CS205046B2 - Method of producing new 2-phenyl-3-aroylbenzothiophenone derivatives - Google Patents

Method of producing new 2-phenyl-3-aroylbenzothiophenone derivatives Download PDF

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Publication number
CS205046B2
CS205046B2 CS766974A CS697476A CS205046B2 CS 205046 B2 CS205046 B2 CS 205046B2 CS 766974 A CS766974 A CS 766974A CS 697476 A CS697476 A CS 697476A CS 205046 B2 CS205046 B2 CS 205046B2
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Czechoslovakia
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group
compound
mixture
hydrogen
added
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CS766974A
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Czech (cs)
English (en)
Inventor
Charles D Jones
Tulio Suarez
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Lilly Co Eli
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Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CS205046B2 publication Critical patent/CS205046B2/cs

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/64—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CS766974A 1975-10-28 1976-10-28 Method of producing new 2-phenyl-3-aroylbenzothiophenone derivatives CS205046B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62601075A 1975-10-28 1975-10-28

Publications (1)

Publication Number Publication Date
CS205046B2 true CS205046B2 (en) 1981-04-30

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CS766974A CS205046B2 (en) 1975-10-28 1976-10-28 Method of producing new 2-phenyl-3-aroylbenzothiophenone derivatives
CS766974A CS205047B2 (en) 1975-10-28 1976-10-28 Method of producing novel 2-phenyl-3-aroylbenzothiophenone derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS766974A CS205047B2 (en) 1975-10-28 1976-10-28 Method of producing novel 2-phenyl-3-aroylbenzothiophenone derivatives

Country Status (31)

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US (1) US4133814A (es)
JP (1) JPS5253851A (es)
AR (3) AR222959A1 (es)
AT (1) AT357520B (es)
AU (1) AU505360B2 (es)
BE (1) BE847719A (es)
BG (2) BG27553A3 (es)
CA (1) CA1090795A (es)
CH (3) CH635336A5 (es)
CS (2) CS205046B2 (es)
DD (1) DD127461A5 (es)
DE (1) DE2647907C2 (es)
DK (1) DK152045C (es)
ES (2) ES452695A1 (es)
FR (1) FR2329271A1 (es)
GB (1) GB1570610A (es)
GR (1) GR61776B (es)
HU (1) HU179012B (es)
IE (1) IE44392B1 (es)
IL (1) IL50773A (es)
MX (1) MX4584E (es)
NL (1) NL7611975A (es)
NZ (1) NZ182429A (es)
PH (1) PH14219A (es)
PL (2) PL114190B1 (es)
PT (1) PT65755B (es)
RO (1) RO70769A (es)
SE (1) SE426945B (es)
SU (2) SU701539A3 (es)
YU (1) YU262076A (es)
ZA (1) ZA766440B (es)

Families Citing this family (301)

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FR2329271A1 (fr) 1977-05-27
CH634316A5 (de) 1983-01-31
IL50773A0 (en) 1976-12-31
MX4584E (es) 1982-06-25
BE847719A (fr) 1977-04-28
YU262076A (en) 1983-01-21
PL193308A1 (pl) 1978-03-28
DK484876A (da) 1977-04-29
ES452694A1 (es) 1977-11-16
ATA800876A (de) 1979-12-15
CA1090795A (en) 1980-12-02
BG28065A4 (en) 1980-02-25
AR215930A1 (es) 1979-11-15
AR222796A1 (es) 1981-06-30
AR222959A1 (es) 1981-07-15

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