CY1115010T1 - ΕΝΑΣ ΜΟΛΥΣΜΑΤΙΚΟΣ cDNA ΚΛΩΝΟΣ ΤΟΥ ΙΟΥ ΤΟΥ ΧΟΙΡΕΙΟΥ ΑΝΑΠΑΡΑΓΩΓΙΚΟΥ ΚΑΙ ΑΝΑΠΝΕΥΣΤΙΚΟΥ ΣΥΝΔΡΟΜΟΥ ΒΟΡΕΙΟΥ ΑΜΕΡΙΚΗΣ (PRRS) ΚΑΙ ΧΡΗΣΕΙΣ ΑΥΤΟΥ - Google Patents

ΕΝΑΣ ΜΟΛΥΣΜΑΤΙΚΟΣ cDNA ΚΛΩΝΟΣ ΤΟΥ ΙΟΥ ΤΟΥ ΧΟΙΡΕΙΟΥ ΑΝΑΠΑΡΑΓΩΓΙΚΟΥ ΚΑΙ ΑΝΑΠΝΕΥΣΤΙΚΟΥ ΣΥΝΔΡΟΜΟΥ ΒΟΡΕΙΟΥ ΑΜΕΡΙΚΗΣ (PRRS) ΚΑΙ ΧΡΗΣΕΙΣ ΑΥΤΟΥ

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Publication number
CY1115010T1
CY1115010T1 CY20141100252T CY141100252T CY1115010T1 CY 1115010 T1 CY1115010 T1 CY 1115010T1 CY 20141100252 T CY20141100252 T CY 20141100252T CY 141100252 T CY141100252 T CY 141100252T CY 1115010 T1 CY1115010 T1 CY 1115010T1
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north american
american prrs
viral vectors
viruses
prrs
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CY20141100252T
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Jay Gregory Calvert
Siao-Kun Wan Welch
Michael George Sheppard
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Zoetis P Llc
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Publication of CY1115010T1 publication Critical patent/CY1115010T1/el

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Abstract

Η εφεύρεση παρέχει απομονωμένα πολυνουκλεοτιδικά μόρια, συμπεριλαμβανομένων πλασμιδίων, ιικών φορέων, επιμολυσμένων κυττάρων ξενιστών που περιλαμβάνουν μια DNA ακολουθία που κωδικοποιεί μία μολυσματική RNA ακολουθία που κωδικοποιεί ένα ιό PRRS Βορείου Αμερικής, και επίσης PRRS ιούς Βορείου Αμερικής που κωδικοποιούνται από αυτή. Η εφεύρεση περαιτέρω παρέχει απομονωμένα μολυσματικά RNA μόρια που κωδικοποιούν ένα PRRS ιό Βορείου Αμερικής. Η εφεύρεση επίσης παρέχει απομονωμένα πολυνουκλεοτιδικά μόρια, μολυσματικά RNA μόρια, ιικούς φορείς και επιμολυσμένα κύτταρα ξενιστές που κωδικοποιούν γενετικά τροποποιημένους PRRS ιούς Βορείου Αμερικής, και γενετικά τροποποιημένους PRRS ιούς Βορείου Αμερικής που κωδικοποιούνται από αυτά. Η εφεύρεση επίσης παρέχει εμβόλια που περιλαμβάνουν τέτοια πλασμίδια, RNA μόρια, ιικούς φορείς και PRRS ιούς Βορείου Αμερικής και μεθόδους που χρησιμοποιούν αυτά τα εμβόλια σε χοίρους και σε άλλα ζώα. Επίσης παρέχονται απομονωμένα πολυνουκλεοτιδικά μόρια, ιικοί φορείς και επιμολυσμένα κύτταρα ξενιστές που περιλαμβάνουν μία νουκλεοτιδική ακολουθία που κωδικοποιεί ένα πεπτίδιο του ιού PRRS Βορείου Αμερικής. Αυτοί οι ιικοί φορείς και οι επιμολυσμένες κυτταρικές σειρές ξενιστές είναι χρήσιμοι για την προμήθεια πεπτιδίων για να αντισταθμίσουν πεπτίδια που κωδικοποιούνται από μεταλλαγμένες DNA ακολουθίες που κωδικοποιούν γενετικά τροποποιημένους PRRS ιούς Βορείου Αμερικής έτσι ώστε να μπορούν να δημιουργηθούν λειτουργικά ιοσωμάτια.
CY20141100252T 1998-12-22 2014-04-03 ΕΝΑΣ ΜΟΛΥΣΜΑΤΙΚΟΣ cDNA ΚΛΩΝΟΣ ΤΟΥ ΙΟΥ ΤΟΥ ΧΟΙΡΕΙΟΥ ΑΝΑΠΑΡΑΓΩΓΙΚΟΥ ΚΑΙ ΑΝΑΠΝΕΥΣΤΙΚΟΥ ΣΥΝΔΡΟΜΟΥ ΒΟΡΕΙΟΥ ΑΜΕΡΙΚΗΣ (PRRS) ΚΑΙ ΧΡΗΣΕΙΣ ΑΥΤΟΥ CY1115010T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11334598P 1998-12-22 1998-12-22
EP20050018141 EP1627919B1 (en) 1998-12-22 1999-11-25 An infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof

Publications (1)

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CY1115010T1 true CY1115010T1 (el) 2016-12-14

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Family Applications (2)

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CY061100160T CY1105680T1 (el) 1998-12-22 2006-02-07 Μολυσματικος κλωνος cdna βορειοαμερικανικου ιου χοιρειου αναπαραγωγικου και αναπνευστικου συνδρομου (prrs) και χρησεις αυτου
CY20141100252T CY1115010T1 (el) 1998-12-22 2014-04-03 ΕΝΑΣ ΜΟΛΥΣΜΑΤΙΚΟΣ cDNA ΚΛΩΝΟΣ ΤΟΥ ΙΟΥ ΤΟΥ ΧΟΙΡΕΙΟΥ ΑΝΑΠΑΡΑΓΩΓΙΚΟΥ ΚΑΙ ΑΝΑΠΝΕΥΣΤΙΚΟΥ ΣΥΝΔΡΟΜΟΥ ΒΟΡΕΙΟΥ ΑΜΕΡΙΚΗΣ (PRRS) ΚΑΙ ΧΡΗΣΕΙΣ ΑΥΤΟΥ

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CY061100160T CY1105680T1 (el) 1998-12-22 2006-02-07 Μολυσματικος κλωνος cdna βορειοαμερικανικου ιου χοιρειου αναπαραγωγικου και αναπνευστικου συνδρομου (prrs) και χρησεις αυτου

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US (2) US6500662B1 (el)
EP (2) EP1018557B9 (el)
JP (7) JP4113642B2 (el)
CN (1) CN1171996C (el)
AR (2) AR025146A1 (el)
AT (1) ATE309364T1 (el)
AU (1) AU769841B2 (el)
BR (1) BRPI9905902B8 (el)
CA (2) CA2290220C (el)
CY (2) CY1105680T1 (el)
DE (1) DE69928209T9 (el)
DK (2) DK1627919T3 (el)
ES (2) ES2251162T3 (el)
HK (1) HK1029140A1 (el)
MX (1) MXPA03009354A (el)
NZ (2) NZ513289A (el)
PT (1) PT1627919E (el)
ZA (1) ZA997289B (el)

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