CY1108793T1 - Καμπτοθεκινες με τροποποιημενο λακτονικο δακτυλιο - Google Patents
Καμπτοθεκινες με τροποποιημενο λακτονικο δακτυλιοInfo
- Publication number
- CY1108793T1 CY1108793T1 CY20081101240T CY081101240T CY1108793T1 CY 1108793 T1 CY1108793 T1 CY 1108793T1 CY 20081101240 T CY20081101240 T CY 20081101240T CY 081101240 T CY081101240 T CY 081101240T CY 1108793 T1 CY1108793 T1 CY 1108793T1
- Authority
- CY
- Cyprus
- Prior art keywords
- campaigns
- modified
- lacton
- ring
- lacton ring
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Epoxy Compounds (AREA)
Abstract
Περιγράφονται ενώσεις του τύπου (Ι) ή (II) : όπου οι ομάδες είναι όπως ορίζονται στην πιο κάτω περιγραφή, τα ρακεμικά μείγματα, τα ξεχωριστά εναντιομερή τους, τα ξεχωριστά διαστερεοϊσομερή τους, τα μείγματα τους, και τα φαρμακευτικά αποδεκτά άλατα τους. Οι εν λόγω ενώσεις είναι αναστολείς τοποϊσομεράσης Ι.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2002RM000305A ITRM20020305A1 (it) | 2002-05-31 | 2002-05-31 | Camptotecine con anello lattonico modificato. |
| EP06116366A EP1719775B1 (en) | 2002-05-31 | 2003-05-28 | Camptothecins with a modified lactone ring |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1108793T1 true CY1108793T1 (el) | 2014-04-09 |
Family
ID=11456338
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20061101648T CY1107311T1 (el) | 2002-05-31 | 2006-11-14 | Καμπτοθεκινες με εναν τροποποιημενο λακτονικο δακτυλιο |
| CY20081101240T CY1108793T1 (el) | 2002-05-31 | 2008-10-31 | Καμπτοθεκινες με τροποποιημενο λακτονικο δακτυλιο |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20061101648T CY1107311T1 (el) | 2002-05-31 | 2006-11-14 | Καμπτοθεκινες με εναν τροποποιημενο λακτονικο δακτυλιο |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7273873B2 (el) |
| EP (2) | EP1719775B1 (el) |
| JP (1) | JP4693410B2 (el) |
| KR (1) | KR101042042B1 (el) |
| CN (1) | CN1656100A (el) |
| AR (1) | AR040139A1 (el) |
| AT (2) | ATE403659T1 (el) |
| AU (2) | AU2003241160B2 (el) |
| BR (2) | BR0311333A (el) |
| CA (2) | CA2706635A1 (el) |
| CY (2) | CY1107311T1 (el) |
| DE (2) | DE60322754D1 (el) |
| DK (2) | DK1719775T3 (el) |
| ES (2) | ES2273002T7 (el) |
| IT (1) | ITRM20020305A1 (el) |
| MX (1) | MXPA04011682A (el) |
| PE (1) | PE20050120A1 (el) |
| PL (1) | PL374346A1 (el) |
| PT (2) | PT1511752E (el) |
| SI (2) | SI1719775T1 (el) |
| TW (1) | TWI325866B (el) |
| WO (1) | WO2003101995A2 (el) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2852606A1 (fr) * | 2003-03-18 | 2004-09-24 | Inst Nat Sante Rech Med | Moyens pour inhiber simultanement l'expression de plusieurs genes impliques dans une pathologie |
| ITRM20030344A1 (it) | 2003-07-14 | 2005-01-15 | Ist Naz Stud Cura Dei Tumori | 7-n-poliamminoalchil(ossi)imminometilcamptotecine recanti gruppi protettivi. |
| EP2170900B1 (en) | 2007-08-01 | 2012-12-12 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Crystalline form ii of 7-(dimethoxy-methyl) camptothecin, its use as intermediate and products obtained therefrom |
| CN102746314B (zh) * | 2011-04-18 | 2016-07-06 | 华东师范大学 | 含有稳定7元内酯环的喜树碱类化合物、制备方法和用途 |
| CN104530066A (zh) * | 2015-01-06 | 2015-04-22 | 华东师范大学 | 一类新型高喜树碱衍生物、制备方法和用途 |
| CA3138197A1 (en) | 2019-05-14 | 2020-11-19 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| US11952349B2 (en) | 2019-11-13 | 2024-04-09 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| IL306010A (en) * | 2021-03-23 | 2023-11-01 | Nuvation Bio Inc | Anticancer compounds against the nuclear hormone receptor |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57116076A (en) * | 1981-01-09 | 1982-07-19 | Yakult Honsha Co Ltd | Novel camptothecin derivative and its preparation |
| US4399276A (en) * | 1981-01-09 | 1983-08-16 | Kabushiki Kaisha Yakult Honsha | 7-Substituted camptothecin derivatives |
| FR2532591A1 (fr) | 1982-09-02 | 1984-03-09 | Hutchinson | Nouveau dispositif de securite pour pneumatiques de vehicules ou autres engins |
| PL185354B1 (pl) * | 1995-06-21 | 2003-04-30 | Sod Conseils Rech Applic | Nowe analogi kamptotecyny, sposoby ich wytwarzania, ich zastosowanie jako leków oraz zawierające je kompozycje farmaceutyczne |
| SI1044977T1 (en) * | 1999-03-09 | 2002-08-31 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Camptothecin derivatives having antitumor activity |
-
2002
- 2002-05-31 IT IT2002RM000305A patent/ITRM20020305A1/it unknown
-
2003
- 2003-05-26 TW TW092114164A patent/TWI325866B/zh not_active IP Right Cessation
- 2003-05-28 BR BR0311333-7A patent/BR0311333A/pt not_active IP Right Cessation
- 2003-05-28 AU AU2003241160A patent/AU2003241160B2/en not_active Ceased
- 2003-05-28 DK DK06116366T patent/DK1719775T3/da active
- 2003-05-28 JP JP2004509686A patent/JP4693410B2/ja not_active Expired - Fee Related
- 2003-05-28 SI SI200331380T patent/SI1719775T1/sl unknown
- 2003-05-28 PL PL03374346A patent/PL374346A1/xx unknown
- 2003-05-28 PT PT03730480T patent/PT1511752E/pt unknown
- 2003-05-28 PT PT06116366T patent/PT1719775E/pt unknown
- 2003-05-28 CN CNA038125439A patent/CN1656100A/zh active Pending
- 2003-05-28 ES ES03730480T patent/ES2273002T7/es active Active
- 2003-05-28 AT AT06116366T patent/ATE403659T1/de active
- 2003-05-28 CA CA2706635A patent/CA2706635A1/en not_active Abandoned
- 2003-05-28 DK DK03730480.5T patent/DK1511752T5/da active
- 2003-05-28 WO PCT/IT2003/000328 patent/WO2003101995A2/en active IP Right Grant
- 2003-05-28 EP EP06116366A patent/EP1719775B1/en not_active Expired - Lifetime
- 2003-05-28 DE DE60322754T patent/DE60322754D1/de not_active Expired - Lifetime
- 2003-05-28 KR KR1020047016880A patent/KR101042042B1/ko not_active IP Right Cessation
- 2003-05-28 CA CA2485201A patent/CA2485201C/en not_active Expired - Fee Related
- 2003-05-28 SI SI200330509T patent/SI1511752T1/sl unknown
- 2003-05-28 DE DE60308368T patent/DE60308368T3/de not_active Expired - Lifetime
- 2003-05-28 MX MXPA04011682A patent/MXPA04011682A/es active IP Right Grant
- 2003-05-28 ES ES06116366T patent/ES2312090T3/es not_active Expired - Lifetime
- 2003-05-28 US US10/511,724 patent/US7273873B2/en not_active Expired - Fee Related
- 2003-05-28 AT AT03730480T patent/ATE339422T1/de active
- 2003-05-28 EP EP03730480A patent/EP1511752B3/en not_active Expired - Lifetime
- 2003-05-28 BR BR0311329-9A patent/BR0311329A/pt not_active IP Right Cessation
- 2003-05-30 AR ARP030101915A patent/AR040139A1/es unknown
- 2003-05-30 PE PE2003000529A patent/PE20050120A1/es not_active Application Discontinuation
-
2006
- 2006-11-14 CY CY20061101648T patent/CY1107311T1/el unknown
-
2008
- 2008-10-31 CY CY20081101240T patent/CY1108793T1/el unknown
-
2009
- 2009-11-12 AU AU2009236044A patent/AU2009236044B8/en not_active Ceased
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