CY1107311T1 - Καμπτοθεκινες με εναν τροποποιημενο λακτονικο δακτυλιο - Google Patents
Καμπτοθεκινες με εναν τροποποιημενο λακτονικο δακτυλιοInfo
- Publication number
- CY1107311T1 CY1107311T1 CY20061101648T CY061101648T CY1107311T1 CY 1107311 T1 CY1107311 T1 CY 1107311T1 CY 20061101648 T CY20061101648 T CY 20061101648T CY 061101648 T CY061101648 T CY 061101648T CY 1107311 T1 CY1107311 T1 CY 1107311T1
- Authority
- CY
- Cyprus
- Prior art keywords
- campaigns
- modified
- lacton
- ring
- lacton ring
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 229940123780 DNA topoisomerase I inhibitor Drugs 0.000 abstract 1
- 239000000365 Topoisomerase I Inhibitor Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2002RM000305A ITRM20020305A1 (it) | 2002-05-31 | 2002-05-31 | Camptotecine con anello lattonico modificato. |
| EP03730480A EP1511752B3 (en) | 2002-05-31 | 2003-05-28 | Camptothecins with a modified lactone ring |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1107311T1 true CY1107311T1 (el) | 2012-11-21 |
Family
ID=11456338
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20061101648T CY1107311T1 (el) | 2002-05-31 | 2006-11-14 | Καμπτοθεκινες με εναν τροποποιημενο λακτονικο δακτυλιο |
| CY20081101240T CY1108793T1 (el) | 2002-05-31 | 2008-10-31 | Καμπτοθεκινες με τροποποιημενο λακτονικο δακτυλιο |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20081101240T CY1108793T1 (el) | 2002-05-31 | 2008-10-31 | Καμπτοθεκινες με τροποποιημενο λακτονικο δακτυλιο |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7273873B2 (https=) |
| EP (2) | EP1719775B1 (https=) |
| JP (1) | JP4693410B2 (https=) |
| KR (1) | KR101042042B1 (https=) |
| CN (1) | CN1656100A (https=) |
| AR (1) | AR040139A1 (https=) |
| AT (2) | ATE403659T1 (https=) |
| AU (2) | AU2003241160B2 (https=) |
| BR (2) | BR0311333A (https=) |
| CA (2) | CA2485201C (https=) |
| CY (2) | CY1107311T1 (https=) |
| DE (2) | DE60322754D1 (https=) |
| DK (2) | DK1719775T3 (https=) |
| ES (2) | ES2273002T7 (https=) |
| IT (1) | ITRM20020305A1 (https=) |
| MX (1) | MXPA04011682A (https=) |
| PE (1) | PE20050120A1 (https=) |
| PL (1) | PL374346A1 (https=) |
| PT (2) | PT1719775E (https=) |
| SI (2) | SI1511752T1 (https=) |
| TW (1) | TWI325866B (https=) |
| WO (1) | WO2003101995A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2852606A1 (fr) * | 2003-03-18 | 2004-09-24 | Inst Nat Sante Rech Med | Moyens pour inhiber simultanement l'expression de plusieurs genes impliques dans une pathologie |
| ITRM20030344A1 (it) * | 2003-07-14 | 2005-01-15 | Ist Naz Stud Cura Dei Tumori | 7-n-poliamminoalchil(ossi)imminometilcamptotecine recanti gruppi protettivi. |
| PT2170900E (pt) | 2007-08-01 | 2013-01-24 | Sigma Tau Ind Farmaceuti | Forma cristalina ii de 7-(dimetoximetil)-camptotecina, sua utilização como intermediário e produtos obtidos a partir dela |
| CN102746314B (zh) * | 2011-04-18 | 2016-07-06 | 华东师范大学 | 含有稳定7元内酯环的喜树碱类化合物、制备方法和用途 |
| CN104530066A (zh) * | 2015-01-06 | 2015-04-22 | 华东师范大学 | 一类新型高喜树碱衍生物、制备方法和用途 |
| CA3099155A1 (en) | 2018-05-14 | 2019-11-21 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| CA3138197A1 (en) | 2019-05-14 | 2020-11-19 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| EP4058464A1 (en) | 2019-11-13 | 2022-09-21 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| MX2023011241A (es) | 2021-03-23 | 2023-10-03 | Nuvation Bio Inc | Compuestos dirigidos a receptores de hormonas nucleares contra el cancer. |
| JP2024516024A (ja) | 2021-05-03 | 2024-04-11 | ニューベイション・バイオ・インコーポレイテッド | 抗がん核内ホルモン受容体標的化化合物 |
| WO2024073626A2 (en) * | 2022-09-28 | 2024-04-04 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57116076A (en) * | 1981-01-09 | 1982-07-19 | Yakult Honsha Co Ltd | Novel camptothecin derivative and its preparation |
| US4399276A (en) * | 1981-01-09 | 1983-08-16 | Kabushiki Kaisha Yakult Honsha | 7-Substituted camptothecin derivatives |
| FR2532591A1 (fr) | 1982-09-02 | 1984-03-09 | Hutchinson | Nouveau dispositif de securite pour pneumatiques de vehicules ou autres engins |
| DE69623961T2 (de) * | 1995-06-21 | 2003-05-08 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.), Paris | Camptothecinanaloge, verfahren zur ihrer herstellung, ihre verwendungals arzneimittel und diese enthaltende pharmazeutische zusammenfassungen |
| EP1044977B1 (en) | 1999-03-09 | 2002-05-02 | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. | Camptothecin derivatives having antitumor activity |
-
2002
- 2002-05-31 IT IT2002RM000305A patent/ITRM20020305A1/it unknown
-
2003
- 2003-05-26 TW TW092114164A patent/TWI325866B/zh not_active IP Right Cessation
- 2003-05-28 DK DK06116366T patent/DK1719775T3/da active
- 2003-05-28 BR BR0311333-7A patent/BR0311333A/pt not_active IP Right Cessation
- 2003-05-28 AT AT06116366T patent/ATE403659T1/de active
- 2003-05-28 CA CA2485201A patent/CA2485201C/en not_active Expired - Fee Related
- 2003-05-28 DK DK03730480.5T patent/DK1511752T5/da active
- 2003-05-28 ES ES03730480T patent/ES2273002T7/es active Active
- 2003-05-28 DE DE60322754T patent/DE60322754D1/de not_active Expired - Lifetime
- 2003-05-28 US US10/511,724 patent/US7273873B2/en not_active Expired - Fee Related
- 2003-05-28 AT AT03730480T patent/ATE339422T1/de active
- 2003-05-28 PT PT06116366T patent/PT1719775E/pt unknown
- 2003-05-28 WO PCT/IT2003/000328 patent/WO2003101995A2/en not_active Ceased
- 2003-05-28 DE DE60308368T patent/DE60308368T3/de not_active Expired - Lifetime
- 2003-05-28 BR BR0311329-9A patent/BR0311329A/pt not_active IP Right Cessation
- 2003-05-28 EP EP06116366A patent/EP1719775B1/en not_active Expired - Lifetime
- 2003-05-28 EP EP03730480A patent/EP1511752B3/en not_active Expired - Lifetime
- 2003-05-28 MX MXPA04011682A patent/MXPA04011682A/es active IP Right Grant
- 2003-05-28 PL PL03374346A patent/PL374346A1/xx unknown
- 2003-05-28 CA CA2706635A patent/CA2706635A1/en not_active Abandoned
- 2003-05-28 SI SI200330509T patent/SI1511752T1/sl unknown
- 2003-05-28 CN CNA038125439A patent/CN1656100A/zh active Pending
- 2003-05-28 KR KR1020047016880A patent/KR101042042B1/ko not_active Expired - Fee Related
- 2003-05-28 JP JP2004509686A patent/JP4693410B2/ja not_active Expired - Fee Related
- 2003-05-28 ES ES06116366T patent/ES2312090T3/es not_active Expired - Lifetime
- 2003-05-28 SI SI200331380T patent/SI1719775T1/sl unknown
- 2003-05-28 PT PT03730480T patent/PT1511752E/pt unknown
- 2003-05-28 AU AU2003241160A patent/AU2003241160B2/en not_active Ceased
- 2003-05-30 PE PE2003000529A patent/PE20050120A1/es not_active Application Discontinuation
- 2003-05-30 AR ARP030101915A patent/AR040139A1/es unknown
-
2006
- 2006-11-14 CY CY20061101648T patent/CY1107311T1/el unknown
-
2008
- 2008-10-31 CY CY20081101240T patent/CY1108793T1/el unknown
-
2009
- 2009-11-12 AU AU2009236044A patent/AU2009236044B8/en not_active Ceased
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1108793T1 (el) | Καμπτοθεκινες με τροποποιημενο λακτονικο δακτυλιο | |
| CY1109581T1 (el) | Εστερες στη θεση 20 των καμπτοθεκινων | |
| CY1106130T1 (el) | Παραγωγα 2-πυριδονης ως αναστολεις της ουδετepοφιλης ελαστασης | |
| CY1112941T1 (el) | Δικυκλικοι αναστολεις της μεκ | |
| CY1108456T1 (el) | Ενωσεις βενζιμιδαζολονης | |
| ATE302775T1 (de) | Carbolinderivate | |
| CY1108454T1 (el) | Ενωσεις σπειροπυραζολιου | |
| TR200100432T2 (tr) | Hepatit C inhibitörü tri-peptidler | |
| CY1108874T1 (el) | ΧΡΗΣΗ ΤΩΝ ΑΝΑΣΤΟΛΕΩΝ Ι κΒ- ΚΙΝΑΣΗΣ ΣΤΗ ΘΕΡΑΠΕΙΑ ΤΟΥ ΠΟΝΟΥ | |
| UY26886A1 (es) | Polimorfos de un análogo de epotilona | |
| CY1110521T1 (el) | Υποκατεστημενα ινδολια για τη διαμορφωση της nfkb-ενεργοτητας | |
| SI2151250T1 (sl) | Z vitamini ciljana sredstva za slikanje | |
| CY1115249T1 (el) | Συνθεση εις τη φυση απαντωσων εκτεϊνασκιδινων και σχετικων ενωσεων | |
| CY1117221T1 (el) | Παραγωγα αζα σπειρο αλκανιου ως αναστολεις μεταλλοπρωτεασων | |
| DK0931788T3 (da) | Metalloproteasehæmmere | |
| CY1108707T1 (el) | Αναλογα νοσισεπτινης | |
| FI924458A0 (fi) | Mono-fluoriderade derivat av n-propargyl-1-amonoindan och deras anvaendning foer inhibering av monoaminoxidas | |
| CY1107149T1 (el) | Νεα παραγωγα αμιδινοβενζυλαμινης και χρηση τους ως αναστολεων θρομβινης | |
| CY1106358T1 (el) | Νεοι δικυκλικοι αναστολεις της ορμονοευαισθητης λιπασης | |
| PA8577001A1 (es) | Benzoilureas heterociclicamente sustituidas, procedimiento para su preparacion y su uso como farmacos | |
| ATE325604T1 (de) | Oral verabreichbare zusammensetzung zum schutz der haut vor licht | |
| DE602004024770D1 (de) | Substituierte 8-perfluoro-6,7,8,9-tetrahydropyrimido-(1,2a) pyrimidin-4-on derivate | |
| CY1106957T1 (el) | Ν-σουλφονυλο-4-μεθυλεναμινο-3-υδροξυ-2-πυριδονες ως αντιμικροβιακοι παραγοντες | |
| CY1105047T1 (el) | Ενωσεις πυριδοπυριμιδινονης, η μεθοδος παρασκευης τους και φαρμακευτικες συνθεσεις που τις περιεχουν | |
| DK1313740T3 (da) | Prodrugs af imidazopyridinderivater |