BRPI0606539A2 - vacinas aperfeiçoadas contra a prrs - Google Patents

vacinas aperfeiçoadas contra a prrs

Info

Publication number
BRPI0606539A2
BRPI0606539A2 BRPI0606539-2A BRPI0606539A BRPI0606539A2 BR PI0606539 A2 BRPI0606539 A2 BR PI0606539A2 BR PI0606539 A BRPI0606539 A BR PI0606539A BR PI0606539 A2 BRPI0606539 A2 BR PI0606539A2
Authority
BR
Brazil
Prior art keywords
vaccines
prrs vaccines
improved
improved prrs
prrs
Prior art date
Application number
BRPI0606539-2A
Other languages
English (en)
Inventor
Christiane Fetzer
Stefan Pesch
Original Assignee
Boehringer Ingelheim Vetmedica Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmedica Gmbh filed Critical Boehringer Ingelheim Vetmedica Gmbh
Publication of BRPI0606539A2 publication Critical patent/BRPI0606539A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

VACINAS APERFEIçOADAS CONTRA A PRRS. A presente invenção refere-se as vacinas contra PRRS com vírus vivos modificados aperfeiçoadas de genótipo Europeu e novas cepas de PRRSV que podem ser usadas para a fabricação de tais vacinas.
BRPI0606539-2A 2005-01-13 2006-01-09 vacinas aperfeiçoadas contra a prrs BRPI0606539A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05000542 2005-01-13
PCT/EP2006/050098 WO2006074986A2 (en) 2005-01-13 2006-01-09 Prrs vaccines

Publications (1)

Publication Number Publication Date
BRPI0606539A2 true BRPI0606539A2 (pt) 2009-06-30

Family

ID=36677986

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0606539-2A BRPI0606539A2 (pt) 2005-01-13 2006-01-09 vacinas aperfeiçoadas contra a prrs

Country Status (16)

Country Link
US (1) US7368117B2 (pt)
EP (1) EP1838343B1 (pt)
JP (1) JP2008526921A (pt)
KR (1) KR20070096019A (pt)
CN (1) CN101189027A (pt)
AR (1) AR053327A1 (pt)
AT (1) ATE462445T1 (pt)
AU (1) AU2006205852A1 (pt)
BR (1) BRPI0606539A2 (pt)
CA (1) CA2587321A1 (pt)
DE (1) DE602006013270D1 (pt)
ES (1) ES2343201T3 (pt)
MY (1) MY139896A (pt)
RU (1) RU2007130801A (pt)
WO (1) WO2006074986A2 (pt)
ZA (1) ZA200703663B (pt)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
FR2772047B1 (fr) 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
AU3198200A (en) 1999-03-08 2000-09-28 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Prrsv vaccines
DK2251419T3 (da) 1999-04-22 2012-07-02 Us Agriculture Porcint reproduktions- og respirations-syndrom-vaccine baseret på isolat JA-142
CA2571452A1 (en) 2004-06-18 2006-01-26 Regents Of The University Of Minnesota Identifying virally infected and vaccinated organisms
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
UA95602C2 (ru) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
US7700285B1 (en) 2005-12-29 2010-04-20 Boehringer Ingelheim Vetmedica, Inc. PCV2 immunogenic compositions and methods of producing such compositions
US7833707B2 (en) * 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
PT1904631E (pt) * 2005-06-24 2012-07-16 Univ Minnesota Vírus srrp, clones infecciosos, os seus mutantes e processos de utilização
MX356667B (es) 2005-12-29 2018-06-08 Boehringer Ingelheim Vetmedica Inc Uso de una composicion inmunogenica de pcv2 para reducir los sintomas clinicos en cerdos.
KR101436794B1 (ko) 2005-12-29 2014-09-04 베링거잉겔하임베트메디카인코퍼레이티드 다가 ｐｃｖ2 면역원성 조성물 및 이러한 조성물의 제조방법
US20100136060A1 (en) * 2006-11-22 2010-06-03 Boehringer Ingelheim Vetmedica, Inc. Methods of reducing porcine circovirus-associated disease outbreaks
WO2008073464A2 (en) 2006-12-11 2008-06-19 Boehringer Ingelheim Vetmedica, Inc. Effective method of treatment of porcine circovirus and lawsonia intracellularis infections
DK2094872T4 (da) * 2006-12-15 2020-05-18 Boehringer Ingelheim Animal Health Usa Inc Behandling af anti-PCV2-antistofseropositive svin med PCV2-antigen
EP1941903A1 (en) * 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxis and treatment of PRDC
EP1958644A1 (en) * 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Prevention and treatment of sub-clinical pcvd
CN100439494C (zh) * 2007-03-14 2008-12-03 中国动物疫病预防控制中心 猪繁殖与呼吸综合征疫苗、制备方法及应用
WO2008121958A1 (en) * 2007-04-02 2008-10-09 Boehringer Ingelheim Vetmedica, Inc. Use of prrsv vaccines to reduce pcv2 viremia
US7829274B2 (en) 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
CN101932336B (zh) * 2007-12-31 2014-07-09 贝林格尔.英格海姆维特梅迪卡有限公司 有外来氨基酸插入的pcv2 orf2病毒样颗粒
WO2009126356A2 (en) * 2008-01-23 2009-10-15 Boehringer Ingelheim Vetmedica, Inc. Pcv2 mycoplasma hyopneumoniae immunogenic compositions and methods of producing such compositions
US20100003278A1 (en) * 2008-07-03 2010-01-07 Boehringer Ingelheim Vetmedica, Inc. Immunological Compositions Effective for Lessening the Severity or Incidence of PRRSV Signs and Methods of Use Thereof
CN102316895A (zh) * 2008-08-25 2012-01-11 贝林格尔.英格海姆维特梅迪卡有限公司 抗高致病性猪生殖与呼吸综合征(hp prrs)的疫苗
TWI627281B (zh) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物
FR2957803B1 (fr) * 2010-03-24 2012-06-01 Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic Diluants adjuvants de vaccins vivants pour maladies porcines
EP2558118B1 (en) * 2010-04-16 2019-06-05 Universiteit Gent Cross-protecting vaccine for porcine reproductive and respiratory syndrome virus
CN103370077B (zh) 2011-02-17 2016-10-26 贝林格尔.英格海姆维特梅迪卡有限公司 猪繁殖与呼吸综合征病毒的商业化规模生产方法
MY186535A (en) 2011-02-17 2021-07-26 Boehringer Ingelheim Vetmedica Gmbh Novel european prrsv strain
WO2012177739A2 (en) 2011-06-20 2012-12-27 Siemens Healthcare Diagnostics Inc. Reagents and methods for detecting hcv
KR101281361B1 (ko) * 2011-07-18 2013-07-02 서울대학교산학협력단 북미형 돼지 생식기 호흡기 증후군 바이러스 예방 백신 조성물 및 이를 포함하는 혼합백신 조성물
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
EP2737059A1 (en) 2011-07-29 2014-06-04 Boehringer Ingelheim Vetmedica GmbH Novel prrs virus inducing type i interferon in susceptible cells
UA114504C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs
UA114503C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv та mycoplasma hyopneumoniae
US9120859B2 (en) 2012-04-04 2015-09-01 Zoetis Services Llc Mycoplasma hyopneumoniae vaccine
US9457073B2 (en) * 2012-09-26 2016-10-04 University Of Manitoba Live attenuated replication-competent arteriviruses having decreased dub/deisgylating activity
WO2014089117A1 (en) * 2012-12-07 2014-06-12 The Board Of Trustees Of The University Of Illinois Porcine reproductive and respiratory syndrome virus compositions and uses thereof
WO2014150822A2 (en) 2013-03-15 2014-09-25 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
CN105579060B (zh) 2013-09-25 2021-03-16 硕腾服务有限责任公司 Pcv2b趋异株疫苗组合物以及使用方法
CA2924228C (en) 2013-10-02 2024-01-16 Boehringer Ingelheim Vetmedica, Inc. Pcv2 orf2 protein variant and virus like particles composed thereof
KR102446025B1 (ko) 2013-12-20 2022-09-22 베링거잉겔하임베트메디카게엠베하 Ｐｒｒｓ 바이러스 변이체, 유럽형 ｐｒｒｓ 바이러스 ｃｄｎａ 클론, 및 이들의 용도
JP2019509302A (ja) 2016-03-23 2019-04-04 インターベット インターナショナル ベー． フェー． アルブミンを含むｐｃｖ２及びｐｒｒｓウイルス感染症に対する混合ワクチン
CN108697782A (zh) 2016-03-23 2018-10-23 英特维特国际股份有限公司 针对pcv2病毒和猪肺炎支原体感染的组合疫苗
BR112018069219A2 (pt) 2016-03-23 2019-01-22 Intervet Int Bv uma vacina para aplicação intradérmica contra infecção pelo vírus pcv2 e prrs
BR112019010394A2 (pt) 2016-11-29 2019-09-03 Intervet Int Bv vacina suína
EP3609533A1 (en) 2017-04-13 2020-02-19 Intervet International B.V. Vaccines containing swine pathogens for associated non-mixed use
US20230338500A1 (en) 2020-04-20 2023-10-26 Intervet Inc. A combination of vaccines to prophylactically treat a pig

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992021375A1 (en) * 1991-06-06 1992-12-10 Stichting Centraal Diergeneeskundig Instituut Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
US6042830A (en) * 1992-08-05 2000-03-28 Boehringer Ingelheim Vetmedica, Inc. Viral agent associated with mystery swine disease
SG43852A1 (en) 1991-08-26 1997-11-14 Boehringer Animal Health Inc Sirs vaccine and diagnosis method
WO1993006211A1 (en) 1991-09-16 1993-04-01 Collins James E Vaccine for mystery swine disease and method for diagnosis thereof
DE69206631T2 (de) 1991-10-14 1996-05-15 Akzo Nobel Nv Impfstoff gegen das Fortpflanzungs- und Atmungssyndrom bei Schweinen (PRRS) und Diagnose.
ATE206455T1 (de) * 1994-04-11 2001-10-15 Akzo Nobel Nv Europäische vakzinstämme des fortplanzungs- atmungs-syndromsvirus des schweins
EP0732340B1 (en) 1995-03-14 2004-06-09 Akzo Nobel N.V. Expression of porcine reproductive respiratory syndrome virus polypeptides in the same cell
PT835930E (pt) * 1996-10-09 2001-06-29 Akzo Nobel Nv Estirpes europeias de vacina do virus do sindroma reprodutivo e respiratorio porcino (prrsv)
EP0839912A1 (en) 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
CA2290220C (en) 1998-12-22 2013-11-19 Pfizer Products Inc. An infectious cdna clone of north american porcine reproductive and respiratory syndrome (prrs) virus and uses thereof
US6841364B2 (en) 2002-01-22 2005-01-11 Protatek International, Inc. Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof

Also Published As

Publication number Publication date
US20060286123A1 (en) 2006-12-21
WO2006074986A2 (en) 2006-07-20
ES2343201T3 (es) 2010-07-26
JP2008526921A (ja) 2008-07-24
CN101189027A (zh) 2008-05-28
RU2007130801A (ru) 2009-02-20
AR053327A1 (es) 2007-05-02
DE602006013270D1 (en) 2010-05-12
EP1838343A2 (en) 2007-10-03
WO2006074986A3 (en) 2007-11-15
ZA200703663B (en) 2008-07-30
AU2006205852A1 (en) 2006-07-20
MY139896A (en) 2009-11-30
KR20070096019A (ko) 2007-10-01
US7368117B2 (en) 2008-05-06
EP1838343B1 (en) 2010-03-31
CA2587321A1 (en) 2006-07-20
ATE462445T1 (de) 2010-04-15

Similar Documents

Publication Publication Date Title
BRPI0606539A2 (pt) vacinas aperfeiçoadas contra a prrs
CR10528A (es) Proceso para producir poxvirus y composiciones de poxvirus
HN2006011218A (es) Composiciones de tigeciclina y métodos de preparación
BR112012014082A2 (pt) composições e métodos que compreendem variantes de protease
BRPI0607896A2 (pt) combinações de compostos ativos com propriedades inseticidas e acaricidas
ATE523207T1 (de) Stabilisatoren für gefriergetrocknete impfstoffe
CR20110206A (es) Método de uso de una sepa de bacillus subtilis para mejorar la salud de animales
GT200800276A (es) Composiciones farmaceuticas estabilizadas que comprenden fesoterodina
MY186535A (en) Novel european prrsv strain
EA200970581A1 (ru) Кристаллическое твёрдое основание разагилина
MX2009004862A (es) Estabilizacion de vacunas por liofilizacion.
CR11031A (es) Composiciones de enzima digestiva estable
BRPI0710508B8 (pt) composição de pepticorpo terapêutico liofilizado estável, kit para preparar uma composição farmacêutica aquosa, e métodos para fabricar um pepticorpo terapêutico liofilizado e para preparar uma composição de pepticorpo terapêutico reconstituído
MX2010008779A (es) Sistemas de productos estables en almacenamiento para formulaciones de pre-mezcla.
MX2009010798A (es) Metodos y composiciones para virus atenuados vivos.
EA201001639A1 (ru) Композиции и способы их получения и применения
MY144689A (en) Dengue serotype 1 attenuated strain
MX2011008649A (es) Vacuna contra el virus del dengue inactivado con un adyuvante libre de aluminio.
MX2019004464A (es) Cerdos que comprenden cd163 modificada y metodos asociados.
CR9246A (es) Formulaciones terapeuticas del factor de crecimiento de queratinocitos
BRPI0911907B8 (pt) processo para produzir uma composição contendo triptofano e composição proteica contendo triptofano
WO2006078648A3 (en) Rhinovirus vaccines
CL2011000262A1 (es) Virus de bronquitis infecciosa (bi) derivado de un virus similar a qx-bi; composicion de vacuna que comprende dicho virus; procedimiento para preparar dicho virus.
PA8624401A1 (es) Procesos para la preparacion de haluros de aril- y heteroaril-alquilsulfonilo
JP2010536929A5 (pt)

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE A 6A ANUIDADE.