FR2383187A1 - Derives du cepheme, leur procede de preparation et leur application en therapeutique - Google Patents

Derives du cepheme, leur procede de preparation et leur application en therapeutique

Info

Publication number
FR2383187A1
FR2383187A1 FR7807174A FR7807174A FR2383187A1 FR 2383187 A1 FR2383187 A1 FR 2383187A1 FR 7807174 A FR7807174 A FR 7807174A FR 7807174 A FR7807174 A FR 7807174A FR 2383187 A1 FR2383187 A1 FR 2383187A1
Authority
FR
France
Prior art keywords
derivatives
cepheme
therapeutics
preparation
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR7807174A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of FR2383187A1 publication Critical patent/FR2383187A1/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

L'invention a pour objet des derivés du céphème de formule:
FR7807174A 1977-03-12 1978-03-13 Derives du cepheme, leur procede de preparation et leur application en therapeutique Pending FR2383187A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772710902 DE2710902A1 (de) 1977-03-12 1977-03-12 Cephemderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
FR2383187A1 true FR2383187A1 (fr) 1978-10-06

Family

ID=6003494

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7807174A Pending FR2383187A1 (fr) 1977-03-12 1978-03-13 Derives du cepheme, leur procede de preparation et leur application en therapeutique

Country Status (17)

Country Link
US (1) US4201779A (fr)
JP (1) JPS53112895A (fr)
AT (1) AT363182B (fr)
AU (1) AU519253B2 (fr)
BE (1) BE864828A (fr)
DE (1) DE2710902A1 (fr)
DK (1) DK107978A (fr)
ES (1) ES467601A1 (fr)
FI (1) FI780757A (fr)
FR (1) FR2383187A1 (fr)
GB (1) GB1601328A (fr)
HU (1) HU176534B (fr)
IL (1) IL54248A0 (fr)
IT (1) IT1095393B (fr)
NL (1) NL7802671A (fr)
SE (1) SE7802853L (fr)
ZA (1) ZA781433B (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2511377A1 (fr) * 1980-09-25 1983-02-18 Toyama Chemical Co Ltd Nouvelles cephalosporines, et leurs sels
FR2528839A1 (fr) * 1982-06-17 1983-12-23 Toyama Chemical Co Ltd Nouveau procede de production de derives de l'acide 2-(2-aminothiazol-4-yl) glyoxylique ou d'un de ses sels, les intermediaires necessaires a la synthese de ces derniers, et le procede de production desdits intermediaires
FR2533216A1 (fr) * 1982-09-22 1984-03-23 Toyama Chemical Co Ltd Nouvelles cephalosporines, et leurs sels
EP0439097A2 (fr) * 1990-01-22 1991-07-31 Biochemie Gesellschaft M.B.H. Dérivés de céphalosporine

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4440766A (en) * 1976-03-09 1984-04-03 Fujisawa Pharmaceutical Co., Ltd. 3,7-Disubstituted-3-cephem-4-carboxylic acid compounds
US4370326A (en) * 1977-09-13 1983-01-25 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and composition
FR2387235A1 (fr) * 1978-01-23 1978-11-10 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne
DE2822861A1 (de) * 1978-05-26 1979-11-29 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
JPS54160392A (en) * 1978-06-02 1979-12-19 Takeda Chem Ind Ltd Cephalosporin derivative and its preparation
MA18686A1 (fr) * 1978-07-07 1980-10-01 Ciba Geigy Ag Composes aminothiazoliques
US4409215A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. 7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof
ZA806977B (en) * 1979-11-19 1981-10-28 Fujisawa Pharmaceutical Co 7-acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
US5243043A (en) * 1980-02-18 1993-09-07 Roussel Uclaf Cephalosporins
US4404376A (en) 1980-04-30 1983-09-13 American Cyanamid Company Cephalosporanic acid derivatives
US4336375A (en) 1980-04-30 1982-06-22 American Cyanamid Company Cephalosporanic acid derivatives
US4404374A (en) 1980-04-30 1983-09-13 American Cyanamid Company Cephalosporanic acid derivatives
US4404375A (en) 1980-04-30 1983-09-13 American Cyanamid Company Cephalosporanic acid derivatives
JPS5877886A (ja) * 1981-11-02 1983-05-11 Toyama Chem Co Ltd 新規セフアロスポリン類
US4443374A (en) * 1982-02-01 1984-04-17 E. R. Squibb & Sons, Inc. Process for preparing (3S)-3-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]-acetyl]amino]-2-oxo-1-azetidinesulfonic acid, and 4-substituted derivatives
AT382149B (de) * 1984-04-10 1987-01-12 Biochemie Gmbh Verfahren zur herstellung von syn-isomeren von thioessigsaeureestern
AT381944B (de) * 1984-04-10 1986-12-10 Biochemie Gmbh Verfahren zur herstellung von cephalosporinantibiotika
FR2722790B1 (fr) 1994-07-19 1996-10-04 Roussel Uclaf Nouvelles cephalosporines comportant en position 7 un radical benzyloxymino subtitue, leur procede de preparation leur application comme medicaments
US20040242863A1 (en) * 2003-05-27 2004-12-02 Carenini Alessandro Riccardo Preparation of cefalosporins intermediates and conversion of said intermediates into active compound precursors
KR101448553B1 (ko) 2005-12-07 2014-10-13 바실리어 파마슈티카 아게 베타-락타마아제 저해제 및 모노박탐 항생물질의 유용한 조합

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5119765A (en) * 1974-08-09 1976-02-17 Takeda Chemical Industries Ltd Aminochiazoorujudotaino seizoho
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
JPS5919114B2 (ja) * 1975-08-25 1984-05-02 武田薬品工業株式会社 セフアロスポリンの製造法

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2511377A1 (fr) * 1980-09-25 1983-02-18 Toyama Chemical Co Ltd Nouvelles cephalosporines, et leurs sels
FR2528839A1 (fr) * 1982-06-17 1983-12-23 Toyama Chemical Co Ltd Nouveau procede de production de derives de l'acide 2-(2-aminothiazol-4-yl) glyoxylique ou d'un de ses sels, les intermediaires necessaires a la synthese de ces derniers, et le procede de production desdits intermediaires
FR2533216A1 (fr) * 1982-09-22 1984-03-23 Toyama Chemical Co Ltd Nouvelles cephalosporines, et leurs sels
EP0439097A2 (fr) * 1990-01-22 1991-07-31 Biochemie Gesellschaft M.B.H. Dérivés de céphalosporine
EP0439097A3 (en) * 1990-01-22 1992-07-15 Biochemie Gesellschaft M.B.H. Cephalosporin derivative

Also Published As

Publication number Publication date
DK107978A (da) 1978-09-13
HU176534B (en) 1981-03-28
ZA781433B (en) 1979-02-28
IT1095393B (it) 1985-08-10
AU519253B2 (en) 1981-11-19
IL54248A0 (en) 1978-06-15
JPS53112895A (en) 1978-10-02
IT7821102A0 (it) 1978-03-10
ES467601A1 (es) 1979-06-16
ATA174178A (de) 1980-12-15
NL7802671A (nl) 1978-09-14
SE7802853L (sv) 1978-09-13
AU3406478A (en) 1979-09-13
AT363182B (de) 1981-07-10
BE864828A (fr) 1978-09-13
GB1601328A (en) 1981-10-28
US4201779A (en) 1980-05-06
DE2710902A1 (de) 1978-09-21
FI780757A (fi) 1978-09-13

Similar Documents

Publication Publication Date Title
FR2383187A1 (fr) Derives du cepheme, leur procede de preparation et leur application en therapeutique
FR2435248A1 (fr) Derives de 4-anilinoquinazoline, leur procede de preparation et leur application en therapeutique
FR2383157A1 (fr) Derives de chalcone, leur procede de preparation et leur application en therapeutique
LU79335A1 (fr) Procede de preparation de derives d'acetamides utiles notamment en therapeutique
FR2381028A1 (fr) Derives d'acide benzoique, leur procede de preparation et leur application en therapeutique
FR2405246A1 (fr) Nouveaux derives de pyrrole, leur procede de preparation et leurs applications en therapeutique
FR2400500A1 (fr) Derives d'acides cycloalcoylidenemethylphenylacetiques, leur procede de preparation et leur application en therapeutique
FR2453151A1 (fr) Derives de la vitamine d3, leur procede de preparation et leur application en therapeutique
FR2431494A1 (fr) Nouveaux derives du benzofuranne, leur procede de preparation et leur application en therapeutique
FR2378016A1 (fr) 1-alkylthiophenyl-2,3,4,5-tetrahydro-1h-3-benzazepine substituees et leur application en therapeutique
FR2385720A1 (fr) Thieno(2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application en therapeutique
FR2392959A1 (fr) Amino-acides et procede d'obtention
FR2383944A1 (fr) Derives de bis-benzimidazolyle substitues, leur procede de preparation et leur application en therapeutique
FR2383943A1 (fr) Triazinones, leur procede de preparation et leur application en therapeutique
FR2355831A1 (fr) Derives de benzazocine, leur procede de preparation et leur application therapeutique
FR2421178A1 (fr) Conjugue d'un derive d'acyl-n-acetylmuramyl-peptide et d'un antigene, son procede de preparation et son application therapeutique
FR2390445A1 (fr) Nouveaux derives du chromene, leur procede de preparation et leurs applications en therapeutique
FR2406635A1 (fr) Nouveaux derives du benzo(d)thiazole, leur procede de preparation et leurs applications en therapeutique
FR2381788A1 (fr) 1-thio-beta-d-glucopyrannosides de (phosphine trisubstituee)-or (i) et leur application en therapeutique
FR2453163A1 (fr) Derives de benzothiazole, leur procede de preparation et leurs applications en therapeutique
FR2375219A1 (fr) Derives de l'imidazole, leur procede de preparation et leur application
FR2405936A1 (fr) Derives du pyrrole, leur procede de preparation et leurs applications, notamment en therapeutique
FR2378017A1 (fr) Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines, leur procede de preparation et application en therapeutique
FR2370050A1 (fr) Derives quinolizidylideniques de xanthenes, thioxanthenes et dibenzoxepines, leur procede de preparation et leur application en therapeutique
FR2399406A1 (fr) Derives de perhydronaphtalenepentol et leur utilisation therapeutique