DK239378A - 5,11-dihydro-6h-pyrido(2,3-b)(1,4)-benzodiazepin-6-oner, der er substitueret i 11-stillingen og femgangsmaade til deres fremstilling - Google Patents

5,11-dihydro-6h-pyrido(2,3-b)(1,4)-benzodiazepin-6-oner, der er substitueret i 11-stillingen og femgangsmaade til deres fremstilling

Info

Publication number
DK239378A
DK239378A DK239378A DK239378A DK239378A DK 239378 A DK239378 A DK 239378A DK 239378 A DK239378 A DK 239378A DK 239378 A DK239378 A DK 239378A DK 239378 A DK239378 A DK 239378A
Authority
DK
Denmark
Prior art keywords
benzodiazepin
pyrido
dihydro
procedures
preparation
Prior art date
Application number
DK239378A
Other languages
English (en)
Other versions
DK148233B (da
DK148233C (da
Inventor
G Schmidt
M Leitold
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2724478A external-priority patent/DE2724478C2/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DK239378A publication Critical patent/DK239378A/da
Publication of DK148233B publication Critical patent/DK148233B/da
Application granted granted Critical
Publication of DK148233C publication Critical patent/DK148233C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK239378A 1977-05-31 1978-05-30 Analogifremgangsmaade til fremstilling af 5,11-dihydro-6h-pyrido-(2,3-b)(1,4)benzodiazepin-6-oner, der er substitueret i 11-stillingen, eller salte deraf DK148233C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2724478 1977-05-31
DE2724478A DE2724478C2 (de) 1977-05-31 1977-05-31 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (3)

Publication Number Publication Date
DK239378A true DK239378A (da) 1978-12-01
DK148233B DK148233B (da) 1985-05-13
DK148233C DK148233C (da) 1985-10-21

Family

ID=6010286

Family Applications (1)

Application Number Title Priority Date Filing Date
DK239378A DK148233C (da) 1977-05-31 1978-05-30 Analogifremgangsmaade til fremstilling af 5,11-dihydro-6h-pyrido-(2,3-b)(1,4)benzodiazepin-6-oner, der er substitueret i 11-stillingen, eller salte deraf

Country Status (30)

Country Link
US (1) US4210648A (da)
JP (1) JPS543092A (da)
AT (1) AT361929B (da)
AU (1) AU516712B2 (da)
BE (1) BE867639A (da)
BG (1) BG28712A3 (da)
CA (1) CA1081220A (da)
CH (1) CH637956A5 (da)
CS (1) CS202600B2 (da)
DD (1) DD135490A5 (da)
DK (1) DK148233C (da)
ES (1) ES470269A1 (da)
FI (1) FI63233C (da)
FR (1) FR2392991A1 (da)
GB (1) GB1581500A (da)
GR (1) GR64535B (da)
HK (1) HK19381A (da)
HU (1) HU180540B (da)
IE (1) IE46909B1 (da)
IL (1) IL54815A (da)
MY (1) MY8100362A (da)
NL (1) NL7805848A (da)
NO (1) NO149065C (da)
NZ (1) NZ187428A (da)
PL (1) PL113999B1 (da)
PT (1) PT68114A (da)
SE (1) SE437831B (da)
SU (1) SU797578A3 (da)
YU (1) YU129478A (da)
ZA (1) ZA783086B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2053187A (en) * 1979-07-09 1981-02-04 Grissmann Chem Ltd Process for preparing pyrenzepine
GR72993B (da) * 1980-01-24 1984-01-25 Crc Ricerca Chim
IT1130973B (it) * 1980-03-17 1986-06-18 Microsules Argentina Sa De S C Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one,derivati finali ed intermedi di sintesi in tal modo ottenuti
DE3212794A1 (de) * 1982-04-06 1983-10-13 Basf Ag, 6700 Ludwigshafen 5,6-dihydro-11-alkylen-morphantridin-6-one, ihre herstellung und diese enthaltende arzneimittel
IT1212743B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Sali quaternari di derivati di benzo[ 1,4 ]diazepinonici,pirido [1,4]benzodiazepinonici,prido [1,5]benzodiazepinonici e loro atti vita' farmacologica
IT1212742B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Derivati dibenzo [1,4]diazepinonici pirido [1,4] benzodiazepinonici,pirido [1,5] benzodiazepinonici e loro attivita' farmacologica
DE3626095A1 (de) * 1986-07-31 1988-02-11 Thomae Gmbh Dr K Neue substituierte pyrido(2,3-b)(1,4)benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3643666A1 (de) * 1986-12-20 1988-06-30 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3802334A1 (de) * 1988-01-27 1989-08-10 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820347A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Verwendung von in 11-stellung substituierten 5,11-dihydro-6h-pyrido(2,3-b) (1,4)benzodiazepin-6-onen zur behandlung von bradycardien und bradyarrhythmien in der human- und veterinaermedizin
DE3820346A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5264432A (en) * 1989-07-31 1993-11-23 Arzneimittelwerk Dresden G.M.B.H 5-(1-aminoacyl)-5,10-dihydro-11H-dibenzo[b,e](1,4)diazepin-11-ones
DE3930262A1 (de) * 1989-09-11 1991-03-21 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3930266A1 (de) * 1989-09-11 1991-03-14 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB9000302D0 (en) * 1990-01-06 1990-03-07 Pfizer Ltd Muscarinic receptor antagonists
US5418229A (en) * 1990-01-06 1995-05-23 Alker; David Muscarinic receptor antagonists
CA2573673A1 (en) 2004-07-16 2006-01-26 Proteosys Ag Muscarinic antagonists with parp and sir modulating activity as cytoprotective agents
EP2379080A1 (en) 2009-01-13 2011-10-26 ProteoSys AG Pirenzepine as otoprotective agent

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795183B1 (de) * 1968-08-20 1972-07-20 Thomae Gmbh Dr K 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel
US3691152A (en) * 1971-03-10 1972-09-12 Texaco Inc Hydrodesulfurization and blending of residue-containing petroleum oil

Also Published As

Publication number Publication date
GB1581500A (en) 1980-12-17
SE437831B (sv) 1985-03-18
IL54815A (en) 1981-07-31
IE781073L (en) 1978-11-30
DK148233B (da) 1985-05-13
ATA367778A (de) 1980-09-15
DD135490A5 (de) 1979-05-09
SE7806287L (sv) 1978-12-01
NZ187428A (en) 1981-01-23
AU516712B2 (en) 1981-06-18
SU797578A3 (ru) 1981-01-15
AU3662478A (en) 1979-12-06
JPS6216952B2 (da) 1987-04-15
FI63233B (fi) 1983-01-31
JPS543092A (en) 1979-01-11
NL7805848A (nl) 1978-12-04
FR2392991A1 (fr) 1978-12-29
BE867639A (fr) 1978-11-30
MY8100362A (en) 1981-12-31
PT68114A (de) 1978-06-01
NO149065C (no) 1984-02-08
PL113999B1 (en) 1981-01-31
GR64535B (en) 1980-04-10
CS202600B2 (en) 1981-01-30
HK19381A (en) 1981-05-15
US4210648A (en) 1980-07-01
YU129478A (en) 1983-02-28
FI63233C (fi) 1983-05-10
NO781880L (no) 1978-12-01
ZA783086B (en) 1980-02-27
ES470269A1 (es) 1979-01-01
BG28712A3 (bg) 1980-06-16
IE46909B1 (en) 1983-11-02
AT361929B (de) 1981-04-10
PL207192A1 (pl) 1979-04-23
FI781690A7 (fi) 1978-12-01
NO149065B (no) 1983-10-31
CA1081220A (en) 1980-07-08
HU180540B (en) 1983-03-28
FR2392991B1 (da) 1982-10-22
DK148233C (da) 1985-10-21
CH637956A5 (de) 1983-08-31

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