JPS543092A - Novel benzodiazepine derivatives - Google Patents

Novel benzodiazepine derivatives

Info

Publication number
JPS543092A
JPS543092A JP6484378A JP6484378A JPS543092A JP S543092 A JPS543092 A JP S543092A JP 6484378 A JP6484378 A JP 6484378A JP 6484378 A JP6484378 A JP 6484378A JP S543092 A JPS543092 A JP S543092A
Authority
JP
Japan
Prior art keywords
benzodiazepine derivatives
novel benzodiazepine
novel
derivatives
benzodiazepine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6484378A
Other languages
English (en)
Other versions
JPS6216952B2 (ja
Inventor
Shiyumitsuto Giyuntaa
Reitorudo Matsutoyasu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2724478A external-priority patent/DE2724478C2/de
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of JPS543092A publication Critical patent/JPS543092A/ja
Publication of JPS6216952B2 publication Critical patent/JPS6216952B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP6484378A 1977-05-31 1978-05-30 Novel benzodiazepine derivatives Granted JPS543092A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2724478A DE2724478C2 (de) 1977-05-31 1977-05-31 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
JPS543092A true JPS543092A (en) 1979-01-11
JPS6216952B2 JPS6216952B2 (ja) 1987-04-15

Family

ID=6010286

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6484378A Granted JPS543092A (en) 1977-05-31 1978-05-30 Novel benzodiazepine derivatives

Country Status (30)

Country Link
US (1) US4210648A (ja)
JP (1) JPS543092A (ja)
AT (1) AT361929B (ja)
AU (1) AU516712B2 (ja)
BE (1) BE867639A (ja)
BG (1) BG28712A3 (ja)
CA (1) CA1081220A (ja)
CH (1) CH637956A5 (ja)
CS (1) CS202600B2 (ja)
DD (1) DD135490A5 (ja)
DK (1) DK148233C (ja)
ES (1) ES470269A1 (ja)
FI (1) FI63233C (ja)
FR (1) FR2392991A1 (ja)
GB (1) GB1581500A (ja)
GR (1) GR64535B (ja)
HK (1) HK19381A (ja)
HU (1) HU180540B (ja)
IE (1) IE46909B1 (ja)
IL (1) IL54815A (ja)
MY (1) MY8100362A (ja)
NL (1) NL7805848A (ja)
NO (1) NO149065C (ja)
NZ (1) NZ187428A (ja)
PL (1) PL113999B1 (ja)
PT (1) PT68114A (ja)
SE (1) SE437831B (ja)
SU (1) SU797578A3 (ja)
YU (1) YU129478A (ja)
ZA (1) ZA783086B (ja)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2053187A (en) * 1979-07-09 1981-02-04 Grissmann Chem Ltd Process for preparing pyrenzepine
GR72993B (ja) * 1980-01-24 1984-01-25 Crc Ricerca Chim
IT1130973B (it) * 1980-03-17 1986-06-18 Microsules Argentina Sa De S C Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one,derivati finali ed intermedi di sintesi in tal modo ottenuti
DE3212794A1 (de) * 1982-04-06 1983-10-13 Basf Ag, 6700 Ludwigshafen 5,6-dihydro-11-alkylen-morphantridin-6-one, ihre herstellung und diese enthaltende arzneimittel
IT1212743B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Sali quaternari di derivati di benzo[ 1,4 ]diazepinonici,pirido [1,4]benzodiazepinonici,prido [1,5]benzodiazepinonici e loro atti vita' farmacologica
IT1212742B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Derivati dibenzo [1,4]diazepinonici pirido [1,4] benzodiazepinonici,pirido [1,5] benzodiazepinonici e loro attivita' farmacologica
DE3626095A1 (de) * 1986-07-31 1988-02-11 Thomae Gmbh Dr K Neue substituierte pyrido(2,3-b)(1,4)benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3643666A1 (de) * 1986-12-20 1988-06-30 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3802334A1 (de) * 1988-01-27 1989-08-10 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820346A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820347A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Verwendung von in 11-stellung substituierten 5,11-dihydro-6h-pyrido(2,3-b) (1,4)benzodiazepin-6-onen zur behandlung von bradycardien und bradyarrhythmien in der human- und veterinaermedizin
US5264432A (en) * 1989-07-31 1993-11-23 Arzneimittelwerk Dresden G.M.B.H 5-(1-aminoacyl)-5,10-dihydro-11H-dibenzo[b,e](1,4)diazepin-11-ones
DE3930266A1 (de) * 1989-09-11 1991-03-14 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3930262A1 (de) * 1989-09-11 1991-03-21 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB9000302D0 (en) * 1990-01-06 1990-03-07 Pfizer Ltd Muscarinic receptor antagonists
US5418229A (en) * 1990-01-06 1995-05-23 Alker; David Muscarinic receptor antagonists
EP1768674A1 (en) 2004-07-16 2007-04-04 ProteoSys AG Muscarinic antagonists with parp and sir modulating activity as cytoprotective agents
WO2010081823A1 (en) 2009-01-13 2010-07-22 Proteosys Ag Pirenzepine as otoprotective agent

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795183B1 (de) * 1968-08-20 1972-07-20 Thomae Gmbh Dr K 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel
US3691152A (en) * 1971-03-10 1972-09-12 Texaco Inc Hydrodesulfurization and blending of residue-containing petroleum oil

Also Published As

Publication number Publication date
SE437831B (sv) 1985-03-18
NO149065B (no) 1983-10-31
PL207192A1 (pl) 1979-04-23
SE7806287L (sv) 1978-12-01
IE46909B1 (en) 1983-11-02
IL54815A (en) 1981-07-31
CH637956A5 (de) 1983-08-31
NZ187428A (en) 1981-01-23
HK19381A (en) 1981-05-15
AT361929B (de) 1981-04-10
DD135490A5 (de) 1979-05-09
BE867639A (fr) 1978-11-30
IE781073L (en) 1978-11-30
PT68114A (de) 1978-06-01
BG28712A3 (en) 1980-06-16
FI63233B (fi) 1983-01-31
HU180540B (en) 1983-03-28
ATA367778A (de) 1980-09-15
ES470269A1 (es) 1979-01-01
NO149065C (no) 1984-02-08
PL113999B1 (en) 1981-01-31
ZA783086B (en) 1980-02-27
DK148233B (da) 1985-05-13
GR64535B (en) 1980-04-10
GB1581500A (en) 1980-12-17
DK148233C (da) 1985-10-21
FR2392991A1 (fr) 1978-12-29
NO781880L (no) 1978-12-01
US4210648A (en) 1980-07-01
CS202600B2 (en) 1981-01-30
CA1081220A (en) 1980-07-08
FI63233C (fi) 1983-05-10
FR2392991B1 (ja) 1982-10-22
AU3662478A (en) 1979-12-06
DK239378A (da) 1978-12-01
MY8100362A (en) 1981-12-31
AU516712B2 (en) 1981-06-18
JPS6216952B2 (ja) 1987-04-15
YU129478A (en) 1983-02-28
NL7805848A (nl) 1978-12-04
FI781690A (fi) 1978-12-01
SU797578A3 (ru) 1981-01-15

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