CN1925855B - 开发Ret调节剂的化合物和方法 - Google Patents

开发Ret调节剂的化合物和方法 Download PDF

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CN1925855B
CN1925855B CN2004800419081A CN200480041908A CN1925855B CN 1925855 B CN1925855 B CN 1925855B CN 2004800419081 A CN2004800419081 A CN 2004800419081A CN 200480041908 A CN200480041908 A CN 200480041908A CN 1925855 B CN1925855 B CN 1925855B
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pyrrolo
pyridin
phenyl
ketone
fluoro
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CN1925855A (zh
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P·N·易卜拉欣
D·R·阿尔蒂
R·布雷默
G·哈贝茨
C·R·赫特
S·马莫
M·内斯皮
C·张
J·张
Y·朱
R·扎克马恩
H·克鲁普卡
A·鸠摩
B·维斯特
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Presico
Plexxikon Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Peptides Or Proteins (AREA)
CN2004800419081A 2003-12-19 2004-12-17 开发Ret调节剂的化合物和方法 Active CN1925855B (zh)

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US53128103P 2003-12-19 2003-12-19
US60/531,281 2003-12-19
US55858104P 2004-03-31 2004-03-31
US60/558,581 2004-03-31
PCT/US2004/042470 WO2005062795A2 (en) 2003-12-19 2004-12-17 Compounds and methods for development of ret modulators

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CN1925855A CN1925855A (zh) 2007-03-07
CN1925855B true CN1925855B (zh) 2010-06-16

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CN (1) CN1925855B (US07504509-20090317-C00146.png)
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CA (1) CA2550361C (US07504509-20090317-C00146.png)
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ES (1) ES2527118T3 (US07504509-20090317-C00146.png)
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