CY1114024T1 - Ενωσεις που αναστελλουν τη φλεγμονη - Google Patents

Ενωσεις που αναστελλουν τη φλεγμονη

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Publication number
CY1114024T1
CY1114024T1 CY20131100431T CY131100431T CY1114024T1 CY 1114024 T1 CY1114024 T1 CY 1114024T1 CY 20131100431 T CY20131100431 T CY 20131100431T CY 131100431 T CY131100431 T CY 131100431T CY 1114024 T1 CY1114024 T1 CY 1114024T1
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CY
Cyprus
Prior art keywords
compounds
against inflammation
pro
group
thr
Prior art date
Application number
CY20131100431T
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English (en)
Inventor
Thomas Luger
Original Assignee
Thomas Luger
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Thomas Luger filed Critical Thomas Luger
Publication of CY1114024T1 publication Critical patent/CY1114024T1/el

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/85—Hormones derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C12N2501/86—Melanocyte-stimulating hormone [MSH]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Transplantation (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Otolaryngology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Η παρούσα εφεύρεση αφορά τη χρησιμοποίηση μιας ένωσης του τύπου Lys-X, όπου X είναι μια υδροξυλομάδα, μια αμινομάδα, μια αλκοξυ-ομάδα, Pro ή Pro-Thr, ή ένα από φαρμακευτικής άποψης συμβατό άλας αυτών, για τη θεραπευτική αγωγή φλεγμονωδών ασθενειών των αγγείων.
CY20131100431T 2001-02-14 2013-05-30 Ενωσεις που αναστελλουν τη φλεγμονη CY1114024T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10106852A DE10106852A1 (de) 2001-02-14 2001-02-14 Entzündungshemmende Verbindungen
EP10154643.0A EP2198723B1 (de) 2001-02-14 2002-02-08 Entzündungshemmende Verbindungen

Publications (1)

Publication Number Publication Date
CY1114024T1 true CY1114024T1 (el) 2016-07-27

Family

ID=7674019

Family Applications (4)

Application Number Title Priority Date Filing Date
CY20071100596T CY1106563T1 (el) 2001-02-14 2007-05-07 Φλεγμονο-ανασταλτικες ενωσεις
CY20111100430T CY1111450T1 (el) 2001-02-14 2011-05-04 Ενωσεις που αναστελλουν τη φλεγμονη
CY20131100431T CY1114024T1 (el) 2001-02-14 2013-05-30 Ενωσεις που αναστελλουν τη φλεγμονη
CY20131100702T CY1114214T1 (el) 2001-02-14 2013-08-14 Lys-Pro-Thr KAI Lys-Pro ΩΣ ΕΝΩΣΕΙΣ ΠΟΥ ΑΝΑΣΤΕΛΛΟΥΝ ΤΗ ΦΛΕΓΜΟΝΗ

Family Applications Before (2)

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CY20071100596T CY1106563T1 (el) 2001-02-14 2007-05-07 Φλεγμονο-ανασταλτικες ενωσεις
CY20111100430T CY1111450T1 (el) 2001-02-14 2011-05-04 Ενωσεις που αναστελλουν τη φλεγμονη

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CY20131100702T CY1114214T1 (el) 2001-02-14 2013-08-14 Lys-Pro-Thr KAI Lys-Pro ΩΣ ΕΝΩΣΕΙΣ ΠΟΥ ΑΝΑΣΤΕΛΛΟΥΝ ΤΗ ΦΛΕΓΜΟΝΗ

Country Status (18)

Country Link
US (4) US8003608B2 (el)
EP (6) EP2189156A1 (el)
JP (1) JP4259870B2 (el)
CN (3) CN1269477C (el)
AT (2) ATE502632T1 (el)
AU (2) AU2002253000B2 (el)
CA (1) CA2437788C (el)
CY (4) CY1106563T1 (el)
DE (3) DE10106852A1 (el)
DK (4) DK2196202T3 (el)
ES (4) ES2281511T3 (el)
HK (4) HK1140960A1 (el)
MX (1) MXPA03007255A (el)
NZ (2) NZ542406A (el)
PL (3) PL221492B1 (el)
PT (4) PT1427405E (el)
SI (4) SI1749524T1 (el)
WO (1) WO2002064131A2 (el)

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EP2196202A1 (de) 2010-06-16
DK1427405T3 (da) 2007-07-02
PL223478B1 (pl) 2016-10-31
US9550807B2 (en) 2017-01-24
HK1140915A1 (en) 2010-10-29
HK1140960A1 (en) 2010-10-29
DE10106852A1 (de) 2002-09-05
US20170087202A1 (en) 2017-03-30
DE50214981D1 (de) 2011-05-05
CN1541095A (zh) 2004-10-27
EP1749524A3 (de) 2007-11-28
EP2189156A1 (de) 2010-05-26
US10046020B2 (en) 2018-08-14
AU2002253000B2 (en) 2006-05-25
EP2196202B1 (de) 2013-07-17
PT2198723E (pt) 2013-06-12
CN101215544A (zh) 2008-07-09
CY1106563T1 (el) 2012-01-25
EP1749524A2 (de) 2007-02-07
ES2411935T3 (es) 2013-07-09
CY1111450T1 (el) 2015-08-05
US20120045462A1 (en) 2012-02-23
ES2361422T3 (es) 2011-06-16
EP1427405A2 (de) 2004-06-16
SI2196202T1 (sl) 2013-09-30
WO2002064131A3 (de) 2004-04-01
CY1114214T1 (el) 2016-08-31
PT2196202E (pt) 2013-09-24
NZ542406A (en) 2007-04-27
MXPA03007255A (es) 2005-02-14
PL391988A1 (pl) 2010-09-13
US8846617B2 (en) 2014-09-30
CA2437788A1 (en) 2002-08-22
DE50209873D1 (de) 2007-05-16
PL391884A1 (pl) 2010-09-13
EP2198723A1 (de) 2010-06-23
ATE358475T1 (de) 2007-04-15
NZ528191A (en) 2005-11-25
PL369526A1 (en) 2005-05-02
EP1427405B1 (de) 2007-04-04
AU2006203622B2 (en) 2007-08-09
SI1427405T1 (sl) 2007-08-31
US20040077552A1 (en) 2004-04-22
AU2006203622A1 (en) 2006-09-07
SI2198723T1 (sl) 2013-06-28
US20150087578A1 (en) 2015-03-26
EP2260843A3 (de) 2011-08-03
EP2260843A2 (de) 2010-12-15
EP1749524B1 (de) 2011-03-23
DK1749524T3 (da) 2011-06-06
CN101810847B (zh) 2013-02-13
CN101810847A (zh) 2010-08-25
PT1749524E (pt) 2011-05-25
JP4259870B2 (ja) 2009-04-30
PL221492B1 (pl) 2016-04-29
SI1749524T1 (sl) 2011-08-31
PT1427405E (pt) 2007-05-31
DK2198723T3 (da) 2013-06-17
DK2196202T3 (da) 2013-09-08
ATE502632T1 (de) 2011-04-15
JP2004533995A (ja) 2004-11-11
CN1269477C (zh) 2006-08-16
PL223229B1 (pl) 2016-10-31
ES2281511T3 (es) 2007-10-01
ES2427970T3 (es) 2013-11-05
WO2002064131A2 (de) 2002-08-22
CA2437788C (en) 2011-04-05
US8003608B2 (en) 2011-08-23
HK1095538A1 (en) 2007-05-11
EP2198723B1 (de) 2013-04-10
HK1061980A1 (en) 2004-12-10
CN101215544B (zh) 2011-05-04

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