DD292911A5 - Verfahren zur herstellung von pyrrolidinderivaten - Google Patents

Verfahren zur herstellung von pyrrolidinderivaten Download PDF

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Publication number
DD292911A5
DD292911A5 DD90338829A DD33882990A DD292911A5 DD 292911 A5 DD292911 A5 DD 292911A5 DD 90338829 A DD90338829 A DD 90338829A DD 33882990 A DD33882990 A DD 33882990A DD 292911 A5 DD292911 A5 DD 292911A5
Authority
DD
German Democratic Republic
Prior art keywords
formula
preparation
compound
dichloromethane
mixture
Prior art date
Application number
DD90338829A
Other languages
German (de)
English (en)
Inventor
Peter E Cross
Alexander R Mackenzie
Original Assignee
������@���Kk��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10653525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DD292911(A5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ������@���Kk�� filed Critical ������@���Kk��
Publication of DD292911A5 publication Critical patent/DD292911A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
DD90338829A 1989-03-17 1990-03-16 Verfahren zur herstellung von pyrrolidinderivaten DD292911A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898906166A GB8906166D0 (en) 1989-03-17 1989-03-17 Therapeutic agents

Publications (1)

Publication Number Publication Date
DD292911A5 true DD292911A5 (de) 1991-08-14

Family

ID=10653525

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90338829A DD292911A5 (de) 1989-03-17 1990-03-16 Verfahren zur herstellung von pyrrolidinderivaten

Country Status (37)

Country Link
US (1) US5096890B1 (sk)
EP (1) EP0388054B1 (sk)
JP (2) JPH0764809B2 (sk)
KR (2) KR920008166B1 (sk)
CN (1) CN1023007C (sk)
AT (1) ATE96783T1 (sk)
AU (1) AU614224B2 (sk)
BA (1) BA98300A (sk)
CA (1) CA2012295C (sk)
CL (1) CL2003002756A1 (sk)
CY (2) CY1812A (sk)
CZ (1) CZ280053B6 (sk)
DD (1) DD292911A5 (sk)
DE (2) DE122005000022I2 (sk)
DK (1) DK0388054T3 (sk)
EG (1) EG18951A (sk)
ES (1) ES2060020T3 (sk)
FI (1) FI95573C (sk)
GB (1) GB8906166D0 (sk)
HK (1) HK130294A (sk)
HU (2) HU217433B (sk)
IE (1) IE62515B1 (sk)
IL (1) IL93694A (sk)
LU (1) LU91161I2 (sk)
MX (1) MX9319890A (sk)
MY (1) MY105527A (sk)
NL (1) NL300191I2 (sk)
NO (2) NO176316C (sk)
NZ (1) NZ232958A (sk)
PL (1) PL164136B1 (sk)
PT (1) PT93443B (sk)
RU (2) RU1833374C (sk)
SG (1) SG143394G (sk)
SK (1) SK129590A3 (sk)
UA (1) UA18263A (sk)
YU (1) YU47587B (sk)
ZA (1) ZA901982B (sk)

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US6693202B1 (en) 1999-02-16 2004-02-17 Theravance, Inc. Muscarinic receptor antagonists
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US6653339B2 (en) 2001-08-15 2003-11-25 Pfizer Inc. Method of treating irritable bowel syndrome
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BR0215801A (pt) 2002-07-08 2005-05-10 Ranbaxy Lab Ltd Derivados de 3,6-dissubstituìdos azabiciclo [3.1.0] hexano úteis como antagonistas de receptores muscarìnicos
US7265147B2 (en) 2002-07-31 2007-09-04 Ranbaxy Laboratories Limited 3,6-disubstituted azabicyclo [3.1.0]hexane derivatives useful as muscarinic receptor antagonists
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CN1688544A (zh) 2002-08-23 2005-10-26 兰贝克赛实验室有限公司 作为蕈毒碱受体拮抗剂的含氟代和磺酰氨基的3,6-二取代的氮杂双环(3.1.0)己烷衍生物
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US7232835B2 (en) 2002-12-10 2007-06-19 Ranbaxy Laboratories Limited 3,6-Disubstituted azabicyclo derivatives as muscarinic receptor antagonists
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ATE386738T1 (de) 2002-12-23 2008-03-15 Ranbaxy Lab Ltd Flavaxat-derivate als muscarin-rezeptor antagonisten
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DE60313898T2 (de) 2003-04-10 2008-01-17 Ranbaxy Laboratories, Ltd. Substituierte azabicyclo hexane derivate als muscarin rezeptor antagonisten
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EP1622606A1 (en) * 2003-04-15 2006-02-08 Pharmacia & Upjohn Company LLC Quaternary ammonium compounds and their use as antimuscarinic agents
WO2004091597A2 (en) * 2003-04-15 2004-10-28 Pharmacia & Upjohn Company Llc Method of treating irritable bowel syndrome (ibs)
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Also Published As

Publication number Publication date
PT93443A (pt) 1990-11-07
PT93443B (pt) 1996-02-29
CN1023007C (zh) 1993-12-08
IE62515B1 (en) 1995-02-08
KR900014367A (ko) 1990-10-23
AU614224B2 (en) 1991-08-22
JPH0764809B2 (ja) 1995-07-12
IL93694A (en) 1994-08-26
FI901333A0 (fi) 1990-03-16
DK0388054T3 (da) 1993-12-06
ZA901982B (en) 1991-10-30
UA18263A (uk) 1997-12-25
IL93694A0 (en) 1990-12-23
KR960015142B1 (ko) 1996-11-01
NZ232958A (en) 1992-05-26
RU2015965C1 (ru) 1994-07-15
CA2012295A1 (en) 1990-09-17
ATE96783T1 (de) 1993-11-15
NL300191I2 (nl) 2005-08-01
NO901241D0 (no) 1990-03-16
YU52790A (sh) 1992-07-20
HUT58313A (en) 1992-02-28
CA2012295C (en) 1996-11-12
HU217433B (hu) 2000-01-28
CY2005005I2 (el) 2010-07-28
MX9319890A (es) 1993-08-01
BA98300A (bs) 2001-09-14
EG18951A (en) 1994-03-30
PL164136B1 (pl) 1994-06-30
CY2005005I1 (el) 2010-07-28
AU5140290A (en) 1990-09-20
HU211640A9 (en) 1995-12-28
FI95573B (fi) 1995-11-15
CL2003002756A1 (es) 2005-02-11
FI95573C (fi) 1996-02-26
NO2005008I1 (en) 2005-04-11
NO176316C (no) 1995-03-15
LU91161I2 (fr) 2005-06-13
HK130294A (en) 1994-12-02
CN1045580A (zh) 1990-09-26
MY105527A (en) 1994-10-31
US5096890A (en) 1992-03-17
DE69004302T2 (de) 1994-02-24
DE69004302D1 (de) 1993-12-09
CY1812A (en) 1995-10-20
DE122005000022I2 (de) 2006-02-02
YU47587B (sh) 1995-10-24
SK278434B6 (en) 1997-05-07
DE122005000022I1 (de) 2005-08-04
EP0388054A1 (en) 1990-09-19
ES2060020T3 (es) 1994-11-16
US5096890B1 (en) 1995-03-28
JPH07149640A (ja) 1995-06-13
RU1833374C (ru) 1993-08-07
GB8906166D0 (en) 1989-05-04
EP0388054B1 (en) 1993-11-03
SK129590A3 (en) 1997-05-07
NO901241L (no) 1990-09-18
NL300191I1 (nl) 2005-07-01
CZ129590A3 (en) 1995-05-17
IE900955L (en) 1990-09-17
JPH02282360A (ja) 1990-11-19
CZ280053B6 (cs) 1995-10-18
KR920008166B1 (ko) 1992-09-24
SG143394G (en) 1995-01-13
NO2005008I2 (no) 2006-11-27
NO176316B (no) 1994-12-05
HU901580D0 (en) 1990-06-28

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