DD139854A5 - Verfahren zur herstellung neuer kondensierter pyrimidin-derivate - Google Patents

Verfahren zur herstellung neuer kondensierter pyrimidin-derivate Download PDF

Info

Publication number
DD139854A5
DD139854A5 DD78209808A DD20980878A DD139854A5 DD 139854 A5 DD139854 A5 DD 139854A5 DD 78209808 A DD78209808 A DD 78209808A DD 20980878 A DD20980878 A DD 20980878A DD 139854 A5 DD139854 A5 DD 139854A5
Authority
DD
German Democratic Republic
Prior art keywords
general formula
group
compounds
item
compound
Prior art date
Application number
DD78209808A
Other languages
German (de)
English (en)
Inventor
Istvan Hermecz
Zoltan Meszaros
Tibor Breining
Sandor Virag
Lelle Vasvari
Agnes Horvath
Gabor Nagy
Attila Mandi
Tamas Szuecs
Istvan Bitter
Gyula Sebestyen
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of DD139854A5 publication Critical patent/DD139854A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DD78209808A 1977-12-29 1978-12-15 Verfahren zur herstellung neuer kondensierter pyrimidin-derivate DD139854A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77CI1794A HU178496B (en) 1977-12-29 1977-12-29 Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity

Publications (1)

Publication Number Publication Date
DD139854A5 true DD139854A5 (de) 1980-01-23

Family

ID=10994683

Family Applications (1)

Application Number Title Priority Date Filing Date
DD78209808A DD139854A5 (de) 1977-12-29 1978-12-15 Verfahren zur herstellung neuer kondensierter pyrimidin-derivate

Country Status (29)

Country Link
US (2) US4234586A (ru)
JP (1) JPS5495598A (ru)
AR (3) AR222985A1 (ru)
AT (1) AT375936B (ru)
AU (1) AU520428B2 (ru)
BE (1) BE873194A (ru)
CA (1) CA1130284A (ru)
CH (1) CH642078A5 (ru)
CS (1) CS244654B2 (ru)
DD (1) DD139854A5 (ru)
DE (1) DE2854115A1 (ru)
DK (1) DK157022C (ru)
ES (7) ES476442A1 (ru)
FI (1) FI66614C (ru)
FR (1) FR2413389A1 (ru)
GB (1) GB2011898B (ru)
GR (1) GR68357B (ru)
HU (1) HU178496B (ru)
IL (1) IL56078A (ru)
IT (1) IT1203210B (ru)
LU (1) LU80601A1 (ru)
NL (1) NL7812547A (ru)
NO (1) NO151287C (ru)
PL (5) PL119641B1 (ru)
PT (1) PT68935A (ru)
SE (1) SE438675B (ru)
SU (2) SU999972A3 (ru)
YU (3) YU42093B (ru)
ZA (1) ZA787385B (ru)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178496B (en) * 1977-12-29 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity
US4482557A (en) * 1979-05-11 1984-11-13 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 3-Substituted-2-oxo-tetrahydro-pyrrol[1,2-a]pyrimidines having digitalis-like activity
HU178453B (en) * 1979-05-11 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-hydrazino-4-oxo-6,7,8,9-tetrahydro-4h-p-pyrido-square bracket-1,2-a-square bracket closed-pyrimidine derivatives
HU178452B (en) * 1979-05-11 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 9-substituted amino-4-oxo-6,7-dihydro-4h-pyrido/1,2-a/pyrimidine derivatives
HU176942B (hu) * 1979-05-11 1981-06-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija 2,3- i 3,4-dvuzamehhjonnykh tetragidro-pirrolo!1,2-a!-pirimidinov
HU179443B (en) * 1979-05-11 1982-10-28 Chinoin Gyogyszer Es Vegyeszet Process for producing substituted geminal dihalogeno-derivatives of pyrido-square bracket-1,2-a-square closed-pyrimidines,pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines and pyrimido-square bracket-1,2,-a-square bracket closed-asepines
AT381093B (de) * 1980-06-24 1986-08-25 Chinoin Gyogyszer Es Vegyeszet Verfahren zur herstellung neuer 6-hydrazono-pyrido(2,1-b)chinazolin-11-on-deriv te, von deren salzen sowie von deren stereomeren
HU183173B (en) * 1980-06-24 1984-04-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 6-hydrazono-pyrido-aracket-2,1-b-bracket closed-quinazolin-11-ones
HU183408B (en) 1981-04-28 1984-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing oral ratard pharmaceutical compositions
US4395549A (en) * 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
US5344933A (en) * 1991-09-11 1994-09-06 Fuji Photo Film Co., Ltd. Pyrrole ring-or condensed pyrrole ring-containing azomethine dye
EP1790649A1 (en) * 2005-11-21 2007-05-30 Sanofi-Aventis Substituted bicyclic pyrimidone derivatives
EP2138488A1 (en) 2008-06-26 2009-12-30 sanofi-aventis 4-(pyridin-4-yl)-1H-[1,3,5]triazin-2-one derivatives as GSK3-beta inhibitors for the treatment of neurodegenerative diseases
EP2138494A1 (en) 2008-06-26 2009-12-30 Sanofi-Aventis Substituted alkyl pyrimidin-4-one derivatives
EP2138498A1 (en) 2008-06-26 2009-12-30 sanofi-aventis Substituted tricyclic derivatives against neurodegenerative diseases
EP2138485A1 (en) 2008-06-26 2009-12-30 sanofi-aventis Substituted N-Oxide pyrazine derivatives
EP2138495A1 (en) 2008-06-26 2009-12-30 sanofi-aventis Substituted pyrimido[2,1-a]isoquinolin-4-one derivatives
EP2138492A1 (en) * 2008-06-26 2009-12-30 Sanofi-Aventis Substituted pyrimidin-4-one derivatives
EP2138493A1 (en) 2008-06-26 2009-12-30 Sanofi-Aventis Substituted pyrimidone derivatives

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2786056A (en) * 1954-05-03 1957-03-19 Merck & Co Inc Acylamido-hydroxy pteridines and preparation thereof
US2894031A (en) * 1958-09-16 1959-07-07 Grace W R & Co Process for cyclohexanone hydrazone hydrate
US3140315A (en) * 1959-02-18 1964-07-07 Bayer Ag Alkyl-substituted hydrazines and hydrazones and process for preparation thereof
FR1255365A (fr) * 1959-12-22 1961-03-10 Cfmc Nouveaux colorants basiques, leur procédé de préparation et leurs applications
US3141043A (en) * 1961-03-24 1964-07-14 Purdue Research Foundation Cyclopentadienylimines, process for their production and condensation products thereof
CH441366A (de) * 1961-06-09 1967-08-15 Hoffmann La Roche Verfahren zur Herstellung von substituierten Hydrazinverbindungen
US3417082A (en) * 1965-08-16 1968-12-17 Polaroid Corp Novel chemical compounds and syntheses
AT286990B (de) * 1966-11-02 1971-01-11 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von neuen Homopyrimidazol-Derivaten sowie von deren Salzen
HU168014B (ru) * 1973-03-30 1976-02-28
US4024132A (en) * 1973-09-07 1977-05-17 Ciba-Geigy Corporation Azomethine pigments
HU174693B (hu) * 1976-02-12 1980-03-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija kondensirovannykh proizvodnykh pirimidina
HU178496B (en) * 1977-12-29 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity

Also Published As

Publication number Publication date
ATA873678A (de) 1984-02-15
PL212212A1 (ru) 1980-02-25
AR227882A1 (es) 1982-12-30
CA1130284A (en) 1982-08-24
ES481746A1 (es) 1980-07-01
DK157022C (da) 1990-04-02
FR2413389B1 (ru) 1982-03-26
SE7813226L (sv) 1979-06-30
YU279582A (en) 1983-10-31
ES481749A1 (es) 1980-07-01
PT68935A (en) 1979-01-01
FI784013A (fi) 1979-06-30
SE438675B (sv) 1985-04-29
YU42093B (en) 1988-04-30
DE2854115C2 (ru) 1988-07-28
CS909178A2 (en) 1985-08-15
FI66614B (fi) 1984-07-31
BE873194A (fr) 1979-04-17
NO151287C (no) 1985-03-13
CH642078A5 (de) 1984-03-30
AT375936B (de) 1984-09-25
ES481747A1 (es) 1980-07-01
ZA787385B (en) 1980-02-27
PL122965B1 (en) 1982-09-30
NO151287B (no) 1984-12-03
ES481744A1 (es) 1980-06-16
SU999972A3 (ru) 1983-02-23
ES481748A1 (es) 1980-07-01
SU978730A3 (ru) 1982-11-30
US4461769A (en) 1984-07-24
JPH0146514B2 (ru) 1989-10-09
LU80601A1 (de) 1979-03-22
AR222985A1 (es) 1981-07-15
YU41538B (en) 1987-08-31
PL119520B1 (en) 1982-01-30
ES481745A1 (es) 1980-07-01
GB2011898A (en) 1979-07-18
IL56078A0 (en) 1979-01-31
FI66614C (fi) 1984-11-12
AU520428B2 (en) 1982-01-28
FR2413389A1 (fr) 1979-07-27
CS244654B2 (en) 1986-08-14
IT1203210B (it) 1989-02-15
YU296478A (en) 1983-10-31
HU178496B (en) 1982-05-28
YU42062B (en) 1988-04-30
AR228949A1 (es) 1983-05-13
JPS5495598A (en) 1979-07-28
YU279682A (en) 1983-10-31
GB2011898B (en) 1982-04-28
NO784393L (no) 1979-07-02
NL7812547A (nl) 1979-07-03
ES476442A1 (es) 1979-11-16
IT7869933A0 (it) 1978-12-22
PL119641B1 (en) 1982-01-30
DE2854115A1 (de) 1979-07-12
AU4262778A (en) 1979-07-05
PL119501B1 (en) 1982-01-30
US4234586A (en) 1980-11-18
GR68357B (ru) 1981-12-23
DK157022B (da) 1989-10-30
PL125321B1 (en) 1983-04-30
IL56078A (en) 1982-11-30
DK585578A (da) 1979-06-30

Similar Documents

Publication Publication Date Title
DD139854A5 (de) Verfahren zur herstellung neuer kondensierter pyrimidin-derivate
DE68902358T2 (de) Aromatische und heterocyclische carboxamide als antineoplastische mittel.
DE3614132A1 (de) 1,3-dihydro-2h-imidazo(4,5-b)chinolin-2-one, verfahren zu deren herstellung und diese verbindungen enthaltende, pharmazeutische mittel
DD272649A5 (de) Neue tricyclische benzimidazole, verfahren zu ihrer herstellung und verwendung als arzneimittel
DE69004256T2 (de) Dihydropyrimidin-antiallergie-mittel.
EP0266558A2 (de) 5-Alkylbenzimidazole, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
CH654306A5 (de) Substituierte 1h-pyrazolo-(1,5-a)-pyrimidine.
EP0271040A2 (de) Neue Pyrrolobenzimidazole, Verfahren zu ihrer Herstellung, sowie Arzneimittel
DE3533331A1 (de) Pyridothiazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DD239794A5 (de) Verfahren zur herstellung von 4-alkoxy-pyrido(2,3-d)-pyrimidin-derivaten
DE2142527A1 (de) Neue Tetrazoldenvate und Verfahren zu deren Herstellung
DE4027592A1 (de) Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
EP0576906A1 (de) Neue Thienothiazinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Antiinflammatorium und Analgeticum
CH631973A5 (de) Verfahren zur herstellung von benzimidazolderivaten.
DE2854112A1 (de) Neue pyrido-pyrimidine, verfahren zu ihrer herstellung und diese verbindungen enthaltenden arzneimittel
EP2007773B1 (de) Thiazolyl-dihydro-indazole
CH644384A5 (de) Imidazo(2',1':2,3)thiazolo(5,4-c)pyridine.
DD150604A5 (de) Verfahren zur herstellung von 9-amino-6,7-dihydro-4h-pyrido(1,2-a)pyrimidin-4-on-derivaten
EP0180833A1 (de) 4-Oxo-pyrido[2,3]pyrimidin-Derivate, Verfahren zur deren Herstellung und diese ethaltende Arzneimittel
DD272081A5 (de) Verfahren zur herstellung neuer pyrrolo-benzinmidazolen
AT376980B (de) Verfahren zur herstellung neuer pyrido(1,2-a)pyrimidin-derivate, von deren pharmazeutisch akzeptablen salzen sowie deren solvaten, stereoisomeren und tautomeren
WO1997027192A1 (de) 3-methylimidazopyridine
AT376981B (de) Verfahren zur herstellung neuer pyrido-(1,2-a) pyrimidin-derivate, von deren pharmazeutisch akzeptablen salzen sowie deren solvaten, stereoisomeren und tautomeren
CH634069A5 (en) Process for preparing novel 7-substituted 7H-pyrrolo[3,2-f]quinazoline-1,3-diamines
CH655115A5 (de) Substituierte aethenylderivate von 1h-pyrazolo-(1,5-a)-pyrimidin und verfahren zur herstellung derselben.

Legal Events

Date Code Title Description
VZ Disclaimer of patent (art. 11 and 12 extension act)