CY1114214T1 - Lys-Pro-Thr KAI Lys-Pro ΩΣ ΕΝΩΣΕΙΣ ΠΟΥ ΑΝΑΣΤΕΛΛΟΥΝ ΤΗ ΦΛΕΓΜΟΝΗ - Google Patents
Lys-Pro-Thr KAI Lys-Pro ΩΣ ΕΝΩΣΕΙΣ ΠΟΥ ΑΝΑΣΤΕΛΛΟΥΝ ΤΗ ΦΛΕΓΜΟΝΗInfo
- Publication number
- CY1114214T1 CY1114214T1 CY20131100702T CY131100702T CY1114214T1 CY 1114214 T1 CY1114214 T1 CY 1114214T1 CY 20131100702 T CY20131100702 T CY 20131100702T CY 131100702 T CY131100702 T CY 131100702T CY 1114214 T1 CY1114214 T1 CY 1114214T1
- Authority
- CY
- Cyprus
- Prior art keywords
- pro
- lys
- thr
- kai
- components
- Prior art date
Links
- 206010061218 Inflammation Diseases 0.000 title 1
- 108010065920 Insulin Lispro Proteins 0.000 title 1
- AIXUQKMMBQJZCU-IUCAKERBSA-N Lys-Pro Chemical compound NCCCC[C@H](N)C(=O)N1CCC[C@H]1C(O)=O AIXUQKMMBQJZCU-IUCAKERBSA-N 0.000 title 1
- LOGFVTREOLYCPF-RHYQMDGZSA-N Lys-Pro-Thr Chemical compound C[C@@H](O)[C@@H](C(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCCN LOGFVTREOLYCPF-RHYQMDGZSA-N 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- 108010013842 interleukin 1beta (193-195) Proteins 0.000 title 1
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 125000000174 L-prolyl group Chemical group [H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(*)=O 0.000 abstract 1
- GVUVRRPYYDHHGK-VQVTYTSYSA-N Pro-Thr Chemical compound C[C@@H](O)[C@@H](C(O)=O)NC(=O)[C@@H]1CCCN1 GVUVRRPYYDHHGK-VQVTYTSYSA-N 0.000 abstract 1
- 206010052779 Transplant rejections Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
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- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
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Abstract
Η παρούσα εφεύρεση αφορά τη χρησιμοποίηση μιας ένωσης του τύπου Lys-X, όπου Χ είναι μια υδροξυλομάδα, μια αμινομάδα, μια αλκοξυ-ομάδα, Pro ή Pro-Thr, ή ένα από φαρμακευτικής άποψης συμβατό άλας αυτών, για τη θεραπευτική αγωγή αυτοάνοσων ασθενειών, αλλεργικών αντιδράσεων και απόρριψης μοσχεύματος.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10106852A DE10106852A1 (de) | 2001-02-14 | 2001-02-14 | Entzündungshemmende Verbindungen |
EP10154655.4A EP2196202B1 (de) | 2001-02-14 | 2002-02-08 | Lys-Pro-Thr und Lys-Pro als entzündungshemmende Verbindungen |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1114214T1 true CY1114214T1 (el) | 2016-08-31 |
Family
ID=7674019
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20071100596T CY1106563T1 (el) | 2001-02-14 | 2007-05-07 | Φλεγμονο-ανασταλτικες ενωσεις |
CY20111100430T CY1111450T1 (el) | 2001-02-14 | 2011-05-04 | Ενωσεις που αναστελλουν τη φλεγμονη |
CY20131100431T CY1114024T1 (el) | 2001-02-14 | 2013-05-30 | Ενωσεις που αναστελλουν τη φλεγμονη |
CY20131100702T CY1114214T1 (el) | 2001-02-14 | 2013-08-14 | Lys-Pro-Thr KAI Lys-Pro ΩΣ ΕΝΩΣΕΙΣ ΠΟΥ ΑΝΑΣΤΕΛΛΟΥΝ ΤΗ ΦΛΕΓΜΟΝΗ |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20071100596T CY1106563T1 (el) | 2001-02-14 | 2007-05-07 | Φλεγμονο-ανασταλτικες ενωσεις |
CY20111100430T CY1111450T1 (el) | 2001-02-14 | 2011-05-04 | Ενωσεις που αναστελλουν τη φλεγμονη |
CY20131100431T CY1114024T1 (el) | 2001-02-14 | 2013-05-30 | Ενωσεις που αναστελλουν τη φλεγμονη |
Country Status (18)
Country | Link |
---|---|
US (4) | US8003608B2 (el) |
EP (6) | EP2189156A1 (el) |
JP (1) | JP4259870B2 (el) |
CN (3) | CN101810847B (el) |
AT (2) | ATE502632T1 (el) |
AU (2) | AU2002253000B2 (el) |
CA (1) | CA2437788C (el) |
CY (4) | CY1106563T1 (el) |
DE (3) | DE10106852A1 (el) |
DK (4) | DK2198723T3 (el) |
ES (4) | ES2361422T3 (el) |
HK (4) | HK1140960A1 (el) |
MX (1) | MXPA03007255A (el) |
NZ (2) | NZ528191A (el) |
PL (3) | PL223229B1 (el) |
PT (4) | PT2198723E (el) |
SI (4) | SI2196202T1 (el) |
WO (1) | WO2002064131A2 (el) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10106852A1 (de) | 2001-02-14 | 2002-09-05 | T Luger | Entzündungshemmende Verbindungen |
US7341992B2 (en) * | 2001-05-25 | 2008-03-11 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Lectin-like domain of thrombomodulin and its therapeutic use |
US20090232866A1 (en) | 2003-10-07 | 2009-09-17 | Mariann Pavone-Gyongyosi | Oligopeptides as coating material for medical products |
WO2006009325A1 (ja) * | 2004-07-23 | 2006-01-26 | Ono Pharmaceutical Co., Ltd. | メタロプロテアーゼ阻害剤 |
JPWO2006046746A1 (ja) * | 2004-10-26 | 2008-05-22 | 味の素株式会社 | 内臓痛予防・治療剤 |
JPWO2007004613A1 (ja) * | 2005-07-01 | 2009-01-29 | 味の素株式会社 | 炎症性腸疾患治療薬及びTNF−α産生抑制剤 |
EP1782819A1 (en) * | 2005-11-03 | 2007-05-09 | Cognis IP Management GmbH | Oligopeptides and their use |
DE102006003854A1 (de) * | 2006-01-26 | 2007-08-02 | Universität Duisburg-Essen | Regulatorische und cytotoxische CD8+ T-Zellen |
CA2703891A1 (en) * | 2007-11-19 | 2009-05-28 | Universitaetsklinikum Muenster | Compositions for reducing oxidative stress and uses thereof |
US9156881B2 (en) | 2011-09-23 | 2015-10-13 | Westfaelische Wilhelms-Universitaet Muenster | Tripeptide KDPT for antiapoptotic treatment |
KR20140136494A (ko) | 2012-03-20 | 2014-11-28 | 헬릭스 바이오메딕스, 인코포레이티드 | 짧은 항균 지질펩티드 |
AU2014262517B2 (en) * | 2013-05-10 | 2018-10-18 | Southern Research Institute | Compounds, compositions and methods for the treatment of diseases through inhibiting TGF-beta activity |
PL3049428T3 (pl) * | 2013-09-23 | 2019-07-31 | Dr. August Wolff Gmbh & Co. Kg Arzneimittel | Tripeptydy przeciwzapalne |
SG11201603440SA (en) | 2013-11-07 | 2016-05-30 | Wolff August Gmbh & Co Kg Arzneimittel Dr | Storage stable lyophilized tripeptide formulations |
CN107349416A (zh) * | 2017-08-01 | 2017-11-17 | 中山大学 | 一种含三肽化合物的抗骨关节炎药物 |
US11629169B2 (en) * | 2017-09-15 | 2023-04-18 | Kine Sciences Co., Ltd. | Use of peptides as therapeutic agent for autoimmune diseases and bone diseases |
CN111150831B (zh) * | 2020-02-27 | 2023-06-09 | 广州领晟医疗科技有限公司 | 多肽KdPT的应用 |
US11793746B2 (en) * | 2020-10-01 | 2023-10-24 | Chanda Zaveri | Intense skin hydration systems and methods |
CN114432421B (zh) * | 2022-01-12 | 2024-04-12 | 广州领晟医疗科技有限公司 | 一种用于治疗急性肺损伤的KdPT多肽及其应用 |
CN114404562A (zh) * | 2022-01-17 | 2022-04-29 | 广州领晟医疗科技有限公司 | 一种用于治疗骨关节炎的KdPT多肽及其应用 |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988000833A2 (en) * | 1986-08-08 | 1988-02-11 | Board Of Regents, The University Of Texas System | Antipyretic and anti-inflammatory peptides |
US4966848A (en) * | 1988-02-08 | 1990-10-30 | The General Hospital Corporation | Isolation, purification, characterization, cloning and sequencing of N α-acetyltransferase |
IL89770A (en) | 1988-03-28 | 1994-12-29 | British Tech Group | Analgesic peptides and pharmaceutical compositions containing them and the process for the preparation of some such compounds |
ES2012532A6 (es) * | 1988-07-15 | 1990-04-01 | Cusi Lab | Un procedimiento para la preparacion de una solucion acuosa de b-metil-4-(2' -tienilcarbonil)fenilacetato de lisina para aplicacion topica oftalmica. |
DE3844046A1 (de) * | 1988-12-28 | 1990-07-05 | Hoerrmann Wilhelm | Arzneimittel, die isomere des hydroxylysins oder lysins enthalten |
US5223421A (en) * | 1989-10-25 | 1993-06-29 | The General Hospital Corporation | Identification of methionine Nα-acetyltransferase |
DK0513379T3 (da) * | 1990-11-30 | 1996-09-30 | Teijin Ltd | 2-Arylthiazolderivater og farmaceutisk præparat indeholdende sådanne |
BR9405661A (pt) * | 1993-01-22 | 1995-11-21 | Pfizer | Sal de lisina de 6-cloro-5-flúor-3-(2-tenoil)-2-oxindole-1-carboxamida |
GB9413935D0 (en) * | 1994-07-11 | 1994-08-31 | Peptech Uk Ltd | Use of maramyl peptide compounds |
GB9419011D0 (en) * | 1994-09-21 | 1994-11-09 | Peptech Uk Ltd | Use of muramyl peptide compounds |
SE9500270L (sv) * | 1995-01-25 | 1996-09-09 | A K J Medi Konsult Ab | Läkemedel mot bristtillstånd |
AU4861196A (en) * | 1995-02-03 | 1996-08-21 | Cosmederm Technologies | Formulations and methods for reducing skin irritation |
FR2733421B1 (fr) | 1995-04-28 | 1997-06-06 | Oreal | Utilisation de derives de l'hormone stimulatrice des melanocytes de type alpha pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute |
US5688489A (en) * | 1995-09-15 | 1997-11-18 | Resolution Pharmaceuticals, Inc. | Non-receptor mediated imaging agents |
US5939394A (en) * | 1996-01-18 | 1999-08-17 | Fleming & Company | Methods and compositions for the prevention and treatment of immunological disorders, inflammatory diseases and infections |
JP3567350B2 (ja) * | 1996-03-13 | 2004-09-22 | 株式会社ホーネンコーポレーション | 抗脱毛症剤 |
JP3922594B2 (ja) | 1996-03-19 | 2007-05-30 | 株式会社ノエビア | 抗菌性低刺激化粧料 |
CA2256669A1 (en) * | 1996-05-29 | 1997-12-04 | Prototek, Inc. | Prodrugs of thalidomide and methods for using same as modulators of t-cell function |
US6117896A (en) * | 1997-02-10 | 2000-09-12 | Molecumetics Ltd. | Methods for regulating transcription factors |
JP4382880B2 (ja) * | 1996-10-11 | 2009-12-16 | 興和株式会社 | 新規なジアミド化合物及びこれを含有する医薬 |
AUPO713297A0 (en) * | 1997-06-02 | 1997-06-26 | Fujisawa Pharmaceutical Co., Ltd. | Oxazole compound |
SE9801571D0 (sv) * | 1998-05-05 | 1998-05-05 | Wapharm Ab | Melanokortin-1-receptorselektiva föreningar |
FR2784028B1 (fr) * | 1998-10-01 | 2003-02-07 | Oreal | Utilisation d'un peptide prevenant les reactions d'intolerance de la peau, notamment dans des compositions cosmetiques |
JP3962166B2 (ja) * | 1998-10-19 | 2007-08-22 | 株式会社資生堂 | 皮膚外用剤 |
AU1773600A (en) * | 1998-12-21 | 2000-07-12 | Aps Kbus 8 Nr. 4788 | Topical treatment of skin disease |
EP1150570B1 (en) * | 1999-01-22 | 2006-07-12 | The Schepens Eye Research Institute, Inc. | Activation of regulatory t cells by alpha-melanocyte stimulating hormone |
WO2000054750A1 (fr) * | 1999-03-15 | 2000-09-21 | Dmitry Anatolievich Starchenko | Procede de correction des perturbations dans la synthese du collagene et substance bioactive de mise en oeuvre de ce procede |
AU2001275930B2 (en) * | 2000-07-14 | 2007-05-10 | Eisai Inc. | Alpha-msh related compounds and methods of use |
DE10106852A1 (de) | 2001-02-14 | 2002-09-05 | T Luger | Entzündungshemmende Verbindungen |
WO2002092810A1 (fr) | 2001-05-11 | 2002-11-21 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Peptides presentant une activite inhibitrice de cyotoxicite et procede de balayage de ces peptides |
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2001
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2002
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2006
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