FI63233C - Foerfarande foer framstaellning av ulcushaemmande 5,11-dihydro-6h-pyrido-(2,3-b)(1,4)benzodiazepin-6-on-derivat - Google Patents

Foerfarande foer framstaellning av ulcushaemmande 5,11-dihydro-6h-pyrido-(2,3-b)(1,4)benzodiazepin-6-on-derivat Download PDF

Info

Publication number
FI63233C
FI63233C FI781690A FI781690A FI63233C FI 63233 C FI63233 C FI 63233C FI 781690 A FI781690 A FI 781690A FI 781690 A FI781690 A FI 781690A FI 63233 C FI63233 C FI 63233C
Authority
FI
Finland
Prior art keywords
methylamino
methyl
pyrrolidin
group
pyrido
Prior art date
Application number
FI781690A
Other languages
English (en)
Finnish (fi)
Other versions
FI781690A (fi
FI63233B (fi
Inventor
Guenther Schmidt
Matyas Leitold
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2724478A external-priority patent/DE2724478C2/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of FI781690A publication Critical patent/FI781690A/fi
Application granted granted Critical
Publication of FI63233B publication Critical patent/FI63233B/fi
Publication of FI63233C publication Critical patent/FI63233C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI781690A 1977-05-31 1978-05-26 Foerfarande foer framstaellning av ulcushaemmande 5,11-dihydro-6h-pyrido-(2,3-b)(1,4)benzodiazepin-6-on-derivat FI63233C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2724478 1977-05-31
DE2724478A DE2724478C2 (de) 1977-05-31 1977-05-31 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (3)

Publication Number Publication Date
FI781690A FI781690A (fi) 1978-12-01
FI63233B FI63233B (fi) 1983-01-31
FI63233C true FI63233C (fi) 1983-05-10

Family

ID=6010286

Family Applications (1)

Application Number Title Priority Date Filing Date
FI781690A FI63233C (fi) 1977-05-31 1978-05-26 Foerfarande foer framstaellning av ulcushaemmande 5,11-dihydro-6h-pyrido-(2,3-b)(1,4)benzodiazepin-6-on-derivat

Country Status (30)

Country Link
US (1) US4210648A (xx)
JP (1) JPS543092A (xx)
AT (1) AT361929B (xx)
AU (1) AU516712B2 (xx)
BE (1) BE867639A (xx)
BG (1) BG28712A3 (xx)
CA (1) CA1081220A (xx)
CH (1) CH637956A5 (xx)
CS (1) CS202600B2 (xx)
DD (1) DD135490A5 (xx)
DK (1) DK148233C (xx)
ES (1) ES470269A1 (xx)
FI (1) FI63233C (xx)
FR (1) FR2392991A1 (xx)
GB (1) GB1581500A (xx)
GR (1) GR64535B (xx)
HK (1) HK19381A (xx)
HU (1) HU180540B (xx)
IE (1) IE46909B1 (xx)
IL (1) IL54815A (xx)
MY (1) MY8100362A (xx)
NL (1) NL7805848A (xx)
NO (1) NO149065C (xx)
NZ (1) NZ187428A (xx)
PL (1) PL113999B1 (xx)
PT (1) PT68114A (xx)
SE (1) SE437831B (xx)
SU (1) SU797578A3 (xx)
YU (1) YU129478A (xx)
ZA (1) ZA783086B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2053187A (en) * 1979-07-09 1981-02-04 Grissmann Chem Ltd Process for preparing pyrenzepine
GR72993B (xx) * 1980-01-24 1984-01-25 Crc Ricerca Chim
IT1130973B (it) * 1980-03-17 1986-06-18 Microsules Argentina Sa De S C Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one,derivati finali ed intermedi di sintesi in tal modo ottenuti
DE3212794A1 (de) * 1982-04-06 1983-10-13 Basf Ag, 6700 Ludwigshafen 5,6-dihydro-11-alkylen-morphantridin-6-one, ihre herstellung und diese enthaltende arzneimittel
IT1212743B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Sali quaternari di derivati di benzo[ 1,4 ]diazepinonici,pirido [1,4]benzodiazepinonici,prido [1,5]benzodiazepinonici e loro atti vita' farmacologica
IT1212742B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Derivati dibenzo [1,4]diazepinonici pirido [1,4] benzodiazepinonici,pirido [1,5] benzodiazepinonici e loro attivita' farmacologica
DE3626095A1 (de) * 1986-07-31 1988-02-11 Thomae Gmbh Dr K Neue substituierte pyrido(2,3-b)(1,4)benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3643666A1 (de) * 1986-12-20 1988-06-30 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3802334A1 (de) * 1988-01-27 1989-08-10 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820347A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Verwendung von in 11-stellung substituierten 5,11-dihydro-6h-pyrido(2,3-b) (1,4)benzodiazepin-6-onen zur behandlung von bradycardien und bradyarrhythmien in der human- und veterinaermedizin
DE3820346A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5264432A (en) * 1989-07-31 1993-11-23 Arzneimittelwerk Dresden G.M.B.H 5-(1-aminoacyl)-5,10-dihydro-11H-dibenzo[b,e](1,4)diazepin-11-ones
DE3930262A1 (de) * 1989-09-11 1991-03-21 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3930266A1 (de) * 1989-09-11 1991-03-14 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5418229A (en) * 1990-01-06 1995-05-23 Alker; David Muscarinic receptor antagonists
GB9000302D0 (en) * 1990-01-06 1990-03-07 Pfizer Ltd Muscarinic receptor antagonists
US8466144B2 (en) 2004-07-16 2013-06-18 Proteosys Ag Muscarinic antagonists with parp and sir modulating activity as cytoprotective agents
EP2387405A2 (en) 2009-01-13 2011-11-23 ProteoSys AG Pirenzepine as an agent in cancer treatment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795183B1 (de) * 1968-08-20 1972-07-20 Thomae Gmbh Dr K 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel
US3691152A (en) * 1971-03-10 1972-09-12 Texaco Inc Hydrodesulfurization and blending of residue-containing petroleum oil

Also Published As

Publication number Publication date
IL54815A (en) 1981-07-31
JPS543092A (en) 1979-01-11
DK148233B (da) 1985-05-13
FR2392991B1 (xx) 1982-10-22
ZA783086B (en) 1980-02-27
SE437831B (sv) 1985-03-18
HU180540B (en) 1983-03-28
CA1081220A (en) 1980-07-08
GB1581500A (en) 1980-12-17
GR64535B (en) 1980-04-10
IE781073L (en) 1978-11-30
FI781690A (fi) 1978-12-01
CH637956A5 (de) 1983-08-31
NO149065B (no) 1983-10-31
JPS6216952B2 (xx) 1987-04-15
US4210648A (en) 1980-07-01
NO781880L (no) 1978-12-01
FR2392991A1 (fr) 1978-12-29
DD135490A5 (de) 1979-05-09
ATA367778A (de) 1980-09-15
MY8100362A (en) 1981-12-31
IE46909B1 (en) 1983-11-02
SU797578A3 (ru) 1981-01-15
ES470269A1 (es) 1979-01-01
SE7806287L (sv) 1978-12-01
AU516712B2 (en) 1981-06-18
AU3662478A (en) 1979-12-06
BG28712A3 (en) 1980-06-16
PL113999B1 (en) 1981-01-31
PT68114A (de) 1978-06-01
BE867639A (fr) 1978-11-30
AT361929B (de) 1981-04-10
NO149065C (no) 1984-02-08
HK19381A (en) 1981-05-15
NL7805848A (nl) 1978-12-04
NZ187428A (en) 1981-01-23
DK148233C (da) 1985-10-21
PL207192A1 (pl) 1979-04-23
FI63233B (fi) 1983-01-31
CS202600B2 (en) 1981-01-30
YU129478A (en) 1983-02-28
DK239378A (da) 1978-12-01

Similar Documents

Publication Publication Date Title
FI63233C (fi) Foerfarande foer framstaellning av ulcushaemmande 5,11-dihydro-6h-pyrido-(2,3-b)(1,4)benzodiazepin-6-on-derivat
DE60307483T2 (de) Organische verbindungen als mittel zur behandlung von aldosteronbedingten zuständen
DE60210067T2 (de) Tricyklische diazepine als tocolytische oxytocinrezeptor-antagonisten
KR920003980B1 (ko) 축합 디아제핀온의 제조방법
US7329653B2 (en) Cyclohexylphenyl vasopressin agonists
WO2002083683A1 (en) Novel tricyclic pyridyl benzazepine carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists
EP1377583A1 (en) Novel tricyclic hydroxy carboxamides and derivatives thereof; tocolytic oxytocin receptor antagonists
US4762832A (en) Morpholine containing pyrrolidinones pharmaceutical compositions and use
US5175158A (en) Condensed diazepinones, processes for preparing them and pharmaceutical compositions containing these compounds
CS207619B2 (en) Method of making the new derivatives of 5,11-dihydro-6h-pyrido 2,3-b 1,4 benzodiazepin-6-on
EP0064317B1 (en) Pyrrolo(2,3-d)carbazole derivatives, preparation thereof and their therapeutical use
US4971966A (en) Substituted pyrido(2,3-B) (1,4) benzodiazepin-6-ones, and medicaments containing these compounds
US4873236A (en) Condensed diazepinones, processes for preparing them and pharmaceutical compositions containing these compounds
EP0338989B1 (en) Heterotetracyclic lactam derivatives, process for their preparation, and pharmaceutical compositions containing them
KR100196969B1 (ko) 축합 디아제피논, 이의 제조방법 및 이를 함유하는 약제학적 조성물
RU2057754C1 (ru) Гетероциклические соединения или их кислотно-аддитивные соли
US4946840A (en) Benzazepine and benzothiazepine derivatives
KR920000763B1 (ko) 신규 벤조디아제핀의 제조 방법
US4931436A (en) Condensed diazepinones, processes for preparing them and pharmaceutical compositions containing these compounds
Farber et al. Reaction of 6-Chloro-2-chloromethyl-4-phenylquinazoline 3-Oxide with Dimethylamine
US3483187A (en) Certain n11-substituted pyridobenzodiazepine derivatives
US4515949A (en) [2-(1H-indol-1-yl)ethyl]-2-piperazine and pyrido[1,2-a]indol-9-one as intermediates for pyrazino(2,3-3,4)pyrido(1,2-a) indoles which are useful for treating hypertension in mammals
EP0743946A1 (en) 5ht2b receptor antagonists condensed indoles
EP1015457A1 (en) 1,3-dioxolo/4,5-h//2,3/benzodiazepine derivatives as ampa/kainate receptor inhibitors
KR810000809B1 (ko) 11-위치 치환 5,11-디하이드로-6H-피리도 [2,3-b][1,4] 벤조디아제핀-6-온의 제조공정

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: DR. KARL THOMAE GESELLSCHAFT MIT