IT1291366B1 - Composizione farmaceutica antivirale comprendente acido glicirrizico ed almeno una proteina dotata di attivita' antivirale - Google Patents

Composizione farmaceutica antivirale comprendente acido glicirrizico ed almeno una proteina dotata di attivita' antivirale

Info

Publication number
IT1291366B1
IT1291366B1 IT97MI001119A ITMI971119A IT1291366B1 IT 1291366 B1 IT1291366 B1 IT 1291366B1 IT 97MI001119 A IT97MI001119 A IT 97MI001119A IT MI971119 A ITMI971119 A IT MI971119A IT 1291366 B1 IT1291366 B1 IT 1291366B1
Authority
IT
Italy
Prior art keywords
antiviral
glycyrhizic
protein
acid
pharmaceutical composition
Prior art date
Application number
IT97MI001119A
Other languages
English (en)
Inventor
Mario Pinza
Raffaello Pompei
Original Assignee
Angelini Ricerche Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angelini Ricerche Spa filed Critical Angelini Ricerche Spa
Publication of ITMI971119A0 publication Critical patent/ITMI971119A0/it
Priority to IT97MI001119A priority Critical patent/IT1291366B1/it
Priority to ES98925588T priority patent/ES2170501T3/es
Priority to JP54879998A priority patent/JP2001525814A/ja
Priority to EP98925588A priority patent/EP0980254B1/en
Priority to GEAP19985126A priority patent/GEP20022672B/en
Priority to PCT/EP1998/002797 priority patent/WO1998051334A1/en
Priority to IL13265198A priority patent/IL132651A0/xx
Priority to PL98336802A priority patent/PL189218B1/pl
Priority to SK1544-99A priority patent/SK283584B6/sk
Priority to HU0002985A priority patent/HU224956B1/hu
Priority to CZ19993991A priority patent/CZ291932B6/cs
Priority to AU77646/98A priority patent/AU740944B2/en
Priority to SI9830118T priority patent/SI0980254T1/xx
Priority to AT98925588T priority patent/ATE212232T1/de
Priority to CN98805037A priority patent/CN1114447C/zh
Priority to EA199901024A priority patent/EA003126B1/ru
Priority to TR1999/02730T priority patent/TR199902730T2/xx
Priority to KR1019997010372A priority patent/KR100592193B1/ko
Priority to DE69803565T priority patent/DE69803565T2/de
Priority to DK98925588T priority patent/DK0980254T3/da
Priority to CA002289550A priority patent/CA2289550A1/en
Priority to US09/423,611 priority patent/US6329339B1/en
Priority to PT98925588T priority patent/PT980254E/pt
Priority to ZA983917A priority patent/ZA983917B/xx
Priority to ARP980102218A priority patent/AR012849A1/es
Priority to UA99126790A priority patent/UA63955C2/uk
Publication of ITMI971119A1 publication Critical patent/ITMI971119A1/it
Application granted granted Critical
Publication of IT1291366B1 publication Critical patent/IT1291366B1/it
Priority to IL132651A priority patent/IL132651A/en
Priority to BG103968A priority patent/BG64748B1/bg
Priority to HK00107849A priority patent/HK1028347A1/xx
Priority to JP2008331229A priority patent/JP2009102370A/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT97MI001119A 1997-05-14 1997-05-14 Composizione farmaceutica antivirale comprendente acido glicirrizico ed almeno una proteina dotata di attivita' antivirale IT1291366B1 (it)

Priority Applications (30)

Application Number Priority Date Filing Date Title
IT97MI001119A IT1291366B1 (it) 1997-05-14 1997-05-14 Composizione farmaceutica antivirale comprendente acido glicirrizico ed almeno una proteina dotata di attivita' antivirale
CN98805037A CN1114447C (zh) 1997-05-14 1998-05-06 含有甘草酸和至少一种具有抗病毒活性的蛋白质的抗病毒药物组合物
SI9830118T SI0980254T1 (en) 1997-05-14 1998-05-06 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral activity
EP98925588A EP0980254B1 (en) 1997-05-14 1998-05-06 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral activity
GEAP19985126A GEP20022672B (en) 1997-05-14 1998-05-06 Pharmaceutical Composition
PCT/EP1998/002797 WO1998051334A1 (en) 1997-05-14 1998-05-06 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral activity
IL13265198A IL132651A0 (en) 1997-05-14 1998-05-06 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral acitvity
KR1019997010372A KR100592193B1 (ko) 1997-05-14 1998-05-06 글리시리진산과 항바이러스 활성을 갖는 적어도 하나의 단백질로 이루어진 항바이러스성 제약 조성물
SK1544-99A SK283584B6 (sk) 1997-05-14 1998-05-06 Farmaceutický prostriedok s antivírusovým účinkom obsahujúci kyselinu glycyrhizovú a aspoň jeden proteín prejavujúci antivírusový účinok
HU0002985A HU224956B1 (en) 1997-05-14 1998-05-06 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral activity
CZ19993991A CZ291932B6 (cs) 1997-05-14 1998-05-06 Farmaceutický prostředek s antivirovým účinkem, obsahující kyselinu glycyrrhizovou a alespoň jeden protein projevující antivirový účinek
AU77646/98A AU740944B2 (en) 1997-05-14 1998-05-06 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral activity
JP54879998A JP2001525814A (ja) 1997-05-14 1998-05-06 グリシルリジン酸及び抗ウイルス活性を有する蛋白質を少なくとも一つ含む、抗ウイルス薬剤組成物
AT98925588T ATE212232T1 (de) 1997-05-14 1998-05-06 Antivirale pharmazeutische zusammensetzungen welche glycyrrhizinsäure und mindestens ein protein mit antiviraler wirksamkeit enthalten
ES98925588T ES2170501T3 (es) 1997-05-14 1998-05-06 Composicion farmaceutica antivirica que comprende acido glicirrizico y al menos una proteina que posee actividad antivirica.
EA199901024A EA003126B1 (ru) 1997-05-14 1998-05-06 Антивирусная фармацевтическая композиция, содержащая глицирризиновую кислоту и, по меньшей мере, один белок, имеющий активность в отношении вируса простого герпеса типа 1
TR1999/02730T TR199902730T2 (xx) 1997-05-14 1998-05-06 Glikrizikasit ve antiviral etkinlik kazand�r�lm�� en az�ndan bir proteini i�eren farmas�tik antiviral bile�im.
PL98336802A PL189218B1 (pl) 1997-05-14 1998-05-06 Przeciwwirusowa kompozycja farmaceutyczna obejmująca kwas glicyryzowy i przynajmniej jedno białko oaktywności przeciwwirusowej
DE69803565T DE69803565T2 (de) 1997-05-14 1998-05-06 Antivirale pharmazeutische zusammensetzungen welche glycyrrhizinsäure und mindestens ein protein mit antiviraler wirksamkeit enthalten
DK98925588T DK0980254T3 (da) 1997-05-14 1998-05-06 Farmaceutisk antiviruspræparat omfattende glycyrrhizinsyre og mindst et protein udstyret med antiviral aktivitet
CA002289550A CA2289550A1 (en) 1997-05-14 1998-05-06 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral activity
US09/423,611 US6329339B1 (en) 1997-05-14 1998-05-06 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral activity
PT98925588T PT980254E (pt) 1997-05-14 1998-05-06 Composicao farmaceutica anti-viral compreendendo acido glicirizico e pelo menos uma proteina dotada de actividade anti-viral
ZA983917A ZA983917B (en) 1997-05-14 1998-05-08 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral activity
ARP980102218A AR012849A1 (es) 1997-05-14 1998-05-13 Composicion farmaceutica antivirica.
UA99126790A UA63955C2 (uk) 1997-05-14 1998-06-05 Фармацевтична антивірусна композиція
IL132651A IL132651A (en) 1997-05-14 1999-10-29 Antiviral pharmaceutical preparation containing glyceric acid and at least one protein with antiviral activity
BG103968A BG64748B1 (bg) 1997-05-14 1999-12-08 Противовирусен фармацевтичен състав
HK00107849A HK1028347A1 (en) 1997-05-14 2000-12-07 Pharmaceutical antiviral composition comprising glycyrrhizic acid and at least one protein endowed with antiviral activity
JP2008331229A JP2009102370A (ja) 1997-05-14 2008-12-25 グリシルリジン酸及び抗ウイルス活性を有する蛋白質を少なくとも一つ含む、抗ウイルス薬剤組成物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI001119A IT1291366B1 (it) 1997-05-14 1997-05-14 Composizione farmaceutica antivirale comprendente acido glicirrizico ed almeno una proteina dotata di attivita' antivirale

Publications (3)

Publication Number Publication Date
ITMI971119A0 ITMI971119A0 (it) 1997-05-14
ITMI971119A1 ITMI971119A1 (it) 1998-11-14
IT1291366B1 true IT1291366B1 (it) 1999-01-07

Family

ID=11377123

Family Applications (1)

Application Number Title Priority Date Filing Date
IT97MI001119A IT1291366B1 (it) 1997-05-14 1997-05-14 Composizione farmaceutica antivirale comprendente acido glicirrizico ed almeno una proteina dotata di attivita' antivirale

Country Status (27)

Country Link
US (1) US6329339B1 (it)
EP (1) EP0980254B1 (it)
JP (2) JP2001525814A (it)
KR (1) KR100592193B1 (it)
CN (1) CN1114447C (it)
AR (1) AR012849A1 (it)
AT (1) ATE212232T1 (it)
AU (1) AU740944B2 (it)
BG (1) BG64748B1 (it)
CA (1) CA2289550A1 (it)
CZ (1) CZ291932B6 (it)
DE (1) DE69803565T2 (it)
DK (1) DK0980254T3 (it)
EA (1) EA003126B1 (it)
ES (1) ES2170501T3 (it)
GE (1) GEP20022672B (it)
HK (1) HK1028347A1 (it)
HU (1) HU224956B1 (it)
IL (2) IL132651A0 (it)
IT (1) IT1291366B1 (it)
PL (1) PL189218B1 (it)
PT (1) PT980254E (it)
SK (1) SK283584B6 (it)
TR (1) TR199902730T2 (it)
UA (1) UA63955C2 (it)
WO (1) WO1998051334A1 (it)
ZA (1) ZA983917B (it)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6303321B1 (en) * 1999-02-11 2001-10-16 North Shore-Long Island Jewish Research Institute Methods for diagnosing sepsis
US7151082B2 (en) * 1999-02-11 2006-12-19 The Feinstein Institute For Medical Research Antagonists of HMG1 for treating inflammatory conditions
US7304034B2 (en) * 2001-05-15 2007-12-04 The Feinstein Institute For Medical Research Use of HMGB fragments as anti-inflammatory agents
AU2003225073A1 (en) * 2002-04-18 2003-11-03 The University Of Iowa Research Foundation Methods of inhibiting and treating bacterial biofilms by metal chelators
US7696169B2 (en) * 2003-06-06 2010-04-13 The Feinstein Institute For Medical Research Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
AU2004272607B2 (en) * 2003-09-11 2008-11-06 Cornerstone Therapeutics Inc. Monoclonal antibodies against HMGB1
US20100040608A1 (en) * 2005-07-18 2010-02-18 Marie Wahren-Herlenius Use of HMGB1 antagonists for the treatment of inflammatory skin conditions
US20080311122A1 (en) * 2005-11-28 2008-12-18 Medimmune, Llc Antagonists of Hmgb1 and/or Rage and Methods of Use Thereof
IT1391170B1 (it) * 2008-08-07 2011-11-18 D M G Italia S R L Composizione topica intra-nasale utilizzabile in caso di ostruzione nasale
EP2608783B1 (en) * 2010-08-25 2018-09-19 Lurong Zhang Use of glycyrrhetinic acid, glycyrrhizic acid and related compounds for prevention and/or treatment of pulmonary fibrosis
US9416151B2 (en) 2010-08-25 2016-08-16 Lurong ZHANG Use of glycyrrhetinic acid, glycyrrhizic acid and related compounds for prevention and/or treatment of pulmonary fibrosis
JP5806434B1 (ja) * 2014-02-21 2015-11-10 国立大学法人東京海洋大学 ノロウィルス不活化剤及びその製造方法、ノロウィルス不活化方法、ノロウィルス不活化用リゾチーム類の製造方法、ノロウィルス感染の予防薬又は治療薬、並びにノロウィルス不活化用皮膚外用剤
CN109069520A (zh) * 2016-02-25 2018-12-21 应用生物实验室公司 保护空气传播的病原体和刺激物的组合物和方法
CN109022351B (zh) * 2018-09-28 2021-10-19 广州奇龙生物科技有限公司 重组人溶菌酶的新应用
CN113304253A (zh) * 2020-04-27 2021-08-27 湘北威尔曼制药股份有限公司 一种辅助预防或辅助治疗新冠肺炎的食物及其应用
US20230158124A1 (en) * 2020-04-27 2023-05-25 Guangzhou Century Clinical Research Co., Ltd Drug, food and application of anti-coronavirus infection
CN112135625B (zh) * 2020-04-27 2021-07-06 广州新创忆药物临床研究有限公司 一种预防或治疗covid-19新冠肺炎的药物及其应用
MX2021005280A (es) 2021-05-04 2022-02-23 Spv Timser S A P I De C V Composicion farmaceutica que contiene triterpenoides pentaciclicos.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH085800B2 (ja) * 1986-12-19 1996-01-24 エーザイ株式会社 塩化リゾチ−ム及びグリチルリチン酸ジカリウム含有水溶液製剤
JP2838720B2 (ja) * 1989-10-31 1998-12-16 ゼリア新薬工業株式会社 安定な点眼剤
JP4056099B2 (ja) * 1996-05-09 2008-03-05 森永乳業株式会社 水生動物の寄生生物性疾患の予防および治療剤

Also Published As

Publication number Publication date
SK283584B6 (sk) 2003-10-07
PT980254E (pt) 2002-07-31
AU740944B2 (en) 2001-11-15
WO1998051334A1 (en) 1998-11-19
AU7764698A (en) 1998-12-08
CZ399199A3 (cs) 2000-04-12
CN1114447C (zh) 2003-07-16
EA199901024A1 (ru) 2000-06-26
DE69803565D1 (de) 2002-03-14
PL189218B1 (pl) 2005-07-29
BG64748B1 (bg) 2006-02-28
EA003126B1 (ru) 2003-02-27
HK1028347A1 (en) 2001-02-16
TR199902730T2 (xx) 2000-02-21
SK154499A3 (en) 2000-08-14
GEP20022672B (en) 2002-04-25
EP0980254A1 (en) 2000-02-23
CZ291932B6 (cs) 2003-06-18
EP0980254B1 (en) 2002-01-23
CN1255859A (zh) 2000-06-07
ITMI971119A0 (it) 1997-05-14
ITMI971119A1 (it) 1998-11-14
JP2001525814A (ja) 2001-12-11
IL132651A0 (en) 2001-03-19
DK0980254T3 (da) 2002-05-06
CA2289550A1 (en) 1998-11-19
BG103968A (en) 2000-07-31
ATE212232T1 (de) 2002-02-15
DE69803565T2 (de) 2002-08-08
KR20010012419A (ko) 2001-02-15
UA63955C2 (uk) 2004-02-16
IL132651A (en) 2006-10-31
ES2170501T3 (es) 2002-08-01
AR012849A1 (es) 2000-11-22
PL336802A1 (en) 2000-07-17
HU224956B1 (en) 2006-04-28
US6329339B1 (en) 2001-12-11
KR100592193B1 (ko) 2006-06-23
HUP0002985A2 (hu) 2001-01-29
ZA983917B (en) 1998-11-09
HUP0002985A3 (en) 2001-04-28
JP2009102370A (ja) 2009-05-14

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