CN1644585A - 共价结合的寡核苷酸和小沟结合剂的轭合物 - Google Patents
共价结合的寡核苷酸和小沟结合剂的轭合物 Download PDFInfo
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- CN1644585A CN1644585A CN200410055897.4A CN200410055897A CN1644585A CN 1644585 A CN1644585 A CN 1644585A CN 200410055897 A CN200410055897 A CN 200410055897A CN 1644585 A CN1644585 A CN 1644585A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/173—Purine radicals with 2-deoxyribosyl as the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22
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- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/415,370 US5801155A (en) | 1995-04-03 | 1995-04-03 | Covalently linked oligonucleotide minor grove binder conjugates |
| US08/415,370 | 1995-04-03 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN96194421.8A Division CN1187363C (zh) | 1995-04-03 | 1996-04-03 | 共价结合的寡核苷酸和小沟结合剂的轭合物 |
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| CN1644585A true CN1644585A (zh) | 2005-07-27 |
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Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200410055897.4A Pending CN1644585A (zh) | 1995-04-03 | 1996-04-03 | 共价结合的寡核苷酸和小沟结合剂的轭合物 |
| CN96194421.8A Expired - Lifetime CN1187363C (zh) | 1995-04-03 | 1996-04-03 | 共价结合的寡核苷酸和小沟结合剂的轭合物 |
| CN2009101732576A Pending CN101914099A (zh) | 1995-04-03 | 1996-04-03 | 共价结合的寡核苷酸和小沟结合剂的轭合物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN96194421.8A Expired - Lifetime CN1187363C (zh) | 1995-04-03 | 1996-04-03 | 共价结合的寡核苷酸和小沟结合剂的轭合物 |
| CN2009101732576A Pending CN101914099A (zh) | 1995-04-03 | 1996-04-03 | 共价结合的寡核苷酸和小沟结合剂的轭合物 |
Country Status (12)
| Country | Link |
|---|---|
| US (6) | US5801155A (enExample) |
| EP (1) | EP0819133B1 (enExample) |
| JP (1) | JP4948690B2 (enExample) |
| CN (3) | CN1644585A (enExample) |
| AT (1) | ATE382627T1 (enExample) |
| AU (1) | AU716108B2 (enExample) |
| CA (1) | CA2223678C (enExample) |
| DE (1) | DE69637389T2 (enExample) |
| DK (1) | DK0819133T3 (enExample) |
| ES (1) | ES2300106T3 (enExample) |
| PT (1) | PT819133E (enExample) |
| WO (1) | WO1996032496A2 (enExample) |
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-
1995
- 1995-04-03 US US08/415,370 patent/US5801155A/en not_active Expired - Lifetime
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1996
- 1996-04-03 WO PCT/US1996/004559 patent/WO1996032496A2/en not_active Ceased
- 1996-04-03 DE DE69637389T patent/DE69637389T2/de not_active Expired - Lifetime
- 1996-04-03 ES ES96910723T patent/ES2300106T3/es not_active Expired - Lifetime
- 1996-04-03 DK DK96910723T patent/DK0819133T3/da active
- 1996-04-03 CA CA002223678A patent/CA2223678C/en not_active Expired - Lifetime
- 1996-04-03 CN CN200410055897.4A patent/CN1644585A/zh active Pending
- 1996-04-03 EP EP96910723A patent/EP0819133B1/en not_active Expired - Lifetime
- 1996-04-03 JP JP53105196A patent/JP4948690B2/ja not_active Expired - Lifetime
- 1996-04-03 AT AT96910723T patent/ATE382627T1/de active
- 1996-04-03 AU AU53842/96A patent/AU716108B2/en not_active Expired
- 1996-04-03 PT PT96910723T patent/PT819133E/pt unknown
- 1996-04-03 CN CN96194421.8A patent/CN1187363C/zh not_active Expired - Lifetime
- 1996-04-03 CN CN2009101732576A patent/CN101914099A/zh active Pending
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1998
- 1998-08-27 US US09/141,764 patent/US6084102A/en not_active Expired - Lifetime
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2000
- 2000-02-18 US US09/507,345 patent/US6426408B1/en not_active Expired - Lifetime
- 2000-12-18 US US09/739,928 patent/US6486308B2/en not_active Expired - Lifetime
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2008
- 2008-07-14 US US12/172,999 patent/US7794945B2/en not_active Expired - Fee Related
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| EP0819133B1 (en) | 2008-01-02 |
| US6426408B1 (en) | 2002-07-30 |
| AU716108B2 (en) | 2000-02-17 |
| US6084102A (en) | 2000-07-04 |
| WO1996032496A2 (en) | 1996-10-17 |
| US7794945B2 (en) | 2010-09-14 |
| DE69637389T2 (de) | 2008-12-18 |
| ES2300106T3 (es) | 2008-06-01 |
| DK0819133T3 (da) | 2008-05-13 |
| CA2223678C (en) | 2009-09-08 |
| US6486308B2 (en) | 2002-11-26 |
| PT819133E (pt) | 2008-04-07 |
| DE69637389D1 (de) | 2008-02-14 |
| JP4948690B2 (ja) | 2012-06-06 |
| WO1996032496A3 (en) | 1996-11-28 |
| CN1186496A (zh) | 1998-07-01 |
| AU5384296A (en) | 1996-10-30 |
| ATE382627T1 (de) | 2008-01-15 |
| CN101914099A (zh) | 2010-12-15 |
| CA2223678A1 (en) | 1996-10-17 |
| CN1187363C (zh) | 2005-02-02 |
| US20110275070A1 (en) | 2011-11-10 |
| JPH11504626A (ja) | 1999-04-27 |
| US8465921B2 (en) | 2013-06-18 |
| US20090048427A1 (en) | 2009-02-19 |
| US5801155A (en) | 1998-09-01 |
| US20020052482A1 (en) | 2002-05-02 |
| EP0819133A2 (en) | 1998-01-21 |
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