CN1720225B - 具有5-羟色胺受体亲和性的n-芳基磺酰-3-取代吲哚及其制备方法和含有其的药物组合物 - Google Patents

具有5-羟色胺受体亲和性的n-芳基磺酰-3-取代吲哚及其制备方法和含有其的药物组合物 Download PDF

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CN1720225B
CN1720225B CN038254883A CN03825488A CN1720225B CN 1720225 B CN1720225 B CN 1720225B CN 038254883 A CN038254883 A CN 038254883A CN 03825488 A CN03825488 A CN 03825488A CN 1720225 B CN1720225 B CN 1720225B
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ylmethyl
methylpiperazine
indoles
indol
bromo
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CN1720225A (zh
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文卡塔·萨蒂亚·尼罗齐·罗摩克里希纳
弗尔卡斯·什里克瑞什那·希尔萨斯
拉玛·萨斯特里·甘朴汉帕蒂
文卡塔·萨蒂亚·维拉哈德劳·瓦德莱姆蒂·拉奥
文卡特斯瓦卢·贾斯提
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Suven Life Sciences Ltd
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CN038254883A 2002-11-28 2003-06-05 具有5-羟色胺受体亲和性的n-芳基磺酰-3-取代吲哚及其制备方法和含有其的药物组合物 Expired - Lifetime CN1720225B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN884MA2002 2002-11-28
IN884/MAS/2002 2002-11-28
PCT/IN2003/000209 WO2004048330A1 (en) 2002-11-28 2003-06-05 N-arylsulfonyl-3-substituted indoles having serotonin receptor affinity, process for their preparation and pharmaceutical composition containing them

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CN200910134498XA Division CN101544592B (zh) 2002-11-28 2003-06-05 N-芳基磺酰-3-取代吲哚制备的替代方法

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CN1720225A CN1720225A (zh) 2006-01-11
CN1720225B true CN1720225B (zh) 2011-05-18

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CN038254883A Expired - Lifetime CN1720225B (zh) 2002-11-28 2003-06-05 具有5-羟色胺受体亲和性的n-芳基磺酰-3-取代吲哚及其制备方法和含有其的药物组合物
CN200910134498XA Expired - Lifetime CN101544592B (zh) 2002-11-28 2003-06-05 N-芳基磺酰-3-取代吲哚制备的替代方法

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US (1) US7875605B2 (https=)
EP (1) EP1581492B1 (https=)
JP (1) JP4559230B2 (https=)
KR (1) KR100818508B1 (https=)
CN (2) CN1720225B (https=)
AT (1) ATE401307T1 (https=)
AU (1) AU2003237599B2 (https=)
BR (2) BRPI0315959C1 (https=)
CA (1) CA2509982C (https=)
CY (1) CY1108786T1 (https=)
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AU2004312229B2 (en) 2004-01-02 2010-05-20 Suven Life Sciences Limited Novel Indeno[2,1a]indenes and isoindolo[2,1-a]indoles
EP2392571A3 (en) 2005-07-29 2012-03-14 F. Hoffmann-La Roche AG Indol-3-yl-carbonyl-piperidin and piperazin derivatives
WO2007020653A1 (en) * 2005-08-12 2007-02-22 Suven Life Sciences Limited Thioether derivatives as functional 5-ht6 ligands
BRPI0520579B8 (pt) 2005-08-12 2021-05-25 Suven Life Sciences Ltd composto, processo para a preparação de um composto e composição farmacêutica
KR101250820B1 (ko) 2005-08-16 2013-04-04 수벤 라이프 사이언시스 리미티드 개선된 로사르탄 제조 방법
US20100041669A1 (en) * 2007-01-08 2010-02-18 Venkata Satya Nirogi Ramakrishna 4-(heterocyclyl)alkyl-n-(arylsulfonyl)indole compounds and their use as 5-ht6 ligands
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EA016594B1 (ru) 2007-05-03 2012-06-29 Сувен Лайф Сайенсиз Лимитед Производные 1-(аминоалкоксиарилсульфонил)индола в качестве 5-нтлигандов
WO2008144263A1 (en) * 2007-05-18 2008-11-27 The Ohio State University Research Foundation Potent indole-3-carbinol-derived antitumor agents
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KR101534136B1 (ko) * 2013-06-11 2015-07-07 이화여자대학교 산학협력단 인돌 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 포함하는 5-ht6 수용체 관련 질환의 예방 또는 치료용 약학적 조성물
HUE036008T2 (hu) 2013-12-02 2018-06-28 Suven Life Sciences Ltd Eljárás 1-[(2-brómfenil)szulfonil]-5-metoxi-3-[(4-metil-1-piperazinil)metil]-1H-indol-dimezilát-monohidrát nagyüzemi léptékben történõ elõállítására
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