FR2392991A1 - Nouvelles 5,11-dihydro-6h-pyrido(2,3-b) (1,4) benzodiazepin-6-ones substituees en position 11, procedes pour leur preparation et medicaments renfermant ces composes - Google Patents

Nouvelles 5,11-dihydro-6h-pyrido(2,3-b) (1,4) benzodiazepin-6-ones substituees en position 11, procedes pour leur preparation et medicaments renfermant ces composes

Info

Publication number
FR2392991A1
FR2392991A1 FR7816248A FR7816248A FR2392991A1 FR 2392991 A1 FR2392991 A1 FR 2392991A1 FR 7816248 A FR7816248 A FR 7816248A FR 7816248 A FR7816248 A FR 7816248A FR 2392991 A1 FR2392991 A1 FR 2392991A1
Authority
FR
France
Prior art keywords
dihydro
new
benzodiazepin
pyrido
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7816248A
Other languages
English (en)
Other versions
FR2392991B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2724478A external-priority patent/DE2724478C2/de
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of FR2392991A1 publication Critical patent/FR2392991A1/fr
Application granted granted Critical
Publication of FR2392991B1 publication Critical patent/FR2392991B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention a pour objet de nouvelles 5,11-dihydro-6HpyridoØ2,3-bõØ1,4õbenzodiazépin-6-ones de formule :
FR7816248A 1977-05-31 1978-05-31 Nouvelles 5,11-dihydro-6h-pyrido(2,3-b) (1,4) benzodiazepin-6-ones substituees en position 11, procedes pour leur preparation et medicaments renfermant ces composes Granted FR2392991A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2724478A DE2724478C2 (de) 1977-05-31 1977-05-31 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
FR2392991A1 true FR2392991A1 (fr) 1978-12-29
FR2392991B1 FR2392991B1 (fr) 1982-10-22

Family

ID=6010286

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7816248A Granted FR2392991A1 (fr) 1977-05-31 1978-05-31 Nouvelles 5,11-dihydro-6h-pyrido(2,3-b) (1,4) benzodiazepin-6-ones substituees en position 11, procedes pour leur preparation et medicaments renfermant ces composes

Country Status (30)

Country Link
US (1) US4210648A (fr)
JP (1) JPS543092A (fr)
AT (1) AT361929B (fr)
AU (1) AU516712B2 (fr)
BE (1) BE867639A (fr)
BG (1) BG28712A3 (fr)
CA (1) CA1081220A (fr)
CH (1) CH637956A5 (fr)
CS (1) CS202600B2 (fr)
DD (1) DD135490A5 (fr)
DK (1) DK148233C (fr)
ES (1) ES470269A1 (fr)
FI (1) FI63233C (fr)
FR (1) FR2392991A1 (fr)
GB (1) GB1581500A (fr)
GR (1) GR64535B (fr)
HK (1) HK19381A (fr)
HU (1) HU180540B (fr)
IE (1) IE46909B1 (fr)
IL (1) IL54815A (fr)
MY (1) MY8100362A (fr)
NL (1) NL7805848A (fr)
NO (1) NO149065C (fr)
NZ (1) NZ187428A (fr)
PL (1) PL113999B1 (fr)
PT (1) PT68114A (fr)
SE (1) SE437831B (fr)
SU (1) SU797578A3 (fr)
YU (1) YU129478A (fr)
ZA (1) ZA783086B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2474501A1 (fr) * 1980-01-24 1981-07-31 Poli Ind Chimica Spa 11-(2'-imidazol-1''-yl)-acetyl-5,11-dihydro-6h-pyrido (2,3-b) (1,4) benzodiazepin-6-ones, leur procede de preparation et leur application dans la therapie de l'ulcere
EP0326066A2 (fr) * 1988-01-27 1989-08-02 Dr. Karl Thomae GmbH Diazépinones condensées, procédé pour leur préparation et médicament les contenant

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2053187A (en) * 1979-07-09 1981-02-04 Grissmann Chem Ltd Process for preparing pyrenzepine
IT1130973B (it) * 1980-03-17 1986-06-18 Microsules Argentina Sa De S C Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one,derivati finali ed intermedi di sintesi in tal modo ottenuti
DE3212794A1 (de) * 1982-04-06 1983-10-13 Basf Ag, 6700 Ludwigshafen 5,6-dihydro-11-alkylen-morphantridin-6-one, ihre herstellung und diese enthaltende arzneimittel
IT1212742B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Derivati dibenzo [1,4]diazepinonici pirido [1,4] benzodiazepinonici,pirido [1,5] benzodiazepinonici e loro attivita' farmacologica
IT1212743B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Sali quaternari di derivati di benzo[ 1,4 ]diazepinonici,pirido [1,4]benzodiazepinonici,prido [1,5]benzodiazepinonici e loro atti vita' farmacologica
DE3626095A1 (de) * 1986-07-31 1988-02-11 Thomae Gmbh Dr K Neue substituierte pyrido(2,3-b)(1,4)benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3643666A1 (de) * 1986-12-20 1988-06-30 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820346A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820347A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Verwendung von in 11-stellung substituierten 5,11-dihydro-6h-pyrido(2,3-b) (1,4)benzodiazepin-6-onen zur behandlung von bradycardien und bradyarrhythmien in der human- und veterinaermedizin
US5264432A (en) * 1989-07-31 1993-11-23 Arzneimittelwerk Dresden G.M.B.H 5-(1-aminoacyl)-5,10-dihydro-11H-dibenzo[b,e](1,4)diazepin-11-ones
DE3930266A1 (de) * 1989-09-11 1991-03-14 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3930262A1 (de) * 1989-09-11 1991-03-21 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5418229A (en) * 1990-01-06 1995-05-23 Alker; David Muscarinic receptor antagonists
GB9000302D0 (en) * 1990-01-06 1990-03-07 Pfizer Ltd Muscarinic receptor antagonists
KR20070033032A (ko) 2004-07-16 2007-03-23 프로테오시스 악티엔게젤샤프트 세포보호제로서 ｐａｒｐ 및 ｓｉｒ 조절 활성을 갖는무스카린 길항제
EP2387405A2 (fr) 2009-01-13 2011-11-23 ProteoSys AG Pirenzépine en tant qu'agent utilisé dans le traitement du cancer

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2016009A1 (fr) * 1968-08-20 1970-04-30 Thomae Gmbh Dr K

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3691152A (en) * 1971-03-10 1972-09-12 Texaco Inc Hydrodesulfurization and blending of residue-containing petroleum oil

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2016009A1 (fr) * 1968-08-20 1970-04-30 Thomae Gmbh Dr K

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2474501A1 (fr) * 1980-01-24 1981-07-31 Poli Ind Chimica Spa 11-(2'-imidazol-1''-yl)-acetyl-5,11-dihydro-6h-pyrido (2,3-b) (1,4) benzodiazepin-6-ones, leur procede de preparation et leur application dans la therapie de l'ulcere
EP0326066A2 (fr) * 1988-01-27 1989-08-02 Dr. Karl Thomae GmbH Diazépinones condensées, procédé pour leur préparation et médicament les contenant
EP0326066A3 (fr) * 1988-01-27 1991-01-30 Dr. Karl Thomae GmbH Diazépinones condensées, procédé pour leur préparation et médicament les contenant

Also Published As

Publication number Publication date
FI63233C (fi) 1983-05-10
IE781073L (en) 1978-11-30
HK19381A (en) 1981-05-15
NO149065C (no) 1984-02-08
US4210648A (en) 1980-07-01
PL113999B1 (en) 1981-01-31
NL7805848A (nl) 1978-12-04
GR64535B (en) 1980-04-10
CA1081220A (fr) 1980-07-08
IE46909B1 (en) 1983-11-02
NZ187428A (en) 1981-01-23
ATA367778A (de) 1980-09-15
MY8100362A (en) 1981-12-31
DK239378A (da) 1978-12-01
NO149065B (no) 1983-10-31
SU797578A3 (ru) 1981-01-15
JPS543092A (en) 1979-01-11
DK148233C (da) 1985-10-21
DD135490A5 (de) 1979-05-09
FI781690A (fi) 1978-12-01
GB1581500A (en) 1980-12-17
CS202600B2 (en) 1981-01-30
NO781880L (no) 1978-12-01
CH637956A5 (de) 1983-08-31
FI63233B (fi) 1983-01-31
SE437831B (sv) 1985-03-18
ES470269A1 (es) 1979-01-01
YU129478A (en) 1983-02-28
AU3662478A (en) 1979-12-06
AU516712B2 (en) 1981-06-18
FR2392991B1 (fr) 1982-10-22
SE7806287L (sv) 1978-12-01
BE867639A (fr) 1978-11-30
BG28712A3 (en) 1980-06-16
JPS6216952B2 (fr) 1987-04-15
PL207192A1 (pl) 1979-04-23
IL54815A (en) 1981-07-31
PT68114A (de) 1978-06-01
HU180540B (en) 1983-03-28
ZA783086B (en) 1980-02-27
AT361929B (de) 1981-04-10
DK148233B (da) 1985-05-13

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