DK148233C - Analogifremgangsmaade til fremstilling af 5,11-dihydro-6h-pyrido-(2,3-b)(1,4)benzodiazepin-6-oner, der er substitueret i 11-stillingen, eller salte deraf - Google Patents

Analogifremgangsmaade til fremstilling af 5,11-dihydro-6h-pyrido-(2,3-b)(1,4)benzodiazepin-6-oner, der er substitueret i 11-stillingen, eller salte deraf

Info

Publication number
DK148233C
DK148233C DK239378A DK239378A DK148233C DK 148233 C DK148233 C DK 148233C DK 239378 A DK239378 A DK 239378A DK 239378 A DK239378 A DK 239378A DK 148233 C DK148233 C DK 148233C
Authority
DK
Denmark
Prior art keywords
benzodiazepin
pyrido
dihydro
analogue
salts
Prior art date
Application number
DK239378A
Other languages
English (en)
Other versions
DK239378A (da
DK148233B (da
Inventor
Guenther Schmidt
Matyas Leitold
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2724478A external-priority patent/DE2724478C2/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DK239378A publication Critical patent/DK239378A/da
Publication of DK148233B publication Critical patent/DK148233B/da
Application granted granted Critical
Publication of DK148233C publication Critical patent/DK148233C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK239378A 1977-05-31 1978-05-30 Analogifremgangsmaade til fremstilling af 5,11-dihydro-6h-pyrido-(2,3-b)(1,4)benzodiazepin-6-oner, der er substitueret i 11-stillingen, eller salte deraf DK148233C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2724478A DE2724478C2 (de) 1977-05-31 1977-05-31 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2724478 1977-05-31

Publications (3)

Publication Number Publication Date
DK239378A DK239378A (da) 1978-12-01
DK148233B DK148233B (da) 1985-05-13
DK148233C true DK148233C (da) 1985-10-21

Family

ID=6010286

Family Applications (1)

Application Number Title Priority Date Filing Date
DK239378A DK148233C (da) 1977-05-31 1978-05-30 Analogifremgangsmaade til fremstilling af 5,11-dihydro-6h-pyrido-(2,3-b)(1,4)benzodiazepin-6-oner, der er substitueret i 11-stillingen, eller salte deraf

Country Status (30)

Country Link
US (1) US4210648A (da)
JP (1) JPS543092A (da)
AT (1) AT361929B (da)
AU (1) AU516712B2 (da)
BE (1) BE867639A (da)
BG (1) BG28712A3 (da)
CA (1) CA1081220A (da)
CH (1) CH637956A5 (da)
CS (1) CS202600B2 (da)
DD (1) DD135490A5 (da)
DK (1) DK148233C (da)
ES (1) ES470269A1 (da)
FI (1) FI63233C (da)
FR (1) FR2392991A1 (da)
GB (1) GB1581500A (da)
GR (1) GR64535B (da)
HK (1) HK19381A (da)
HU (1) HU180540B (da)
IE (1) IE46909B1 (da)
IL (1) IL54815A (da)
MY (1) MY8100362A (da)
NL (1) NL7805848A (da)
NO (1) NO149065C (da)
NZ (1) NZ187428A (da)
PL (1) PL113999B1 (da)
PT (1) PT68114A (da)
SE (1) SE437831B (da)
SU (1) SU797578A3 (da)
YU (1) YU129478A (da)
ZA (1) ZA783086B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2053187A (en) * 1979-07-09 1981-02-04 Grissmann Chem Ltd Process for preparing pyrenzepine
GR72993B (da) * 1980-01-24 1984-01-25 Crc Ricerca Chim
IT1130973B (it) * 1980-03-17 1986-06-18 Microsules Argentina Sa De S C Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one,derivati finali ed intermedi di sintesi in tal modo ottenuti
DE3212794A1 (de) * 1982-04-06 1983-10-13 Basf Ag, 6700 Ludwigshafen 5,6-dihydro-11-alkylen-morphantridin-6-one, ihre herstellung und diese enthaltende arzneimittel
IT1212742B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Derivati dibenzo [1,4]diazepinonici pirido [1,4] benzodiazepinonici,pirido [1,5] benzodiazepinonici e loro attivita' farmacologica
IT1212743B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Sali quaternari di derivati di benzo[ 1,4 ]diazepinonici,pirido [1,4]benzodiazepinonici,prido [1,5]benzodiazepinonici e loro atti vita' farmacologica
DE3626095A1 (de) * 1986-07-31 1988-02-11 Thomae Gmbh Dr K Neue substituierte pyrido(2,3-b)(1,4)benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3643666A1 (de) * 1986-12-20 1988-06-30 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3802334A1 (de) * 1988-01-27 1989-08-10 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820346A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820347A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Verwendung von in 11-stellung substituierten 5,11-dihydro-6h-pyrido(2,3-b) (1,4)benzodiazepin-6-onen zur behandlung von bradycardien und bradyarrhythmien in der human- und veterinaermedizin
US5264432A (en) * 1989-07-31 1993-11-23 Arzneimittelwerk Dresden G.M.B.H 5-(1-aminoacyl)-5,10-dihydro-11H-dibenzo[b,e](1,4)diazepin-11-ones
DE3930266A1 (de) * 1989-09-11 1991-03-14 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3930262A1 (de) * 1989-09-11 1991-03-21 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5418229A (en) * 1990-01-06 1995-05-23 Alker; David Muscarinic receptor antagonists
GB9000302D0 (en) * 1990-01-06 1990-03-07 Pfizer Ltd Muscarinic receptor antagonists
KR20070033032A (ko) 2004-07-16 2007-03-23 프로테오시스 악티엔게젤샤프트 세포보호제로서 parp 및 sir 조절 활성을 갖는무스카린 길항제
EP2387405A2 (en) 2009-01-13 2011-11-23 ProteoSys AG Pirenzepine as an agent in cancer treatment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795183B1 (de) * 1968-08-20 1972-07-20 Thomae Gmbh Dr K 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel
US3691152A (en) * 1971-03-10 1972-09-12 Texaco Inc Hydrodesulfurization and blending of residue-containing petroleum oil

Also Published As

Publication number Publication date
FI63233C (fi) 1983-05-10
IE781073L (en) 1978-11-30
HK19381A (en) 1981-05-15
NO149065C (no) 1984-02-08
US4210648A (en) 1980-07-01
PL113999B1 (en) 1981-01-31
NL7805848A (nl) 1978-12-04
GR64535B (en) 1980-04-10
CA1081220A (en) 1980-07-08
IE46909B1 (en) 1983-11-02
NZ187428A (en) 1981-01-23
ATA367778A (de) 1980-09-15
MY8100362A (en) 1981-12-31
DK239378A (da) 1978-12-01
NO149065B (no) 1983-10-31
SU797578A3 (ru) 1981-01-15
JPS543092A (en) 1979-01-11
DD135490A5 (de) 1979-05-09
FR2392991A1 (fr) 1978-12-29
FI781690A (fi) 1978-12-01
GB1581500A (en) 1980-12-17
CS202600B2 (en) 1981-01-30
NO781880L (no) 1978-12-01
CH637956A5 (de) 1983-08-31
FI63233B (fi) 1983-01-31
SE437831B (sv) 1985-03-18
ES470269A1 (es) 1979-01-01
YU129478A (en) 1983-02-28
AU3662478A (en) 1979-12-06
AU516712B2 (en) 1981-06-18
FR2392991B1 (da) 1982-10-22
SE7806287L (sv) 1978-12-01
BE867639A (fr) 1978-11-30
BG28712A3 (en) 1980-06-16
JPS6216952B2 (da) 1987-04-15
PL207192A1 (pl) 1979-04-23
IL54815A (en) 1981-07-31
PT68114A (de) 1978-06-01
HU180540B (en) 1983-03-28
ZA783086B (en) 1980-02-27
AT361929B (de) 1981-04-10
DK148233B (da) 1985-05-13

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