DK165005C - Analogifremgangsmaade til fremstilling af 4,5-dihydro-4-oxofuran-2-carboxylsyrederivater eller terapeutisk acceptable salte deraf - Google Patents
Analogifremgangsmaade til fremstilling af 4,5-dihydro-4-oxofuran-2-carboxylsyrederivater eller terapeutisk acceptable salte derafInfo
- Publication number
- DK165005C DK165005C DK037580A DK37580A DK165005C DK 165005 C DK165005 C DK 165005C DK 037580 A DK037580 A DK 037580A DK 37580 A DK37580 A DK 37580A DK 165005 C DK165005 C DK 165005C
- Authority
- DK
- Denmark
- Prior art keywords
- oxofuran
- dihydro
- analogue
- preparation
- carboxylic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/28—Alcohols containing only six-membered aromatic rings as cyclic part with unsaturation outside the aromatic rings
- C07C33/30—Alcohols containing only six-membered aromatic rings as cyclic part with unsaturation outside the aromatic rings monocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/31—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with compounds containing mercury atoms, which may be regenerated in situ, e.g. by oxygen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/912,798 US4169202A (en) | 1978-06-05 | 1978-06-05 | Process for preparing 4,5-dihydro-4-oxofuran-2-carboxylic acid derivatives |
| US91279878 | 1978-06-05 | ||
| PCT/US1979/000376 WO1980000025A1 (en) | 1978-06-05 | 1979-05-29 | Derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic acid,preparations and use thereof and tetrahydropyran-2,3,5-trione intermediates |
| US7900376 | 1979-05-29 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK37580A DK37580A (da) | 1980-01-29 |
| DK165005B DK165005B (da) | 1992-09-28 |
| DK165005C true DK165005C (da) | 1993-02-08 |
Family
ID=25432464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK037580A DK165005C (da) | 1978-06-05 | 1980-01-29 | Analogifremgangsmaade til fremstilling af 4,5-dihydro-4-oxofuran-2-carboxylsyrederivater eller terapeutisk acceptable salte deraf |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4169202A (da) |
| EP (1) | EP0006305B1 (da) |
| JP (1) | JPS648629B2 (da) |
| AU (1) | AU537177B2 (da) |
| CA (1) | CA1118777A (da) |
| CY (1) | CY1305A (da) |
| DE (1) | DE2963526D1 (da) |
| DK (1) | DK165005C (da) |
| ES (1) | ES8100283A1 (da) |
| HK (1) | HK76785A (da) |
| HU (1) | HU180199B (da) |
| MY (1) | MY8600277A (da) |
| PH (1) | PH15720A (da) |
| WO (1) | WO1980000025A1 (da) |
| ZA (1) | ZA792773B (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1173037A (en) * | 1980-03-01 | 1984-08-21 | John L. Archibald | Piperidino ureas as antidepressants |
| DE3141194A1 (de) * | 1981-10-16 | 1983-05-11 | Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München | Verbundwerkstoff und verfahren zu seiner herstellung |
| JPS58175487A (ja) * | 1982-04-08 | 1983-10-14 | Meito Sangyo Kk | 改質微生物レンネツト及びその製法 |
| US4537623A (en) * | 1984-03-29 | 1985-08-27 | Chevron Research Company | Herbicidal 2-(oxa or thia heterocycle)5-amino-3-oxo-4-(substituted-phenyl)-2,3-dihydrofurans |
| JPS63500375A (ja) * | 1985-08-02 | 1988-02-12 | シエブロン リサ−チ カンパニ− | 除草性２−（オクサまたはチアヘテロサイクル）５−アミノ−３−オクソ−４−（置換−フェニル）−２、３−ジヒドロフラン類 |
| US4704475A (en) * | 1986-06-02 | 1987-11-03 | American Home Products Corporation (Del.) | Preparation of 3-hydroxy-3-phenylbutan-2-one |
| JPH0753678B2 (ja) * | 1986-07-25 | 1995-06-07 | ダイセル化学工業株式会社 | アセトイン誘導体の直接光学分割方法 |
| WO2003018575A1 (en) * | 2001-08-24 | 2003-03-06 | Wyeth Holdings Corporation | 5-substituted-3(2h)-furanones useful for inhibition of farnesyl-protein transferase |
| ES2331521T3 (es) * | 2003-11-21 | 2010-01-07 | Arena Pharmaceuticals, Inc. | Derivados de acido 4-oxo-4,5-dihidro-furan-2-carboxilico y procedimientos de tratamiento de trastornos metabolicos relacionados del mismo. |
| EP3049397A1 (en) * | 2013-09-27 | 2016-08-03 | Sun Pharmaceutical Industries Ltd | Process for the purification of dapagliflozin |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2436532A (en) * | 1945-02-24 | 1948-02-24 | Robertson Co H H | Production of 4-keto pimelic acid |
| US2744917A (en) * | 1950-06-30 | 1956-05-08 | Lilly Co Eli | Process for the preparation of thiophene dicarboxylic acid |
| US2745845A (en) * | 1950-06-30 | 1956-05-15 | Lilly Co Eli | 1-formyl-2-dialkoxymethyl-succinic acid esters and their cyclization to heterocyclic compounds |
| US3344150A (en) * | 1962-04-18 | 1967-09-26 | Technion Res & Dev Foundation | 6-substituted 2, 3, 5-trioxo-tetrahydropyrans and their 3-enol esters and ethers |
| US3393204A (en) * | 1963-04-23 | 1968-07-16 | Cais Michael | Heterocyclic compound and use |
| DE1518369A1 (de) * | 1965-01-28 | 1969-11-06 | Technion Res & Dev Foundation | 4-Halogen-3,5,6-trioxotetrahydropyrane und Verfahren zu ihrer Herstellung |
| US3439000A (en) * | 1965-10-06 | 1969-04-15 | Richardson Merrell Inc | Aldehydes and ketones of trifluoromethylfurans |
| US3442913A (en) * | 1965-10-06 | 1969-05-06 | Richardson Merrell Inc | 2-(trifluoromethyl)-3-fuoricacid esters and other 2 - fluoromethyl furan derivatives |
| US3393206A (en) * | 1966-02-15 | 1968-07-16 | Cais Michael | Heterocyclic compound and use |
| US3393205A (en) * | 1966-02-15 | 1968-07-16 | Cais Michael | Heterocyclic compound and use |
| GB1199101A (en) * | 1967-03-15 | 1970-07-15 | Ajinomoto Kk | Substance and Reaction Products Suitable for Improving the Flavour and Aroma of Food and Medicines |
| CH474500A (fr) * | 1967-06-16 | 1969-06-30 | Firmenich & Cie | Procédé pour la préparation d'un dérivé furannique |
| NL6712748A (da) * | 1967-09-18 | 1969-03-20 | ||
| US3887589A (en) * | 1968-03-28 | 1975-06-03 | Lever Brothers Ltd | 2,5-Diethyl-4-hydroxy-2,3,-dihydrofuran-3-one |
| GB1271082A (en) * | 1968-05-07 | 1972-04-19 | Wyeth John & Brother Ltd | Furan, pyrrole and thiophene derivatives |
| US3743656A (en) * | 1969-05-01 | 1973-07-03 | Wyeth John & Brother Ltd | Thiophene and furan lower alkanoic acids and derivatives |
| US3904655A (en) * | 1969-06-26 | 1975-09-09 | Lever Brothers Ltd | Process for the preparation of a flavor substance by reacting a 4-oxy-5-alkyl-3-furanone with a hydrogen sulfide liberating substance |
| DE2013261A1 (de) * | 1970-03-20 | 1971-10-07 | Badische Anilin & Soda Fabnk AG, 6700 Ludwigshafen | Verfahren zur Herstellung von Furanen |
| GB1383492A (en) * | 1970-12-21 | 1974-02-12 | Unilever Ltd | Dicarbonyl compounds and preparation of dihydrofuranones therefrom |
| NL7216271A (da) * | 1972-11-30 | 1974-06-04 | ||
| US4000164A (en) * | 1973-04-02 | 1976-12-28 | Richardson-Merrell Inc. | Hypolipidemic agents |
| GB1489734A (en) * | 1975-04-08 | 1977-10-26 | Nippon Chemiphar Co | Ascorbic acid derivative and pharmaceutical compositions containing the same |
-
1978
- 1978-06-05 US US05/912,798 patent/US4169202A/en not_active Expired - Lifetime
-
1979
- 1979-05-09 AU AU46892/79A patent/AU537177B2/en not_active Expired
- 1979-05-24 CY CY1305A patent/CY1305A/xx unknown
- 1979-05-24 EP EP79300928A patent/EP0006305B1/en not_active Expired
- 1979-05-24 DE DE7979300928T patent/DE2963526D1/de not_active Expired
- 1979-05-29 WO PCT/US1979/000376 patent/WO1980000025A1/en unknown
- 1979-05-29 JP JP54500920A patent/JPS648629B2/ja not_active Expired
- 1979-05-31 CA CA000328790A patent/CA1118777A/en not_active Expired
- 1979-06-04 ES ES481233A patent/ES8100283A1/es not_active Expired
- 1979-06-05 PH PH22607A patent/PH15720A/en unknown
- 1979-06-05 ZA ZA792773A patent/ZA792773B/xx unknown
- 1979-06-05 HU HU79AE575A patent/HU180199B/hu not_active IP Right Cessation
-
1980
- 1980-01-29 DK DK037580A patent/DK165005C/da not_active IP Right Cessation
-
1985
- 1985-10-10 HK HK767/85A patent/HK76785A/xx unknown
-
1986
- 1986-12-30 MY MY277/86A patent/MY8600277A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES481233A0 (es) | 1980-11-01 |
| ES8100283A1 (es) | 1980-11-01 |
| DK165005B (da) | 1992-09-28 |
| CY1305A (en) | 1985-12-06 |
| EP0006305B1 (en) | 1982-08-11 |
| DE2963526D1 (en) | 1982-10-07 |
| MY8600277A (en) | 1986-12-31 |
| EP0006305A1 (en) | 1980-01-09 |
| DK37580A (da) | 1980-01-29 |
| AU4689279A (en) | 1979-12-13 |
| HU180199B (en) | 1983-02-28 |
| PH15720A (en) | 1983-03-18 |
| WO1980000025A1 (en) | 1980-01-10 |
| JPS55500473A (da) | 1980-07-31 |
| AU537177B2 (en) | 1984-06-14 |
| HK76785A (en) | 1985-10-18 |
| ZA792773B (en) | 1981-01-28 |
| US4169202A (en) | 1979-09-25 |
| JPS648629B2 (da) | 1989-02-14 |
| CA1118777A (en) | 1982-02-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment | ||
| PBP | Patent lapsed |