IT1291366B1 - Composizione farmaceutica antivirale comprendente acido glicirrizico ed almeno una proteina dotata di attivita' antivirale - Google Patents

Composizione farmaceutica antivirale comprendente acido glicirrizico ed almeno una proteina dotata di attivita' antivirale

Info

Publication number
IT1291366B1
IT1291366B1 IT97MI001119A ITMI971119A IT1291366B1 IT 1291366 B1 IT1291366 B1 IT 1291366B1 IT 97MI001119 A IT97MI001119 A IT 97MI001119A IT MI971119 A ITMI971119 A IT MI971119A IT 1291366 B1 IT1291366 B1 IT 1291366B1
Authority
IT
Italy
Prior art keywords
antiviral
glycyrhizic
protein
acid
pharmaceutical composition
Prior art date
Application number
IT97MI001119A
Other languages
English (en)
Inventor
Mario Pinza
Raffaello Pompei
Original Assignee
Angelini Ricerche Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angelini Ricerche Spa filed Critical Angelini Ricerche Spa
Publication of ITMI971119A0 publication Critical patent/ITMI971119A0/it
Priority to IT97MI001119A priority Critical patent/IT1291366B1/it
Priority to PT98925588T priority patent/PT980254E/pt
Priority to SI9830118T priority patent/SI0980254T1/xx
Priority to AT98925588T priority patent/ATE212232T1/de
Priority to CN98805037A priority patent/CN1114447C/zh
Priority to DK98925588T priority patent/DK0980254T3/da
Priority to TR1999/02730T priority patent/TR199902730T2/xx
Priority to AU77646/98A priority patent/AU740944B2/en
Priority to DE69803565T priority patent/DE69803565T2/de
Priority to HU0002985A priority patent/HU224956B1/hu
Priority to PL98336802A priority patent/PL189218B1/pl
Priority to GEAP19985126A priority patent/GEP20022672B/en
Priority to KR1019997010372A priority patent/KR100592193B1/ko
Priority to ES98925588T priority patent/ES2170501T3/es
Priority to CA002289550A priority patent/CA2289550A1/en
Priority to US09/423,611 priority patent/US6329339B1/en
Priority to JP54879998A priority patent/JP2001525814A/ja
Priority to SK1544-99A priority patent/SK283584B6/sk
Priority to PCT/EP1998/002797 priority patent/WO1998051334A1/en
Priority to CZ19993991A priority patent/CZ291932B6/cs
Priority to EA199901024A priority patent/EA003126B1/ru
Priority to EP98925588A priority patent/EP0980254B1/en
Priority to IL13265198A priority patent/IL132651A0/xx
Priority to ZA983917A priority patent/ZA983917B/xx
Priority to ARP980102218A priority patent/AR012849A1/es
Priority to UA99126790A priority patent/UA63955C2/uk
Publication of ITMI971119A1 publication Critical patent/ITMI971119A1/it
Application granted granted Critical
Publication of IT1291366B1 publication Critical patent/IT1291366B1/it
Priority to IL132651A priority patent/IL132651A/en
Priority to BG103968A priority patent/BG64748B1/bg
Priority to HK00107849A priority patent/HK1028347A1/xx
Priority to JP2008331229A priority patent/JP2009102370A/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT97MI001119A 1997-05-14 1997-05-14 Composizione farmaceutica antivirale comprendente acido glicirrizico ed almeno una proteina dotata di attivita' antivirale IT1291366B1 (it)

Priority Applications (30)

Application Number Priority Date Filing Date Title
IT97MI001119A IT1291366B1 (it) 1997-05-14 1997-05-14 Composizione farmaceutica antivirale comprendente acido glicirrizico ed almeno una proteina dotata di attivita' antivirale
CA002289550A CA2289550A1 (en) 1997-05-14 1998-05-06 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral activity
KR1019997010372A KR100592193B1 (ko) 1997-05-14 1998-05-06 글리시리진산과 항바이러스 활성을 갖는 적어도 하나의 단백질로 이루어진 항바이러스성 제약 조성물
AT98925588T ATE212232T1 (de) 1997-05-14 1998-05-06 Antivirale pharmazeutische zusammensetzungen welche glycyrrhizinsäure und mindestens ein protein mit antiviraler wirksamkeit enthalten
CN98805037A CN1114447C (zh) 1997-05-14 1998-05-06 含有甘草酸和至少一种具有抗病毒活性的蛋白质的抗病毒药物组合物
DK98925588T DK0980254T3 (da) 1997-05-14 1998-05-06 Farmaceutisk antiviruspræparat omfattende glycyrrhizinsyre og mindst et protein udstyret med antiviral aktivitet
TR1999/02730T TR199902730T2 (xx) 1997-05-14 1998-05-06 Glikrizikasit ve antiviral etkinlik kazand�r�lm�� en az�ndan bir proteini i�eren farmas�tik antiviral bile�im.
SK1544-99A SK283584B6 (sk) 1997-05-14 1998-05-06 Farmaceutický prostriedok s antivírusovým účinkom obsahujúci kyselinu glycyrhizovú a aspoň jeden proteín prejavujúci antivírusový účinok
DE69803565T DE69803565T2 (de) 1997-05-14 1998-05-06 Antivirale pharmazeutische zusammensetzungen welche glycyrrhizinsäure und mindestens ein protein mit antiviraler wirksamkeit enthalten
HU0002985A HU224956B1 (en) 1997-05-14 1998-05-06 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral activity
PL98336802A PL189218B1 (pl) 1997-05-14 1998-05-06 Przeciwwirusowa kompozycja farmaceutyczna obejmująca kwas glicyryzowy i przynajmniej jedno białko oaktywności przeciwwirusowej
GEAP19985126A GEP20022672B (en) 1997-05-14 1998-05-06 Pharmaceutical Composition
SI9830118T SI0980254T1 (en) 1997-05-14 1998-05-06 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral activity
ES98925588T ES2170501T3 (es) 1997-05-14 1998-05-06 Composicion farmaceutica antivirica que comprende acido glicirrizico y al menos una proteina que posee actividad antivirica.
PT98925588T PT980254E (pt) 1997-05-14 1998-05-06 Composicao farmaceutica anti-viral compreendendo acido glicirizico e pelo menos uma proteina dotada de actividade anti-viral
US09/423,611 US6329339B1 (en) 1997-05-14 1998-05-06 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral activity
JP54879998A JP2001525814A (ja) 1997-05-14 1998-05-06 グリシルリジン酸及び抗ウイルス活性を有する蛋白質を少なくとも一つ含む、抗ウイルス薬剤組成物
AU77646/98A AU740944B2 (en) 1997-05-14 1998-05-06 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral activity
PCT/EP1998/002797 WO1998051334A1 (en) 1997-05-14 1998-05-06 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral activity
CZ19993991A CZ291932B6 (cs) 1997-05-14 1998-05-06 Farmaceutický prostředek s antivirovým účinkem, obsahující kyselinu glycyrrhizovou a alespoň jeden protein projevující antivirový účinek
EA199901024A EA003126B1 (ru) 1997-05-14 1998-05-06 Антивирусная фармацевтическая композиция, содержащая глицирризиновую кислоту и, по меньшей мере, один белок, имеющий активность в отношении вируса простого герпеса типа 1
EP98925588A EP0980254B1 (en) 1997-05-14 1998-05-06 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral activity
IL13265198A IL132651A0 (en) 1997-05-14 1998-05-06 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral acitvity
ZA983917A ZA983917B (en) 1997-05-14 1998-05-08 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral activity
ARP980102218A AR012849A1 (es) 1997-05-14 1998-05-13 Composicion farmaceutica antivirica.
UA99126790A UA63955C2 (uk) 1997-05-14 1998-06-05 Фармацевтична антивірусна композиція
IL132651A IL132651A (en) 1997-05-14 1999-10-29 Antiviral pharmaceutical preparation containing glyceric acid and at least one protein with antiviral activity
BG103968A BG64748B1 (bg) 1997-05-14 1999-12-08 Противовирусен фармацевтичен състав
HK00107849A HK1028347A1 (en) 1997-05-14 2000-12-07 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral activity
JP2008331229A JP2009102370A (ja) 1997-05-14 2008-12-25 グリシルリジン酸及び抗ウイルス活性を有する蛋白質を少なくとも一つ含む、抗ウイルス薬剤組成物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI001119A IT1291366B1 (it) 1997-05-14 1997-05-14 Composizione farmaceutica antivirale comprendente acido glicirrizico ed almeno una proteina dotata di attivita' antivirale

Publications (3)

Publication Number Publication Date
ITMI971119A0 ITMI971119A0 (it) 1997-05-14
ITMI971119A1 ITMI971119A1 (it) 1998-11-14
IT1291366B1 true IT1291366B1 (it) 1999-01-07

Family

ID=11377123

Family Applications (1)

Application Number Title Priority Date Filing Date
IT97MI001119A IT1291366B1 (it) 1997-05-14 1997-05-14 Composizione farmaceutica antivirale comprendente acido glicirrizico ed almeno una proteina dotata di attivita' antivirale

Country Status (27)

Country Link
US (1) US6329339B1 (it)
EP (1) EP0980254B1 (it)
JP (2) JP2001525814A (it)
KR (1) KR100592193B1 (it)
CN (1) CN1114447C (it)
AR (1) AR012849A1 (it)
AT (1) ATE212232T1 (it)
AU (1) AU740944B2 (it)
BG (1) BG64748B1 (it)
CA (1) CA2289550A1 (it)
CZ (1) CZ291932B6 (it)
DE (1) DE69803565T2 (it)
DK (1) DK0980254T3 (it)
EA (1) EA003126B1 (it)
ES (1) ES2170501T3 (it)
GE (1) GEP20022672B (it)
HK (1) HK1028347A1 (it)
HU (1) HU224956B1 (it)
IL (2) IL132651A0 (it)
IT (1) IT1291366B1 (it)
PL (1) PL189218B1 (it)
PT (1) PT980254E (it)
SK (1) SK283584B6 (it)
TR (1) TR199902730T2 (it)
UA (1) UA63955C2 (it)
WO (1) WO1998051334A1 (it)
ZA (1) ZA983917B (it)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6303321B1 (en) * 1999-02-11 2001-10-16 North Shore-Long Island Jewish Research Institute Methods for diagnosing sepsis
US7151082B2 (en) * 1999-02-11 2006-12-19 The Feinstein Institute For Medical Research Antagonists of HMG1 for treating inflammatory conditions
US7304034B2 (en) * 2001-05-15 2007-12-04 The Feinstein Institute For Medical Research Use of HMGB fragments as anti-inflammatory agents
WO2003088914A2 (en) * 2002-04-18 2003-10-30 The University Of Iowa Research Foundation Methods of inhibiting and treating bacterial biofilms by metal chelators
US7696169B2 (en) * 2003-06-06 2010-04-13 The Feinstein Institute For Medical Research Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
EP1668035A2 (en) * 2003-09-11 2006-06-14 Critical Therapeutics, Inc. Monoclonal antibodies against hmgb1
WO2007084253A2 (en) * 2005-11-28 2007-07-26 Medimmune, Inc. High affinity antibodies against hmgb1 and methods of use thereof
WO2007011606A2 (en) * 2005-07-18 2007-01-25 Critical Therapeutics, Inc. USE OF HMGBl ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY SKIN CONDITIONS
IT1391170B1 (it) * 2008-08-07 2011-11-18 D M G Italia S R L Composizione topica intra-nasale utilizzabile in caso di ostruzione nasale
US9416151B2 (en) 2010-08-25 2016-08-16 Lurong ZHANG Use of glycyrrhetinic acid, glycyrrhizic acid and related compounds for prevention and/or treatment of pulmonary fibrosis
EP2608783B1 (en) * 2010-08-25 2018-09-19 Lurong Zhang Use of glycyrrhetinic acid, glycyrrhizic acid and related compounds for prevention and/or treatment of pulmonary fibrosis
KR102437992B1 (ko) * 2014-02-21 2022-08-29 고쿠리츠 다이가쿠 호우징 도쿄 가이요우 다이가쿠 노로 바이러스 불활화제 및 그 제조 방법, 노로 바이러스 불활화 방법, 노로 바이러스 불활화용 라이소자임류의 제조 방법, 노로 바이러스 감염의 예방약 또는 치료약, 그리고 노로 바이러스 불활화용 피부 외용제
EP3419629A4 (en) * 2016-02-25 2019-10-30 Applied Biological Laboratories, Inc. COMPOSITIONS AND PROCEDURES FOR PROTECTION AGAINST AIRBORNE PATHOGENES AND IRRITATES
CN109022351B (zh) * 2018-09-28 2021-10-19 广州奇龙生物科技有限公司 重组人溶菌酶的新应用
CN112805027B (zh) * 2020-04-27 2023-10-10 广州新创忆药物临床研究有限公司 一种抗新冠病毒感染的药物与应用
CN112135625B (zh) * 2020-04-27 2021-07-06 广州新创忆药物临床研究有限公司 一种预防或治疗covid-19新冠肺炎的药物及其应用
US20220305092A1 (en) * 2020-04-27 2022-09-29 Guangzhou Century Clinical Research Co., Ltd Medicament and food for preventing or treating novel coronavirus pneumonia covid-19 and use thereof
MX2021005280A (es) 2021-05-04 2022-02-23 Spv Timser S A P I De C V Composicion farmaceutica que contiene triterpenoides pentaciclicos.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH085800B2 (ja) * 1986-12-19 1996-01-24 エーザイ株式会社 塩化リゾチ−ム及びグリチルリチン酸ジカリウム含有水溶液製剤
JP2838720B2 (ja) * 1989-10-31 1998-12-16 ゼリア新薬工業株式会社 安定な点眼剤
JP4056099B2 (ja) * 1996-05-09 2008-03-05 森永乳業株式会社 水生動物の寄生生物性疾患の予防および治療剤

Also Published As

Publication number Publication date
EP0980254B1 (en) 2002-01-23
SK154499A3 (en) 2000-08-14
AU7764698A (en) 1998-12-08
IL132651A (en) 2006-10-31
CZ291932B6 (cs) 2003-06-18
SK283584B6 (sk) 2003-10-07
DE69803565T2 (de) 2002-08-08
IL132651A0 (en) 2001-03-19
DK0980254T3 (da) 2002-05-06
ITMI971119A0 (it) 1997-05-14
UA63955C2 (uk) 2004-02-16
EA199901024A1 (ru) 2000-06-26
KR100592193B1 (ko) 2006-06-23
HUP0002985A2 (hu) 2001-01-29
PL336802A1 (en) 2000-07-17
ZA983917B (en) 1998-11-09
ES2170501T3 (es) 2002-08-01
AR012849A1 (es) 2000-11-22
GEP20022672B (en) 2002-04-25
CA2289550A1 (en) 1998-11-19
CZ399199A3 (cs) 2000-04-12
JP2001525814A (ja) 2001-12-11
HK1028347A1 (en) 2001-02-16
ITMI971119A1 (it) 1998-11-14
WO1998051334A1 (en) 1998-11-19
EP0980254A1 (en) 2000-02-23
KR20010012419A (ko) 2001-02-15
PT980254E (pt) 2002-07-31
HUP0002985A3 (en) 2001-04-28
AU740944B2 (en) 2001-11-15
CN1255859A (zh) 2000-06-07
DE69803565D1 (de) 2002-03-14
JP2009102370A (ja) 2009-05-14
US6329339B1 (en) 2001-12-11
EA003126B1 (ru) 2003-02-27
PL189218B1 (pl) 2005-07-29
BG64748B1 (bg) 2006-02-28
CN1114447C (zh) 2003-07-16
HU224956B1 (en) 2006-04-28
TR199902730T2 (xx) 2000-02-21
ATE212232T1 (de) 2002-02-15
BG103968A (en) 2000-07-31

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