CS227012B2 - Method of preparing 2-amino-3-benzoyl-phenylacetamide - Google Patents
Method of preparing 2-amino-3-benzoyl-phenylacetamide Download PDFInfo
- Publication number
- CS227012B2 CS227012B2 CS806196A CS619680A CS227012B2 CS 227012 B2 CS227012 B2 CS 227012B2 CS 806196 A CS806196 A CS 806196A CS 619680 A CS619680 A CS 619680A CS 227012 B2 CS227012 B2 CS 227012B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- amino
- solution
- mol
- added
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7886079A | 1979-09-26 | 1979-09-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS227012B2 true CS227012B2 (en) | 1984-04-16 |
Family
ID=22146633
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS806196A CS227012B2 (en) | 1979-09-26 | 1980-09-11 | Method of preparing 2-amino-3-benzoyl-phenylacetamide |
Country Status (36)
| Country | Link |
|---|---|
| JP (1) | JPS5657751A (hu) |
| KR (1) | KR840000763B1 (hu) |
| AT (1) | AT374170B (hu) |
| AU (1) | AU532359B2 (hu) |
| BE (1) | BE885393A (hu) |
| BR (1) | BR8006042A (hu) |
| CA (1) | CA1128512A (hu) |
| CH (1) | CH646138A5 (hu) |
| CS (1) | CS227012B2 (hu) |
| DE (1) | DE3035688A1 (hu) |
| DK (1) | DK154136C (hu) |
| EG (1) | EG15020A (hu) |
| ES (2) | ES495329A0 (hu) |
| FI (1) | FI72967C (hu) |
| FR (1) | FR2465710A1 (hu) |
| GB (1) | GB2059963B (hu) |
| GR (1) | GR70049B (hu) |
| HK (1) | HK59383A (hu) |
| HU (1) | HU183215B (hu) |
| IE (1) | IE50268B1 (hu) |
| IL (1) | IL60999A (hu) |
| IN (3) | IN151313B (hu) |
| IT (1) | IT1133823B (hu) |
| KE (1) | KE3307A (hu) |
| LU (1) | LU82797A1 (hu) |
| MX (1) | MX7159E (hu) |
| NL (1) | NL8005346A (hu) |
| NO (1) | NO152128C (hu) |
| NZ (1) | NZ195061A (hu) |
| PH (1) | PH22628A (hu) |
| PL (1) | PL128998B1 (hu) |
| PT (1) | PT71839B (hu) |
| SE (1) | SE448626B (hu) |
| SG (1) | SG42983G (hu) |
| YU (3) | YU41734B (hu) |
| ZA (1) | ZA805476B (hu) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL61945A (en) * | 1980-02-19 | 1984-09-30 | Robins Co Inc A H | 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them |
| US6646001B2 (en) | 1997-12-19 | 2003-11-11 | Alcon Manufacturing, Ltd. | Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension |
| US6066671A (en) * | 1997-12-19 | 2000-05-23 | Alcon Laboratories, Inc. | Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides |
| GB9727523D0 (en) | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
| AR030345A1 (es) * | 2000-08-14 | 2003-08-20 | Alcon Inc | Metodo de tratamiento de desordenes relacionados con angiogenesis |
| SI1423168T1 (sl) | 2001-09-03 | 2006-06-30 | Newron Pharm Spa | Farmacevtski sestavek, ki vsebuje gabapentin ali njegov analog in alfa-aminoamid, in njegova analgetska uporaba |
| EP1438956A1 (en) | 2003-01-16 | 2004-07-21 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful as antimigraine agents |
| CZ301776B6 (cs) * | 2009-06-08 | 2010-06-16 | Farmak, A.S. | Postup prípravy 2-amino-3-benzoylfenylacetamidu (nepafenacu) s minimem vedlejších produktu |
| CN112794809B (zh) * | 2019-11-14 | 2023-12-29 | 南京济群医药科技股份有限公司 | 一种高纯度奈帕芬胺中间体的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1226344A (hu) * | 1967-07-31 | 1971-03-24 | ||
| CH577461A5 (hu) * | 1975-08-13 | 1976-07-15 | Robins Co Inc A H | |
| IL61945A (en) * | 1980-02-19 | 1984-09-30 | Robins Co Inc A H | 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them |
-
1980
- 1980-09-04 ZA ZA00805476A patent/ZA805476B/xx unknown
- 1980-09-08 IL IL60999A patent/IL60999A/xx unknown
- 1980-09-08 AU AU62116/80A patent/AU532359B2/en not_active Ceased
- 1980-09-11 CS CS806196A patent/CS227012B2/cs unknown
- 1980-09-17 IE IE1946/80A patent/IE50268B1/en unknown
- 1980-09-20 EG EG80573A patent/EG15020A/xx active
- 1980-09-22 BR BR8006042A patent/BR8006042A/pt unknown
- 1980-09-22 GR GR62936A patent/GR70049B/el unknown
- 1980-09-22 DE DE19803035688 patent/DE3035688A1/de active Granted
- 1980-09-23 AT AT0474580A patent/AT374170B/de not_active IP Right Cessation
- 1980-09-23 PH PH24613A patent/PH22628A/en unknown
- 1980-09-24 SE SE8006668A patent/SE448626B/sv not_active IP Right Cessation
- 1980-09-24 LU LU82797A patent/LU82797A1/fr unknown
- 1980-09-24 FI FI803002A patent/FI72967C/fi not_active IP Right Cessation
- 1980-09-25 NL NL8005346A patent/NL8005346A/nl not_active Application Discontinuation
- 1980-09-25 CH CH719180A patent/CH646138A5/fr not_active IP Right Cessation
- 1980-09-25 DK DK405780A patent/DK154136C/da not_active IP Right Cessation
- 1980-09-25 HU HU802347A patent/HU183215B/hu not_active IP Right Cessation
- 1980-09-25 KR KR1019800003740A patent/KR840000763B1/ko active
- 1980-09-25 ES ES495329A patent/ES495329A0/es active Granted
- 1980-09-25 FR FR8020596A patent/FR2465710A1/fr active Granted
- 1980-09-25 PL PL1980226919A patent/PL128998B1/pl unknown
- 1980-09-25 NO NO802834A patent/NO152128C/no unknown
- 1980-09-25 BE BE0/202226A patent/BE885393A/fr not_active IP Right Cessation
- 1980-09-25 CA CA361,068A patent/CA1128512A/en not_active Expired
- 1980-09-25 GB GB8030955A patent/GB2059963B/en not_active Expired
- 1980-09-25 PT PT71839A patent/PT71839B/pt unknown
- 1980-09-25 MX MX809050U patent/MX7159E/es unknown
- 1980-09-25 YU YU2450/80A patent/YU41734B/xx unknown
- 1980-09-26 IT IT24948/80A patent/IT1133823B/it active
- 1980-09-26 IN IN1092/CAL/80A patent/IN151313B/en unknown
- 1980-09-26 NZ NZ195061A patent/NZ195061A/en unknown
- 1980-09-26 JP JP13415280A patent/JPS5657751A/ja active Granted
-
1981
- 1981-06-12 ES ES503019A patent/ES8204715A1/es not_active Expired
-
1982
- 1982-12-30 IN IN1508/CAL/82A patent/IN156254B/en unknown
- 1982-12-30 IN IN1509/CAL/82A patent/IN156255B/en unknown
-
1983
- 1983-03-28 YU YU730/83A patent/YU43305B/xx unknown
- 1983-03-28 YU YU731/83A patent/YU43306B/xx unknown
- 1983-07-19 SG SG42983A patent/SG42983G/en unknown
- 1983-07-21 KE KE3307A patent/KE3307A/xx unknown
- 1983-11-24 HK HK593/83A patent/HK59383A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5674685B2 (ja) | Ｄｈｏｄｈ阻害剤としての、ヒドロキシル基および／またはカルボキシル基含有アミンとアミノニコチン酸誘導体との付加塩 | |
| US4313949A (en) | Method of producing an inhibitory effect on blood platelet aggregation | |
| JPS62161728A (ja) | 抗菌剤 | |
| EP0004532B1 (de) | 1-Aryloxy-3-nitratoalkylamino-2-propanole, Verfahren zu ihrer Herstellung und ihre pharmazeutischen Zubereitungen | |
| PL154186B1 (en) | Method for manufacturing arylic derivatives of the hydroxamic acid | |
| RU2195452C2 (ru) | Цианогуанидины, способы их получения и фармацевтический препарат на их основе | |
| WO2022122987A1 (en) | Anthelmintic compounds comprising a pyridine structure | |
| CA3164098A1 (en) | Anthelmintic compounds comprising a quinoline structure | |
| CS227012B2 (en) | Method of preparing 2-amino-3-benzoyl-phenylacetamide | |
| KR860001578B1 (ko) | 3-티오메틸 파리딘 유도체의 제조방법 | |
| EA002037B1 (ru) | Цианогуанидины в качестве ингибиторов пролиферации клеток | |
| JPH0153266B2 (hu) | ||
| CZ9904240A3 (cs) | Kyanoguanidiny jako inhibitory buněčné proliferace | |
| HU199440B (en) | Process for producing morpholine derivatives and pharmaceutical compositions comprising the compounds | |
| CZ20011417A3 (cs) | Sklovitá forma 8-(3-(N-((E)-3-(6-acetamidopyridin-3-yl)-akryloylglycyl)-N-methylamino)-2,6-dichlorbenzyloxy)-2-methylchinolinu | |
| WO2012130850A1 (de) | Gewebetargeting mit onkoziden verbrückten diphenylderivaten zur selektiven behandlung von sexualorgantumoren | |
| PL208284B1 (pl) | Pochodne benzo[g]chinoliny, kompozycje je zawierające oraz zastosowanie takich pochodnych | |
| CZ321095A3 (en) | Heterocyclic compounds | |
| DK160761B (da) | Pyrimidin-thioalkylpyridin-derivater og laegemiddel indeholdende disse forbindelser | |
| CZ20012482A3 (cs) | Deriváty ((aminoiminomethyl)amino)alkankarboxamidu a jejich pouľití v terapii | |
| EP3867243B1 (en) | Novel n-(isopropyl-triazolyl)pyridinyl)-heteroaryl-carboxamide derivatives and use thereof | |
| US4100287A (en) | Pyrimidine derivative | |
| JP2004137185A (ja) | チオフェン骨格を有する抗菌剤 | |
| US8946286B2 (en) | Organic amine salts of aminobenzoic acid derivatives and method for producing same | |
| JPH01113398A (ja) | 光学活性なジヒドロピリジン−５−ホスホン酸エステル |