CY1833A - Therapeutic nucleosides - Google Patents

Therapeutic nucleosides

Info

Publication number
CY1833A
CY1833A CY183395A CY183395A CY1833A CY 1833 A CY1833 A CY 1833A CY 183395 A CY183395 A CY 183395A CY 183395 A CY183395 A CY 183395A CY 1833 A CY1833 A CY 1833A
Authority
CY
Cyprus
Prior art keywords
therapeutic nucleosides
nucleosides
therapeutic
Prior art date
Application number
CY183395A
Other languages
English (en)
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26292613&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1833(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB878719367A external-priority patent/GB8719367D0/en
Priority claimed from GB878725939A external-priority patent/GB8725939D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of CY1833A publication Critical patent/CY1833A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
CY183395A 1987-08-15 1995-12-01 Therapeutic nucleosides CY1833A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878719367A GB8719367D0 (en) 1987-08-15 1987-08-15 Therapeutic compounds
GB878725939A GB8725939D0 (en) 1987-11-05 1987-11-05 Therapeutic compounds

Publications (1)

Publication Number Publication Date
CY1833A true CY1833A (en) 1995-12-01

Family

ID=26292613

Family Applications (1)

Application Number Title Priority Date Filing Date
CY183395A CY1833A (en) 1987-08-15 1995-12-01 Therapeutic nucleosides

Country Status (30)

Country Link
EP (2) EP0308065B1 (pl)
JP (2) JPH0662623B2 (pl)
KR (2) KR960002849B1 (pl)
CN (1) CN1033701C (pl)
AP (2) AP160A (pl)
AT (1) ATE138660T1 (pl)
AU (1) AU612393C (pl)
CS (1) CS276903B6 (pl)
CY (1) CY1833A (pl)
DE (1) DE3855333T2 (pl)
DK (2) DK170045B1 (pl)
ES (1) ES2087639T3 (pl)
FI (1) FI89713C (pl)
GR (1) GR3020372T3 (pl)
HU (1) HU201071B (pl)
IE (1) IE65551B1 (pl)
IL (1) IL87434A (pl)
LU (1) LU88746I2 (pl)
LV (1) LV5264A3 (pl)
MC (1) MC1968A1 (pl)
MX (1) MX9203418A (pl)
MY (1) MY103760A (pl)
NL (1) NL960001I2 (pl)
NO (2) NO167805C (pl)
NZ (1) NZ225809A (pl)
PL (1) PL158285B1 (pl)
PT (1) PT88261B (pl)
SA (1) SA95160244B1 (pl)
SG (1) SG26346G (pl)
SU (1) SU1634138A3 (pl)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP160A (en) * 1987-08-15 1991-11-18 The Wellcome Foundation Ltd Therapeutic acyclic nucleosides.
GB8816760D0 (en) * 1988-07-14 1988-08-17 Wellcome Found Therapeutic compounds
GB8829571D0 (en) * 1988-12-19 1989-02-08 Wellcome Found Antiviral compounds
AU618436B2 (en) * 1988-12-19 1991-12-19 Wellcome Foundation Limited, The Antiviral cytosine and guanine derivatives
DE4008858A1 (de) * 1990-03-20 1991-09-26 Hoechst Ag Substituierte purine, verfahren zu ihrer hertellung sowie ihre verwendung als antivirale mittel
PT702683E (pt) * 1993-06-08 2004-01-30 Cancer Rec Tech Ltd Derivados de guanina o6-substituida processo para a sua preparacao e sua utilizacao no tratamento de celulas tumorais
WO1994029311A1 (en) * 1993-06-10 1994-12-22 Farmhispania Sa Amino acid ester of nucleoside analogues
GB9317146D0 (en) * 1993-08-18 1993-10-06 Wellcome Found Therapeutic combinations
GB9320316D0 (en) * 1993-10-01 1993-11-17 Smithkline Beecham Plc Pharmaceuticals
TW282470B (pl) * 1993-11-18 1996-08-01 Ajinomoto Kk
DE69513313T2 (de) * 1994-02-01 2000-07-13 Ajinomoto Co., Inc. Verfahren zur Herstellung von Nukleinsäurebasenderivaten
PE32296A1 (es) * 1994-07-28 1996-08-07 Hoffmann La Roche Ester de l-monovalina derivado de 2-(2-amino-1,6-dihidro-6-oxo-purin-9-il) metoxi-1,3-propandiol y sus sales farmaceuticamente aceptables
US5543414A (en) * 1994-07-28 1996-08-06 Syntex (Usa) Inc. Achiral amino acid acyl esters of ganciclovir and its derivatives
US6083953A (en) * 1994-07-28 2000-07-04 Syntex (U.S.A.) Inc. 2- (2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3- propanediol derivative
GB9501178D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Guanine derivative
GB9501142D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Compounds for use in medicine
GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet
DE19536164A1 (de) * 1995-09-28 1997-04-03 Boehringer Ingelheim Kg Verbessertes Verfahren zur Herstellung von 9-[(2-Hyroxyethoxy)methyl]guanin (Acyclovir)
EP0874631B1 (en) * 1996-01-19 2003-11-19 Glaxo Group Limited Use of valaciclovir for the manufacture of a medicament for the treatment of genital herpes by a single daily application
JP4094667B2 (ja) * 1996-01-26 2008-06-04 エフ・ホフマン―ラ ロシュ アーゲー プリン誘導体の製造方法
US5700936A (en) * 1996-01-26 1997-12-23 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate
US5840890A (en) * 1996-01-26 1998-11-24 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US5756736A (en) * 1996-01-26 1998-05-26 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US6040446A (en) 1996-01-26 2000-03-21 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
US5869493A (en) 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
US6703394B2 (en) 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
IT1283447B1 (it) * 1996-07-18 1998-04-21 Ind Chimica Srl Processo di preparazione del valaciclovir e relativi intermedi
EP0976750A4 (en) * 1997-01-17 2001-05-30 Ajinomoto Kk NEW Z-VALACYCLOVIR CRYSTALS
CA2332961A1 (en) * 1998-05-21 1999-11-25 Michael Zasloff A method for stimulation of defensin production by exposure to isoleucine
CZ2004446A3 (cs) * 2001-09-07 2005-01-12 Teva Pharmaceutical Industries Ltd. Krystalické formy valaciklovir hydrochloridu
WO2004000265A2 (en) 2002-06-24 2003-12-31 Ranbaxy Laboratories Limited Process for the preparation of robust formulations of valacyclovir hydrochloride tablets
US20050043329A1 (en) * 2002-09-06 2005-02-24 Shlomit Wizel Crystalline forms of valacyclovir hydrochloride
CN1309732C (zh) * 2002-10-28 2007-04-11 南京长澳医药科技有限公司 6－烷氧基－2’，3’－双脱氧鸟嘌呤核苷的制备方法
WO2005000850A2 (en) * 2003-06-02 2005-01-06 Teva Pharmaceutical Industries, Ltd. Novel crystalline forms of valacyclovir hydrochloride
CN1331471C (zh) * 2003-09-22 2007-08-15 陈云芳 盐酸万乃洛韦软胶囊组合物
US20050192296A1 (en) * 2004-01-21 2005-09-01 Zvi Harel Process for the preparation of valacyclovir hydrochloride
GB2413017A (en) * 2004-04-06 2005-10-12 Ford Global Tech Llc An electrical connector for a vehicle
WO2006035452A1 (en) * 2004-09-27 2006-04-06 Matrix Laboratories Ltd Novel pseudomorph of valaciclovir hydrochloride
ES2379804T3 (es) 2005-05-25 2012-05-03 Eli Lilly And Company Ésteres de ciclopropanocarboxilato de aciclovir
EP1746098A1 (en) 2005-07-21 2007-01-24 SOLMAG S.p.A. Valacyclovir polymorphs and a process for the preparation thereof
CN101456859B (zh) * 2009-01-06 2011-07-20 华南理工大学 抗病毒药物缬昔洛韦的制备方法
WO2011158252A1 (en) 2010-06-15 2011-12-22 Matrix Laboratories Ltd Process for the preparation of valacyclovir hydrochloride polymorphic form ii
CN102850354B (zh) * 2012-10-10 2014-07-23 山东金城医药化工股份有限公司 高纯度cbz-万乃洛韦的制备方法
CN106632335A (zh) * 2016-12-27 2017-05-10 河南康达制药有限公司 一种盐酸伐昔洛韦的制备方法
RU2750867C1 (ru) * 2020-05-18 2021-07-05 Александр Сергеевич Самойлов Производные гуанина

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8202626A (nl) * 1982-06-29 1984-01-16 Stichting Rega V Z W Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
DE3627024A1 (de) * 1985-09-24 1987-04-02 Hoechst Ag In 6- und 9-stellung substituierte 2-aminopurine, ihre verwendung, diese purine enthaltende arzneimittel und verfahren zur herstellung der purine
DE3534774A1 (de) * 1985-09-30 1987-04-02 Robugen Gmbh Nucleosid-analoge verbindungen mit antiviraler aktivitaet, verfahren zu deren herstellung sowie arzneimittel mit antiviraler wirkung
AP160A (en) * 1987-08-15 1991-11-18 The Wellcome Foundation Ltd Therapeutic acyclic nucleosides.

Also Published As

Publication number Publication date
IE65551B1 (en) 1995-11-01
FI89713B (fi) 1993-07-30
DK451388A (da) 1989-02-16
ES2087639T3 (es) 1996-07-16
DK170803B1 (da) 1996-01-22
IL87434A0 (en) 1989-01-31
FI883757A0 (fi) 1988-08-12
HU201071B (en) 1990-09-28
FI883757L (fi) 1989-02-16
ATE138660T1 (de) 1996-06-15
CS276903B6 (en) 1992-09-16
JPH0662623B2 (ja) 1994-08-17
JPS6468373A (en) 1989-03-14
KR960004940B1 (ko) 1996-04-18
AP8800099A0 (en) 1988-08-01
MC1968A1 (fr) 1989-09-29
CS8805594A2 (en) 1990-06-13
AP160A (en) 1991-11-18
IE882463L (en) 1989-02-15
IL87434A (en) 1993-06-10
DE3855333D1 (de) 1996-07-04
PL274215A1 (en) 1990-02-19
LV5264A3 (lv) 1993-10-10
EP0308065A3 (en) 1989-09-27
EP0596542A1 (en) 1994-05-11
CN1032538A (zh) 1989-04-26
EP0308065B1 (en) 1995-01-04
PT88261B (pt) 1995-03-01
EP0308065A2 (en) 1989-03-22
DE3855333T2 (de) 1996-12-05
AU2097888A (en) 1989-02-16
AU612393C (en) 2006-08-17
KR960002849B1 (ko) 1996-02-27
MY103760A (en) 1993-09-30
NL960001I2 (nl) 1996-11-01
EP0596542B1 (en) 1996-05-29
GR3020372T3 (en) 1996-09-30
JPH07113025B2 (ja) 1995-12-06
NZ225809A (en) 1991-07-26
SU1634138A3 (ru) 1991-03-07
PT88261A (pt) 1989-06-30
NO1996015I1 (no) 1996-12-17
JPH03115284A (ja) 1991-05-16
SG26346G (en) 1995-09-01
NO883612D0 (no) 1988-08-12
NO167805B (no) 1991-09-02
AP55A (en) 1989-09-26
CN1033701C (zh) 1997-01-01
MX9203418A (es) 1992-07-01
PL158285B1 (en) 1992-08-31
DK170045B1 (da) 1995-05-08
KR890003761A (ko) 1989-04-17
DK82694A (da) 1994-07-08
SA95160244B1 (ar) 2006-10-02
NO883612L (no) 1989-02-16
AU612393B2 (en) 1991-07-11
LU88746I2 (fr) 1996-10-04
HUT47935A (en) 1989-04-28
DK451388D0 (da) 1988-08-12
NO167805C (no) 1991-12-11
FI89713C (fi) 1993-11-10
NL960001I1 (nl) 1996-03-01

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