NO146428C - Analogifremgangsmaate ved fremstilling av terapeutisk aktive olefiniske derivater av aminosyrer - Google Patents

Analogifremgangsmaate ved fremstilling av terapeutisk aktive olefiniske derivater av aminosyrer

Info

Publication number
NO146428C
NO146428C NO760234A NO760234A NO146428C NO 146428 C NO146428 C NO 146428C NO 760234 A NO760234 A NO 760234A NO 760234 A NO760234 A NO 760234A NO 146428 C NO146428 C NO 146428C
Authority
NO
Norway
Prior art keywords
preparation
amino acids
therapeutic active
analogy procedure
active olefinic
Prior art date
Application number
NO760234A
Other languages
English (en)
Other versions
NO760234L (no
NO146428B (no
Inventor
Brian Walter Metcalf
Michel Jung
Original Assignee
Merrell Toraude & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Toraude & Co filed Critical Merrell Toraude & Co
Publication of NO760234L publication Critical patent/NO760234L/no
Publication of NO146428B publication Critical patent/NO146428B/no
Publication of NO146428C publication Critical patent/NO146428C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO760234A 1975-03-18 1976-01-26 Analogifremgangsmaate ved fremstilling av terapeutisk aktive olefiniske derivater av aminosyrer NO146428C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/559,544 US3960927A (en) 1975-03-18 1975-03-18 Olefinic derivatives of amino acids

Publications (3)

Publication Number Publication Date
NO760234L NO760234L (no) 1976-09-21
NO146428B NO146428B (no) 1982-06-21
NO146428C true NO146428C (no) 1982-09-29

Family

ID=24233995

Family Applications (1)

Application Number Title Priority Date Filing Date
NO760234A NO146428C (no) 1975-03-18 1976-01-26 Analogifremgangsmaate ved fremstilling av terapeutisk aktive olefiniske derivater av aminosyrer

Country Status (20)

Country Link
US (1) US3960927A (no)
JP (1) JPS593988B2 (no)
BE (1) BE839657A (no)
CA (1) CA1077487A (no)
CH (1) CH631696A5 (no)
DE (1) DE2607620C2 (no)
DK (1) DK145339C (no)
ES (1) ES445659A1 (no)
FR (1) FR2304329A1 (no)
GB (1) GB1472525A (no)
IE (1) IE42410B1 (no)
IL (1) IL48912A (no)
MX (1) MX4654E (no)
NL (2) NL187161C (no)
NO (1) NO146428C (no)
NZ (1) NZ179834A (no)
PH (1) PH12100A (no)
PT (1) PT64761B (no)
SE (1) SE442295B (no)
ZA (1) ZA76411B (no)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4039549A (en) * 1975-03-18 1977-08-02 Merrell Toraude Et Compagnie Olefinic derivatives of amino acids
US4041041A (en) * 1975-03-18 1977-08-09 Merrell Toraude Et Compagnie Acetylene derivatives of amino acids
CA1157030A (en) * 1977-07-01 1983-11-15 Brian W. Metcalf .alpha.-VINYL AMINO ACIDS
US4147873A (en) * 1977-07-01 1979-04-03 Merrell Toraude Et Compagnie α-Vinyl derivatives of α-amino acids
US4139563A (en) * 1977-07-01 1979-02-13 Merrell Toraude Et Compagnie α-ACETYLENIC DERIVATIVES OF AMINES
CA1121375A (en) * 1977-07-01 1982-04-06 Brian W. Metcalf Derivatives of amines and amino acids
US4326071A (en) * 1977-09-28 1982-04-20 Merrell Toraude Et Compagnie Halomethyl derivatives of gamma-aminobutyric acid and related compounds
US4187316A (en) * 1978-01-12 1980-02-05 Merrell Toraude Et Compagnie Substituted 1,5-cyclohexadiene carboxylic acid derivatives
US4254284A (en) * 1978-01-30 1981-03-03 Merrell Toraude Et Compagnie Process for preparing 4-aminohex-5-ynoic acid
US4178463A (en) * 1978-01-30 1979-12-11 Merrell Toraude Et Compagnie Process for making 4-aminohex-5-enoic acid
US5147868A (en) * 1978-07-24 1992-09-15 Merck & Co., Inc. Thienamycin renal peptidase inhibitors
US4880793A (en) * 1978-07-24 1989-11-14 Merck & Co., Inc. Combination of thienamycin-type antibiotics with dipeptidase inhibitors
US4323704A (en) * 1979-06-25 1982-04-06 Merrell Toraude Et Compagnie αAcetylene and α-vinyl derivatives of amino acids
US4539208A (en) * 1980-09-17 1985-09-03 Merck & Co., Inc. Combination of thienamycin-type antibiotics with dipeptidase inhibitors
US4372974A (en) * 1980-06-25 1983-02-08 New York University Anticonvulsive compositions and method of treating convulsive disorders
GB2120244B (en) * 1982-05-17 1985-05-01 Merrell Toraude & Co Aminoalkadiene derivative
GB2133002B (en) * 1982-12-30 1986-01-29 Merrell Toraude & Co Process for preparing 4-amino-5-hexenoic acid
GB8311804D0 (en) * 1983-04-29 1983-06-02 Merrell Toraude & Co Treatment of seizure disorders and pharmaceutical compositions
US4668703A (en) * 1983-07-07 1987-05-26 Syntex (U.S.A.) Inc. γ-allenyl-γ-aminobutyric acids
NO842759L (no) * 1983-07-07 1985-01-08 Syntex Inc Fremgangsmaate ved fremstilling av nye, terapeutisk virksomme gamma-allenyl-gamma-aminosmoersyrer
US4661510A (en) * 1983-08-17 1987-04-28 Syntex (U.S.A.) Inc. α-allenic-α-amino acids as enzyme inhibitors
US4588825A (en) * 1983-10-11 1986-05-13 Merrell Dow Pharmaceuticals Inc. Intermediates for the synthesis of 4-amino-4,5-dihydro-2-furancarboxylic acid
US4632994A (en) * 1983-11-04 1986-12-30 Gruppo Lepetit S.P.A. Process for decomposing N-oxide derivatives producing 5-vinyl-2-pyrrolidones
JPS6137389U (ja) * 1984-08-09 1986-03-08 永大産業株式会社 家具用の戸
DE3536146A1 (de) * 1985-10-10 1987-04-16 Degussa Verfahren zur enantioselektiven herstellung von (alpha)-vinyl-(alpha)-aminocarbonsaeuren
US4727062A (en) * 1986-03-17 1988-02-23 Merck & Co., Inc. 3-Halovinylglycine antibacterial agents
US4806680A (en) * 1986-03-17 1989-02-21 Merck & Co., Inc. 3-halovinylglycine antibacterial agents
CA2028782C (en) * 1989-11-07 2003-10-14 Christian T. Goralski Process for the production of vinyl-gaba
AU644919B2 (en) * 1990-12-17 1993-12-23 Aventisub Ii Inc. Process for the production of (S)-vinyl and allenyl gaba
US5208345A (en) * 1990-12-17 1993-05-04 Merrell Dow Pharmaceuticals Inc. Process for the production of (S)-vinyl and allenyl gaba
EP0546230A1 (en) * 1991-12-10 1993-06-16 Merrell Dow Pharmaceuticals Inc. Novel process for preparing 4-amino-5-hexenoic acid
US5705660A (en) * 1994-08-22 1998-01-06 Board Of Regents, University Of Nebraska-Lincoln Method for the synthesis of α-oxiranyl amino acids
US7098206B2 (en) * 1998-01-21 2006-08-29 Smithkline Beecham Corporation Pharmaceutically active morpholinol
US6998400B2 (en) * 1998-01-22 2006-02-14 Smithkline Beecham Corporation Pharmaceutically active morpholinol
US6458374B1 (en) 1998-01-29 2002-10-01 Sepracor, Inc. Methods and compositions for treating chronic disorders using optically pure (+)-bupropion
WO1999038504A1 (en) * 1998-01-29 1999-08-05 Sepracor Inc. Pharmaceutical uses of optically pure (-)-bupropion
US6541520B1 (en) 1998-08-05 2003-04-01 Brookhaven Science Associates Treatment of addiction and addiction-related behavior
US6734213B2 (en) 1999-01-20 2004-05-11 Smithkline Beecham Corporation Pharmaceutically active morpholinol
US6855820B2 (en) * 1999-01-20 2005-02-15 Smithkline Beecham Corporation Pharmaceutically active morpholinol
US6342496B1 (en) * 1999-03-01 2002-01-29 Sepracor Inc. Bupropion metabolites and methods of use
US6337328B1 (en) * 1999-03-01 2002-01-08 Sepracor, Inc. Bupropion metabolites and methods of use
CA2430298A1 (en) 2000-11-30 2002-06-06 Banavara Lakshman Mylari Combination of gaba agonists and sorbitol dehydrogenase inhibitors
HUP0302555A3 (en) 2000-11-30 2005-06-28 Pfizer Prod Inc Pharmaceutical compositions containing gaba agonists and aldose reductase inhibitors
AU2004237951A1 (en) * 2003-05-16 2004-11-25 Pfizer Products Inc. Therapeutic combinations of atypical antipsychotics with GABA modulators, anticonvulsants or benzodiazapines
WO2005060968A1 (en) 2003-12-11 2005-07-07 Sepracor Inc. Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
JP2007537151A (ja) * 2004-01-29 2007-12-20 ファイザー・プロダクツ・インク γ−アミノ酪酸モジュレータと５−ＨＴ１Ｂ受容体アンタゴニストとの組合せ
CA2620333A1 (en) 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
EP2377530A3 (en) 2005-10-21 2012-06-20 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
WO2007053596A1 (en) * 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2026813A2 (en) 2006-05-09 2009-02-25 Braincells, Inc. 5 ht receptor mediated neurogenesis
JP2009536669A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド アンジオテンシン調節による神経新生
KR20090064418A (ko) 2006-09-08 2009-06-18 브레인셀즈 인코퍼레이션 4-아실아미노피리딘 유도체 포함 조합물
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
CA2679741A1 (en) * 2007-03-15 2008-09-18 Sun Pharma Advanced Research Company Ltd. Novel prodrugs
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
EP2537827B1 (en) 2011-06-24 2014-06-11 Targeon SAS Process for preparing 4-amino-5-hexenoic acid from succinimide

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2460708A (en) * 1946-03-22 1949-02-01 Merck & Co Inc Process for making acetamido dimethylacrylic acid
US2531595A (en) * 1949-06-09 1950-11-28 Sterling Drug Inc Preparation of alpha-acylamino-alpha-substituted-acetic acids
US2588969A (en) * 1949-11-26 1952-03-11 Eastman Kodak Co Certain acylamino-acrylates and-crotonates as insecticides
US3223729A (en) * 1962-06-06 1965-12-14 Sterling Drug Inc 3-allylhydantoic acid

Also Published As

Publication number Publication date
BE839657A (fr) 1976-07-16
ES445659A1 (es) 1977-06-01
NL187161B (nl) 1991-01-16
JPS51125320A (en) 1976-11-01
IL48912A0 (en) 1976-03-31
NO760234L (no) 1976-09-21
SE442295B (sv) 1985-12-16
NL930125I1 (nl) 1993-11-01
CA1077487A (en) 1980-05-13
FR2304329A1 (fr) 1976-10-15
DK31476A (da) 1976-09-19
NL187161C (nl) 1991-06-17
MX4654E (es) 1982-07-19
SE7601205L (sv) 1976-09-19
US3960927A (en) 1976-06-01
JPS593988B2 (ja) 1984-01-27
PH12100A (en) 1978-11-02
CH631696A5 (de) 1982-08-31
NL7601116A (nl) 1976-09-21
DE2607620A1 (de) 1976-09-30
DE2607620C2 (de) 1984-09-13
PT64761A (en) 1976-03-01
AU1071676A (en) 1977-08-11
NZ179834A (en) 1978-06-20
IL48912A (en) 1980-09-16
FR2304329B1 (no) 1980-07-18
GB1472525A (en) 1977-05-04
NO146428B (no) 1982-06-21
NL930125I2 (nl) 1997-08-01
DK145339C (da) 1983-03-21
DK145339B (da) 1982-11-01
IE42410L (en) 1976-09-18
IE42410B1 (en) 1980-07-30
PT64761B (en) 1977-06-06
ZA76411B (en) 1977-01-26

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