
CH341181A CH631958A5 (de) 1976-04-14 1981-05-25 Verfahren zur herstellung neuer substituierter fluoracylresorcine.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2616479A DE2616479C2 (de) 1976-04-14 1976-04-14 Substituierte Fluoracylresorcine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel und Kosmetika

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DE2616479A1 DE2616479A1 (de) 1977-11-03
DE2616479C2 true DE2616479C2 (de) 1986-12-04

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US (1) US4225619A (enExample)
JP (1) JPS52128340A (enExample)
AT (1) AT351510B (enExample)
AU (1) AU507258B2 (enExample)
BE (1) BE853558A (enExample)
CA (1) CA1101438A (enExample)
CH (6) CH629742A5 (enExample)
DE (1) DE2616479C2 (enExample)
DK (1) DK164377A (enExample)
ES (6) ES457745A1 (enExample)
FI (1) FI69054C (enExample)
FR (1) FR2361329A1 (enExample)
GB (1) GB1566512A (enExample)
GR (1) GR62662B (enExample)
IE (1) IE44820B1 (enExample)
IL (1) IL51865A (enExample)
IT (1) IT1115953B (enExample)
LU (1) LU77105A1 (enExample)
NL (1) NL7703133A (enExample)
NO (2) NO147598C (enExample)
NZ (1) NZ183860A (enExample)
PH (1) PH16473A (enExample)
PT (1) PT66432B (enExample)
SE (1) SE7704256L (enExample)
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ZA (1) ZA772233B (enExample)

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JPS56104835A (en) * 1980-01-23 1981-08-20 Shionogi & Co Ltd Novel synthesis of 2-haloacetylphenols
US4503256A (en) * 1981-07-02 1985-03-05 Noristan Limited Phlorophenone derivatives, processes for preparing such compounds, uses and pharmaceutical compositions of phlorophenone compounds
US4562292A (en) * 1983-08-18 1985-12-31 The Regents Of The University Of California Trifluoromethylketone sulfides and reversible enzyme inhibition therewith
IT1212907B (it) * 1983-12-21 1989-11-30 Romeo Aurelio Preparazione di fenoli alogenati
US5225607A (en) * 1985-08-09 1993-07-06 Imperial Chemical Industries Plc Insecticidal ethers
PT81492B (pt) * 1985-09-17 1988-03-03 Ciba Geigy Ag Processo para a preparacao de novos eteres de resorcina fluorados
GB2199825B (en) * 1987-01-08 1991-04-17 Ici Plc Insecticidal ethers
SK280617B6 (sk) * 1992-01-16 2000-05-16 Hoechst Aktiengesellschaft Arylcykloalkylové deriváty, spôsob ich prípravy, f
US5567850A (en) * 1994-11-08 1996-10-22 General Electric Company Method for making acyl substituted resorcinols
IL118657A0 (en) 1996-06-14 1996-10-16 Arad Dorit Inhibitors for picornavirus proteases
US5684035A (en) * 1996-07-17 1997-11-04 Kapadia; Govind J. Antimalarial agents
BR9803596A (pt) * 1997-09-23 2000-04-25 Pfizer Prod Inc Derivados do resorcinol.
IL122591A0 (en) 1997-12-14 1998-06-15 Arad Dorit Pharmaceutical compositions comprising cystein protease inhibitors
US6878381B2 (en) * 1999-03-22 2005-04-12 Pfizer, Inc Resorcinol composition
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JP4267920B2 (ja) * 2001-01-26 2009-05-27 中外製薬株式会社 代謝調節剤として有用なマロニル−ＣｏＡ脱炭酸酵素阻害剤
EP1372551B1 (en) 2001-03-08 2008-09-17 The Trustees Of The University Of Pennsylvania Facially amphiphilic polymers as anti-infective agents
WO2004082634A2 (en) 2003-03-17 2004-09-30 The Trustees Of The University Of Pennsylvania Facially amphiphilic polymers and oligomers and uses thereof
CA2554163A1 (en) 2004-01-23 2005-08-11 The Trustees Of The University Of Pennsylvania Facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers and uses thereof
EP1961727A1 (de) * 2007-02-26 2008-08-27 Bayer CropScience AG Verfahren zur Herstellung von 2,4-Dihydroxyphenyl-4-methoxybenzyl-ketonen
GB2511470B (en) 2012-04-25 2020-07-15 Univ Sussex Treatment of fungal infections using alternative oxidase inhibitors
GB201401117D0 (en) * 2014-01-23 2014-03-12 Univ Sussex The Antifungal composition
CN117466786A (zh) * 2023-12-25 2024-01-30 湖南一格制药有限公司 盐酸戊乙奎醚杂质及其制备方法

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JPS5242474A (en) * 1975-10-01 1977-04-02 Central Glass Co Ltd Press roll for granulation

Also Published As

Publication number Publication date
IE44820B1 (en) 1982-04-07
PT66432B (de) 1979-03-09
ATA240777A (de) 1979-01-15
US4225619A (en) 1980-09-30
IE44820L (en) 1977-10-14
FI69054C (fi) 1985-12-10
CH630881A5 (de) 1982-07-15
NO149092B (no) 1983-11-07
ES457745A1 (es) 1978-07-16
JPS6326095B2 (enExample) 1988-05-27
FR2361329A1 (fr) 1978-03-10
AU507258B2 (en) 1980-02-07
NO147598C (no) 1983-05-11
ES463410A1 (es) 1978-07-16
AT351510B (de) 1979-07-25
ES463409A1 (es) 1978-07-16
TR19916A (tr) 1980-04-28
FI771158A7 (enExample) 1977-10-15
ES463411A1 (es) 1978-07-16
SE7704256L (sv) 1977-11-25
IL51865A (en) 1980-11-30
NL7703133A (nl) 1977-10-18
DE2616479A1 (de) 1977-11-03
CH629742A5 (de) 1982-05-14
CH636835A5 (de) 1983-06-30
FR2361329B1 (enExample) 1980-12-19
NO147598B (no) 1983-01-31
ES463408A1 (es) 1978-07-16
NO771279L (no) 1977-10-17
NZ183860A (en) 1984-07-06
CH633509A5 (de) 1982-12-15
DK164377A (da) 1977-10-15
PH16473A (en) 1983-10-24
NO773721L (no) 1977-10-17
CH630880A5 (de) 1982-07-15
GB1566512A (en) 1980-04-30
ES463407A1 (es) 1978-07-16
FI69054B (fi) 1985-08-30
AU2428777A (en) 1978-10-19
CH631958A5 (de) 1982-09-15
LU77105A1 (enExample) 1979-01-18
GR62662B (en) 1979-05-17
ZA772233B (en) 1978-12-27
JPS52128340A (en) 1977-10-27
BE853558A (fr) 1977-10-13
IT1115953B (it) 1986-02-10
IL51865A0 (en) 1977-06-30
CA1101438A (en) 1981-05-19
NO149092C (no) 1984-02-15
PT66432A (de) 1977-05-01

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