CN1898221A - Atp-结合弹夹转运蛋白的调控剂 - Google Patents
Atp-结合弹夹转运蛋白的调控剂 Download PDFInfo
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- CN1898221A CN1898221A CNA200480031503XA CN200480031503A CN1898221A CN 1898221 A CN1898221 A CN 1898221A CN A200480031503X A CNA200480031503X A CN A200480031503XA CN 200480031503 A CN200480031503 A CN 200480031503A CN 1898221 A CN1898221 A CN 1898221A
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- phenyl
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- 0 CC(CCC1N)C=C1C(C1=CC=C(*(C(C(CN)c2ccccc2)=O)=C)[Cn]1)=O Chemical compound CC(CCC1N)C=C1C(C1=CC=C(*(C(C(CN)c2ccccc2)=O)=C)[Cn]1)=O 0.000 description 4
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
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- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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- A61K31/5375—1,4-Oxazines, e.g. morpholine
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- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50044403P | 2003-09-06 | 2003-09-06 | |
| US60/500,444 | 2003-09-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1898221A true CN1898221A (zh) | 2007-01-17 |
Family
ID=34312193
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA200480031503XA Pending CN1898221A (zh) | 2003-09-06 | 2004-09-07 | Atp-结合弹夹转运蛋白的调控剂 |
Country Status (13)
| Country | Link |
|---|---|
| US (6) | US7973169B2 (enExample) |
| EP (1) | EP1664006A2 (enExample) |
| JP (1) | JP2007504255A (enExample) |
| KR (1) | KR20060088537A (enExample) |
| CN (1) | CN1898221A (enExample) |
| AU (1) | AU2004272599A1 (enExample) |
| CA (1) | CA2537841A1 (enExample) |
| IL (1) | IL174128A0 (enExample) |
| MX (1) | MXPA06002567A (enExample) |
| NO (1) | NO20061543L (enExample) |
| RU (1) | RU2006111093A (enExample) |
| WO (1) | WO2005026137A2 (enExample) |
| ZA (1) | ZA200602755B (enExample) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103889965A (zh) * | 2011-09-23 | 2014-06-25 | 拜尔斯道夫股份公司 | 杂环羰基氨基噻唑、包含其的化妆或皮肤学制剂及其用于克服和预防不期望的皮肤色素沉着的用途 |
| CN105693701A (zh) * | 2008-11-06 | 2016-06-22 | 弗特克斯药品有限公司 | Atp-结合盒转运蛋白的调节剂 |
| US10058546B2 (en) | 2012-07-16 | 2018-08-28 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions of (R)-1-(2,2-difluorobenzo[D][1,3]dioxo1-5-y1)-N-(1-(2,3-dihydroxypropy1)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-y1)-1H-indol-5-y1) cyclopropanecarbox-amide and administration thereof |
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-
2004
- 2004-09-07 US US10/936,448 patent/US7973169B2/en active Active
- 2004-09-07 ZA ZA200602755A patent/ZA200602755B/en unknown
- 2004-09-07 EP EP04783449A patent/EP1664006A2/en not_active Withdrawn
- 2004-09-07 AU AU2004272599A patent/AU2004272599A1/en not_active Abandoned
- 2004-09-07 JP JP2006525534A patent/JP2007504255A/ja active Pending
- 2004-09-07 KR KR1020067004627A patent/KR20060088537A/ko not_active Withdrawn
- 2004-09-07 MX MXPA06002567A patent/MXPA06002567A/es unknown
- 2004-09-07 RU RU2006111093/04A patent/RU2006111093A/ru not_active Application Discontinuation
- 2004-09-07 CN CNA200480031503XA patent/CN1898221A/zh active Pending
- 2004-09-07 CA CA002537841A patent/CA2537841A1/en not_active Abandoned
- 2004-09-07 WO PCT/US2004/029206 patent/WO2005026137A2/en not_active Ceased
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2006
- 2006-03-06 IL IL174128A patent/IL174128A0/en unknown
- 2006-04-05 NO NO20061543A patent/NO20061543L/no not_active Application Discontinuation
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2011
- 2011-07-01 US US13/174,844 patent/US8431605B2/en not_active Expired - Fee Related
-
2013
- 2013-03-22 US US13/848,970 patent/US8741939B2/en not_active Expired - Fee Related
- 2013-11-14 US US14/079,664 patent/US8853415B2/en not_active Expired - Fee Related
-
2014
- 2014-10-06 US US14/506,856 patent/US9249131B2/en not_active Expired - Lifetime
-
2016
- 2016-01-29 US US15/010,542 patent/US20160228414A1/en not_active Abandoned
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| USRE50453E1 (en) | 2006-04-07 | 2025-06-10 | Vertex Pharmaceuticals Incorporated | Indole derivatives as CFTR modulators |
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| US10980746B2 (en) | 2014-04-15 | 2021-04-20 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases |
| CN110099684B (zh) * | 2016-11-03 | 2022-11-11 | 科尔沃斯制药股份有限公司 | 用于调节白介素-2诱导性t细胞激酶的化合物和方法 |
| CN110099684A (zh) * | 2016-11-03 | 2019-08-06 | 科尔沃斯制药股份有限公司 | 用于调节白介素-2诱导性t细胞激酶的化合物和方法 |
| CN116621794A (zh) * | 2023-05-22 | 2023-08-22 | 上海大学 | 一种5-苄基-2-氨基-1,3-噻唑类衍生物及其合成方法与应用 |
| CN116621794B (zh) * | 2023-05-22 | 2025-03-11 | 上海大学 | 一种5-苄基-2-氨基-1,3-噻唑类衍生物及其合成方法与应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA06002567A (es) | 2006-09-04 |
| WO2005026137A3 (en) | 2005-07-21 |
| US20130252333A1 (en) | 2013-09-26 |
| US8741939B2 (en) | 2014-06-03 |
| EP1664006A2 (en) | 2006-06-07 |
| US20050176789A1 (en) | 2005-08-11 |
| RU2006111093A (ru) | 2007-10-27 |
| US9249131B2 (en) | 2016-02-02 |
| CA2537841A1 (en) | 2005-03-24 |
| NO20061543L (no) | 2006-06-06 |
| US7973169B2 (en) | 2011-07-05 |
| US20140072995A1 (en) | 2014-03-13 |
| US8853415B2 (en) | 2014-10-07 |
| KR20060088537A (ko) | 2006-08-04 |
| JP2007504255A (ja) | 2007-03-01 |
| US20150025076A1 (en) | 2015-01-22 |
| WO2005026137A2 (en) | 2005-03-24 |
| ZA200602755B (en) | 2007-06-27 |
| IL174128A0 (en) | 2006-08-01 |
| US8431605B2 (en) | 2013-04-30 |
| AU2004272599A1 (en) | 2005-03-24 |
| US20160228414A1 (en) | 2016-08-11 |
| US20120004216A1 (en) | 2012-01-05 |
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