DK145339C - Analogifremgangsmaade til fremstilling af 4-amino-5-hexensyre eller farmaceutisk acceptable salte deraf - Google Patents
Analogifremgangsmaade til fremstilling af 4-amino-5-hexensyre eller farmaceutisk acceptable salte derafInfo
- Publication number
- DK145339C DK145339C DK31476A DK31476A DK145339C DK 145339 C DK145339 C DK 145339C DK 31476 A DK31476 A DK 31476A DK 31476 A DK31476 A DK 31476A DK 145339 C DK145339 C DK 145339C
- Authority
- DK
- Denmark
- Prior art keywords
- analogue
- amino
- preparation
- acceptable salts
- pharmaceutical acceptable
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title 1
- PJDFLNIOAUIZSL-UHFFFAOYSA-N vigabatrin Chemical compound C=CC(N)CCC(O)=O PJDFLNIOAUIZSL-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/559,544 US3960927A (en) | 1975-03-18 | 1975-03-18 | Olefinic derivatives of amino acids |
| US55954475 | 1975-03-18 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK31476A DK31476A (da) | 1976-09-19 |
| DK145339B DK145339B (da) | 1982-11-01 |
| DK145339C true DK145339C (da) | 1983-03-21 |
Family
ID=24233995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK31476A DK145339C (da) | 1975-03-18 | 1976-01-27 | Analogifremgangsmaade til fremstilling af 4-amino-5-hexensyre eller farmaceutisk acceptable salte deraf |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US3960927A (da) |
| JP (1) | JPS593988B2 (da) |
| BE (1) | BE839657A (da) |
| CA (1) | CA1077487A (da) |
| CH (1) | CH631696A5 (da) |
| DE (1) | DE2607620C2 (da) |
| DK (1) | DK145339C (da) |
| ES (1) | ES445659A1 (da) |
| FR (1) | FR2304329A1 (da) |
| GB (1) | GB1472525A (da) |
| IE (1) | IE42410B1 (da) |
| IL (1) | IL48912A (da) |
| MX (1) | MX4654E (da) |
| NL (2) | NL187161C (da) |
| NO (1) | NO146428C (da) |
| NZ (1) | NZ179834A (da) |
| PH (1) | PH12100A (da) |
| PT (1) | PT64761B (da) |
| SE (1) | SE442295B (da) |
| ZA (1) | ZA76411B (da) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4039549A (en) * | 1975-03-18 | 1977-08-02 | Merrell Toraude Et Compagnie | Olefinic derivatives of amino acids |
| US4041041A (en) * | 1975-03-18 | 1977-08-09 | Merrell Toraude Et Compagnie | Acetylene derivatives of amino acids |
| US4139563A (en) * | 1977-07-01 | 1979-02-13 | Merrell Toraude Et Compagnie | α-ACETYLENIC DERIVATIVES OF AMINES |
| CA1121375A (en) * | 1977-07-01 | 1982-04-06 | Brian W. Metcalf | Derivatives of amines and amino acids |
| US4147873A (en) * | 1977-07-01 | 1979-04-03 | Merrell Toraude Et Compagnie | α-Vinyl derivatives of α-amino acids |
| CA1157030A (en) * | 1977-07-01 | 1983-11-15 | Brian W. Metcalf | .alpha.-VINYL AMINO ACIDS |
| US4326071A (en) * | 1977-09-28 | 1982-04-20 | Merrell Toraude Et Compagnie | Halomethyl derivatives of gamma-aminobutyric acid and related compounds |
| US4187316A (en) * | 1978-01-12 | 1980-02-05 | Merrell Toraude Et Compagnie | Substituted 1,5-cyclohexadiene carboxylic acid derivatives |
| US4254284A (en) * | 1978-01-30 | 1981-03-03 | Merrell Toraude Et Compagnie | Process for preparing 4-aminohex-5-ynoic acid |
| US4178463A (en) * | 1978-01-30 | 1979-12-11 | Merrell Toraude Et Compagnie | Process for making 4-aminohex-5-enoic acid |
| US5147868A (en) * | 1978-07-24 | 1992-09-15 | Merck & Co., Inc. | Thienamycin renal peptidase inhibitors |
| US4880793A (en) * | 1978-07-24 | 1989-11-14 | Merck & Co., Inc. | Combination of thienamycin-type antibiotics with dipeptidase inhibitors |
| US4323704A (en) * | 1979-06-25 | 1982-04-06 | Merrell Toraude Et Compagnie | αAcetylene and α-vinyl derivatives of amino acids |
| US4539208A (en) * | 1980-09-17 | 1985-09-03 | Merck & Co., Inc. | Combination of thienamycin-type antibiotics with dipeptidase inhibitors |
| US4372974A (en) * | 1980-06-25 | 1983-02-08 | New York University | Anticonvulsive compositions and method of treating convulsive disorders |
| GB2120244B (en) * | 1982-05-17 | 1985-05-01 | Merrell Toraude & Co | Aminoalkadiene derivative |
| GB2133002B (en) * | 1982-12-30 | 1986-01-29 | Merrell Toraude & Co | Process for preparing 4-amino-5-hexenoic acid |
| GB8311804D0 (en) * | 1983-04-29 | 1983-06-02 | Merrell Toraude & Co | Treatment of seizure disorders and pharmaceutical compositions |
| US4668703A (en) * | 1983-07-07 | 1987-05-26 | Syntex (U.S.A.) Inc. | γ-allenyl-γ-aminobutyric acids |
| EP0134481B1 (en) * | 1983-07-07 | 1987-12-16 | Syntex (U.S.A.) Inc. | Gamma-allenyl-gamma-aminobutyric acids |
| US4661510A (en) * | 1983-08-17 | 1987-04-28 | Syntex (U.S.A.) Inc. | α-allenic-α-amino acids as enzyme inhibitors |
| US4588825A (en) * | 1983-10-11 | 1986-05-13 | Merrell Dow Pharmaceuticals Inc. | Intermediates for the synthesis of 4-amino-4,5-dihydro-2-furancarboxylic acid |
| US4632994A (en) * | 1983-11-04 | 1986-12-30 | Gruppo Lepetit S.P.A. | Process for decomposing N-oxide derivatives producing 5-vinyl-2-pyrrolidones |
| JPS6137389U (ja) * | 1984-08-09 | 1986-03-08 | 永大産業株式会社 | 家具用の戸 |
| DE3536146A1 (de) * | 1985-10-10 | 1987-04-16 | Degussa | Verfahren zur enantioselektiven herstellung von (alpha)-vinyl-(alpha)-aminocarbonsaeuren |
| US4806680A (en) * | 1986-03-17 | 1989-02-21 | Merck & Co., Inc. | 3-halovinylglycine antibacterial agents |
| US4727062A (en) * | 1986-03-17 | 1988-02-23 | Merck & Co., Inc. | 3-Halovinylglycine antibacterial agents |
| CA2028782C (en) * | 1989-11-07 | 2003-10-14 | Christian T. Goralski | Process for the production of vinyl-gaba |
| IL100360A (en) * | 1990-12-17 | 1998-08-16 | Merrell Dow Pharma | HISTORY OF PYROLIDINONE USED AS SUBSTANCE (S) -Vinyl and Alanyl GABA |
| US5208345A (en) * | 1990-12-17 | 1993-05-04 | Merrell Dow Pharmaceuticals Inc. | Process for the production of (S)-vinyl and allenyl gaba |
| EP0546230A1 (en) * | 1991-12-10 | 1993-06-16 | Merrell Dow Pharmaceuticals Inc. | Novel process for preparing 4-amino-5-hexenoic acid |
| US5705660A (en) * | 1994-08-22 | 1998-01-06 | Board Of Regents, University Of Nebraska-Lincoln | Method for the synthesis of α-oxiranyl amino acids |
| US7098206B2 (en) * | 1998-01-21 | 2006-08-29 | Smithkline Beecham Corporation | Pharmaceutically active morpholinol |
| US6998400B2 (en) * | 1998-01-22 | 2006-02-14 | Smithkline Beecham Corporation | Pharmaceutically active morpholinol |
| US6110973A (en) * | 1998-01-29 | 2000-08-29 | Sepracor | Methods for treating obesity and weight gain using optically pure (-)-bupropion |
| JP2002501891A (ja) | 1998-01-29 | 2002-01-22 | セプラコア インコーポレーテッド | 光学的に純粋な（＋）−ビュープロピオンの医薬用途 |
| US6541520B1 (en) | 1998-08-05 | 2003-04-01 | Brookhaven Science Associates | Treatment of addiction and addiction-related behavior |
| US6734213B2 (en) | 1999-01-20 | 2004-05-11 | Smithkline Beecham Corporation | Pharmaceutically active morpholinol |
| US6855820B2 (en) | 1999-01-20 | 2005-02-15 | Smithkline Beecham Corporation | Pharmaceutically active morpholinol |
| US6342496B1 (en) * | 1999-03-01 | 2002-01-29 | Sepracor Inc. | Bupropion metabolites and methods of use |
| US6337328B1 (en) | 1999-03-01 | 2002-01-08 | Sepracor, Inc. | Bupropion metabolites and methods of use |
| WO2002043762A2 (en) | 2000-11-30 | 2002-06-06 | Pfizer Products Inc. | Combination of gaba agonists and sorbitol dehydrogenase inhibitors |
| CA2430309A1 (en) | 2000-11-30 | 2002-06-06 | Pfizer Products Inc. | Combination of gaba agonists and aldose reductase inhibitors |
| CN1791430A (zh) * | 2003-05-16 | 2006-06-21 | 辉瑞产品公司 | 非典型抗精神病药物和gaba调节剂、抗惊厥药物或苯并二氮杂䓬类的治疗性组合 |
| EP2343073A3 (en) | 2003-12-11 | 2011-10-12 | Sepracor Inc. | Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression |
| JP2007537151A (ja) * | 2004-01-29 | 2007-12-20 | ファイザー・プロダクツ・インク | γ−アミノ酪酸モジュレータと５−ＨＴ１Ｂ受容体アンタゴニストとの組合せ |
| AU2006282896A1 (en) | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| EP2258357A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
| WO2007047978A2 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
| JP2009513672A (ja) * | 2005-10-31 | 2009-04-02 | ブレインセルス，インコーポレイティド | 神経発生のｇａｂａ受容体媒介調節 |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| EP2377531A2 (en) | 2006-05-09 | 2011-10-19 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| MX2008014320A (es) | 2006-05-09 | 2009-03-25 | Braincells Inc | Neurogenesis mediada por el receptor de 5-hidroxitriptamina. |
| US7998971B2 (en) | 2006-09-08 | 2011-08-16 | Braincells Inc. | Combinations containing a 4-acylaminopyridine derivative |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| WO2008111096A2 (en) * | 2007-03-15 | 2008-09-18 | Sun Pharma Advanced Research Company Ltd | Novel prodrugs |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| EP2537827B1 (en) | 2011-06-24 | 2014-06-11 | Targeon SAS | Process for preparing 4-amino-5-hexenoic acid from succinimide |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2460708A (en) * | 1946-03-22 | 1949-02-01 | Merck & Co Inc | Process for making acetamido dimethylacrylic acid |
| US2531595A (en) * | 1949-06-09 | 1950-11-28 | Sterling Drug Inc | Preparation of alpha-acylamino-alpha-substituted-acetic acids |
| US2588969A (en) * | 1949-11-26 | 1952-03-11 | Eastman Kodak Co | Certain acylamino-acrylates and-crotonates as insecticides |
| US3223729A (en) * | 1962-06-06 | 1965-12-14 | Sterling Drug Inc | 3-allylhydantoic acid |
-
1975
- 1975-03-18 US US05/559,544 patent/US3960927A/en not_active Expired - Lifetime
-
1976
- 1976-01-23 IE IE136/76A patent/IE42410B1/en unknown
- 1976-01-26 ZA ZA411A patent/ZA76411B/xx unknown
- 1976-01-26 NZ NZ179834A patent/NZ179834A/en unknown
- 1976-01-26 NO NO760234A patent/NO146428C/no unknown
- 1976-01-26 GB GB285676A patent/GB1472525A/en not_active Expired
- 1976-01-27 DK DK31476A patent/DK145339C/da not_active IP Right Cessation
- 1976-01-27 IL IL48912A patent/IL48912A/xx unknown
- 1976-02-02 PT PT64761A patent/PT64761B/pt unknown
- 1976-02-03 PH PH18044A patent/PH12100A/en unknown
- 1976-02-04 NL NLAANVRAGE7601116,A patent/NL187161C/xx active Protection Beyond IP Right Term
- 1976-02-04 SE SE7601205A patent/SE442295B/xx not_active IP Right Cessation
- 1976-02-17 CA CA245,927A patent/CA1077487A/en not_active Expired
- 1976-02-25 DE DE2607620A patent/DE2607620C2/de not_active Expired
- 1976-02-26 JP JP51019522A patent/JPS593988B2/ja not_active Expired
- 1976-02-27 CH CH245476A patent/CH631696A5/de active Protection Beyond IP Right Term
- 1976-02-28 ES ES445659A patent/ES445659A1/es not_active Expired
- 1976-03-02 MX MX7665U patent/MX4654E/es unknown
- 1976-03-16 FR FR7607547A patent/FR2304329A1/fr active Granted
- 1976-03-17 BE BE165245A patent/BE839657A/xx not_active IP Right Cessation
-
1993
- 1993-06-30 NL NL930125C patent/NL930125I2/nl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2304329A1 (fr) | 1976-10-15 |
| CA1077487A (en) | 1980-05-13 |
| PH12100A (en) | 1978-11-02 |
| NO760234L (da) | 1976-09-21 |
| JPS51125320A (en) | 1976-11-01 |
| SE442295B (sv) | 1985-12-16 |
| ZA76411B (en) | 1977-01-26 |
| DE2607620C2 (de) | 1984-09-13 |
| NO146428C (no) | 1982-09-29 |
| IL48912A (en) | 1980-09-16 |
| NL187161C (nl) | 1991-06-17 |
| JPS593988B2 (ja) | 1984-01-27 |
| NL187161B (nl) | 1991-01-16 |
| PT64761A (en) | 1976-03-01 |
| AU1071676A (en) | 1977-08-11 |
| DE2607620A1 (de) | 1976-09-30 |
| GB1472525A (en) | 1977-05-04 |
| NZ179834A (en) | 1978-06-20 |
| ES445659A1 (es) | 1977-06-01 |
| BE839657A (fr) | 1976-07-16 |
| IL48912A0 (en) | 1976-03-31 |
| SE7601205L (sv) | 1976-09-19 |
| DK145339B (da) | 1982-11-01 |
| NL930125I2 (nl) | 1997-08-01 |
| NO146428B (no) | 1982-06-21 |
| FR2304329B1 (da) | 1980-07-18 |
| MX4654E (es) | 1982-07-19 |
| NL7601116A (nl) | 1976-09-21 |
| IE42410B1 (en) | 1980-07-30 |
| NL930125I1 (nl) | 1993-11-01 |
| DK31476A (da) | 1976-09-19 |
| IE42410L (en) | 1976-09-18 |
| CH631696A5 (de) | 1982-08-31 |
| PT64761B (en) | 1977-06-06 |
| US3960927A (en) | 1976-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CTFF | Application for supplementary protection certificate (spc) filed |
Free format text: CA 1993 00048, 930630 |
|
| CTFF | Application for supplementary protection certificate (spc) filed |
Free format text: CA 1993 00048, 930630 |
|
| PUP | Patent expired |