DD292911A5 - Verfahren zur herstellung von pyrrolidinderivaten - Google Patents

Verfahren zur herstellung von pyrrolidinderivaten Download PDF

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Publication number
DD292911A5
DD292911A5 DD90338829A DD33882990A DD292911A5 DD 292911 A5 DD292911 A5 DD 292911A5 DD 90338829 A DD90338829 A DD 90338829A DD 33882990 A DD33882990 A DD 33882990A DD 292911 A5 DD292911 A5 DD 292911A5
Authority
DD
German Democratic Republic
Prior art keywords
formula
preparation
compound
dichloromethane
mixture
Prior art date
Application number
DD90338829A
Other languages
German (de)
English (en)
Inventor
Peter E Cross
Alexander R Mackenzie
Original Assignee
������@���Kk��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10653525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DD292911(A5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ������@���Kk�� filed Critical ������@���Kk��
Publication of DD292911A5 publication Critical patent/DD292911A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
DD90338829A 1989-03-17 1990-03-16 Verfahren zur herstellung von pyrrolidinderivaten DD292911A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898906166A GB8906166D0 (en) 1989-03-17 1989-03-17 Therapeutic agents

Publications (1)

Publication Number Publication Date
DD292911A5 true DD292911A5 (de) 1991-08-14

Family

ID=10653525

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90338829A DD292911A5 (de) 1989-03-17 1990-03-16 Verfahren zur herstellung von pyrrolidinderivaten

Country Status (37)

Country Link
US (1) US5096890B1 (sk)
EP (1) EP0388054B1 (sk)
JP (2) JPH0764809B2 (sk)
KR (2) KR920008166B1 (sk)
CN (1) CN1023007C (sk)
AT (1) ATE96783T1 (sk)
AU (1) AU614224B2 (sk)
BA (1) BA98300A (sk)
CA (1) CA2012295C (sk)
CL (1) CL2003002756A1 (sk)
CY (2) CY1812A (sk)
CZ (1) CZ280053B6 (sk)
DD (1) DD292911A5 (sk)
DE (2) DE122005000022I2 (sk)
DK (1) DK0388054T3 (sk)
EG (1) EG18951A (sk)
ES (1) ES2060020T3 (sk)
FI (1) FI95573C (sk)
GB (1) GB8906166D0 (sk)
HK (1) HK130294A (sk)
HU (2) HU217433B (sk)
IE (1) IE62515B1 (sk)
IL (1) IL93694A (sk)
LU (1) LU91161I2 (sk)
MX (1) MX9319890A (sk)
MY (1) MY105527A (sk)
NL (1) NL300191I2 (sk)
NO (2) NO176316C (sk)
NZ (1) NZ232958A (sk)
PL (1) PL164136B1 (sk)
PT (1) PT93443B (sk)
RU (2) RU1833374C (sk)
SG (1) SG143394G (sk)
SK (1) SK129590A3 (sk)
UA (1) UA18263A (sk)
YU (1) YU47587B (sk)
ZA (1) ZA901982B (sk)

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US5674891A (en) * 1994-07-27 1997-10-07 The Procter & Gamble Company Dihydrobenzothiophene compounds useful as anti-inflammatory agents
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US6693202B1 (en) 1999-02-16 2004-02-17 Theravance, Inc. Muscarinic receptor antagonists
IL141235A (en) * 2000-02-09 2012-04-30 Novartis Int Pharm Ltd Combined use of an alpha-adrenoceptor antagonist and a muscarinic antagonist in the preparation of a drug for the treatment of non-malignant prostatic hyperplasia
US6653339B2 (en) 2001-08-15 2003-11-25 Pfizer Inc. Method of treating irritable bowel syndrome
DE60230546D1 (de) * 2001-10-26 2009-02-05 Pharmacia & Upjohn Co Llc Quaternäre ammoniumverbindungen und deren verwendung als antimuscarinische wirkstoffe
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BR0215801A (pt) 2002-07-08 2005-05-10 Ranbaxy Lab Ltd Derivados de 3,6-dissubstituìdos azabiciclo [3.1.0] hexano úteis como antagonistas de receptores muscarìnicos
US7265147B2 (en) 2002-07-31 2007-09-04 Ranbaxy Laboratories Limited 3,6-disubstituted azabicyclo [3.1.0]hexane derivatives useful as muscarinic receptor antagonists
EP1545508A4 (en) 2002-08-09 2009-11-25 Ranbaxy Lab Ltd 3,6-DISUBSTITUTED AZABICYCLO ¬3.1.0 HEXANE DERIVATIVES AS USEFUL AS MUSCARINIC RECEPTOR AGONISTS
CN1688544A (zh) 2002-08-23 2005-10-26 兰贝克赛实验室有限公司 作为蕈毒碱受体拮抗剂的含氟代和磺酰氨基的3,6－二取代的氮杂双环(3.1.0)己烷衍生物
TW200412945A (en) * 2002-10-25 2004-08-01 Upjohn Co Quaternary ammonium compounds
TW200800953A (en) * 2002-10-30 2008-01-01 Theravance Inc Intermediates for preparing substituted 4-amino-1-(pyridylmethyl) piperidine
US7232835B2 (en) 2002-12-10 2007-06-19 Ranbaxy Laboratories Limited 3,6-Disubstituted azabicyclo derivatives as muscarinic receptor antagonists
US7465751B2 (en) 2002-12-23 2008-12-16 Ranbaxy Laboratories Limited 1-substituted-3-pyrrolidine derivatives as muscarinic receptor antagonists
ATE386738T1 (de) 2002-12-23 2008-03-15 Ranbaxy Lab Ltd Flavaxat-derivate als muscarin-rezeptor antagonisten
US7488748B2 (en) 2003-01-28 2009-02-10 Ranbaxy Laboratories Limited 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists
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DE60313898T2 (de) 2003-04-10 2008-01-17 Ranbaxy Laboratories, Ltd. Substituierte azabicyclo hexane derivate als muscarin rezeptor antagonisten
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EP1622606A1 (en) * 2003-04-15 2006-02-08 Pharmacia & Upjohn Company LLC Quaternary ammonium compounds and their use as antimuscarinic agents
WO2004091597A2 (en) * 2003-04-15 2004-10-28 Pharmacia & Upjohn Company Llc Method of treating irritable bowel syndrome (ibs)
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Also Published As

Publication number Publication date
PT93443A (pt) 1990-11-07
PT93443B (pt) 1996-02-29
CN1023007C (zh) 1993-12-08
IE62515B1 (en) 1995-02-08
KR900014367A (ko) 1990-10-23
AU614224B2 (en) 1991-08-22
JPH0764809B2 (ja) 1995-07-12
IL93694A (en) 1994-08-26
FI901333A0 (fi) 1990-03-16
DK0388054T3 (da) 1993-12-06
ZA901982B (en) 1991-10-30
UA18263A (uk) 1997-12-25
IL93694A0 (en) 1990-12-23
KR960015142B1 (ko) 1996-11-01
NZ232958A (en) 1992-05-26
RU2015965C1 (ru) 1994-07-15
CA2012295A1 (en) 1990-09-17
ATE96783T1 (de) 1993-11-15
NL300191I2 (nl) 2005-08-01
NO901241D0 (no) 1990-03-16
YU52790A (sh) 1992-07-20
HUT58313A (en) 1992-02-28
CA2012295C (en) 1996-11-12
HU217433B (hu) 2000-01-28
CY2005005I2 (el) 2010-07-28
MX9319890A (es) 1993-08-01
BA98300A (bs) 2001-09-14
EG18951A (en) 1994-03-30
PL164136B1 (pl) 1994-06-30
CY2005005I1 (el) 2010-07-28
AU5140290A (en) 1990-09-20
HU211640A9 (en) 1995-12-28
FI95573B (fi) 1995-11-15
CL2003002756A1 (es) 2005-02-11
FI95573C (fi) 1996-02-26
NO2005008I1 (en) 2005-04-11
NO176316C (no) 1995-03-15
LU91161I2 (fr) 2005-06-13
HK130294A (en) 1994-12-02
CN1045580A (zh) 1990-09-26
MY105527A (en) 1994-10-31
US5096890A (en) 1992-03-17
DE69004302T2 (de) 1994-02-24
DE69004302D1 (de) 1993-12-09
CY1812A (en) 1995-10-20
DE122005000022I2 (de) 2006-02-02
YU47587B (sh) 1995-10-24
SK278434B6 (en) 1997-05-07
DE122005000022I1 (de) 2005-08-04
EP0388054A1 (en) 1990-09-19
ES2060020T3 (es) 1994-11-16
US5096890B1 (en) 1995-03-28
JPH07149640A (ja) 1995-06-13
RU1833374C (ru) 1993-08-07
GB8906166D0 (en) 1989-05-04
EP0388054B1 (en) 1993-11-03
SK129590A3 (en) 1997-05-07
NO901241L (no) 1990-09-18
NL300191I1 (nl) 2005-07-01
CZ129590A3 (en) 1995-05-17
IE900955L (en) 1990-09-17
JPH02282360A (ja) 1990-11-19
CZ280053B6 (cs) 1995-10-18
KR920008166B1 (ko) 1992-09-24
SG143394G (en) 1995-01-13
NO2005008I2 (no) 2006-11-27
NO176316B (no) 1994-12-05
HU901580D0 (en) 1990-06-28

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