UY26886A1 - Polimorfos de un análogo de epotilona - Google Patents

Polimorfos de un análogo de epotilona

Info

Publication number
UY26886A1
UY26886A1 UY26886A UY26886A UY26886A1 UY 26886 A1 UY26886 A1 UY 26886A1 UY 26886 A UY26886 A UY 26886A UY 26886 A UY26886 A UY 26886A UY 26886 A1 UY26886 A1 UY 26886A1
Authority
UY
Uruguay
Prior art keywords
epotilone
polymorphes
analog
methods
mixtures
Prior art date
Application number
UY26886A
Other languages
English (en)
Inventor
Zhenrong Guo
John D Dimarco
Jack Z Gougoutas
Imre M Vitez
Martha Davidovich
Michael Galolla
Timothy M Malloy
Denis Favreau
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22845469&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY26886(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of UY26886A1 publication Critical patent/UY26886A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Se proporcionan, de acuerdo con la presente invención, dos polímeros cristalinos, denominados forma A y forma B respectivamente, así como mezclas de los mismos, de un análogo de epotilona representado por la fórmula. También se proporcionan métodos para formar los polimorfos novedosos, métodos terapéuticos que los utilizan y formas de dosificación farmacéutica que los contienen.
UY26886A 2000-08-16 2001-08-15 Polimorfos de un análogo de epotilona UY26886A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22559000P 2000-08-16 2000-08-16

Publications (1)

Publication Number Publication Date
UY26886A1 true UY26886A1 (es) 2002-03-22

Family

ID=22845469

Family Applications (1)

Application Number Title Priority Date Filing Date
UY26886A UY26886A1 (es) 2000-08-16 2001-08-15 Polimorfos de un análogo de epotilona

Country Status (42)

Country Link
US (4) US6689802B2 (es)
EP (1) EP1309597B1 (es)
JP (1) JP5046467B2 (es)
KR (1) KR100810342B1 (es)
CN (1) CN1269821C (es)
AR (1) AR034259A1 (es)
AT (1) ATE366735T1 (es)
AU (2) AU2001281082B2 (es)
BG (1) BG66132B1 (es)
BR (1) BR0113234A (es)
CA (1) CA2418109C (es)
CY (1) CY1107758T1 (es)
CZ (1) CZ305523B6 (es)
DE (1) DE60129334T2 (es)
DK (1) DK1309597T3 (es)
EE (1) EE05273B1 (es)
ES (1) ES2288518T3 (es)
GE (1) GEP20053495B (es)
HK (1) HK1052010A1 (es)
HR (1) HRP20030190B1 (es)
HU (1) HU229314B1 (es)
IL (2) IL153993A0 (es)
IS (1) IS2845B (es)
LT (1) LT5138B (es)
LV (1) LV13032B (es)
MX (1) MXPA03001431A (es)
MY (1) MY134129A (es)
NO (1) NO328500B1 (es)
NZ (1) NZ523722A (es)
PE (1) PE20020290A1 (es)
PL (1) PL205628B1 (es)
PT (1) PT1309597E (es)
RO (1) RO123296B1 (es)
RU (1) RU2272039C2 (es)
SI (1) SI21100B (es)
SK (1) SK287876B6 (es)
TW (1) TWI320040B (es)
UA (1) UA75365C2 (es)
UY (1) UY26886A1 (es)
WO (1) WO2002014323A2 (es)
YU (1) YU12103A (es)
ZA (1) ZA200300522B (es)

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MXPA03007394A (es) 2001-02-20 2003-12-04 Bristol Myers Squibb Co Tratamiento de tumores refractarios mediante uso de derivados de epotilona.
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Also Published As

Publication number Publication date
AR034259A1 (es) 2004-02-18
WO2002014323A2 (en) 2002-02-21
PT1309597E (pt) 2007-08-22
PE20020290A1 (es) 2002-04-03
HU229314B1 (en) 2013-10-28
HUP0300826A2 (hu) 2003-09-29
US20060063815A1 (en) 2006-03-23
DK1309597T3 (da) 2007-10-22
IL153993A (en) 2009-07-20
HRP20030190A2 (en) 2003-04-30
YU12103A (sh) 2006-08-17
US6689802B2 (en) 2004-02-10
EP1309597B1 (en) 2007-07-11
HK1052010A1 (en) 2003-08-29
KR20030022411A (ko) 2003-03-15
LT2003017A (en) 2004-03-25
US20020188014A1 (en) 2002-12-12
SI21100A (sl) 2003-06-30
IS2845B (is) 2013-08-15
IL153993A0 (en) 2003-07-31
UA75365C2 (en) 2006-04-17
SK1342003A3 (en) 2003-09-11
CZ305523B6 (cs) 2015-11-18
KR100810342B1 (ko) 2008-03-07
CN1468243A (zh) 2004-01-14
BR0113234A (pt) 2004-02-25
CN1269821C (zh) 2006-08-16
BG66132B1 (bg) 2011-06-30
MY134129A (en) 2007-11-30
BG107467A (bg) 2003-09-30
JP5046467B2 (ja) 2012-10-10
PL365610A1 (en) 2005-01-10
NO328500B1 (no) 2010-03-01
USRE39251E1 (en) 2006-08-29
ZA200300522B (en) 2004-04-20
HUP0300826A3 (en) 2005-05-30
CA2418109C (en) 2011-09-27
IS6714A (is) 2003-02-11
AU2001281082B2 (en) 2007-01-04
EE05273B1 (et) 2010-02-15
MXPA03001431A (es) 2004-05-04
ATE366735T1 (de) 2007-08-15
DE60129334D1 (en) 2007-08-23
NZ523722A (en) 2005-04-29
SI21100B (sl) 2009-12-31
AU8108201A (en) 2002-02-25
SK287876B6 (sk) 2012-02-03
US7153879B2 (en) 2006-12-26
PL205628B1 (pl) 2010-05-31
RU2272039C2 (ru) 2006-03-20
DE60129334T2 (de) 2008-04-03
LV13032B (en) 2003-12-20
CZ2003418A3 (cs) 2004-01-14
US6982276B2 (en) 2006-01-03
JP2004506638A (ja) 2004-03-04
US20040157897A1 (en) 2004-08-12
GEP20053495B (en) 2005-04-25
WO2002014323A3 (en) 2002-05-02
CA2418109A1 (en) 2002-02-21
EE200300063A (et) 2004-12-15
RO123296B1 (ro) 2011-06-30
ES2288518T3 (es) 2008-01-16
TWI320040B (en) 2010-02-01
CY1107758T1 (el) 2013-06-19
NO20030707L (no) 2003-04-15
EP1309597A2 (en) 2003-05-14
HRP20030190B1 (en) 2011-07-31
NO20030707D0 (no) 2003-02-14
LT5138B (lt) 2004-06-25

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