DE1179200B - Verfahren zur Herstellung von N-Benzolsulfonyl-N'-methyl-cyclohexylharnstoffen - Google Patents

Verfahren zur Herstellung von N-Benzolsulfonyl-N'-methyl-cyclohexylharnstoffen

Info

Publication number
DE1179200B
DE1179200B DEF30394A DEF0030394A DE1179200B DE 1179200 B DE1179200 B DE 1179200B DE F30394 A DEF30394 A DE F30394A DE F0030394 A DEF0030394 A DE F0030394A DE 1179200 B DE1179200 B DE 1179200B
Authority
DE
Germany
Prior art keywords
benzenesulfonyl
methylcyclohexyl
substituted
ureas
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DEF30394A
Other languages
German (de)
English (en)
Inventor
Dr Helmut Weber
Dr Walter Aumueller
Dr Rudi Weyer
Dr Gerhard Korger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Priority to DEF30394A priority Critical patent/DE1179200B/de
Priority to CH1689464A priority patent/CH392498A/de
Priority to CH84061A priority patent/CH390907A/de
Priority to CH1689364A priority patent/CH392497A/de
Priority to AT72162A priority patent/AT226728B/de
Priority to GB3107/61A priority patent/GB935980A/en
Priority to FR850859A priority patent/FR1463758A/fr
Priority to BE599530A priority patent/BE599530A/fr
Priority to FR859855A priority patent/FR1101M/fr
Priority to FR859856A priority patent/FR1102M/fr
Priority to FR859854A priority patent/FR1100M/fr
Priority to FR859857A priority patent/FR1103M/fr
Priority to DEF37807A priority patent/DE1181208B/de
Priority claimed from DEF38828A external-priority patent/DE1185606B/de
Priority to GB34126/63A priority patent/GB1041783A/en
Priority to BR152525/63A priority patent/BR6352525D0/pt
Priority to FI1692/63A priority patent/FI41155B/fi
Priority to DK418063AA priority patent/DK118872B/da
Priority to NL297535A priority patent/NL128280C/xx
Priority to CH728167A priority patent/CH441280A/de
Priority to SE9938/63A priority patent/SE309589B/xx
Priority to CH728067A priority patent/CH441279A/de
Priority to SE4641/65A priority patent/SE310493B/xx
Priority to CH1123063A priority patent/CH440251A/de
Priority to CH727967A priority patent/CH441278A/de
Priority to BE637431D priority patent/BE637431A/xx
Publication of DE1179200B publication Critical patent/DE1179200B/de
Priority to DK605464AA priority patent/DK117143B/da
Priority to DK605564AA priority patent/DK117348B/da
Priority to DK605364AA priority patent/DK117347B/da
Priority to SE4642/65A priority patent/SE310494B/xx
Priority to SE4640/65A priority patent/SE310492B/xx
Priority to US518552A priority patent/US3483297A/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52Y being a hetero atom
    • C07C311/54Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
    • C07C311/57Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/59Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to carbon atoms of rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52Y being a hetero atom
    • C07C311/54Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
DEF30394A 1960-01-26 1960-01-26 Verfahren zur Herstellung von N-Benzolsulfonyl-N'-methyl-cyclohexylharnstoffen Pending DE1179200B (de)

Priority Applications (31)

Application Number Priority Date Filing Date Title
DEF30394A DE1179200B (de) 1960-01-26 1960-01-26 Verfahren zur Herstellung von N-Benzolsulfonyl-N'-methyl-cyclohexylharnstoffen
CH1689464A CH392498A (de) 1960-01-26 1961-01-24 Verfahren zur Herstellung von neuen Benzolsulfonyl-cyclohexyl-harnstoffen
CH84061A CH390907A (de) 1960-01-26 1961-01-24 Verfahren zur Herstellung von neuen Benzolsulfonylcyclohexylharnstoffen
CH1689364A CH392497A (de) 1960-01-26 1961-01-24 Verfahren zur Herstellung von neuen Benzolsulfonyl-cyclohexyl-harnstoffen
AT72162A AT226728B (de) 1960-01-26 1961-01-24 Verfahren zur Herstellung von neuen Benzolsulfonyl-cyclohexyl-harnstoffen
BE599530A BE599530A (fr) 1960-01-26 1961-01-26 Procédé de préparation de nouvelles benzène-sulfonyl-cyclohexyl-urées
FR850859A FR1463758A (fr) 1960-01-26 1961-01-26 Procédé de préparation de nouvelles benzène-sulfonyl-cyclohexyl-urées
GB3107/61A GB935980A (en) 1960-01-26 1961-01-26 Sulphonyl-ureas, processes for preparing them and preparations containing them
FR859855A FR1101M (fr) 1960-01-26 1961-04-25 Médicament hypoglycémiant contenant de la n-(4-méthyl-benzene-sulfonyl)-n'-(4'-méthylcyclohexy)-urée.
FR859856A FR1102M (fr) 1960-01-26 1961-04-25 Médicament hypoglycémiant a base de n-(4-méthoxy-benzene-sulfonyl)-n'-(2'-méthylcyclohexy)-urée.
FR859854A FR1100M (fr) 1960-01-26 1961-04-25 Médicament hypoglycémiant contenant de la n-(4-méthoxy-benzene-sulfonyl)-n'-(4'-méthylcyclohexy)-urée.
FR859857A FR1103M (fr) 1960-01-26 1962-04-25 Médicament hypoglycémiant a base de n-(4-méthyl-benzene-sulfonyl)-n'-(3'-méthylcyclohexy)-urée.
DEF37807A DE1181208B (de) 1960-01-26 1962-09-14 Verfahren zur Herstellung von N-Benzolsulfonyl-N'-cyclohexyl-harnstoffen
GB34126/63A GB1041783A (en) 1960-01-26 1963-08-28 New benzenesulphonyl-cyclohexyl ureas, preparations containing them and process for their manufacture
FI1692/63A FI41155B (US20080293856A1-20081127-C00150.png) 1960-01-26 1963-09-04
BR152525/63A BR6352525D0 (pt) 1960-01-26 1963-09-04 Processo para a preparacao de benzenos-sulfonil-ciclohexil-ureias
DK418063AA DK118872B (da) 1960-01-26 1963-09-04 Fremgangsmåde til fremstilling af benzensulfonylcyclohexyl-urinstoffer eller salte deraf.
NL297535A NL128280C (US20080293856A1-20081127-C00150.png) 1960-01-26 1963-09-05
CH728167A CH441280A (de) 1960-01-26 1963-09-11 Verfahren zur Herstellung von Benzolsulfonyl-cyclohexylharnstoffen
SE9938/63A SE309589B (US20080293856A1-20081127-C00150.png) 1960-01-26 1963-09-11
CH728067A CH441279A (de) 1960-01-26 1963-09-11 Verfahren zur Herstellung von Benzolsulfonyl-cyclohexylharnstoffen
SE4641/65A SE310493B (US20080293856A1-20081127-C00150.png) 1960-01-26 1963-09-11
CH1123063A CH440251A (de) 1960-01-26 1963-09-11 Verfahren zur Herstellung von Benzolsulfonyl-cyclohexylharnstoffen
CH727967A CH441278A (de) 1960-01-26 1963-09-11 Verfahren zur Herstellung von Benzolsulfonyl-cyclohexylharnstoffen
BE637431D BE637431A (US20080293856A1-20081127-C00150.png) 1960-01-26 1963-09-16
DK605364AA DK117347B (da) 1960-01-26 1964-12-09 Analogifremgangsmåde til fremstilling af benzensulfonylcyclohexylurinstoffer eller salte deraf.
DK605464AA DK117143B (da) 1960-01-26 1964-12-09 Analogifremgangsmåde til fremstilling af benzensulfonylcyclohexylurinstoffer eller salte deraf.
DK605564AA DK117348B (da) 1960-01-26 1964-12-09 Analogifremgangsmåde til fremstilling af benzensulfonylcyclohexylurinstoffer eller salte deraf.
SE4642/65A SE310494B (US20080293856A1-20081127-C00150.png) 1960-01-26 1965-04-09
SE4640/65A SE310492B (US20080293856A1-20081127-C00150.png) 1960-01-26 1965-04-09
US518552A US3483297A (en) 1960-01-26 1966-01-04 Treatment of diabetes with benzenesulfonylcyclohexyl ureas

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DEF30394A DE1179200B (de) 1960-01-26 1960-01-26 Verfahren zur Herstellung von N-Benzolsulfonyl-N'-methyl-cyclohexylharnstoffen
DEF37807A DE1181208B (de) 1960-01-26 1962-09-14 Verfahren zur Herstellung von N-Benzolsulfonyl-N'-cyclohexyl-harnstoffen
DEF38828A DE1185606B (de) 1963-01-23 1963-01-23 Verfahren zur Herstellung von N-Benzolsulfonyl-N'-cyclohexyl-harnstoffen

Publications (1)

Publication Number Publication Date
DE1179200B true DE1179200B (de) 1964-10-08

Family

ID=27210162

Family Applications (2)

Application Number Title Priority Date Filing Date
DEF30394A Pending DE1179200B (de) 1960-01-26 1960-01-26 Verfahren zur Herstellung von N-Benzolsulfonyl-N'-methyl-cyclohexylharnstoffen
DEF37807A Pending DE1181208B (de) 1960-01-26 1962-09-14 Verfahren zur Herstellung von N-Benzolsulfonyl-N'-cyclohexyl-harnstoffen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DEF37807A Pending DE1181208B (de) 1960-01-26 1962-09-14 Verfahren zur Herstellung von N-Benzolsulfonyl-N'-cyclohexyl-harnstoffen

Country Status (11)

Country Link
US (1) US3483297A (US20080293856A1-20081127-C00150.png)
BE (1) BE637431A (US20080293856A1-20081127-C00150.png)
BR (1) BR6352525D0 (US20080293856A1-20081127-C00150.png)
CH (7) CH390907A (US20080293856A1-20081127-C00150.png)
DE (2) DE1179200B (US20080293856A1-20081127-C00150.png)
DK (4) DK118872B (US20080293856A1-20081127-C00150.png)
FI (1) FI41155B (US20080293856A1-20081127-C00150.png)
FR (1) FR1463758A (US20080293856A1-20081127-C00150.png)
GB (2) GB935980A (US20080293856A1-20081127-C00150.png)
NL (1) NL128280C (US20080293856A1-20081127-C00150.png)
SE (4) SE309589B (US20080293856A1-20081127-C00150.png)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA915702A (en) * 1970-05-21 1972-11-28 Eric Lucien Preparation of 1-benzene-sulfonyl-3-hydrocarbylureas and derivatives
DK155051C (da) * 1980-05-06 1989-07-03 Pentapharm Ag Tripeptidderivater samt fremgangsmaade til kvantitativ analyse for proteolytiske enzymer under anvendelse deraf
US5110830A (en) * 1984-06-27 1992-05-05 Eli Lilly And Company Benzenesulfonamides treatment of tumors susceptible to
US5260338A (en) * 1984-06-27 1993-11-09 Eli Lilly And Company Anti-tumor method and compounds
DE10252650A1 (de) * 2002-11-11 2004-05-27 Grünenthal GmbH Cyclohexyl-Harnstoff-Derivate
CN110818647B (zh) * 2019-11-30 2022-07-22 中国石油大学(华东) 一种七元环脲类化合物的制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT196413B (de) * 1955-08-08 1958-03-25 Hoechst Ag Verfahren zur Herstellung von neuen Sulfonylharnstoffen
GB808073A (en) * 1955-05-28 1959-01-28 Hoechst Ag Manufacture of new sulphonyl-ureas
GB808071A (en) * 1955-05-28 1959-01-28 Hoechst Ag Manufacture of new sulphonyl-ureas

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2968158A (en) * 1955-08-08 1961-01-17 Upjohn Co New benzene sulfonyl ureas; composition and process for lowering blood sugar therewith
DE1135891B (de) * 1960-06-30 1962-09-06 Hoechst Ag Verfahren zur Herstellung von Benzolsulfonylharnstoffen
BE620550A (US20080293856A1-20081127-C00150.png) * 1961-07-21

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB808073A (en) * 1955-05-28 1959-01-28 Hoechst Ag Manufacture of new sulphonyl-ureas
GB808071A (en) * 1955-05-28 1959-01-28 Hoechst Ag Manufacture of new sulphonyl-ureas
AT196413B (de) * 1955-08-08 1958-03-25 Hoechst Ag Verfahren zur Herstellung von neuen Sulfonylharnstoffen

Also Published As

Publication number Publication date
SE309589B (US20080293856A1-20081127-C00150.png) 1969-03-31
DK117143B (da) 1970-03-23
CH440251A (de) 1967-07-31
SE310492B (US20080293856A1-20081127-C00150.png) 1969-05-05
CH390907A (de) 1965-04-30
GB1041783A (en) 1966-09-07
DK117348B (da) 1970-04-20
CH392497A (de) 1965-05-31
BR6352525D0 (pt) 1973-07-17
CH441279A (de) 1967-08-15
DK117347B (da) 1970-04-20
DE1181208B (de) 1964-11-12
DK118872B (da) 1970-10-19
BE637431A (US20080293856A1-20081127-C00150.png) 1964-03-16
SE310493B (US20080293856A1-20081127-C00150.png) 1969-05-05
SE310494B (US20080293856A1-20081127-C00150.png) 1969-05-05
FI41155B (US20080293856A1-20081127-C00150.png) 1969-06-02
US3483297A (en) 1969-12-09
CH441278A (de) 1967-08-15
FR1463758A (fr) 1966-07-22
GB935980A (en) 1963-09-04
CH441280A (de) 1967-08-15
CH392498A (de) 1965-05-31
NL128280C (US20080293856A1-20081127-C00150.png) 1970-03-16

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