UY28356A1 - Derivados de benzimidazol, composiciones que los contienen, preparaciones de los mismos y sus usos - Google Patents
Derivados de benzimidazol, composiciones que los contienen, preparaciones de los mismos y sus usosInfo
- Publication number
- UY28356A1 UY28356A1 UY28356A UY28356A UY28356A1 UY 28356 A1 UY28356 A1 UY 28356A1 UY 28356 A UY28356 A UY 28356A UY 28356 A UY28356 A UY 28356A UY 28356 A1 UY28356 A1 UY 28356A1
- Authority
- UY
- Uruguay
- Prior art keywords
- compositions
- benzimidazol
- preparations
- derivatives
- contain
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Se preparan compuestos de fórmula I o sales farmacéuticamente aceptables del mismo: en donde R1, R2, R3, R4 y Z son como se definen en la presente memoria descriptiva, así como sales y composiciones farmacéuticas que incluyen los compuestos. Los mismos son útiles para tratamiento, en particular en el tratamiento del dolor.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0301701A SE0301701D0 (sv) | 2003-06-10 | 2003-06-10 | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
UY28356A1 true UY28356A1 (es) | 2005-01-31 |
Family
ID=29212435
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY28356A UY28356A1 (es) | 2003-06-10 | 2004-06-10 | Derivados de benzimidazol, composiciones que los contienen, preparaciones de los mismos y sus usos |
Country Status (19)
Country | Link |
---|---|
US (2) | US7501447B2 (es) |
EP (1) | EP1636214A1 (es) |
JP (1) | JP2006527249A (es) |
KR (1) | KR20060018258A (es) |
CN (1) | CN100455580C (es) |
AR (1) | AR044666A1 (es) |
AU (1) | AU2004245298A1 (es) |
BR (1) | BRPI0411246A (es) |
CA (1) | CA2528925A1 (es) |
CO (1) | CO5660260A2 (es) |
IL (1) | IL172023A0 (es) |
IS (1) | IS8219A (es) |
NO (1) | NO20060147L (es) |
RU (1) | RU2005138366A (es) |
SE (1) | SE0301701D0 (es) |
TW (1) | TW200504029A (es) |
UY (1) | UY28356A1 (es) |
WO (1) | WO2004108712A1 (es) |
ZA (1) | ZA200509863B (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0301446D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | New Compounds |
SE0302573D0 (sv) | 2003-09-26 | 2003-09-26 | Astrazeneca Ab | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof |
SE0302570D0 (sv) * | 2003-09-26 | 2003-09-26 | Astrazeneca Ab | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof |
CN101065375A (zh) * | 2004-09-24 | 2007-10-31 | 阿斯利康(瑞典)有限公司 | 化合物、包含该化合物的组合物、其制备及其应用 |
KR101269869B1 (ko) | 2004-09-24 | 2013-06-07 | 네오메드 인스티튜트 | 벤즈이미다졸 유도체, 그를 함유하는 조성물, 그의 제조방법 및 그의 용도 |
JP2008514594A (ja) * | 2004-09-24 | 2008-05-08 | アストラゼネカ・アクチエボラーグ | ベンゾイミダゾール誘導体及びカンナビノイド受容体リガンドとしてのその使用i |
CA2581232C (en) * | 2004-09-24 | 2015-04-07 | Astrazeneca Ab | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof i |
EP1797078A4 (en) * | 2004-09-24 | 2009-04-01 | Astrazeneca Ab | BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THESE DERIVATIVES, PREPARATION AND USES THEREOF |
WO2006033628A1 (en) * | 2004-09-24 | 2006-03-30 | Astrazeneca Ab | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof |
WO2006033629A1 (en) * | 2004-09-24 | 2006-03-30 | Astrazeneca Ab | Benzimidazole derivatives and their use as cannabinoid receptor ligands |
KR100912146B1 (ko) * | 2004-10-27 | 2009-08-14 | 에프. 호프만-라 로슈 아게 | 인돌 또는 벤즈이미다졸 유도체 |
US7777040B2 (en) * | 2005-05-03 | 2010-08-17 | Cgi Pharmaceuticals, Inc. | Certain substituted ureas, as modulators of kinase activity |
UY30048A1 (es) | 2005-12-23 | 2007-07-31 | Astrazeneca Ab | Derivados sustituidos de la n,2-(1h-benzimidazol-1-il) acetamida, composiciones farmacéuticas conteniéndolos, procesos de preparación y aplicaciones |
TW200745049A (en) | 2006-03-23 | 2007-12-16 | Astrazeneca Ab | New crystalline forms |
TW200808769A (en) | 2006-04-18 | 2008-02-16 | Astrazeneca Ab | Therapeutic compounds |
TWI433839B (zh) | 2006-08-11 | 2014-04-11 | Neomed Inst | 新穎的苯并咪唑衍生物290 |
LT3572405T (lt) | 2014-09-12 | 2023-10-25 | Biohaven Therapeutics Ltd. | Benzoimidazol-1,2-ilo amidai, kaip kv7 kanalų aktyvatoriai |
CA3093976A1 (en) | 2018-03-19 | 2019-09-26 | Michael E. Bozik | Kv7 channel activators compositions and methods of use |
WO2023166450A1 (ko) * | 2022-03-04 | 2023-09-07 | 삼진제약주식회사 | 신규한 헤테로 고리 화합물 및 이를 포함하는 약학적 조성물 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE793718A (fr) | 1972-01-07 | 1973-07-05 | Merck & Co Inc | Aminobenzimidazoles |
AU722514B2 (en) | 1995-12-28 | 2000-08-03 | Fujisawa Pharmaceutical Co., Ltd. | Benzimidazole derivatives |
JP2000095767A (ja) * | 1998-09-28 | 2000-04-04 | Takeda Chem Ind Ltd | 性腺刺激ホルモン放出ホルモン拮抗剤 |
FR2789079B3 (fr) * | 1999-02-01 | 2001-03-02 | Sanofi Synthelabo | Derive d'acide pyrazolecarboxylique, sa preparation, les compositions pharmaceutiques en contenant |
SE0101387D0 (sv) * | 2001-04-20 | 2001-04-20 | Astrazeneca Ab | Novel compounds |
TWI231757B (en) | 2001-09-21 | 2005-05-01 | Solvay Pharm Bv | 1H-Imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity |
SE0203070D0 (en) * | 2002-10-16 | 2002-10-16 | Astrazeneca Ab | Novel compounds |
SE0301698D0 (sv) * | 2003-06-10 | 2003-06-10 | Astrazeneca Ab | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof |
-
2003
- 2003-06-10 SE SE0301701A patent/SE0301701D0/xx unknown
-
2004
- 2004-06-09 JP JP2006516386A patent/JP2006527249A/ja active Pending
- 2004-06-09 CN CNB2004800163234A patent/CN100455580C/zh not_active Expired - Fee Related
- 2004-06-09 KR KR1020057023713A patent/KR20060018258A/ko not_active Application Discontinuation
- 2004-06-09 AU AU2004245298A patent/AU2004245298A1/en not_active Abandoned
- 2004-06-09 RU RU2005138366/04A patent/RU2005138366A/ru not_active Application Discontinuation
- 2004-06-09 BR BRPI0411246-6A patent/BRPI0411246A/pt not_active IP Right Cessation
- 2004-06-09 CA CA002528925A patent/CA2528925A1/en not_active Abandoned
- 2004-06-09 WO PCT/GB2004/002430 patent/WO2004108712A1/en active Application Filing
- 2004-06-09 EP EP04736412A patent/EP1636214A1/en not_active Withdrawn
- 2004-06-09 US US10/557,806 patent/US7501447B2/en not_active Expired - Fee Related
- 2004-06-10 TW TW093116689A patent/TW200504029A/zh unknown
- 2004-06-10 AR ARP040102017A patent/AR044666A1/es not_active Application Discontinuation
- 2004-06-10 UY UY28356A patent/UY28356A1/es not_active Application Discontinuation
-
2005
- 2005-11-17 IL IL172023A patent/IL172023A0/en unknown
- 2005-12-05 CO CO05123380A patent/CO5660260A2/es not_active Application Discontinuation
- 2005-12-05 ZA ZA200509863A patent/ZA200509863B/en unknown
-
2006
- 2006-01-04 IS IS8219A patent/IS8219A/is unknown
- 2006-01-10 NO NO20060147A patent/NO20060147L/no not_active Application Discontinuation
-
2009
- 2009-01-08 US US12/350,322 patent/US20090111865A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1636214A1 (en) | 2006-03-22 |
JP2006527249A (ja) | 2006-11-30 |
BRPI0411246A (pt) | 2006-07-18 |
CN100455580C (zh) | 2009-01-28 |
NO20060147L (no) | 2006-03-07 |
AR044666A1 (es) | 2005-09-21 |
AU2004245298A1 (en) | 2004-12-16 |
US7501447B2 (en) | 2009-03-10 |
ZA200509863B (en) | 2006-12-27 |
WO2004108712A1 (en) | 2004-12-16 |
SE0301701D0 (sv) | 2003-06-10 |
IS8219A (is) | 2006-01-04 |
CO5660260A2 (es) | 2006-07-31 |
US20060205802A1 (en) | 2006-09-14 |
CN1805956A (zh) | 2006-07-19 |
TW200504029A (en) | 2005-02-01 |
CA2528925A1 (en) | 2004-12-16 |
IL172023A0 (en) | 2009-02-11 |
US20090111865A1 (en) | 2009-04-30 |
RU2005138366A (ru) | 2006-07-27 |
KR20060018258A (ko) | 2006-02-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
UY30316A1 (es) | Derivados sustituidos de benzamidas, nicotinamidas, propanamidas, acetamidas y carboxamidas n-(2-(piperidin-1-ilmetil)ciclohexil)sustituidas, procesos de preparacion, composiciones conteniéndolos y aplicaciones | |
UY28356A1 (es) | Derivados de benzimidazol, composiciones que los contienen, preparaciones de los mismos y sus usos | |
UY28510A1 (es) | Compuestos quimicos | |
UY31068A1 (es) | Ligandos purinoreceptores p2x, metodos para la prparacion de los mismos, composiciones farmaceuticas que los contienen y sus usos 570 | |
ECSP105253A (es) | Derivados de 5-feniltiazol y uso como inhibidores de pi3 cinasa | |
UY31334A1 (es) | 3a,4,5,6,7,7a-hexahidro-3h-benzoimidazol y derivaods de 3a, 4,5,6,,7,7a-hexahidro-3-indol, enantiómeros, diastereoisómeros, sales farmacéuticamente aceptadas, mezclas, composiciones, preparaciones y aplicaciones de las mismas | |
UY28923A1 (es) | Compuestos terapéuticos: piridina como estructura base | |
UY28536A1 (es) | Derivados de bencimidazol, composiciones que los contienen, preparacion y usos de los mismos. | |
UY29199A1 (es) | Derivados tiazol, composiciones que los contienen, procedimientos de preparación y aplicaciones | |
UY29781A1 (es) | Compuestos diazaspiro sustituidos, sales farmacéuticamente aceptables, composiciones farmacéuticas que contienen los compuestos o sales, métodos de preparación y usos | |
SV2005001979A (es) | "pirido[2,3-d]pirimidina-2,4-diaminas como inhibidores de pde 2 " ref. pc25123a | |
UY31294A1 (es) | Derivados de tetrahidrocarbozol, métodos para obtenerlos, formulaciones que los contienen y usos de los mismos | |
HN2004000232A (es) | " derivados de pirrolo(3,4-c) pirazol activos como inhibidores de quinasa, proceso para su preparacion y composiciones farmaceuticas que los comprenden." | |
UY30393A1 (es) | Derivados sustituidos de la 1-piperidin-1-il-1,3-dihidro-2h-benzimidazol-2-ona, composiciones farmacéuticas conteniéndolos, procesos de preparación y aplicaciones | |
UY31141A1 (es) | Compuestos de piperidina y sus usos | |
UY28715A1 (es) | Derivados de diarilmetil piperazina, sus preparaciones y sus usos | |
UY28357A1 (es) | Derivados de benzimidazol, composiciones que los contienen, preparación de los mismos y sus usos | |
UY30363A1 (es) | Derivados sustituidos de la n-(3-oxo-2,3-dihidro-1h-isoindol-4-il)-1-naftamida, procesos de preparacion, composiciones farmacéuticas y aplicaciones | |
CO6382176A2 (es) | Derivados de urea heterociclicos y metodos de uso de los mismos-332 | |
UY31865A (es) | Derivados de urea heterocíclicos y métodos para la utilización de los mismos | |
UY30397A1 (es) | Derivados sustituidos de la (3as, 7as)-1,3a,4,5,6,7-hexahidro-3h-benzoimidazol-2-ona, proceso de preparacion, composiciones conteniéndolos yaplicaciones | |
UY29134A1 (es) | Sulfonamidas sustituidas por derivados de bencimidazol, composiciones que la contienen, procedimiento de preparacion y aplicaciones | |
UY32316A (es) | Derivados de piperidina utiles en el tratamiento de infecciones bacterianas | |
UY28535A1 (es) | Derivados de bencimidazol, composiciones que los contienen, preparacion y usos de los mismos. | |
UY28537A1 (es) | Derivados de bencimidazol, composiciones que los contienen, preparacion y usos de los mismos. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
109 | Application deemed to be withdrawn |
Effective date: 20150602 |