CN1878793A - 拮抗hmgb1的单克隆抗体 - Google Patents
拮抗hmgb1的单克隆抗体 Download PDFInfo
- Publication number
- CN1878793A CN1878793A CNA2004800332177A CN200480033217A CN1878793A CN 1878793 A CN1878793 A CN 1878793A CN A2004800332177 A CNA2004800332177 A CN A2004800332177A CN 200480033217 A CN200480033217 A CN 200480033217A CN 1878793 A CN1878793 A CN 1878793A
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- Prior art keywords
- antibody
- antigen
- binding fragment
- hmgb1
- hmgb1 mab
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4718—Cytokine-induced proteins
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- C07K—PEPTIDES
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- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Zoology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50256803P | 2003-09-11 | 2003-09-11 | |
| US60/502,568 | 2003-09-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1878793A true CN1878793A (zh) | 2006-12-13 |
Family
ID=34312406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2004800332177A Pending CN1878793A (zh) | 2003-09-11 | 2004-09-10 | 拮抗hmgb1的单克隆抗体 |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US7288250B2 (https=) |
| EP (1) | EP1668035A2 (https=) |
| JP (2) | JP4792392B2 (https=) |
| CN (1) | CN1878793A (https=) |
| AU (1) | AU2004272607B2 (https=) |
| CA (2) | CA2882022A1 (https=) |
| WO (1) | WO2005026209A2 (https=) |
Cited By (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101798347A (zh) * | 2009-03-03 | 2010-08-11 | 中国科学院生物物理研究所 | 抗高迁移率族蛋白b1的单克隆抗体 |
| CN101891817A (zh) * | 2009-03-03 | 2010-11-24 | 中国科学院生物物理研究所 | 抗高迁移率族蛋白b-1的单克隆抗体及其应用 |
| CN102375064A (zh) * | 2010-08-26 | 2012-03-14 | 杭州华得森生物技术有限公司 | 用酶联免疫法检测人体中hmga2含量的体外诊断试剂盒 |
| CN102625836A (zh) * | 2009-07-16 | 2012-08-01 | Nec软件有限公司 | Hmgb1结合核酸分子及其用途 |
| CN102924577A (zh) * | 2012-11-28 | 2013-02-13 | 扬州大学 | 鸡高迁移率族蛋白b1抗原多肽和抗鸡高迁移率族蛋白b1单克隆抗体 |
| CN102209897B (zh) * | 2008-09-11 | 2015-04-29 | 巴斯德研究院 | 通过调节hiv-1复制和顽固存在的hmgb1依赖性触发来监测和抑制人免疫缺陷病毒感染 |
| CN104955846A (zh) * | 2013-01-28 | 2015-09-30 | 株式会社伊贝克 | 人源化抗hmgb1抗体或其抗原结合性片段 |
| TWI609881B (zh) * | 2013-11-04 | 2018-01-01 | 金立德 | 抗高遷移率族蛋白b1(hmgb1)之完全人類抗體、用於製造hmgb1之完全人類抗體之方法、以及製備用於治療或抑制hmgb1相關視神經脊髓炎之藥物之方法 |
| CN108912228A (zh) * | 2009-05-08 | 2018-11-30 | 瓦西尼斯公司 | 抗-cd100抗体和其使用方法 |
| CN109957015A (zh) * | 2019-04-01 | 2019-07-02 | 中国人民解放军海军军医大学国家肝癌科学中心 | 一种hmgb1封闭性抗体的制备方法及其应用 |
| CN113151186A (zh) * | 2021-02-04 | 2021-07-23 | 上海交通大学 | 抗人cd271的单克隆抗体及用途 |
| CN113203857A (zh) * | 2021-05-06 | 2021-08-03 | 北京保图生物技术有限公司 | 一种肿瘤诊断试剂盒 |
| CN114106139A (zh) * | 2011-04-26 | 2022-03-01 | 斯特姆里姆有限公司 | 用于诱导组织再生的肽及其应用 |
| US11534488B2 (en) | 2011-10-11 | 2022-12-27 | Vaccinex, Inc. | Use of semaphorin-4D binding molecules for modulation of blood brain barrier permeability |
| CN115433283B (zh) * | 2017-09-06 | 2024-05-24 | 安斯泰来制药有限公司 | 用于癌症诊断的抗体 |
| CN119775409A (zh) * | 2025-03-05 | 2025-04-08 | 深圳真实生物医药科技有限公司 | 靶向sost的抗体及其用途 |
| CN119775408A (zh) * | 2025-03-12 | 2025-04-08 | 武汉伊莱瑞特生物科技股份有限公司 | 抗猴高迁移率族蛋白b1单克隆抗体、酶联免疫检测试剂盒及其应用 |
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| EP1957534A1 (en) | 2005-11-09 | 2008-08-20 | Pharmexa A/S | Therapeutic vaccines targeting hmgb1 |
| WO2007076200A2 (en) | 2005-11-28 | 2007-07-05 | Medimmune, Inc. | Antagonists of hmgb1 and/or rage and methods of use thereof |
| CA2914170C (en) * | 2006-09-08 | 2018-10-30 | Abbvie Bahamas Ltd. | Interleukin-13 binding proteins |
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2004
- 2004-09-10 CA CA2882022A patent/CA2882022A1/en not_active Abandoned
- 2004-09-10 CN CNA2004800332177A patent/CN1878793A/zh active Pending
- 2004-09-10 AU AU2004272607A patent/AU2004272607B2/en not_active Ceased
- 2004-09-10 JP JP2006526305A patent/JP4792392B2/ja not_active Expired - Fee Related
- 2004-09-10 WO PCT/US2004/029527 patent/WO2005026209A2/en not_active Ceased
- 2004-09-10 EP EP04788671A patent/EP1668035A2/en not_active Withdrawn
- 2004-09-10 CA CA2538763A patent/CA2538763C/en not_active Expired - Fee Related
- 2004-09-10 US US10/938,992 patent/US7288250B2/en not_active Expired - Fee Related
-
2007
- 2007-09-20 US US11/903,129 patent/US7632500B2/en not_active Expired - Lifetime
- 2007-10-15 US US11/974,923 patent/US20090148453A1/en not_active Abandoned
-
2010
- 2010-10-04 US US12/897,453 patent/US8846047B2/en not_active Expired - Fee Related
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2011
- 2011-05-27 JP JP2011118559A patent/JP5513441B2/ja not_active Expired - Fee Related
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Also Published As
| Publication number | Publication date |
|---|---|
| CA2538763A1 (en) | 2005-03-24 |
| JP5513441B2 (ja) | 2014-06-04 |
| JP4792392B2 (ja) | 2011-10-12 |
| WO2005026209A3 (en) | 2005-09-15 |
| JP2011241219A (ja) | 2011-12-01 |
| US20090148453A1 (en) | 2009-06-11 |
| US7288250B2 (en) | 2007-10-30 |
| US20110217292A1 (en) | 2011-09-08 |
| US8846047B2 (en) | 2014-09-30 |
| US20080113385A1 (en) | 2008-05-15 |
| US7632500B2 (en) | 2009-12-15 |
| CA2882022A1 (en) | 2005-03-24 |
| US20050152903A1 (en) | 2005-07-14 |
| AU2004272607A1 (en) | 2005-03-24 |
| AU2004272607B2 (en) | 2008-11-06 |
| EP1668035A2 (en) | 2006-06-14 |
| JP2007527406A (ja) | 2007-09-27 |
| CA2538763C (en) | 2015-05-05 |
| WO2005026209A2 (en) | 2005-03-24 |
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