ATE297904T1 - Halo-alkoxycarbonylverbindungen - Google Patents

Halo-alkoxycarbonylverbindungen

Info

Publication number
ATE297904T1
ATE297904T1 AT98913417T AT98913417T ATE297904T1 AT E297904 T1 ATE297904 T1 AT E297904T1 AT 98913417 T AT98913417 T AT 98913417T AT 98913417 T AT98913417 T AT 98913417T AT E297904 T1 ATE297904 T1 AT E297904T1
Authority
AT
Austria
Prior art keywords
halo
alkoxycarbonyl compounds
alkoxycarbonyl
compounds
prodrugs
Prior art date
Application number
AT98913417T
Other languages
English (en)
Inventor
Brent Blackburn
Alan G Olivero
Kirk Robarge
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE297904T1 publication Critical patent/ATE297904T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT98913417T 1997-04-15 1998-04-08 Halo-alkoxycarbonylverbindungen ATE297904T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84336997A 1997-04-15 1997-04-15
PCT/US1998/007092 WO1998046576A2 (en) 1997-04-15 1998-04-08 Halo-alkoxycarbonyl prodrugs

Publications (1)

Publication Number Publication Date
ATE297904T1 true ATE297904T1 (de) 2005-07-15

Family

ID=25289769

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98913417T ATE297904T1 (de) 1997-04-15 1998-04-08 Halo-alkoxycarbonylverbindungen

Country Status (6)

Country Link
EP (1) EP0975608B1 (de)
JP (1) JP2001521522A (de)
AT (1) ATE297904T1 (de)
AU (1) AU6797298A (de)
DE (1) DE69830577T2 (de)
WO (1) WO1998046576A2 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458772B1 (en) 1909-10-07 2002-10-01 Medivir Ab Prodrugs
AU5826100A (en) 1999-07-13 2001-01-30 F. Hoffmann-La Roche Ag Benzazepinones and quinazolines
EP1206446B1 (de) 1999-08-07 2004-05-26 Boehringer Ingelheim Pharma GmbH & Co.KG Carbonsäureamide, deren herstellung und deren verwendung als arzneimittel
MXPA03007349A (es) 2001-02-24 2003-12-04 Boehringer Ingelheim Pharma Derivados de xantina, su preparacion y su empleo como medicamentos.
DK1532149T3 (da) 2002-08-21 2010-05-10 Boehringer Ingelheim Pharma 8-[3-amino-piperiden-1-yl]-xanthiner, fremstilling deraf og anvendelse deraf som lægemiddel
DE10254304A1 (de) 2002-11-21 2004-06-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
AU2004240940A1 (en) 2003-05-20 2004-12-02 Genentech, Inc. Thiocarbamate inhibitors of alpha-4 integrins
CA2561210A1 (en) 2004-04-10 2005-10-20 Boehringer Ingelheim International Gmbh Novel 2-amino-imidazo[4,5-d]pyridazin-4-ones and 2-amino-imidazo[4,5-c]pyridin-4-ones, production and use thereof as medicaments
CA2565237C (en) 2004-04-30 2012-12-11 Genentech, Inc. Quinoxaline inhibitors of hedgehog signalling
DE102004030502A1 (de) 2004-06-24 2006-01-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Imidazole und Triazole, deren Herstellung und Verwendung als Arzneimittel
DE102004044221A1 (de) 2004-09-14 2006-03-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue 3-Methyl-7-butinyl-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
US20090281089A1 (en) 2008-04-11 2009-11-12 Genentech, Inc. Pyridyl inhibitors of hedgehog signalling
WO2011072064A1 (en) 2009-12-08 2011-06-16 Array Biopharma Inc. S piro [chroman - 4, 4 ' - imidazol] ones as beta - secretase inhibitors
WO2011123674A1 (en) 2010-03-31 2011-10-06 Array Biopharma Inc. Compounds for treating neurodegenerative diseases
WO2011130741A1 (en) 2010-04-16 2011-10-20 Array Biopharma Inc. Compounds for treating neurodegenerative diseases
NO2755614T3 (de) 2012-01-03 2018-03-31
AU2017319500C1 (en) 2016-08-31 2022-10-20 Les Laboratoires Servier Inhibitors of cellular metabolic processes
WO2022115521A1 (en) 2020-11-25 2022-06-02 Servier Pharmaceuticals, Llc (heteo)aryl substituted pyrrolo-, pyrazolo- and triazolopyridazine derivates as mat2a inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250679A (en) * 1991-10-18 1993-10-05 Genentech, Inc. Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor

Also Published As

Publication number Publication date
JP2001521522A (ja) 2001-11-06
EP0975608A2 (de) 2000-02-02
WO1998046576A2 (en) 1998-10-22
DE69830577D1 (de) 2005-07-21
EP0975608B1 (de) 2005-06-15
AU6797298A (en) 1998-11-11
DE69830577T2 (de) 2006-05-04
WO1998046576A3 (en) 1999-01-28

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