CS207612B2 - Method of making the trans-5-aryl-2,3,4a,5,9b-hexa-hydro-1h-pyrido 4,3-b indoles - Google Patents

Method of making the trans-5-aryl-2,3,4a,5,9b-hexa-hydro-1h-pyrido 4,3-b indoles Download PDF

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Publication number
CS207612B2
CS207612B2 CS783239A CS323978A CS207612B2 CS 207612 B2 CS207612 B2 CS 207612B2 CS 783239 A CS783239 A CS 783239A CS 323978 A CS323978 A CS 323978A CS 207612 B2 CS207612 B2 CS 207612B2
Authority
CS
Czechoslovakia
Prior art keywords
acid
fluorophenyl
trans
pyrido
compounds
Prior art date
Application number
CS783239A
Other languages
Czech (cs)
English (en)
Inventor
Willard Mck Welch
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to CS796221A priority Critical patent/CS207613B2/cs
Priority to CS796223A priority patent/CS207615B2/cs
Priority to CS796222A priority patent/CS207614B2/cs
Publication of CS207612B2 publication Critical patent/CS207612B2/cs

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS783239A 1977-05-23 1978-05-18 Method of making the trans-5-aryl-2,3,4a,5,9b-hexa-hydro-1h-pyrido 4,3-b indoles CS207612B2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CS796221A CS207613B2 (cs) 1977-05-23 1979-09-14 Způsob výroby trans-5-aryl-2,3,4,4a,5,9b-hexahydro-lH-pyrido[4,3-b]- indolů
CS796223A CS207615B2 (cs) 1977-05-23 1979-09-14 Způsob výroby 4a,9b-trans-hexahydro;-karbolinových derivátů
CS796222A CS207614B2 (cs) 1977-05-23 1979-09-14 Způsob výroby 4a, 9b-trans-hexahydro-/*-karbolinových derivátů

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79939277A 1977-05-23 1977-05-23

Publications (1)

Publication Number Publication Date
CS207612B2 true CS207612B2 (en) 1981-08-31

Family

ID=25175793

Family Applications (1)

Application Number Title Priority Date Filing Date
CS783239A CS207612B2 (en) 1977-05-23 1978-05-18 Method of making the trans-5-aryl-2,3,4a,5,9b-hexa-hydro-1h-pyrido 4,3-b indoles

Country Status (31)

Country Link
JP (1) JPS53144600A (it)
AR (2) AR217688A1 (it)
AT (1) AT368995B (it)
AU (1) AU499618B1 (it)
BE (1) BE867249A (it)
CA (1) CA1094071A (it)
CH (1) CH634321A5 (it)
CS (1) CS207612B2 (it)
DD (4) DD145536A5 (it)
DE (1) DE2822465C2 (it)
DK (1) DK226678A (it)
EG (1) EG13590A (it)
FI (1) FI63402C (it)
FR (1) FR2392023A1 (it)
GB (1) GB1586655A (it)
GR (1) GR69985B (it)
HU (3) HU187782B (it)
IE (1) IE46975B1 (it)
IL (1) IL54755A (it)
IT (1) IT1096307B (it)
LU (1) LU79684A1 (it)
NL (1) NL7804210A (it)
NO (2) NO150204C (it)
NZ (1) NZ187333A (it)
PH (1) PH13756A (it)
PL (5) PL117107B1 (it)
PT (1) PT68058B (it)
SE (2) SE441448B (it)
SU (4) SU873883A3 (it)
YU (4) YU91478A (it)
ZA (1) ZA782918B (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
US4451655A (en) * 1982-05-17 1984-05-29 Pfizer Inc. Process for preparing carboline derivatives and compounds used in their preparation
RU2106864C1 (ru) * 1995-10-23 1998-03-20 Николай Серафимович Зефиров Средство для лечения болезни альцгеймера
SE9604786D0 (sv) * 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
US6974825B1 (en) 1996-12-20 2005-12-13 Astrazeneca Canada Inc. Compounds with analgesic effect
SE9904675D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0101773D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101769D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101771D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101770D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
DE20204239U1 (de) 2002-03-16 2002-05-29 Funke Kunststoffe GmbH, 48324 Sendenhorst Universal-Rohrdichtung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205452A1 (es) * 1973-12-06 1976-05-07 Endo Lab Metodo para preparar nuevos trans-2, 3, 4, 4a, 5, 9b-hexahidro-5-fenil-1h-pirido(4,3-b) indoles
JPS50126699A (it) * 1974-03-20 1975-10-04
US4001263A (en) * 1974-04-01 1977-01-04 Pfizer Inc. 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines

Also Published As

Publication number Publication date
JPS53144600A (en) 1978-12-15
YU221882A (en) 1983-01-21
NO151862C (no) 1985-06-19
NO151862B (no) 1985-03-11
DD145536A5 (de) 1980-12-17
BE867249A (fr) 1978-11-20
AT368995B (de) 1982-11-25
HU185009B (en) 1984-11-28
SE441448B (sv) 1985-10-07
DD145537A5 (de) 1980-12-17
CH634321A5 (en) 1983-01-31
SU873883A3 (ru) 1981-10-15
NO781770L (no) 1978-11-24
DE2822465C2 (de) 1986-08-28
IL54755A0 (en) 1978-07-31
PL114541B1 (en) 1981-02-28
SU843749A3 (ru) 1981-06-30
NO150204B (no) 1984-05-28
PH13756A (en) 1980-09-17
DE2822465A1 (de) 1978-11-30
NO150204C (no) 1984-09-05
PT68058B (en) 1979-10-24
DK226678A (da) 1978-11-24
YU91478A (en) 1983-01-21
AR221721A1 (es) 1981-03-13
PL117107B1 (en) 1981-07-31
PT68058A (en) 1978-06-01
SE8305917L (sv) 1983-10-27
GR69985B (it) 1982-07-22
NO831790L (no) 1978-11-24
FI63402C (fi) 1983-06-10
SE448459B (sv) 1987-02-23
IT1096307B (it) 1985-08-26
PL116944B1 (en) 1981-07-31
HU188802B (en) 1986-05-28
JPS5711912B2 (it) 1982-03-08
SU818484A3 (ru) 1981-03-30
PL206903A1 (pl) 1979-10-22
SE7803625L (sv) 1978-11-24
NL7804210A (nl) 1978-11-27
IE46975B1 (en) 1983-11-16
AU499618B1 (en) 1979-04-26
ATA369678A (de) 1982-04-15
DD138321A5 (de) 1979-10-24
FI63402B (fi) 1983-02-28
YU40796B (en) 1986-06-30
CA1094071A (en) 1981-01-20
NZ187333A (en) 1984-05-31
PL114547B1 (en) 1981-02-28
IE781013L (en) 1978-11-23
YU221782A (en) 1983-01-21
FI781612A (fi) 1978-11-24
FR2392023B1 (it) 1980-11-07
AR217688A1 (es) 1980-04-15
EG13590A (en) 1982-03-31
SE8305917D0 (sv) 1983-10-27
SU841589A3 (ru) 1981-06-23
GB1586655A (en) 1981-03-25
FR2392023A1 (fr) 1978-12-22
ZA782918B (en) 1979-06-27
DD146186A5 (de) 1981-01-28
LU79684A1 (fr) 1979-12-06
YU221682A (en) 1983-01-21
IT7823673A0 (it) 1978-05-22
HU187782B (en) 1986-02-28
IL54755A (en) 1981-02-27

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