CR6726A - Compuestos azapoliciclicos condensados con arilo - Google Patents
Compuestos azapoliciclicos condensados con ariloInfo
- Publication number
- CR6726A CR6726A CR6726A CR6726A CR6726A CR 6726 A CR6726 A CR 6726A CR 6726 A CR6726 A CR 6726A CR 6726 A CR6726 A CR 6726A CR 6726 A CR6726 A CR 6726A
- Authority
- CR
- Costa Rica
- Prior art keywords
- compounds
- azapoliciclic
- arilo
- compounds condensed
- condensed
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/24—Camphidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Anesthesiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Toxicology (AREA)
- Nutrition Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Consiste en compuestos de la formula I, y a sus sales farmaceuticamente aceptables, en la que R1, R2 y R3 son como se han definido en la presente, a intermedios para la sintesis de dichos compuestos, a composiciones farmaceuticas que contienen dichos compuestos y procedimientos de uso de dichos compuestos en el tratamiento de dolencias neurologicas y psicologicas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/514,002 US6605610B1 (en) | 1997-12-31 | 2000-02-25 | Aryl fused azapolycyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR6726A true CR6726A (es) | 2003-10-28 |
Family
ID=24045406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR6726A CR6726A (es) | 2000-02-25 | 2002-08-09 | Compuestos azapoliciclicos condensados con arilo |
Country Status (40)
| Country | Link |
|---|---|
| US (3) | US6605610B1 (es) |
| EP (2) | EP1259489B1 (es) |
| JP (1) | JP2003524002A (es) |
| KR (1) | KR100537976B1 (es) |
| CN (1) | CN1263745C (es) |
| AP (1) | AP1860A (es) |
| AT (2) | ATE453643T1 (es) |
| AU (2) | AU784081B2 (es) |
| BG (1) | BG65891B1 (es) |
| BR (1) | BR0108610A (es) |
| CA (1) | CA2401229C (es) |
| CR (1) | CR6726A (es) |
| CU (1) | CU23148A3 (es) |
| CY (1) | CY1105301T1 (es) |
| CZ (1) | CZ303203B6 (es) |
| DE (2) | DE60140965D1 (es) |
| DK (2) | DK1259489T3 (es) |
| DZ (1) | DZ3328A1 (es) |
| EA (1) | EA005316B1 (es) |
| EE (1) | EE200200475A (es) |
| ES (2) | ES2336800T3 (es) |
| GE (1) | GEP20053454B (es) |
| HK (1) | HK1050894A1 (es) |
| HR (1) | HRP20020700A2 (es) |
| HU (1) | HU229482B1 (es) |
| IL (2) | IL150639A0 (es) |
| IS (1) | IS2293B (es) |
| MA (1) | MA26875A1 (es) |
| MX (1) | MXPA02008311A (es) |
| NO (1) | NO323608B1 (es) |
| NZ (1) | NZ519973A (es) |
| OA (1) | OA12181A (es) |
| PL (1) | PL365163A1 (es) |
| PT (1) | PT1259489E (es) |
| RS (1) | RS51123B (es) |
| SI (1) | SI1259489T1 (es) |
| SK (1) | SK12042002A3 (es) |
| UA (1) | UA74813C2 (es) |
| WO (1) | WO2001062736A1 (es) |
| ZA (1) | ZA200206768B (es) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2301210T5 (es) * | 1997-12-31 | 2015-05-07 | Pfizer Products Inc. | Compuestos azapolicíclicos condensados con un arilo |
| IL157881A0 (en) * | 2001-04-20 | 2004-03-28 | Pfizer Prod Inc | Process for the preparation of 1,3-substituted indenes and aryl-fused azapolycyclic compounds |
| WO2003037329A1 (en) * | 2001-10-31 | 2003-05-08 | Pfizer Products Inc. | Nicotinic acetylcholine receptor agonists in the treatment of restless legs syndrome |
| DE60228478D1 (de) * | 2001-11-30 | 2008-10-02 | Pfizer Prod Inc | Aryl-annellierte azapolyzyklische verbindungen |
| IL161857A0 (en) * | 2001-11-30 | 2005-11-20 | Pfizer Prod Inc | Pharmaceutical compositions of 5,7,14-triazatetracycloÄ10.3.1.0(2,11).0(4,9)Ü-hexadeca-2(11)3,5,7,9-pentaene |
| KR101228376B1 (ko) | 2002-07-18 | 2013-01-31 | 사이토스 바이오테크놀로지 아게 | 합텐-캐리어 컨쥬게이트 및 그의 용도 |
| EP1554041B1 (en) * | 2002-10-22 | 2012-05-23 | EMD Millipore Corporation | Multi-sided immersion formation of composite structures and method |
| PL377292A1 (pl) * | 2002-11-25 | 2006-01-23 | Pfizer Products Inc. | Ulepszony sposób wytwarzania 1,3-podstawionych indenów |
| RS20050513A (en) * | 2003-01-15 | 2007-11-15 | Pfizer Products Inc., | Process for the preparation of aryl fused polycyclic lactams |
| MXPA05012507A (es) * | 2003-05-20 | 2006-01-30 | Pfizer Prod Inc | Composiciones farmaceuticas de vareniclina. |
| JP2006526607A (ja) * | 2003-06-04 | 2006-11-24 | ファイザー・プロダクツ・インク | ２，３−ジヒドロキシ−１，４−ヂオキサンを用いたジアニリンからの置換キノキサリンの製造方法 |
| BRPI0412880A (pt) * | 2003-07-21 | 2006-10-03 | Pfizer Prod Inc | compostos azapolicìclicos fundidos a arila |
| US8580842B2 (en) * | 2003-09-30 | 2013-11-12 | Abbott Gmbh & Co. Kg | Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them |
| JP4308263B2 (ja) * | 2003-10-14 | 2009-08-05 | ゼノポート，インコーポレイティド | γ−アミノ酪酸アナログの結晶形 |
| CA2549638A1 (en) * | 2003-12-23 | 2005-07-14 | Pfizer Products Inc. | Therapeutic combination for cognition enhancement and psychotic disorders |
| WO2006006071A1 (en) * | 2004-07-07 | 2006-01-19 | Pfizer Products Inc. | Resolution of an aryl-fused azapolycyclic compound |
| US20080275051A1 (en) * | 2005-02-24 | 2008-11-06 | Busch Frank R | Preparation of High Purity Substituted Quinoxalines |
| RU2403016C2 (ru) * | 2006-04-24 | 2010-11-10 | Пфайзер Продактс Инк. | Асимметричные мембраны для устройств доставки лекарственного препарата |
| AU2007319951A1 (en) * | 2006-11-09 | 2008-05-22 | Pfizer Products Inc. | Polymorphs of nicotinic intermediates |
| US20080167286A1 (en) | 2006-12-12 | 2008-07-10 | Abbott Laboratories | Pharmaceutical compositions and their methods of use |
| US8486979B2 (en) * | 2006-12-12 | 2013-07-16 | Abbvie Inc. | 1,2,4 oxadiazole compounds and methods of use thereof |
| UY30846A1 (es) * | 2006-12-30 | 2008-07-31 | Abbott Gmbh & Amp | Derivados de oxindol sustituidos, medicamentos que los comprenden y uso de los mismos |
| US20090062257A1 (en) * | 2007-08-29 | 2009-03-05 | Protia, Llc | Deuterium-enriched varenicline |
| WO2009034431A2 (en) | 2007-09-10 | 2009-03-19 | Pfizer Inc. | Controlled-release dosage forms for varenicline |
| WO2009065872A2 (en) * | 2007-11-20 | 2009-05-28 | Medichem, S.A. | Improved processes for the synthesis of varenicline l-tartrate |
| US8703774B2 (en) | 2007-12-07 | 2014-04-22 | AbbVie Deutschland GmbH & Co. KG | Carbamate-substituted oxindole derivatives and use thereof for the treatment of vasopressin-dependent diseases |
| MX2010006202A (es) * | 2007-12-07 | 2011-03-04 | Abbott Gmbh & Co Kg | Derivados de oxindol substituidos por amidometil y el uso de los mismos para el tratamiento de enfermedades dependientes de la vasopresina. |
| CA2707671C (en) * | 2007-12-07 | 2016-02-02 | Abbott Gmbh & Co. Kg | 5,6-disubstituted oxindole-derivatives and use thereof for treating vasopressine-dependent diseases |
| CN101952276B (zh) * | 2007-12-07 | 2014-10-22 | Abbvie德国有限责任两合公司 | 5-卤素取代的羟吲哚衍生物和其用于治疗加压素依赖性疾病的用途 |
| US8383657B2 (en) | 2007-12-21 | 2013-02-26 | Abbott Laboratories | Thiazolylidine urea and amide derivatives and methods of use thereof |
| EP2271344A4 (en) | 2008-03-31 | 2011-04-27 | Univ South Florida | METHODS OF TREATING DISEASE INDUCED ATAXIA AND NON-ATAXIC IMBALANCE |
| CA2709774C (en) * | 2008-05-22 | 2012-10-02 | Teva Pharmaceutical Industries Ltd. | Varenicline tosylate, an intermediate in the preparation process of varenicline l-tartrate |
| US20090318695A1 (en) * | 2008-06-19 | 2009-12-24 | Vinod Kumar Kansal | Processes for the preparation of varenicline and intermediates thereof |
| WO2010005643A1 (en) * | 2008-07-10 | 2010-01-14 | Teva Pharmaceutical Industries Ltd. | Processes for purifying varenicline l-tartrate salt and preparing crystalline forms of varenicline l-tartrate salt |
| WO2010023561A1 (en) * | 2008-09-01 | 2010-03-04 | Actavis Group Ptc Ehf | Process for preparing varenicline, varenicline intermediates, and pharmaceutically acceptable salts thereof |
| EP2396327A1 (en) | 2009-02-11 | 2011-12-21 | Sunovion Pharmaceuticals Inc. | Histamine h3 inverse agonists and antagonists and methods of use thereof |
| EP2435080A2 (en) | 2009-05-29 | 2012-04-04 | Abbott Laboratories | Pharmaceutical compositions for the treatment of pain |
| EP2438054A1 (en) * | 2009-06-22 | 2012-04-11 | Teva Pharmaceutical Industries Ltd. | Solid states forms of varenicline salts and processes for preparation thereof |
| CN110381919A (zh) | 2017-03-03 | 2019-10-25 | 西梯茜生命工学股份有限公司 | 含有伐尼克兰或其药学上可接受的盐的包合复合物的口服施用制剂 |
| CN114929235A (zh) * | 2020-01-03 | 2022-08-19 | 布鲁奥科制药有限公司 | 用于治疗cns病症的化合物和组合物 |
| CN115322105A (zh) * | 2021-05-11 | 2022-11-11 | 江苏润安制药有限公司 | 一种合成艾拉莫德关键中间体的方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3471503A (en) | 1967-05-05 | 1969-10-07 | Mcneilab Inc | 1,2,3,5,6,7-hexahydro-4-phenethyl-2,6-methano-4h-4- benzazonin-12-ols |
| ES2301210T5 (es) * | 1997-12-31 | 2015-05-07 | Pfizer Products Inc. | Compuestos azapolicíclicos condensados con un arilo |
| EP0955301A3 (en) | 1998-04-27 | 2001-04-18 | Pfizer Products Inc. | 7-aza-bicyclo[2.2.1]-heptane derivatives, their preparation and use according to their affinity for neuronal nicotinic acetylcholine receptors |
| EA003669B1 (ru) | 1998-04-29 | 2003-08-28 | Пфайзер Продактс Инк. | Конденсированные с арилом азаполициклические соединения |
| CZ20012716A3 (cs) * | 1999-01-29 | 2001-11-14 | Abbott Laboratories | Diazabicyklické deriváty jako ligandy nikotinového receptoru acetylcholinu |
| FR2788982B1 (fr) * | 1999-02-02 | 2002-08-02 | Synthelabo | Compositions pharmaceutiques contenant de la nicotine et leur application dans le sevrage tabagique |
| IL137937A0 (en) * | 1999-08-27 | 2001-10-31 | Pfizer Prod Inc | A pharmaceutical composition for the prevention and treatment of nicotine addiction in a mammal |
| US6660741B2 (en) * | 2001-03-19 | 2003-12-09 | Sloan-Kettering Institute For Cancer Research | Asymmetric synthesis of (S,S,R)-(-)-actinonin and its analogs and uses therefor |
| BRPI0412880A (pt) * | 2003-07-21 | 2006-10-03 | Pfizer Prod Inc | compostos azapolicìclicos fundidos a arila |
| US8123947B2 (en) | 2007-10-22 | 2012-02-28 | Baxter International Inc. | Priming and air removal systems and methods for dialysis |
-
2000
- 2000-02-25 US US09/514,002 patent/US6605610B1/en not_active Expired - Fee Related
-
2001
- 2001-02-08 DZ DZ013328A patent/DZ3328A1/fr active
- 2001-02-08 DK DK01953630T patent/DK1259489T3/da active
- 2001-02-08 HU HU0204580A patent/HU229482B1/hu not_active IP Right Cessation
- 2001-02-08 WO PCT/IB2001/000153 patent/WO2001062736A1/en active IP Right Grant
- 2001-02-08 MX MXPA02008311A patent/MXPA02008311A/es active IP Right Grant
- 2001-02-08 PT PT01953630T patent/PT1259489E/pt unknown
- 2001-02-08 DE DE60140965T patent/DE60140965D1/de not_active Expired - Lifetime
- 2001-02-08 KR KR10-2002-7011140A patent/KR100537976B1/ko not_active IP Right Cessation
- 2001-02-08 PL PL01365163A patent/PL365163A1/xx not_active Application Discontinuation
- 2001-02-08 CN CNB018055737A patent/CN1263745C/zh not_active Expired - Fee Related
- 2001-02-08 OA OA1200200256A patent/OA12181A/en unknown
- 2001-02-08 EA EA200200716A patent/EA005316B1/ru not_active IP Right Cessation
- 2001-02-08 CZ CZ20022778A patent/CZ303203B6/cs not_active IP Right Cessation
- 2001-02-08 EE EEP200200475A patent/EE200200475A/xx unknown
- 2001-02-08 JP JP2001562518A patent/JP2003524002A/ja active Pending
- 2001-02-08 SI SI200130584T patent/SI1259489T1/sl unknown
- 2001-02-08 DK DK05106835.1T patent/DK1619192T3/da active
- 2001-02-08 AP APAP/P/2002/002604A patent/AP1860A/en active
- 2001-02-08 RS YUP-596/02A patent/RS51123B/sr unknown
- 2001-02-08 DE DE60120366T patent/DE60120366T2/de not_active Expired - Lifetime
- 2001-02-08 IL IL15063901A patent/IL150639A0/xx active IP Right Grant
- 2001-02-08 ES ES05106835T patent/ES2336800T3/es not_active Expired - Lifetime
- 2001-02-08 NZ NZ519973A patent/NZ519973A/en not_active IP Right Cessation
- 2001-02-08 SK SK1204-2002A patent/SK12042002A3/sk not_active Application Discontinuation
- 2001-02-08 ES ES01953630T patent/ES2263640T3/es not_active Expired - Lifetime
- 2001-02-08 CA CA002401229A patent/CA2401229C/en not_active Expired - Fee Related
- 2001-02-08 EP EP01953630A patent/EP1259489B1/en not_active Expired - Lifetime
- 2001-02-08 EP EP05106835A patent/EP1619192B1/en not_active Expired - Lifetime
- 2001-02-08 BR BR0108610-3A patent/BR0108610A/pt not_active Application Discontinuation
- 2001-02-08 AT AT05106835T patent/ATE453643T1/de not_active IP Right Cessation
- 2001-02-08 AT AT01953630T patent/ATE328872T1/de active
- 2001-02-08 GE GE4911A patent/GEP20053454B/en unknown
- 2001-02-08 AU AU28748/01A patent/AU784081B2/en not_active Ceased
- 2001-08-02 UA UA2002075792A patent/UA74813C2/uk unknown
-
2002
- 2002-07-05 BG BG106908A patent/BG65891B1/bg unknown
- 2002-07-05 IS IS6459A patent/IS2293B/is unknown
- 2002-07-08 IL IL150639A patent/IL150639A/en not_active IP Right Cessation
- 2002-08-09 CR CR6726A patent/CR6726A/es unknown
- 2002-08-13 MA MA26775A patent/MA26875A1/fr unknown
- 2002-08-21 CU CU177A patent/CU23148A3/es not_active IP Right Cessation
- 2002-08-22 ZA ZA200206768A patent/ZA200206768B/xx unknown
- 2002-08-23 NO NO20024042A patent/NO323608B1/no not_active IP Right Cessation
- 2002-08-26 HR HRP20020700 patent/HRP20020700A2/hr not_active Application Discontinuation
-
2003
- 2003-01-03 US US10/336,508 patent/US7205300B2/en not_active Expired - Fee Related
- 2003-01-03 US US10/336,532 patent/US7144882B2/en not_active Expired - Fee Related
- 2003-04-29 HK HK03103024A patent/HK1050894A1/xx not_active IP Right Cessation
-
2005
- 2005-11-18 AU AU2005234671A patent/AU2005234671B2/en not_active Ceased
-
2006
- 2006-07-21 CY CY20061101011T patent/CY1105301T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CR6726A (es) | Compuestos azapoliciclicos condensados con arilo | |
| PA8609701A1 (es) | [1,8]naftiridin-2-onas y compuestos relacionados para el tratamiento de la esquizofrenia | |
| UY27740A1 (es) | Nuevos compuestos | |
| ECSP066643A (es) | PIRIDO [2,3-d] PIRIMIDINA-2,4-DIAMINAS COMO INHIBIDORES DE PDE 2 | |
| PA8575401A1 (es) | Derivados de heteroarilamida benzocondensada de tienopiridinas utiles como agentes terapeuticos, composiciones farmaceuticas que incluyen a los mismos y metrodos para su uso | |
| PA8442001A1 (es) | Derivados de pirimidina biciclica condensada | |
| UY26782A1 (es) | Derivados del benzotiazol | |
| GT200400092A (es) | Preparacion y uso de derivados de alquilarilo para el tratamiento de la obesidad | |
| UY28510A1 (es) | Compuestos quimicos | |
| DOP2006000169A (es) | Inhibidores espiropiperidina de beta-secretasa para el tratamiento de la enfermedad de alzheimer | |
| PA8551001A1 (es) | Nuevos compuestos | |
| PA8593001A1 (es) | Derivados de pirimidina para el tratamiento del crecimiento celular anormal | |
| PA8472301A1 (es) | Derivados de isotiazol utiles como agentes anticancerosos | |
| UY28923A1 (es) | Compuestos terapéuticos: piridina como estructura base | |
| UY27714A1 (es) | 2 - heteroaril - pirimidinas inhibidoras de cdk, su preparación y su uso como medicamentos. | |
| CO5271715A1 (es) | 7-aza-indolin-2-onas sustituidas en 4 y su uso como inhibidores de proteiuna quinasa | |
| UY29781A1 (es) | Compuestos diazaspiro sustituidos, sales farmacéuticamente aceptables, composiciones farmacéuticas que contienen los compuestos o sales, métodos de preparación y usos | |
| UY26086A1 (es) | Procedimientos e intermedios para preparar compuestos anticancerosos | |
| UY29253A1 (es) | 3-amino-pirazol(3,4b)piridinas como inhibidores de proteintirosinquinasas, su preparación y uso como medicamento | |
| UY28369A1 (es) | Agentes terapéuticos | |
| HN2008001666A (es) | Derivados acidos de cicloalquilamino | |
| AR047922A1 (es) | Nuevos derivados de pentafluorsulfanilo, su obtencion y su utilizacion como agentes farmaceuticos | |
| PA8568101A1 (es) | Indolil-urea derivados de tienopiridinas utiles como agentes antiangiogenicos, y procedimientos para su uso | |
| UY28356A1 (es) | Derivados de benzimidazol, composiciones que los contienen, preparaciones de los mismos y sus usos | |
| ECSP088250A (es) | Derivados de pirazol como agentes terapéuticos |