BR0109483A - Pró-drogas de derivados de imidazopiridina - Google Patents

Pró-drogas de derivados de imidazopiridina

Info

Publication number
BR0109483A
BR0109483A BR0109483-1A BR0109483A BR0109483A BR 0109483 A BR0109483 A BR 0109483A BR 0109483 A BR0109483 A BR 0109483A BR 0109483 A BR0109483 A BR 0109483A
Authority
BR
Brazil
Prior art keywords
imidazopyridine derivative
derivative prodrugs
prodrugs
imidazopyridine
substituents
Prior art date
Application number
BR0109483-1A
Other languages
English (en)
Inventor
Wolfgang-Alexander Simon
Stefan Postius
Reinhard Huber
Wolfgang Kromer
Joerg Senn-Bilfinger
Wilm Buhr
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of BR0109483A publication Critical patent/BR0109483A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Abstract

"PRó-DROGAS DE DERIVADOS DE IMIDAZOPIRIDINA". Os compostos de fórmula (1), em que os substituintes têm os significados mencionados na descrição, são adequados para a prevenção e o tratamento de doenças gastrointestinais.
BR0109483-1A 2000-03-29 2001-03-28 Pró-drogas de derivados de imidazopiridina BR0109483A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00106695 2000-03-29
PCT/EP2001/003514 WO2001072756A1 (en) 2000-03-29 2001-03-28 Prodrugs of imidazopyridine derivatives

Publications (1)

Publication Number Publication Date
BR0109483A true BR0109483A (pt) 2003-06-10

Family

ID=8168271

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0109483-1A BR0109483A (pt) 2000-03-29 2001-03-28 Pró-drogas de derivados de imidazopiridina

Country Status (26)

Country Link
US (2) US20030125327A1 (pt)
EP (1) EP1313740B1 (pt)
JP (1) JP2003528878A (pt)
KR (1) KR100860627B1 (pt)
CN (1) CN1214030C (pt)
AT (1) ATE311389T1 (pt)
AU (1) AU783633B2 (pt)
BR (1) BR0109483A (pt)
CA (1) CA2404474A1 (pt)
CZ (1) CZ20023194A3 (pt)
DE (1) DE60115466T2 (pt)
DK (1) DK1313740T3 (pt)
EA (1) EA005597B1 (pt)
ES (1) ES2253376T3 (pt)
HK (1) HK1056175A1 (pt)
HR (1) HRP20020854A2 (pt)
HU (1) HUP0302331A2 (pt)
IL (2) IL151200A0 (pt)
MX (1) MXPA02009551A (pt)
NO (1) NO20024662L (pt)
NZ (1) NZ520837A (pt)
PL (1) PL365116A1 (pt)
SI (1) SI1313740T1 (pt)
SK (1) SK286850B6 (pt)
WO (1) WO2001072756A1 (pt)
ZA (1) ZA200207637B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA02009552A (es) * 2000-03-29 2004-05-14 Altana Pharma Ag Derivados de imidazopiridina alquilada.
EA008151B1 (ru) 2000-10-25 2007-04-27 Алтана Фарма Аг Полизамещенные имидазопиридины в качестве ингибиторов желудочной секреции
AU2002342917A1 (en) * 2001-11-19 2003-06-10 Altana Pharma Ag Reversible proton pump inhibitors for the treatment of airway disorders
NZ535227A (en) 2002-02-15 2006-03-31 Altana Pharma Ag Tricyclic n-acyl compounds
TWI295575B (en) * 2002-04-24 2008-04-11 Altana Pharma Ag Nitrosated imidazopyridines
CN1652822A (zh) * 2002-05-07 2005-08-10 奥坦纳医药公司 用于治疗气道病症的可逆质子泵抑制剂和气道治疗剂的新组合
BR0316201A (pt) 2002-11-19 2005-10-04 Altana Pharma Ag Imidazopiridinas 8-substituìdas
EA010107B1 (ru) * 2002-12-20 2008-06-30 Алтана Фарма Аг Силиловые простые эфиры
MXPA05008490A (es) * 2003-02-17 2005-10-18 Altana Pharma Ag Combinaciones que contienen imidazopiridinas y su uso en el tratamiento de enfermedades gastrointestinales inflamatorias.
AR044129A1 (es) 2003-05-06 2005-08-24 Altana Pharma Ag Compuestos intermedios de imidazopiridina. proceso de preparacion.
SA04250092B1 (ar) * 2003-05-14 2008-05-04 التانا فاروا ايه جي مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً
CA2526566A1 (en) * 2003-05-27 2004-12-09 Altana Pharma Ag Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
US20080280944A1 (en) 2003-11-03 2008-11-13 Paula Fernstrom Imidazo[1,2-A]Pyridine Derivatives For The Treatment Of Silent Gastro-Esophageal Reflux
AR046893A1 (es) * 2003-12-16 2005-12-28 Altana Pharma Ag Bencimidazoles triciclicos
EP1697358A1 (en) 2003-12-19 2006-09-06 Altana Pharma AG Intermediates for the preparation of tricyclic dihydropyrano -imidazo -pyridines derivatives
JP2008507487A (ja) * 2004-07-23 2008-03-13 ディーエスエム アイピー アセッツ ビー．ブイ． （２ｒ，３ｒ）−２−ヒドロキシ−３−アミノ−３−アリール−プロピオンアミドおよび（２ｒ，３ｒ）−２−ヒドロキシ−３−アミノ−３−アリール−プロピオン酸アルキルエステルの調製方法
AU2005291284A1 (en) * 2004-10-01 2006-04-13 Altana Pharma Ag Substituted tricyclic benzimidazoles
CN102470126A (zh) 2009-07-09 2012-05-23 拉夸里亚创药株式会社 用于治疗与异常肠胃运动有关的疾病的酸泵拮抗剂

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
US4673679A (en) 1986-05-14 1987-06-16 E. I. Du Pont De Nemours And Company Use of prodrugs of 3-hydroxymorphinans to prevent bitter taste upon buccal, nasal or sublingual administration
WO1992021341A1 (en) 1991-05-31 1992-12-10 Pfizer Inc. Use of rapamycin prodrugs as immunosuppressant agents
DE4308095A1 (de) * 1993-03-13 1994-09-15 Hoechst Ag Prodrug-Derivate von Arzneimittelwirkstoffen mit Hydroxylgruppen, Verfahren zu deren Herstellung und ihre Verwendung
SE9401197D0 (sv) * 1994-04-11 1994-04-11 Astra Ab Active compounds
US6073004A (en) 1996-12-17 2000-06-06 Ericsson Inc. Emergency call initiator
IL131407A0 (en) 1997-03-24 2001-01-28 Byk Gulden Lomberg Chem Fab Tetrahydropyrido compounds medicaments containing the same and the use thereof
EP0984969B1 (en) * 1997-05-28 2008-07-09 Nycomed GmbH Fused dihydropyrans
HUP0001555A3 (en) * 1997-10-30 2001-01-29 Altana Pharma Ag Tetrahydro-imidazo-naphthyridine derivatives, pharmaceutical compositions thereof and process for their preparation
SI1115725T1 (en) 1998-09-23 2003-06-30 Altana Pharma Ag Tetrahydropyridoethers
EP1127059B1 (en) * 1998-11-03 2008-02-20 Nycomed GmbH Imidazonaphthyridines
MXPA02009552A (es) * 2000-03-29 2004-05-14 Altana Pharma Ag Derivados de imidazopiridina alquilada.

Also Published As

Publication number Publication date
SI1313740T1 (sl) 2006-04-30
AU6016601A (en) 2001-10-08
ZA200207637B (en) 2004-04-08
MXPA02009551A (es) 2004-05-14
NO20024662D0 (no) 2002-09-27
CZ20023194A3 (cs) 2003-01-15
SK13852002A3 (sk) 2003-02-04
NO20024662L (no) 2002-09-27
JP2003528878A (ja) 2003-09-30
ATE311389T1 (de) 2005-12-15
CN1426414A (zh) 2003-06-25
IL151200A0 (en) 2003-04-10
SK286850B6 (sk) 2009-06-05
PL365116A1 (en) 2004-12-27
NZ520837A (en) 2005-01-28
DK1313740T3 (da) 2006-04-03
DE60115466D1 (de) 2006-01-05
IL151200A (en) 2009-11-18
HUP0302331A2 (hu) 2003-12-29
US20040198764A1 (en) 2004-10-07
EA200200875A1 (ru) 2003-04-24
US7189736B2 (en) 2007-03-13
EA005597B1 (ru) 2005-04-28
KR100860627B1 (ko) 2008-09-29
ES2253376T3 (es) 2006-06-01
EP1313740A1 (en) 2003-05-28
AU783633B2 (en) 2005-11-17
CN1214030C (zh) 2005-08-10
DE60115466T2 (de) 2006-07-20
WO2001072756A1 (en) 2001-10-04
EP1313740B1 (en) 2005-11-30
HRP20020854A2 (en) 2004-12-31
US20030125327A1 (en) 2003-07-03
CA2404474A1 (en) 2001-10-04
KR20020084262A (ko) 2002-11-04
HK1056175A1 (en) 2004-02-06

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

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