FR2304329A1 - Derives olefiniques d'aminoacides et procede de leur preparation - Google Patents
Derives olefiniques d'aminoacides et procede de leur preparationInfo
- Publication number
- FR2304329A1 FR2304329A1 FR7607547A FR7607547A FR2304329A1 FR 2304329 A1 FR2304329 A1 FR 2304329A1 FR 7607547 A FR7607547 A FR 7607547A FR 7607547 A FR7607547 A FR 7607547A FR 2304329 A1 FR2304329 A1 FR 2304329A1
- Authority
- FR
- France
- Prior art keywords
- aminoacids
- preparation
- olefin derivatives
- olefin
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/559,544 US3960927A (en) | 1975-03-18 | 1975-03-18 | Olefinic derivatives of amino acids |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2304329A1 true FR2304329A1 (fr) | 1976-10-15 |
FR2304329B1 FR2304329B1 (fr) | 1980-07-18 |
Family
ID=24233995
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7607547A Granted FR2304329A1 (fr) | 1975-03-18 | 1976-03-16 | Derives olefiniques d'aminoacides et procede de leur preparation |
Country Status (20)
Country | Link |
---|---|
US (1) | US3960927A (fr) |
JP (1) | JPS593988B2 (fr) |
BE (1) | BE839657A (fr) |
CA (1) | CA1077487A (fr) |
CH (1) | CH631696A5 (fr) |
DE (1) | DE2607620C2 (fr) |
DK (1) | DK145339C (fr) |
ES (1) | ES445659A1 (fr) |
FR (1) | FR2304329A1 (fr) |
GB (1) | GB1472525A (fr) |
IE (1) | IE42410B1 (fr) |
IL (1) | IL48912A (fr) |
MX (1) | MX4654E (fr) |
NL (2) | NL187161C (fr) |
NO (1) | NO146428C (fr) |
NZ (1) | NZ179834A (fr) |
PH (1) | PH12100A (fr) |
PT (1) | PT64761B (fr) |
SE (1) | SE442295B (fr) |
ZA (1) | ZA76411B (fr) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4041041A (en) * | 1975-03-18 | 1977-08-09 | Merrell Toraude Et Compagnie | Acetylene derivatives of amino acids |
US4039549A (en) * | 1975-03-18 | 1977-08-02 | Merrell Toraude Et Compagnie | Olefinic derivatives of amino acids |
CA1157030A (fr) * | 1977-07-01 | 1983-11-15 | Brian W. Metcalf | ACIDES AMINES .alpha.-VINYLIQUES |
US4147873A (en) * | 1977-07-01 | 1979-04-03 | Merrell Toraude Et Compagnie | α-Vinyl derivatives of α-amino acids |
CA1121375A (fr) * | 1977-07-01 | 1982-04-06 | Brian W. Metcalf | Derives d'amines et d'acides amines |
US4139563A (en) * | 1977-07-01 | 1979-02-13 | Merrell Toraude Et Compagnie | α-ACETYLENIC DERIVATIVES OF AMINES |
US4326071A (en) * | 1977-09-28 | 1982-04-20 | Merrell Toraude Et Compagnie | Halomethyl derivatives of gamma-aminobutyric acid and related compounds |
US4187316A (en) * | 1978-01-12 | 1980-02-05 | Merrell Toraude Et Compagnie | Substituted 1,5-cyclohexadiene carboxylic acid derivatives |
US4254284A (en) * | 1978-01-30 | 1981-03-03 | Merrell Toraude Et Compagnie | Process for preparing 4-aminohex-5-ynoic acid |
US4178463A (en) * | 1978-01-30 | 1979-12-11 | Merrell Toraude Et Compagnie | Process for making 4-aminohex-5-enoic acid |
US5147868A (en) * | 1978-07-24 | 1992-09-15 | Merck & Co., Inc. | Thienamycin renal peptidase inhibitors |
US4880793A (en) * | 1978-07-24 | 1989-11-14 | Merck & Co., Inc. | Combination of thienamycin-type antibiotics with dipeptidase inhibitors |
US4323704A (en) * | 1979-06-25 | 1982-04-06 | Merrell Toraude Et Compagnie | αAcetylene and α-vinyl derivatives of amino acids |
US4539208A (en) * | 1980-09-17 | 1985-09-03 | Merck & Co., Inc. | Combination of thienamycin-type antibiotics with dipeptidase inhibitors |
US4372974A (en) * | 1980-06-25 | 1983-02-08 | New York University | Anticonvulsive compositions and method of treating convulsive disorders |
GB2120244B (en) * | 1982-05-17 | 1985-05-01 | Merrell Toraude & Co | Aminoalkadiene derivative |
GB2133002B (en) * | 1982-12-30 | 1986-01-29 | Merrell Toraude & Co | Process for preparing 4-amino-5-hexenoic acid |
GB8311804D0 (en) * | 1983-04-29 | 1983-06-02 | Merrell Toraude & Co | Treatment of seizure disorders and pharmaceutical compositions |
ATE31407T1 (de) * | 1983-07-07 | 1988-01-15 | Syntex Inc | Gamma-allenyl-gamma-aminobuttersaeuren. |
US4668703A (en) * | 1983-07-07 | 1987-05-26 | Syntex (U.S.A.) Inc. | γ-allenyl-γ-aminobutyric acids |
US4661510A (en) * | 1983-08-17 | 1987-04-28 | Syntex (U.S.A.) Inc. | α-allenic-α-amino acids as enzyme inhibitors |
US4588825A (en) * | 1983-10-11 | 1986-05-13 | Merrell Dow Pharmaceuticals Inc. | Intermediates for the synthesis of 4-amino-4,5-dihydro-2-furancarboxylic acid |
US4632994A (en) * | 1983-11-04 | 1986-12-30 | Gruppo Lepetit S.P.A. | Process for decomposing N-oxide derivatives producing 5-vinyl-2-pyrrolidones |
JPS6137389U (ja) * | 1984-08-09 | 1986-03-08 | 永大産業株式会社 | 家具用の戸 |
DE3536146A1 (de) * | 1985-10-10 | 1987-04-16 | Degussa | Verfahren zur enantioselektiven herstellung von (alpha)-vinyl-(alpha)-aminocarbonsaeuren |
US4806680A (en) * | 1986-03-17 | 1989-02-21 | Merck & Co., Inc. | 3-halovinylglycine antibacterial agents |
US4727062A (en) * | 1986-03-17 | 1988-02-23 | Merck & Co., Inc. | 3-Halovinylglycine antibacterial agents |
CA2028782C (fr) | 1989-11-07 | 2003-10-14 | Christian T. Goralski | Methode de production de vinyle-gaba |
IL100360A (en) * | 1990-12-17 | 1998-08-16 | Merrell Dow Pharma | HISTORY OF PYROLIDINONE USED AS SUBSTANCE (S) -Vinyl and Alanyl GABA |
US5208345A (en) * | 1990-12-17 | 1993-05-04 | Merrell Dow Pharmaceuticals Inc. | Process for the production of (S)-vinyl and allenyl gaba |
EP0546230A1 (fr) * | 1991-12-10 | 1993-06-16 | Merrell Dow Pharmaceuticals Inc. | Nouveau procédé pour la préparation de l'acide 4-amino 5-hexénoique |
US5705660A (en) * | 1994-08-22 | 1998-01-06 | Board Of Regents, University Of Nebraska-Lincoln | Method for the synthesis of α-oxiranyl amino acids |
US7098206B2 (en) * | 1998-01-21 | 2006-08-29 | Smithkline Beecham Corporation | Pharmaceutically active morpholinol |
US6998400B2 (en) * | 1998-01-22 | 2006-02-14 | Smithkline Beecham Corporation | Pharmaceutically active morpholinol |
US6458374B1 (en) | 1998-01-29 | 2002-10-01 | Sepracor, Inc. | Methods and compositions for treating chronic disorders using optically pure (+)-bupropion |
CA2318920A1 (fr) * | 1998-01-29 | 1999-08-05 | James W. Young | Utilisations pharmaceutiques de (-)-bupropion optiquement pur |
US6541520B1 (en) | 1998-08-05 | 2003-04-01 | Brookhaven Science Associates | Treatment of addiction and addiction-related behavior |
US6734213B2 (en) | 1999-01-20 | 2004-05-11 | Smithkline Beecham Corporation | Pharmaceutically active morpholinol |
US6855820B2 (en) | 1999-01-20 | 2005-02-15 | Smithkline Beecham Corporation | Pharmaceutically active morpholinol |
US6342496B1 (en) * | 1999-03-01 | 2002-01-29 | Sepracor Inc. | Bupropion metabolites and methods of use |
US6337328B1 (en) * | 1999-03-01 | 2002-01-08 | Sepracor, Inc. | Bupropion metabolites and methods of use |
PL365378A1 (en) | 2000-11-30 | 2005-01-10 | Pfizer Products Inc. | Combination of gaba agonists and aldose reductase inhibitors |
PT1337271E (pt) | 2000-11-30 | 2005-01-31 | Pfizer Prod Inc | Combinacao de agonistas de gaba e inibidores de sorbitol desidrogenase |
MXPA05012317A (es) * | 2003-05-16 | 2006-01-30 | Pfizer Prod Inc | Combinaciones terapeuticas de agentes antipsicoticos atipicos con agentes moduladores del gaba anticonvulsivos o benzodiazepinas. |
EP1691811B1 (fr) | 2003-12-11 | 2014-07-23 | Sunovion Pharmaceuticals Inc. | Combinaison d'un sedatif et d'un modulateur des neurotransmetteurs, et methodes permettant d'ameliorer la qualite du sommeil et de traiter la depression |
JP2007537151A (ja) * | 2004-01-29 | 2007-12-20 | ファイザー・プロダクツ・インク | γ−アミノ酪酸モジュレータと5−HT1B受容体アンタゴニストとの組合せ |
EP2258359A3 (fr) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenèse par modulation des récepteurs muscariniques avec sabcomeline |
JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス,インコーポレイティド | ムスカリン性受容体調節による神経発生 |
AU2006304787A1 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
CA2625210A1 (fr) * | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Modulation de la neurogenese dont la mediation est assuree par recepteur gaba |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
US7678808B2 (en) | 2006-05-09 | 2010-03-16 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
AU2007249399A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
EP2068872A1 (fr) | 2006-09-08 | 2009-06-17 | Braincells, Inc. | Combinaisons contenant un dérivé de 4-acylaminopyridine |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
JP2010521453A (ja) * | 2007-03-15 | 2010-06-24 | サン・ファーマ・アドバンスド・リサーチ・カンパニー・リミテッド | 新規プロドラッグ |
WO2010099217A1 (fr) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation de neurogenèse à l'aide de combinaisons de d-cyclosérine |
EP2537827B1 (fr) | 2011-06-24 | 2014-06-11 | Targeon SAS | Procédé pour la préparation d'acide 4-amino-5-hexénoïque du succinimide |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2460708A (en) * | 1946-03-22 | 1949-02-01 | Merck & Co Inc | Process for making acetamido dimethylacrylic acid |
US2531595A (en) * | 1949-06-09 | 1950-11-28 | Sterling Drug Inc | Preparation of alpha-acylamino-alpha-substituted-acetic acids |
US2588969A (en) * | 1949-11-26 | 1952-03-11 | Eastman Kodak Co | Certain acylamino-acrylates and-crotonates as insecticides |
US3223729A (en) * | 1962-06-06 | 1965-12-14 | Sterling Drug Inc | 3-allylhydantoic acid |
-
1975
- 1975-03-18 US US05/559,544 patent/US3960927A/en not_active Expired - Lifetime
-
1976
- 1976-01-23 IE IE136/76A patent/IE42410B1/en unknown
- 1976-01-26 NZ NZ179834A patent/NZ179834A/en unknown
- 1976-01-26 NO NO760234A patent/NO146428C/no unknown
- 1976-01-26 ZA ZA411A patent/ZA76411B/xx unknown
- 1976-01-26 GB GB285676A patent/GB1472525A/en not_active Expired
- 1976-01-27 IL IL48912A patent/IL48912A/xx unknown
- 1976-01-27 DK DK31476A patent/DK145339C/da not_active IP Right Cessation
- 1976-02-02 PT PT64761A patent/PT64761B/pt unknown
- 1976-02-03 PH PH18044A patent/PH12100A/en unknown
- 1976-02-04 SE SE7601205A patent/SE442295B/xx not_active IP Right Cessation
- 1976-02-04 NL NLAANVRAGE7601116,A patent/NL187161C/xx active Protection Beyond IP Right Term
- 1976-02-17 CA CA245,927A patent/CA1077487A/fr not_active Expired
- 1976-02-25 DE DE2607620A patent/DE2607620C2/de not_active Expired
- 1976-02-26 JP JP51019522A patent/JPS593988B2/ja not_active Expired
- 1976-02-27 CH CH245476A patent/CH631696A5/de active Protection Beyond IP Right Term
- 1976-02-28 ES ES445659A patent/ES445659A1/es not_active Expired
- 1976-03-02 MX MX7665U patent/MX4654E/es unknown
- 1976-03-16 FR FR7607547A patent/FR2304329A1/fr active Granted
- 1976-03-17 BE BE165245A patent/BE839657A/fr not_active IP Right Cessation
-
1993
- 1993-06-30 NL NL930125C patent/NL930125I2/nl unknown
Also Published As
Publication number | Publication date |
---|---|
AU1071676A (en) | 1977-08-11 |
PH12100A (en) | 1978-11-02 |
ES445659A1 (es) | 1977-06-01 |
MX4654E (es) | 1982-07-19 |
IL48912A (en) | 1980-09-16 |
NO146428B (no) | 1982-06-21 |
IE42410B1 (en) | 1980-07-30 |
DK145339B (da) | 1982-11-01 |
NL187161C (nl) | 1991-06-17 |
ZA76411B (en) | 1977-01-26 |
CA1077487A (fr) | 1980-05-13 |
NL930125I1 (nl) | 1993-11-01 |
DE2607620A1 (de) | 1976-09-30 |
SE7601205L (sv) | 1976-09-19 |
DK145339C (da) | 1983-03-21 |
IL48912A0 (en) | 1976-03-31 |
DE2607620C2 (de) | 1984-09-13 |
IE42410L (en) | 1976-09-18 |
US3960927A (en) | 1976-06-01 |
PT64761A (en) | 1976-03-01 |
DK31476A (da) | 1976-09-19 |
SE442295B (sv) | 1985-12-16 |
BE839657A (fr) | 1976-07-16 |
GB1472525A (en) | 1977-05-04 |
CH631696A5 (de) | 1982-08-31 |
FR2304329B1 (fr) | 1980-07-18 |
NZ179834A (en) | 1978-06-20 |
NL7601116A (nl) | 1976-09-21 |
NL930125I2 (nl) | 1997-08-01 |
JPS51125320A (en) | 1976-11-01 |
PT64761B (en) | 1977-06-06 |
NL187161B (nl) | 1991-01-16 |
NO146428C (no) | 1982-09-29 |
JPS593988B2 (ja) | 1984-01-27 |
NO760234L (fr) | 1976-09-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TP | Transmission of property | ||
CC | Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990) |
Free format text: 92C0320, 920526 |
|
CB | Supplementary protection certificate (spc) granted (law of 25 june 1990) |
Free format text: 92C0320, 760316 |
|
CL | Concession to grant licences | ||
TP | Transmission of property |