BG28065A4 - Method of obtaining of 2-phenyl-3-aroylbenzothiophenes - Google Patents

Method of obtaining of 2-phenyl-3-aroylbenzothiophenes

Info

Publication number
BG28065A4
BG28065A4 BG7636899A BG3689976A BG28065A4 BG 28065 A4 BG28065 A4 BG 28065A4 BG 7636899 A BG7636899 A BG 7636899A BG 3689976 A BG3689976 A BG 3689976A BG 28065 A4 BG28065 A4 BG 28065A4
Authority
BG
Bulgaria
Prior art keywords
aroylbenzothiophenes
phenyl
obtaining
Prior art date
Application number
BG7636899A
Other languages
Bulgarian (bg)
English (en)
Inventor
Jones
Suarez
Original Assignee
Eli Lilly And Co,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Co,Us filed Critical Eli Lilly And Co,Us
Publication of BG28065A4 publication Critical patent/BG28065A4/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/64—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BG7636899A 1975-10-28 1976-10-28 Method of obtaining of 2-phenyl-3-aroylbenzothiophenes BG28065A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62601075A 1975-10-28 1975-10-28

Publications (1)

Publication Number Publication Date
BG28065A4 true BG28065A4 (en) 1980-02-25

Family

ID=24508581

Family Applications (2)

Application Number Title Priority Date Filing Date
BG7636899A BG28065A4 (en) 1975-10-28 1976-10-28 Method of obtaining of 2-phenyl-3-aroylbenzothiophenes
BG7634550A BG27553A3 (en) 1975-10-28 1976-10-28 Method of obtaining of 2- phenyl- 3- aroylxenzothiophenes

Family Applications After (1)

Application Number Title Priority Date Filing Date
BG7634550A BG27553A3 (en) 1975-10-28 1976-10-28 Method of obtaining of 2- phenyl- 3- aroylxenzothiophenes

Country Status (31)

Country Link
US (1) US4133814A (xx)
JP (1) JPS5253851A (xx)
AR (3) AR222959A1 (xx)
AT (1) AT357520B (xx)
AU (1) AU505360B2 (xx)
BE (1) BE847719A (xx)
BG (2) BG28065A4 (xx)
CA (1) CA1090795A (xx)
CH (3) CH635336A5 (xx)
CS (2) CS205047B2 (xx)
DD (1) DD127461A5 (xx)
DE (1) DE2647907C2 (xx)
DK (1) DK152045C (xx)
ES (2) ES452694A1 (xx)
FR (1) FR2329271A1 (xx)
GB (1) GB1570610A (xx)
GR (1) GR61776B (xx)
HU (1) HU179012B (xx)
IE (1) IE44392B1 (xx)
IL (1) IL50773A (xx)
MX (1) MX4584E (xx)
NL (1) NL7611975A (xx)
NZ (1) NZ182429A (xx)
PH (1) PH14219A (xx)
PL (2) PL107979B1 (xx)
PT (1) PT65755B (xx)
RO (1) RO70769A (xx)
SE (1) SE426945B (xx)
SU (2) SU701539A3 (xx)
YU (1) YU262076A (xx)
ZA (1) ZA766440B (xx)

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UA32427C2 (uk) * 1993-10-15 2000-12-15 Елі Ліллі Енд Компані Застосування бензотіофенів або їх фармацевтично прийнятних солей або сольватів для інгібування ангіогенезу і/або ангіогенних захворювань
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US5457113A (en) * 1993-10-15 1995-10-10 Eli Lilly And Company Methods for inhibiting vascular smooth muscle cell proliferation and restinosis
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SE426945B (sv) 1983-02-21
GB1570610A (en) 1980-07-02
AR222959A1 (es) 1981-07-15
CS205046B2 (en) 1981-04-30
AR215930A1 (es) 1979-11-15
JPS61343B2 (xx) 1986-01-08
YU262076A (en) 1983-01-21
BE847719A (fr) 1977-04-28
PT65755B (en) 1978-04-27
SU701539A3 (ru) 1979-11-30
DK152045B (da) 1988-01-25
BG27553A3 (en) 1979-11-12
FR2329271A1 (fr) 1977-05-27
CH634316A5 (de) 1983-01-31
PL114190B1 (en) 1981-01-31
CA1090795A (en) 1980-12-02
JPS5253851A (en) 1977-04-30
IL50773A0 (en) 1976-12-31
CH635582A5 (de) 1983-04-15
DE2647907C2 (de) 1985-01-24
PH14219A (en) 1981-04-02
CH635336A5 (de) 1983-03-31
NL7611975A (nl) 1977-05-02
AU505360B2 (en) 1979-11-15

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