CY1105680T1 - Μολυσματικος κλωνος cdna βορειοαμερικανικου ιου χοιρειου αναπαραγωγικου και αναπνευστικου συνδρομου (prrs) και χρησεις αυτου - Google Patents

Μολυσματικος κλωνος cdna βορειοαμερικανικου ιου χοιρειου αναπαραγωγικου και αναπνευστικου συνδρομου (prrs) και χρησεις αυτου

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Publication number
CY1105680T1
CY1105680T1 CY061100160T CY061100160T CY1105680T1 CY 1105680 T1 CY1105680 T1 CY 1105680T1 CY 061100160 T CY061100160 T CY 061100160T CY 061100160 T CY061100160 T CY 061100160T CY 1105680 T1 CY1105680 T1 CY 1105680T1
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Cyprus
Prior art keywords
north american
viruses
encoding
viral vectors
host cells
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CY061100160T
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English (en)
Inventor
Jay Gregory Calvert
Siao-Kun Wan Welch
Michael George Sheppard
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Pfizer Products Inc.
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Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of CY1105680T1 publication Critical patent/CY1105680T1/el

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Abstract

Η εφεύρεση παρέχει απομονωμένα μόρια πολυνουκλεοτιδίων, που περιλαμβάνουν πλασμίδια, ιικούς φορείς, και διαμολυσμένα κύτταρα-ξενιστές που περιλαμβάνουν αλληλουχία DNA που κωδικοποιεί μολυσματική αλληλουχία RNA που κωδικοποιεί Βορειοαμερικανικό ιό PRRS, και επίσης Βορειοαμερικανικούς ιούς PRRS που κωδικοποιούνται από αυτά τα απομονωμένα μόρια πολυνουκλεοτιδίων. Η εφεύρεση παρέχει επιπλέον απομονωμένα μολυσματικά μόρια RNA που κωδικοποιούν Βορειοαμερικανικό ιό PRRS. Η εφεύρεση παρέχει επίσης απομονωμένα μόρια πολυνουκλεοτιδίων, μολυσματικά μόρια RNA, ιικούς φορείς, και διαμολυσμένα κύτταρα-ξενιστές που κωδικοποιούν γενετικά τροποποιημένους Βορειοαμερικανικούς ιούς PRRS, και γενετικά τροποποιημένους Βορειοαμερικανικούς ιούς PRRS που κωδικοποιούνται από αυτά τα απομονωμένα μόρια πολυνουκλεοτιδίων. Η εφεύρεση παρέχει επίσης εμβόλια που περιλαμβάνουν αυτά τα πλασμίδια, μόρια RNA, ιικούς φορείς και Βορειοαμερικανικούς ιούς PRRS, και μεθόδους χρήσης αυτών των εμβολίων σε χοιροειδή και σε άλλα ζώα. Παρέχονται επίσης απομονωμένα μόρια πολυνουκλεοτιδίων, ιικοί φορείς, και διαμολυσμένα κύτταρα-ξενιστές που περιλαμβάνουν αλληλουχία νουκλεοτιδίων που κωδικοποιεί πεπτίδιο Βορειοαμερικανικού ιού PRRS. Αυτοί οι ιικοί φορείς και κυτταρικές σειρές διαμολυσμένων κυττάρων-ξενιστών χρησιμεύουν στο να παρέχουν πεπτίδια που να αναπληρώνουν αλληλουχίες που κωδικοποιούν μεταλλαγμένα πεπτίδια των αλληλουχιών DNA που κωδικοποιούν γενετικά τροποποιημένους Βορειοαμερικανικούς ιούς PRRS έτσι ώστε να παράγονται λειτουργικά ιοσώματα.
CY061100160T 1998-12-22 2006-02-07 Μολυσματικος κλωνος cdna βορειοαμερικανικου ιου χοιρειου αναπαραγωγικου και αναπνευστικου συνδρομου (prrs) και χρησεις αυτου CY1105680T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11334598P 1998-12-22 1998-12-22
EP19990309409 EP1018557B9 (en) 1998-12-22 1999-11-25 Infectious cDNA clone of north american porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof

Publications (1)

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CY1105680T1 true CY1105680T1 (el) 2014-07-02

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ID=22348908

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Application Number Title Priority Date Filing Date
CY061100160T CY1105680T1 (el) 1998-12-22 2006-02-07 Μολυσματικος κλωνος cdna βορειοαμερικανικου ιου χοιρειου αναπαραγωγικου και αναπνευστικου συνδρομου (prrs) και χρησεις αυτου
CY20141100252T CY1115010T1 (el) 1998-12-22 2014-04-03 ΕΝΑΣ ΜΟΛΥΣΜΑΤΙΚΟΣ cDNA ΚΛΩΝΟΣ ΤΟΥ ΙΟΥ ΤΟΥ ΧΟΙΡΕΙΟΥ ΑΝΑΠΑΡΑΓΩΓΙΚΟΥ ΚΑΙ ΑΝΑΠΝΕΥΣΤΙΚΟΥ ΣΥΝΔΡΟΜΟΥ ΒΟΡΕΙΟΥ ΑΜΕΡΙΚΗΣ (PRRS) ΚΑΙ ΧΡΗΣΕΙΣ ΑΥΤΟΥ

Family Applications After (1)

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CY20141100252T CY1115010T1 (el) 1998-12-22 2014-04-03 ΕΝΑΣ ΜΟΛΥΣΜΑΤΙΚΟΣ cDNA ΚΛΩΝΟΣ ΤΟΥ ΙΟΥ ΤΟΥ ΧΟΙΡΕΙΟΥ ΑΝΑΠΑΡΑΓΩΓΙΚΟΥ ΚΑΙ ΑΝΑΠΝΕΥΣΤΙΚΟΥ ΣΥΝΔΡΟΜΟΥ ΒΟΡΕΙΟΥ ΑΜΕΡΙΚΗΣ (PRRS) ΚΑΙ ΧΡΗΣΕΙΣ ΑΥΤΟΥ

Country Status (18)

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US (2) US6500662B1 (el)
EP (2) EP1627919B1 (el)
JP (7) JP4113642B2 (el)
CN (1) CN1171996C (el)
AR (2) AR025146A1 (el)
AT (1) ATE309364T1 (el)
AU (1) AU769841B2 (el)
BR (1) BRPI9905902B8 (el)
CA (2) CA2440933A1 (el)
CY (2) CY1105680T1 (el)
DE (1) DE69928209T9 (el)
DK (2) DK1018557T5 (el)
ES (2) ES2251162T3 (el)
HK (1) HK1029140A1 (el)
MX (1) MXPA03009354A (el)
NZ (2) NZ513289A (el)
PT (1) PT1627919E (el)
ZA (1) ZA997289B (el)

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