DK1313740T3 - Prodrugs af imidazopyridinderivater - Google Patents

Prodrugs af imidazopyridinderivater

Info

Publication number
DK1313740T3
DK1313740T3 DK01933769T DK01933769T DK1313740T3 DK 1313740 T3 DK1313740 T3 DK 1313740T3 DK 01933769 T DK01933769 T DK 01933769T DK 01933769 T DK01933769 T DK 01933769T DK 1313740 T3 DK1313740 T3 DK 1313740T3
Authority
DK
Denmark
Prior art keywords
prodrugs
imidazopyridine derivatives
imidazopyridine
derivatives
substituents
Prior art date
Application number
DK01933769T
Other languages
English (en)
Inventor
Wolfgang-Alexander Simon
Stefan Postius
Reinhard Huber
Wolfgang Kromer
Joerg Senn-Bilfinger
Wilm Buhr
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of DK1313740T3 publication Critical patent/DK1313740T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK01933769T 2000-03-29 2001-03-28 Prodrugs af imidazopyridinderivater DK1313740T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00106695 2000-03-29

Publications (1)

Publication Number Publication Date
DK1313740T3 true DK1313740T3 (da) 2006-04-03

Family

ID=8168271

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01933769T DK1313740T3 (da) 2000-03-29 2001-03-28 Prodrugs af imidazopyridinderivater

Country Status (26)

Country Link
US (2) US20030125327A1 (da)
EP (1) EP1313740B1 (da)
JP (1) JP2003528878A (da)
KR (1) KR100860627B1 (da)
CN (1) CN1214030C (da)
AT (1) ATE311389T1 (da)
AU (1) AU783633B2 (da)
BR (1) BR0109483A (da)
CA (1) CA2404474A1 (da)
CZ (1) CZ20023194A3 (da)
DE (1) DE60115466T2 (da)
DK (1) DK1313740T3 (da)
EA (1) EA005597B1 (da)
ES (1) ES2253376T3 (da)
HK (1) HK1056175A1 (da)
HR (1) HRP20020854A2 (da)
HU (1) HUP0302331A2 (da)
IL (2) IL151200A0 (da)
MX (1) MXPA02009551A (da)
NO (1) NO20024662L (da)
NZ (1) NZ520837A (da)
PL (1) PL365116A1 (da)
SI (1) SI1313740T1 (da)
SK (1) SK286850B6 (da)
WO (1) WO2001072756A1 (da)
ZA (1) ZA200207637B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU783764B2 (en) * 2000-03-29 2005-12-01 Altana Pharma Ag Alkylated imidazopyridine derivatives
CA2426616A1 (en) 2000-10-25 2002-05-02 Altana Pharma Ag Polysubstituted imidazopyridines as gastric secretion inhibitors
CA2467652A1 (en) * 2001-11-19 2003-05-30 Altana Pharma Ag Reversible proton pump inhibitors for the treatment of airway disorders
JP2005519933A (ja) 2002-02-15 2005-07-07 アルタナ　ファルマ　アクチエンゲゼルシャフト 三環式ｎ−アシル化合物
TWI295575B (en) * 2002-04-24 2008-04-11 Altana Pharma Ag Nitrosated imidazopyridines
PL373287A1 (en) * 2002-05-07 2005-08-22 Altana Pharma Ag New combination of reversible proton pump inhibitors and airway therapeutics for treating airway disorders
CN100384842C (zh) 2002-11-19 2008-04-30 奥坦纳医药公司 8-取代的咪唑并吡啶类化合物
PL375933A1 (en) * 2002-12-20 2005-12-12 Altana Pharma Ag 8-trialkylsiloxy-2-methyl-9-phenyl-7-oxo-7,8,9,10-tetrahydroimidazo[1,2-h][1,7]naphthyridines
WO2004071391A2 (en) * 2003-02-17 2004-08-26 Altana Pharma Ag Imidazopyridines containing combinations and their use in treating gastrointestinal inflammatory disorders
AR044129A1 (es) 2003-05-06 2005-08-24 Altana Pharma Ag Compuestos intermedios de imidazopiridina. proceso de preparacion.
SA04250092B1 (ar) * 2003-05-14 2008-05-04 التانا فاروا ايه جي مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً
WO2004105795A1 (en) * 2003-05-27 2004-12-09 Altana Pharma Ag Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
CN1874772A (zh) 2003-11-03 2006-12-06 阿斯利康(瑞典)有限公司 治疗隐匿性胃食管反流的咪唑并[1,2－a]吡啶衍生物
AR046893A1 (es) * 2003-12-16 2005-12-28 Altana Pharma Ag Bencimidazoles triciclicos
WO2005058894A1 (en) 2003-12-19 2005-06-30 Altana Pharma Ag Intermediates for the preparation of tricyclic dihydropyrano -imidazo -pyridines derivatives
CA2574625A1 (en) * 2004-07-23 2006-01-26 Thijs Kuilman Process for the preparation of (2r, 3r)-2-hydroxy-3-amino-3-aryl-propionamide and (2r, 3r)-2-hydroxy-3-amino-3-aryl-propionic acid alkyl ester
CA2582256A1 (en) * 2004-10-01 2006-04-13 Altana Pharma Ag Substituted tricyclic benzimidazoles
JP5802898B2 (ja) 2009-07-09 2015-11-04 ラクオリア創薬株式会社 消化管運動異常が関与する疾患を治療するためのアシッドポンプ拮抗剤

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
US4673679A (en) * 1986-05-14 1987-06-16 E. I. Du Pont De Nemours And Company Use of prodrugs of 3-hydroxymorphinans to prevent bitter taste upon buccal, nasal or sublingual administration
WO1992021341A1 (en) * 1991-05-31 1992-12-10 Pfizer Inc. Use of rapamycin prodrugs as immunosuppressant agents
DE4308095A1 (de) * 1993-03-13 1994-09-15 Hoechst Ag Prodrug-Derivate von Arzneimittelwirkstoffen mit Hydroxylgruppen, Verfahren zu deren Herstellung und ihre Verwendung
SE9401197D0 (sv) * 1994-04-11 1994-04-11 Astra Ab Active compounds
US6073004A (en) 1996-12-17 2000-06-06 Ericsson Inc. Emergency call initiator
EA002402B1 (ru) * 1997-03-24 2002-04-25 Бык Гульден Ломберг Хемише Фабрик Гмбх Тетрагидропиридо-соединения
CA2289542A1 (en) * 1997-05-28 1998-12-03 Byk Gulden Lomberg Chemische Fabrik Gmbh Fused dihydropyrans
HUP0001555A3 (en) * 1997-10-30 2001-01-29 Altana Pharma Ag Tetrahydro-imidazo-naphthyridine derivatives, pharmaceutical compositions thereof and process for their preparation
PL193616B1 (pl) * 1998-09-23 2007-02-28 Altana Pharma Ag Tetrahydropirydoetery
EP1127059B1 (en) * 1998-11-03 2008-02-20 Nycomed GmbH Imidazonaphthyridines
AU783764B2 (en) 2000-03-29 2005-12-01 Altana Pharma Ag Alkylated imidazopyridine derivatives

Also Published As

Publication number Publication date
IL151200A0 (en) 2003-04-10
HK1056175A1 (en) 2004-02-06
CN1426414A (zh) 2003-06-25
HRP20020854A2 (en) 2004-12-31
ES2253376T3 (es) 2006-06-01
CZ20023194A3 (cs) 2003-01-15
BR0109483A (pt) 2003-06-10
IL151200A (en) 2009-11-18
JP2003528878A (ja) 2003-09-30
NO20024662D0 (no) 2002-09-27
CN1214030C (zh) 2005-08-10
ATE311389T1 (de) 2005-12-15
EA005597B1 (ru) 2005-04-28
CA2404474A1 (en) 2001-10-04
NZ520837A (en) 2005-01-28
KR20020084262A (ko) 2002-11-04
PL365116A1 (en) 2004-12-27
DE60115466D1 (de) 2006-01-05
EP1313740B1 (en) 2005-11-30
NO20024662L (no) 2002-09-27
MXPA02009551A (es) 2004-05-14
HUP0302331A2 (hu) 2003-12-29
US20030125327A1 (en) 2003-07-03
DE60115466T2 (de) 2006-07-20
AU6016601A (en) 2001-10-08
EP1313740A1 (en) 2003-05-28
SK286850B6 (sk) 2009-06-05
US7189736B2 (en) 2007-03-13
KR100860627B1 (ko) 2008-09-29
SI1313740T1 (sl) 2006-04-30
US20040198764A1 (en) 2004-10-07
SK13852002A3 (sk) 2003-02-04
EA200200875A1 (ru) 2003-04-24
ZA200207637B (en) 2004-04-08
WO2001072756A1 (en) 2001-10-04
AU783633B2 (en) 2005-11-17

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