UA18263A - Спосіб одержаhhя похідhих пірролідіhу - Google Patents

Спосіб одержаhhя похідhих пірролідіhу

Info

Publication number
UA18263A
UA18263A UA4743599A UA4743599A UA18263A UA 18263 A UA18263 A UA 18263A UA 4743599 A UA4743599 A UA 4743599A UA 4743599 A UA4743599 A UA 4743599A UA 18263 A UA18263 A UA 18263A
Authority
UA
Ukraine
Prior art keywords
pyrrolidine
preparation
derivatives
muscarine
cardioreceptors
Prior art date
Application number
UA4743599A
Other languages
English (en)
Russian (ru)
Inventor
Едвард Кросс Пітер
Едвард Кросс Питер
Родерік Маккензі Александр
Original Assignee
Пфайзер, Інк.
Пфайзер, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10653525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA18263(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Пфайзер, Інк., Пфайзер, Инк. filed Critical Пфайзер, Інк.
Publication of UA18263A publication Critical patent/UA18263A/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)

Abstract

Метою винаходу є спосіб одержання нових похідних піролідіну, що мають цінну фармакологічну властивість. Ця властивість виявляється в селективності по відношенню мускаринових рецепторів гладких м'язів над мускариновими кардіорецепторами без якої-небудь значної антигістамінної активності.
UA4743599A 1989-03-17 1990-03-16 Спосіб одержаhhя похідhих пірролідіhу UA18263A (uk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898906166A GB8906166D0 (en) 1989-03-17 1989-03-17 Therapeutic agents

Publications (1)

Publication Number Publication Date
UA18263A true UA18263A (uk) 1997-12-25

Family

ID=10653525

Family Applications (1)

Application Number Title Priority Date Filing Date
UA4743599A UA18263A (uk) 1989-03-17 1990-03-16 Спосіб одержаhhя похідhих пірролідіhу

Country Status (37)

Country Link
US (1) US5096890B1 (uk)
EP (1) EP0388054B1 (uk)
JP (2) JPH0764809B2 (uk)
KR (2) KR920008166B1 (uk)
CN (1) CN1023007C (uk)
AT (1) ATE96783T1 (uk)
AU (1) AU614224B2 (uk)
BA (1) BA98300A (uk)
CA (1) CA2012295C (uk)
CL (1) CL2003002756A1 (uk)
CY (2) CY1812A (uk)
CZ (1) CZ280053B6 (uk)
DD (1) DD292911A5 (uk)
DE (2) DE122005000022I2 (uk)
DK (1) DK0388054T3 (uk)
EG (1) EG18951A (uk)
ES (1) ES2060020T3 (uk)
FI (1) FI95573C (uk)
GB (1) GB8906166D0 (uk)
HK (1) HK130294A (uk)
HU (2) HU217433B (uk)
IE (1) IE62515B1 (uk)
IL (1) IL93694A (uk)
LU (1) LU91161I2 (uk)
MX (1) MX9319890A (uk)
MY (1) MY105527A (uk)
NL (1) NL300191I2 (uk)
NO (2) NO176316C (uk)
NZ (1) NZ232958A (uk)
PL (1) PL164136B1 (uk)
PT (1) PT93443B (uk)
RU (2) RU1833374C (uk)
SG (1) SG143394G (uk)
SK (1) SK129590A3 (uk)
UA (1) UA18263A (uk)
YU (1) YU47587B (uk)
ZA (1) ZA901982B (uk)

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US5672620A (en) * 1996-02-01 1997-09-30 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
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DE69720518T2 (de) * 1996-12-02 2004-02-26 Kyorin Pharmaceutical Co., Ltd. Neue derivate von n-substituierten pyrrolidin derivaten und deren herstellungsverfahren
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US6693202B1 (en) 1999-02-16 2004-02-17 Theravance, Inc. Muscarinic receptor antagonists
IL141235A (en) * 2000-02-09 2012-04-30 Novartis Int Pharm Ltd Combined use of an alpha-adrenoceptor antagonist and a muscarinic antagonist in the preparation of a drug for the treatment of non-malignant prostatic hyperplasia
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Also Published As

Publication number Publication date
US5096890B1 (en) 1995-03-28
CA2012295C (en) 1996-11-12
PL164136B1 (pl) 1994-06-30
CY2005005I2 (el) 2010-07-28
CZ129590A3 (en) 1995-05-17
DD292911A5 (de) 1991-08-14
PT93443B (pt) 1996-02-29
KR960015142B1 (ko) 1996-11-01
IE62515B1 (en) 1995-02-08
NO176316B (no) 1994-12-05
NL300191I1 (nl) 2005-07-01
CY1812A (en) 1995-10-20
NO2005008I2 (no) 2006-11-27
HUT58313A (en) 1992-02-28
DK0388054T3 (da) 1993-12-06
MX9319890A (es) 1993-08-01
RU1833374C (ru) 1993-08-07
GB8906166D0 (en) 1989-05-04
FI95573B (fi) 1995-11-15
SG143394G (en) 1995-01-13
FI901333A0 (fi) 1990-03-16
AU614224B2 (en) 1991-08-22
NO901241L (no) 1990-09-18
FI95573C (fi) 1996-02-26
JPH0764809B2 (ja) 1995-07-12
CY2005005I1 (el) 2010-07-28
CA2012295A1 (en) 1990-09-17
CL2003002756A1 (es) 2005-02-11
KR900014367A (ko) 1990-10-23
ATE96783T1 (de) 1993-11-15
CN1045580A (zh) 1990-09-26
DE122005000022I1 (de) 2005-08-04
AU5140290A (en) 1990-09-20
LU91161I2 (fr) 2005-06-13
JPH07149640A (ja) 1995-06-13
IL93694A (en) 1994-08-26
CZ280053B6 (cs) 1995-10-18
MY105527A (en) 1994-10-31
US5096890A (en) 1992-03-17
SK278434B6 (en) 1997-05-07
PT93443A (pt) 1990-11-07
HU217433B (hu) 2000-01-28
BA98300A (bs) 2001-09-14
SK129590A3 (en) 1997-05-07
YU52790A (sh) 1992-07-20
RU2015965C1 (ru) 1994-07-15
EP0388054B1 (en) 1993-11-03
HK130294A (en) 1994-12-02
NO2005008I1 (en) 2005-04-11
IL93694A0 (en) 1990-12-23
HU901580D0 (en) 1990-06-28
DE122005000022I2 (de) 2006-02-02
NO901241D0 (no) 1990-03-16
EG18951A (en) 1994-03-30
NZ232958A (en) 1992-05-26
JPH02282360A (ja) 1990-11-19
EP0388054A1 (en) 1990-09-19
ES2060020T3 (es) 1994-11-16
CN1023007C (zh) 1993-12-08
NO176316C (no) 1995-03-15
DE69004302T2 (de) 1994-02-24
HU211640A9 (en) 1995-12-28
DE69004302D1 (de) 1993-12-09
KR920008166B1 (ko) 1992-09-24
IE900955L (en) 1990-09-17
ZA901982B (en) 1991-10-30
YU47587B (sh) 1995-10-24
NL300191I2 (nl) 2005-08-01

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