CS202600B2 - Process for preparing new derivatives of 5,11-dihydro-6h-pyrido/2,3-b//1,4/benzodiazepin-6-one - Google Patents

Process for preparing new derivatives of 5,11-dihydro-6h-pyrido/2,3-b//1,4/benzodiazepin-6-one Download PDF

Info

Publication number
CS202600B2
CS202600B2 CS783472A CS347278A CS202600B2 CS 202600 B2 CS202600 B2 CS 202600B2 CS 783472 A CS783472 A CS 783472A CS 347278 A CS347278 A CS 347278A CS 202600 B2 CS202600 B2 CS 202600B2
Authority
CS
Czechoslovakia
Prior art keywords
methyl
methylamino
ethyl
amino
pyrido
Prior art date
Application number
CS783472A
Other languages
Czech (cs)
English (en)
Inventor
Guenther Schmidt
Matyas Leitold
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2724478A external-priority patent/DE2724478C2/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of CS202600B2 publication Critical patent/CS202600B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
CS783472A 1977-05-31 1978-05-29 Process for preparing new derivatives of 5,11-dihydro-6h-pyrido/2,3-b//1,4/benzodiazepin-6-one CS202600B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2724478A DE2724478C2 (de) 1977-05-31 1977-05-31 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
CS202600B2 true CS202600B2 (en) 1981-01-30

Family

ID=6010286

Family Applications (1)

Application Number Title Priority Date Filing Date
CS783472A CS202600B2 (en) 1977-05-31 1978-05-29 Process for preparing new derivatives of 5,11-dihydro-6h-pyrido/2,3-b//1,4/benzodiazepin-6-one

Country Status (30)

Country Link
US (1) US4210648A (xx)
JP (1) JPS543092A (xx)
AT (1) AT361929B (xx)
AU (1) AU516712B2 (xx)
BE (1) BE867639A (xx)
BG (1) BG28712A3 (xx)
CA (1) CA1081220A (xx)
CH (1) CH637956A5 (xx)
CS (1) CS202600B2 (xx)
DD (1) DD135490A5 (xx)
DK (1) DK148233C (xx)
ES (1) ES470269A1 (xx)
FI (1) FI63233C (xx)
FR (1) FR2392991A1 (xx)
GB (1) GB1581500A (xx)
GR (1) GR64535B (xx)
HK (1) HK19381A (xx)
HU (1) HU180540B (xx)
IE (1) IE46909B1 (xx)
IL (1) IL54815A (xx)
MY (1) MY8100362A (xx)
NL (1) NL7805848A (xx)
NO (1) NO149065C (xx)
NZ (1) NZ187428A (xx)
PL (1) PL113999B1 (xx)
PT (1) PT68114A (xx)
SE (1) SE437831B (xx)
SU (1) SU797578A3 (xx)
YU (1) YU129478A (xx)
ZA (1) ZA783086B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2053187A (en) * 1979-07-09 1981-02-04 Grissmann Chem Ltd Process for preparing pyrenzepine
GR72993B (xx) * 1980-01-24 1984-01-25 Crc Ricerca Chim
IT1130973B (it) * 1980-03-17 1986-06-18 Microsules Argentina Sa De S C Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one,derivati finali ed intermedi di sintesi in tal modo ottenuti
DE3212794A1 (de) * 1982-04-06 1983-10-13 Basf Ag, 6700 Ludwigshafen 5,6-dihydro-11-alkylen-morphantridin-6-one, ihre herstellung und diese enthaltende arzneimittel
IT1212742B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Derivati dibenzo [1,4]diazepinonici pirido [1,4] benzodiazepinonici,pirido [1,5] benzodiazepinonici e loro attivita' farmacologica
IT1212743B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Sali quaternari di derivati di benzo[ 1,4 ]diazepinonici,pirido [1,4]benzodiazepinonici,prido [1,5]benzodiazepinonici e loro atti vita' farmacologica
DE3626095A1 (de) * 1986-07-31 1988-02-11 Thomae Gmbh Dr K Neue substituierte pyrido(2,3-b)(1,4)benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3643666A1 (de) * 1986-12-20 1988-06-30 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3802334A1 (de) * 1988-01-27 1989-08-10 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820346A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820347A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Verwendung von in 11-stellung substituierten 5,11-dihydro-6h-pyrido(2,3-b) (1,4)benzodiazepin-6-onen zur behandlung von bradycardien und bradyarrhythmien in der human- und veterinaermedizin
US5264432A (en) * 1989-07-31 1993-11-23 Arzneimittelwerk Dresden G.M.B.H 5-(1-aminoacyl)-5,10-dihydro-11H-dibenzo[b,e](1,4)diazepin-11-ones
DE3930262A1 (de) * 1989-09-11 1991-03-21 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3930266A1 (de) * 1989-09-11 1991-03-14 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5418229A (en) * 1990-01-06 1995-05-23 Alker; David Muscarinic receptor antagonists
GB9000302D0 (en) * 1990-01-06 1990-03-07 Pfizer Ltd Muscarinic receptor antagonists
AU2005263578B2 (en) 2004-07-16 2010-09-02 Proteosys Ag Muscarinic antagonists with PARP and SIR modulating activity as agents for inflammatory diseases
WO2010081823A1 (en) 2009-01-13 2010-07-22 Proteosys Ag Pirenzepine as otoprotective agent

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795183B1 (de) * 1968-08-20 1972-07-20 Thomae Gmbh Dr K 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel
US3691152A (en) * 1971-03-10 1972-09-12 Texaco Inc Hydrodesulfurization and blending of residue-containing petroleum oil

Also Published As

Publication number Publication date
HK19381A (en) 1981-05-15
FI781690A (fi) 1978-12-01
ZA783086B (en) 1980-02-27
DD135490A5 (de) 1979-05-09
HU180540B (en) 1983-03-28
JPS543092A (en) 1979-01-11
GR64535B (en) 1980-04-10
NO149065B (no) 1983-10-31
PL207192A1 (pl) 1979-04-23
NZ187428A (en) 1981-01-23
BG28712A3 (en) 1980-06-16
BE867639A (fr) 1978-11-30
SE437831B (sv) 1985-03-18
DK148233C (da) 1985-10-21
NL7805848A (nl) 1978-12-04
SE7806287L (sv) 1978-12-01
JPS6216952B2 (xx) 1987-04-15
US4210648A (en) 1980-07-01
IL54815A (en) 1981-07-31
FI63233B (fi) 1983-01-31
FR2392991B1 (xx) 1982-10-22
FR2392991A1 (fr) 1978-12-29
PL113999B1 (en) 1981-01-31
ES470269A1 (es) 1979-01-01
NO149065C (no) 1984-02-08
PT68114A (de) 1978-06-01
NO781880L (no) 1978-12-01
DK239378A (da) 1978-12-01
ATA367778A (de) 1980-09-15
AU3662478A (en) 1979-12-06
IE781073L (en) 1978-11-30
AT361929B (de) 1981-04-10
CH637956A5 (de) 1983-08-31
DK148233B (da) 1985-05-13
FI63233C (fi) 1983-05-10
GB1581500A (en) 1980-12-17
IE46909B1 (en) 1983-11-02
CA1081220A (en) 1980-07-08
MY8100362A (en) 1981-12-31
YU129478A (en) 1983-02-28
SU797578A3 (ru) 1981-01-15
AU516712B2 (en) 1981-06-18

Similar Documents

Publication Publication Date Title
CS202600B2 (en) Process for preparing new derivatives of 5,11-dihydro-6h-pyrido/2,3-b//1,4/benzodiazepin-6-one
WO2022031678A1 (en) Kras g12d inhibitors
AU702324B2 (en) Cyclic GMP-specific phosphodiesterase inhibitors
KR102604942B1 (ko) 증식성 장애의 치료에 사용하기 위한 트리사이클릭 화합물
KR20040087335A (ko) 질소 함유 복소환 화합물
JP7111704B2 (ja) 二環式ヘテロアリール誘導体
ES2345207T3 (es) Compuestos pirazolo-heteroarilicos utiles para tratar enfermedades mediadas por tnf-alfa e il-1.
JP2017516855A (ja) 特定のタンパク質キナーゼ阻害剤
NZ511015A (en) 1, 6-Dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one derivatives useful for treating impotence
EP0125607A2 (en) Pyrido(1,5)benzodiazepinone derivatives and pharmacological activities thereof
EP2697222A1 (en) Tri- and tetracyclic pyrazolo[3,4-b]pyridine compounds as antineoplastic agent
DK171023B1 (da) Basisk substituerede tricykliske diazepinoner, fremgangsmåde til deres fremstilling og lægemiddel indeholdende sådanne forbindelser
JP2011518127A (ja) ヒスタミンｈ３受容体アンタゴニストとしてのテトラヒドロナフチリジンおよびそれらのアザ誘導体
US7361662B2 (en) Pyridopyrimidinone compounds, method for production thereof and medicaments comprising the same
TW201815792A (zh) 橋聯哌啶衍生物
KR20040087333A (ko) 헤테로아릴 치환된 2-피리디닐 및2-피리미디닐-6,7,8,9-테트라히드로피리미도[1,2-ａ]피리미딘-4-온 유도체
EP0383465B1 (en) Tricyclic fused pyrimidine derivatives, their production and use
US20210040102A1 (en) Imidazo-fused heterocycles and uses thereof
US6800623B2 (en) Method of treating schizophrenia
CS207619B2 (en) Method of making the new derivatives of 5,11-dihydro-6h-pyrido 2,3-b 1,4 benzodiazepin-6-on
KR20010102544A (ko) 카르바모일 테트라히드로피리딘 유도체
JP7335242B2 (ja) ピリミジン誘導体
JP4385620B2 (ja) 含窒素複素環化合物
DK170670B1 (da) Kondenserede diazepinoner, fremgangsmåde til deresfremstilling, lægemidler indeholdende en sådan diazepinon, samt anvendelse af sådanne diazepinoner til fremstilling af lægemidler
CZ111192A3 (en) Condensed diazepinones, process of their preparation and pharmaceutical compositions in which they are comprised