CN1630718A - 改进的类异戊二烯生产 - Google Patents
改进的类异戊二烯生产 Download PDFInfo
- Publication number
- CN1630718A CN1630718A CNA028113802A CN02811380A CN1630718A CN 1630718 A CN1630718 A CN 1630718A CN A028113802 A CNA028113802 A CN A028113802A CN 02811380 A CN02811380 A CN 02811380A CN 1630718 A CN1630718 A CN 1630718A
- Authority
- CN
- China
- Prior art keywords
- seq
- sequence
- pbbr
- polypeptide
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1229—Phosphotransferases with a phosphate group as acceptor (2.7.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01034—Hydroxymethylglutaryl-CoA reductase (NADPH) (1.1.1.34)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01036—Acetoacetyl-CoA reductase (1.1.1.36)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/03—Acyl groups converted into alkyl on transfer (2.3.3)
- C12Y203/0301—Hydroxymethylglutaryl-CoA synthase (2.3.3.10)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
- C12Y207/01036—Mevalonate kinase (2.7.1.36)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/04—Phosphotransferases with a phosphate group as acceptor (2.7.4)
- C12Y207/04002—Phosphomevalonate kinase (2.7.4.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01033—Diphosphomevalonate decarboxylase (4.1.1.33), i.e. mevalonate-pyrophosphate decarboxylase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Compounds Of Unknown Constitution (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29629901P | 2001-06-06 | 2001-06-06 | |
| US60/296,299 | 2001-06-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1630718A true CN1630718A (zh) | 2005-06-22 |
Family
ID=23141440
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA028113802A Pending CN1630718A (zh) | 2001-06-06 | 2002-06-05 | 改进的类异戊二烯生产 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6989257B2 (enExample) |
| EP (1) | EP1392824B1 (enExample) |
| JP (1) | JP4280627B2 (enExample) |
| KR (1) | KR100704072B1 (enExample) |
| CN (1) | CN1630718A (enExample) |
| AT (1) | ATE405638T1 (enExample) |
| AU (1) | AU2002316966B2 (enExample) |
| CA (1) | CA2449885A1 (enExample) |
| DE (1) | DE60228439D1 (enExample) |
| ES (1) | ES2311613T3 (enExample) |
| WO (1) | WO2002099095A2 (enExample) |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102492701A (zh) * | 2007-06-21 | 2012-06-13 | 日立造船株式会社 | 编码杜仲的甲羟戊酸途径的酶的基因 |
| CN101484584B (zh) * | 2006-05-26 | 2013-03-27 | 阿米瑞斯公司 | 类异戊二烯的生产 |
| US9200296B2 (en) | 2006-05-26 | 2015-12-01 | Amyris Inc. | Production of isoprenoids |
| CN105331518A (zh) * | 2006-05-26 | 2016-02-17 | 阿迈瑞斯公司 | 制造生物有机化合物的设备 |
| CN105339490A (zh) * | 2012-12-20 | 2016-02-17 | 帝斯曼知识产权资产管理有限公司 | 乙酰转移酶及其用于产生类胡萝卜素的用途 |
| CN108285902A (zh) * | 2017-11-03 | 2018-07-17 | 杭州爱蔻思生物科技有限公司 | 生产高价值天然产物的工程菌的构造方法 |
| CN109666683A (zh) * | 2019-02-27 | 2019-04-23 | 昆明理工大学 | 乙酰辅酶A乙酰转移酶基因RKAcaT2及其应用 |
| CN109715796A (zh) * | 2016-03-31 | 2019-05-03 | Jxtg能源株式会社 | 类胡萝卜素的制造方法 |
| CN109777815A (zh) * | 2019-03-28 | 2019-05-21 | 昆明理工大学 | HMG-CoA合成酶基因RKHMGCS及其应用 |
| CN111304260A (zh) * | 2012-06-01 | 2020-06-19 | 朗泽科技新西兰有限公司 | 重组代谢微生物及其用途 |
| CN115003823A (zh) * | 2019-12-26 | 2022-09-02 | 加利福尼亚大学董事会 | 用于生产大麻素和其他异戊二烯化化合物的生物合成平台 |
| CN115605589A (zh) * | 2020-05-15 | 2023-01-13 | 巴斯夫欧洲公司(De) | 改进的用于生产类异戊二烯的方法 |
| CN117965414A (zh) * | 2024-04-01 | 2024-05-03 | 北京微构工场生物技术有限公司 | 一种重组盐单胞菌及其在生产异戊二烯中的应用 |
Families Citing this family (94)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030033626A1 (en) | 2000-07-31 | 2003-02-13 | Hahn Frederick M. | Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms |
| US20030027135A1 (en) | 2001-03-02 | 2003-02-06 | Ecker David J. | Method for rapid detection and identification of bioagents |
| US20040121313A1 (en) | 2002-12-06 | 2004-06-24 | Ecker David J. | Methods for rapid detection and identification of bioagents in organs for transplantation |
| US7666588B2 (en) | 2001-03-02 | 2010-02-23 | Ibis Biosciences, Inc. | Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy |
| US7226739B2 (en) | 2001-03-02 | 2007-06-05 | Isis Pharmaceuticals, Inc | Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations |
| US7217510B2 (en) | 2001-06-26 | 2007-05-15 | Isis Pharmaceuticals, Inc. | Methods for providing bacterial bioagent characterizing information |
| US8073627B2 (en) | 2001-06-26 | 2011-12-06 | Ibis Biosciences, Inc. | System for indentification of pathogens |
| US7172886B2 (en) * | 2001-12-06 | 2007-02-06 | The Regents Of The University Of California | Biosynthesis of isopentenyl pyrophosphate |
| US7192751B2 (en) | 2001-12-06 | 2007-03-20 | The Regents Of The University Of California | Biosynthesis of amorpha-4,11-diene |
| JP2006516193A (ja) | 2002-12-06 | 2006-06-29 | アイシス・ファーマシューティカルス・インコーポレーテッド | ヒトおよび動物における病原体の迅速な同定方法 |
| JP4913588B2 (ja) * | 2003-01-21 | 2012-04-11 | タリオン ファーマシューティカルズ インク. | ファルネシルベンゾジアゼピノンの製造方法及び薬剤としての使用 |
| US8057993B2 (en) | 2003-04-26 | 2011-11-15 | Ibis Biosciences, Inc. | Methods for identification of coronaviruses |
| US8158354B2 (en) | 2003-05-13 | 2012-04-17 | Ibis Biosciences, Inc. | Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture |
| US7964343B2 (en) | 2003-05-13 | 2011-06-21 | Ibis Biosciences, Inc. | Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture |
| KR101190897B1 (ko) | 2003-06-12 | 2012-10-12 | 디에스엠 아이피 어셋츠 비.브이. | 피드백 내성 메발로네이트 키나아제 |
| US20060154349A1 (en) * | 2003-07-08 | 2006-07-13 | Alan Berry | Production of coenzyme q-10 |
| US8394945B2 (en) | 2003-09-11 | 2013-03-12 | Ibis Biosciences, Inc. | Compositions for use in identification of bacteria |
| US8097416B2 (en) | 2003-09-11 | 2012-01-17 | Ibis Biosciences, Inc. | Methods for identification of sepsis-causing bacteria |
| US8546082B2 (en) | 2003-09-11 | 2013-10-01 | Ibis Biosciences, Inc. | Methods for identification of sepsis-causing bacteria |
| US7927794B2 (en) * | 2003-09-29 | 2011-04-19 | The Regents Of The University Of California | Methods for identifying a biosynthetic pathway gene product |
| US7666592B2 (en) | 2004-02-18 | 2010-02-23 | Ibis Biosciences, Inc. | Methods for concurrent identification and quantification of an unknown bioagent |
| ES2379368T3 (es) * | 2004-05-21 | 2012-04-25 | The Regents Of The University Of California | Método para aumentar la producción de compuestos isoprenoides |
| ES2641832T3 (es) | 2004-05-24 | 2017-11-14 | Ibis Biosciences, Inc. | Espectrometría de masas con filtración de iones selectiva por establecimiento de umbrales digitales |
| US20050266411A1 (en) | 2004-05-25 | 2005-12-01 | Hofstadler Steven A | Methods for rapid forensic analysis of mitochondrial DNA |
| US7811753B2 (en) | 2004-07-14 | 2010-10-12 | Ibis Biosciences, Inc. | Methods for repairing degraded DNA |
| JP5074185B2 (ja) * | 2004-08-19 | 2012-11-14 | ディーエスエム アイピー アセッツ ビー.ブイ. | イソプレノイドの生成 |
| WO2006135400A2 (en) | 2004-08-24 | 2006-12-21 | Isis Pharmaceuticals, Inc. | Methods for rapid identification of recombinant organisms |
| WO2006063752A1 (en) * | 2004-12-14 | 2006-06-22 | Dsm Ip Assets B.V. | Improved mevalonate kinase |
| EP1846554A1 (en) | 2005-02-11 | 2007-10-24 | DSMIP Assets B.V. | Fermentive vitamin c production |
| US20060205040A1 (en) | 2005-03-03 | 2006-09-14 | Rangarajan Sampath | Compositions for use in identification of adventitious viruses |
| US8084207B2 (en) | 2005-03-03 | 2011-12-27 | Ibis Bioscience, Inc. | Compositions for use in identification of papillomavirus |
| CN103589650A (zh) | 2005-03-18 | 2014-02-19 | 米克罗比亚公司 | 产油酵母和真菌中类胡萝卜素的产生 |
| JP2006280297A (ja) * | 2005-04-01 | 2006-10-19 | Tosoh Corp | ゲラニルゲラニル2リン酸合成酵素及びその遺伝子等 |
| WO2007014045A2 (en) | 2005-07-21 | 2007-02-01 | Isis Pharmaceuticals, Inc. | Methods for rapid identification and quantitation of nucleic acid variants |
| US20080274520A1 (en) | 2005-09-08 | 2008-11-06 | Bastien Chevreux | Novel Gene Sms 37 |
| CA2627134A1 (en) | 2005-10-28 | 2007-05-03 | Tosoh Corporation | Method of preparing carotenoid synthesizing microorganism and method of producing carotenoids |
| JP5023474B2 (ja) * | 2005-10-28 | 2012-09-12 | 東ソー株式会社 | カロテノイド合成微生物の作製方法およびカロテノイドの製造方法 |
| JP2007151475A (ja) * | 2005-12-06 | 2007-06-21 | Tosoh Corp | 新規微生物およびそれを用いたゼアキサンチンの製造方法 |
| JP4887764B2 (ja) * | 2005-12-06 | 2012-02-29 | 東ソー株式会社 | 新規微生物およびそれを用いたリコペンの製造法 |
| DE102006001868B4 (de) * | 2006-01-13 | 2012-03-01 | Austriamicrosystems Ag | Schaltungsanordnung und Verfahren zur Ansteuerung einer elektrischen Last und eine Energieversorgungseinrichtung |
| US8114645B2 (en) * | 2006-05-19 | 2012-02-14 | The Regents Of The University Of California | Methods for increasing isoprenoid and isoprenoid precursor production by modulating fatty acid levels |
| AU2012202630B2 (en) * | 2006-05-26 | 2014-01-16 | Amyris, Inc. | Production of isoprenoids |
| WO2008008256A2 (en) * | 2006-07-07 | 2008-01-17 | The Regents Of The University Of California | Methods for enhancing production of isoprenoid compounds by host cells |
| EP2064332B1 (en) | 2006-09-14 | 2012-07-18 | Ibis Biosciences, Inc. | Targeted whole genome amplification method for identification of pathogens |
| US8691555B2 (en) | 2006-09-28 | 2014-04-08 | Dsm Ip Assests B.V. | Production of carotenoids in oleaginous yeast and fungi |
| US8871471B2 (en) | 2007-02-23 | 2014-10-28 | Ibis Biosciences, Inc. | Methods for rapid forensic DNA analysis |
| US7531980B2 (en) * | 2007-03-02 | 2009-05-12 | Honeywell International Inc. | Aircraft cabin pressure controls: duty cycle offset to compensate for asymmetric motor loading in an open-loop motor control system |
| US9598724B2 (en) | 2007-06-01 | 2017-03-21 | Ibis Biosciences, Inc. | Methods and compositions for multiple displacement amplification of nucleic acids |
| WO2009005704A1 (en) * | 2007-07-03 | 2009-01-08 | The Regents Of The University Of California | Methods of increasing isoprenoid or isoprenoid precursor production |
| BRPI0823506A8 (pt) | 2007-12-13 | 2018-05-15 | Danisco Us Inc Genencor Div | composições e métodos para a produção de isoprene |
| ES2330602B1 (es) * | 2008-03-19 | 2010-09-30 | Vitatene, S.A | Metodo de produccion de fitoeno y/o fitoflueno, o mezclas de carotenoides con alto contenido en los mismos. |
| JP2011518564A (ja) | 2008-04-23 | 2011-06-30 | ダニスコ・ユーエス・インク | 改良された微生物によるイソプレン産出用のイソプレンシンターゼ変異体 |
| US9909146B2 (en) * | 2008-07-04 | 2018-03-06 | Scientist Of Fortune S.A. | Production of alkenes by enzymatic decarboxylation of 3-hydroxyalkanoic acids |
| US9556456B2 (en) * | 2008-09-09 | 2017-01-31 | Battelle Memorial Institute | Production of bio-based materials using photobioreactors with binary cultures |
| US8148163B2 (en) | 2008-09-16 | 2012-04-03 | Ibis Biosciences, Inc. | Sample processing units, systems, and related methods |
| WO2010033599A2 (en) | 2008-09-16 | 2010-03-25 | Ibis Biosciences, Inc. | Mixing cartridges, mixing stations, and related kits, systems, and methods |
| EP2344893B1 (en) | 2008-09-16 | 2014-10-15 | Ibis Biosciences, Inc. | Microplate handling systems and methods |
| US8158936B2 (en) | 2009-02-12 | 2012-04-17 | Ibis Biosciences, Inc. | Ionization probe assemblies |
| EP2421966A2 (en) | 2009-04-23 | 2012-02-29 | Danisco US Inc. | Three-dimensional structure of isoprene synthase and its use thereof for generating variants |
| WO2011008972A1 (en) | 2009-07-17 | 2011-01-20 | Ibis Biosciences, Inc. | Systems for bioagent identification |
| WO2011008971A1 (en) | 2009-07-17 | 2011-01-20 | Ibis Biosciences, Inc. | Lift and mount apparatus |
| US8034603B2 (en) * | 2009-09-15 | 2011-10-11 | Andrew Ball | Nucleic acid molecule |
| US9890408B2 (en) | 2009-10-15 | 2018-02-13 | Ibis Biosciences, Inc. | Multiple displacement amplification |
| EP2336310A1 (en) | 2009-12-16 | 2011-06-22 | Isobionics B.V. | Valencene synthase |
| AU2009357243B2 (en) | 2009-12-22 | 2014-07-03 | Global Bioenergies | Process for the production of isoprenol from mevalonate employing a diphosphomevalonate decarboxylase |
| BR122021005297B1 (pt) | 2010-06-02 | 2022-02-22 | Evolva, Inc | Método para transferir uma segunda porção de açúcar para uma posição c-2' de uma glicose em um glicosídeo de esteviol |
| PH12013500553A1 (en) | 2010-10-19 | 2013-05-06 | Global Bioenergies | Production of alkenes by combined enzymatic conversion of 3-hydroxyalkanoic acids |
| JP2014502148A (ja) | 2010-10-27 | 2014-01-30 | ダニスコ・ユーエス・インク | イソプレン生産の向上を目的としたイソプレン合成酵素変異体 |
| JP6262653B2 (ja) | 2011-08-08 | 2018-01-17 | エヴォルヴァ エスアー.Evolva Sa. | ステビオール配糖体の組換え生産 |
| US9163263B2 (en) | 2012-05-02 | 2015-10-20 | The Goodyear Tire & Rubber Company | Identification of isoprene synthase variants with improved properties for the production of isoprene |
| WO2014052054A1 (en) * | 2012-09-25 | 2014-04-03 | Albert Einstein College Of Medicine Of Yeshiva University | Enzymatic platform for the synthesis of isoprenoid precursors and uses thereof |
| WO2014089436A1 (en) * | 2012-12-07 | 2014-06-12 | Ginkgo Bioworks, Inc. | Methods and systems for methylotrophic production of organic compounds |
| KR20150115002A (ko) | 2013-02-06 | 2015-10-13 | 에볼바 에스아 | 레바우디오시드 d 및 레바우디오시드 m의 개선된 생산 방법 |
| CN105189771B (zh) | 2013-02-11 | 2019-11-05 | 埃沃尔瓦公司 | 在重组宿主中有效产生甜菊醇糖苷 |
| WO2014151748A1 (en) * | 2013-03-15 | 2014-09-25 | Dsm Ip Assets B.V. | Use of thermophilic nucleases for degrading nucleic acids |
| JP6282813B2 (ja) * | 2013-07-16 | 2018-02-21 | 住友ゴム工業株式会社 | ヒドロキシメチルグルタリルCoAレダクターゼの発現をbZIP型転写因子により調整する方法、bZIP型転写因子をコードする遺伝子が導入されたイソプレノイド産生植物、及び該イソプレノイド産生植物を用いたポリイソプレノイドの製造方法 |
| WO2016008885A1 (en) * | 2014-07-14 | 2016-01-21 | Photanol B.V. | Biosynthesis of sesquiterpenes in cyanobacteria |
| CA2957331A1 (en) | 2014-08-11 | 2016-02-18 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| US10612064B2 (en) | 2014-09-09 | 2020-04-07 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| EP4148137A1 (en) | 2015-01-30 | 2023-03-15 | Evolva SA | Production of steviol glycosides in recombinant hosts |
| CA2979931A1 (en) | 2015-03-16 | 2016-09-22 | Dsm Ip Assets B.V. | Udp-glycosyltransferases |
| BR112018002564A2 (pt) | 2015-08-07 | 2018-09-25 | Evolva Sa | produção de glicosídeos de esteviol em hospedeiros recombinantes |
| US20170145441A1 (en) * | 2015-08-17 | 2017-05-25 | INVISTA North America S.à.r.l. | Methods, hosts, and reagents related thereto for production of unsaturated pentahydrocarbons, derivatives and intermediates thereof |
| WO2017036495A1 (de) * | 2015-08-28 | 2017-03-09 | Phytowelt Greentechnologies Gmbh | Verfahren zur fermentativen alpha-ionen produktion |
| CN109195457A (zh) | 2016-04-13 | 2019-01-11 | 埃沃尔瓦公司 | 在重组宿主中产生甜菊醇糖苷 |
| US10815514B2 (en) | 2016-05-16 | 2020-10-27 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| CN110100006A (zh) | 2016-11-07 | 2019-08-06 | 埃沃尔瓦公司 | 重组宿主中甜菊糖苷的生产 |
| US11634733B2 (en) | 2017-06-30 | 2023-04-25 | Inv Nylon Chemicals Americas, Llc | Methods, materials, synthetic hosts and reagents for the biosynthesis of hydrocarbons and derivatives thereof |
| WO2019006257A1 (en) | 2017-06-30 | 2019-01-03 | Invista North America .S.A.R.L. | METHODS, SYNTHETIC HOSTS AND REAGENTS FOR HYDROCARBON BIOSYNTHESIS |
| US11505809B2 (en) | 2017-09-28 | 2022-11-22 | Inv Nylon Chemicals Americas Llc | Organisms and biosynthetic processes for hydrocarbon synthesis |
| CA3084263A1 (en) | 2017-12-07 | 2019-06-13 | Zymergen Inc. | Engineered biosynthetic pathways for production of (6e)-8-hydroxygeraniol by fermentation |
| CN111868047A (zh) | 2017-12-21 | 2020-10-30 | 齐默尔根公司 | 荆芥内半缩醛氧化还原酶、荆芥内半缩醛合酶和能够产生荆芥内酯的微生物 |
| JP6810096B2 (ja) * | 2018-05-09 | 2021-01-06 | Eneos株式会社 | カロテノイドの製造方法 |
| CN109880745A (zh) * | 2019-03-15 | 2019-06-14 | 江苏大学 | 一种利用腌制废水、晒盐卤水分段培养盐藻的方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3891504A (en) | 1970-07-31 | 1975-06-24 | Hoffmann La Roche | Process for the manufacture of zeaxanthin |
| US5015580A (en) * | 1987-07-29 | 1991-05-14 | Agracetus | Particle-mediated transformation of soybean plants and lines |
| US5328845A (en) * | 1992-03-27 | 1994-07-12 | Universal Foods Corporation | Fungal negative microorganism capable of producing high levels of beta-carotene |
| US5466599A (en) * | 1993-04-19 | 1995-11-14 | Universal Foods Corporation | Astaxanthin over-producing strains of phaffia rhodozyma |
| US5985623A (en) * | 1995-01-24 | 1999-11-16 | Shin-Etsu Bio, Inc. | DNA segments and methods for increasing polysaccharide production |
| DE69631924T2 (de) * | 1995-06-09 | 2004-08-12 | Dsm Ip Assets B.V. | Fermentative Herstellung von Carotenoiden |
| EP0872554B1 (en) | 1996-12-02 | 2003-06-11 | F. Hoffmann-La Roche Ag | Improved fermentative carotenoid production |
| US5935808A (en) * | 1997-07-29 | 1999-08-10 | Yissum Research And Development Company Of The Hebrew University Of Jerusalem | Carotenoid-producing bacterial species and process for production of carotenoids using same |
| US6208893B1 (en) * | 1998-01-27 | 2001-03-27 | Genetronics, Inc. | Electroporation apparatus with connective electrode template |
| KR100657388B1 (ko) * | 1998-04-14 | 2006-12-13 | 교와 학꼬 고교 가부시키가이샤 | 미생물에 의한 이소프레노이드 화합물의 제조 방법 |
| EP1095033A1 (en) | 1998-07-06 | 2001-05-02 | Eastman Chemical Company | Method of producing vitamin e |
| EP2100963B1 (en) * | 1998-07-06 | 2011-12-14 | DCV Inc. doing business as Bio-Technical Resourses | Method of vitamin production |
| ES2156735B1 (es) | 1999-06-09 | 2002-02-16 | Antibioticos Sau | Procedimiento de produccion de licopeno. |
| US6133785A (en) | 1999-06-30 | 2000-10-17 | Harris Corporation | False carrier lock receiver and associated methods for detection |
-
2002
- 2002-06-05 AU AU2002316966A patent/AU2002316966B2/en not_active Ceased
- 2002-06-05 EP EP02745362A patent/EP1392824B1/en not_active Expired - Lifetime
- 2002-06-05 US US10/166,225 patent/US6989257B2/en not_active Expired - Lifetime
- 2002-06-05 JP JP2003502205A patent/JP4280627B2/ja not_active Expired - Fee Related
- 2002-06-05 ES ES02745362T patent/ES2311613T3/es not_active Expired - Lifetime
- 2002-06-05 KR KR1020037015938A patent/KR100704072B1/ko not_active Expired - Fee Related
- 2002-06-05 CA CA002449885A patent/CA2449885A1/en not_active Abandoned
- 2002-06-05 AT AT02745362T patent/ATE405638T1/de not_active IP Right Cessation
- 2002-06-05 DE DE60228439T patent/DE60228439D1/de not_active Expired - Lifetime
- 2002-06-05 WO PCT/EP2002/006171 patent/WO2002099095A2/en not_active Ceased
- 2002-06-05 CN CNA028113802A patent/CN1630718A/zh active Pending
-
2005
- 2005-05-13 US US11/129,143 patent/US7232679B2/en not_active Expired - Lifetime
Cited By (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101484584B (zh) * | 2006-05-26 | 2013-03-27 | 阿米瑞斯公司 | 类异戊二烯的生产 |
| US9200296B2 (en) | 2006-05-26 | 2015-12-01 | Amyris Inc. | Production of isoprenoids |
| CN105331518A (zh) * | 2006-05-26 | 2016-02-17 | 阿迈瑞斯公司 | 制造生物有机化合物的设备 |
| US10106822B2 (en) | 2006-05-26 | 2018-10-23 | Amyris, Inc. | Production of isoprenoids |
| CN102492701B (zh) * | 2007-06-21 | 2013-11-06 | 日立造船株式会社 | 编码杜仲的甲羟戊酸途径的酶的基因 |
| CN102492701A (zh) * | 2007-06-21 | 2012-06-13 | 日立造船株式会社 | 编码杜仲的甲羟戊酸途径的酶的基因 |
| CN111304260A (zh) * | 2012-06-01 | 2020-06-19 | 朗泽科技新西兰有限公司 | 重组代谢微生物及其用途 |
| US12286660B2 (en) | 2012-06-01 | 2025-04-29 | Lanzatech, Inc. | Microbial fermentation for the production of terpenes |
| CN105339490A (zh) * | 2012-12-20 | 2016-02-17 | 帝斯曼知识产权资产管理有限公司 | 乙酰转移酶及其用于产生类胡萝卜素的用途 |
| CN109715796B (zh) * | 2016-03-31 | 2021-04-09 | Jxtg能源株式会社 | 类胡萝卜素的制造方法 |
| CN109715796A (zh) * | 2016-03-31 | 2019-05-03 | Jxtg能源株式会社 | 类胡萝卜素的制造方法 |
| CN108285902A (zh) * | 2017-11-03 | 2018-07-17 | 杭州爱蔻思生物科技有限公司 | 生产高价值天然产物的工程菌的构造方法 |
| CN109666683A (zh) * | 2019-02-27 | 2019-04-23 | 昆明理工大学 | 乙酰辅酶A乙酰转移酶基因RKAcaT2及其应用 |
| CN109666683B (zh) * | 2019-02-27 | 2021-10-29 | 昆明理工大学 | 乙酰辅酶A乙酰转移酶基因RKAcaT2及其应用 |
| CN109777815A (zh) * | 2019-03-28 | 2019-05-21 | 昆明理工大学 | HMG-CoA合成酶基因RKHMGCS及其应用 |
| CN115003823A (zh) * | 2019-12-26 | 2022-09-02 | 加利福尼亚大学董事会 | 用于生产大麻素和其他异戊二烯化化合物的生物合成平台 |
| CN115605589A (zh) * | 2020-05-15 | 2023-01-13 | 巴斯夫欧洲公司(De) | 改进的用于生产类异戊二烯的方法 |
| CN117965414A (zh) * | 2024-04-01 | 2024-05-03 | 北京微构工场生物技术有限公司 | 一种重组盐单胞菌及其在生产异戊二烯中的应用 |
| CN117965414B (zh) * | 2024-04-01 | 2024-06-14 | 北京微构工场生物技术有限公司 | 一种重组盐单胞菌及其在生产异戊二烯中的应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2311613T3 (es) | 2009-02-16 |
| AU2002316966B2 (en) | 2007-05-17 |
| EP1392824A2 (en) | 2004-03-03 |
| JP4280627B2 (ja) | 2009-06-17 |
| CA2449885A1 (en) | 2002-12-12 |
| US20030148416A1 (en) | 2003-08-07 |
| US7232679B2 (en) | 2007-06-19 |
| WO2002099095A3 (en) | 2003-12-18 |
| ATE405638T1 (de) | 2008-09-15 |
| US6989257B2 (en) | 2006-01-24 |
| KR100704072B1 (ko) | 2007-04-05 |
| KR20040010683A (ko) | 2004-01-31 |
| WO2002099095A2 (en) | 2002-12-12 |
| EP1392824B1 (en) | 2008-08-20 |
| DE60228439D1 (de) | 2008-10-02 |
| US20050266518A1 (en) | 2005-12-01 |
| JP2004527265A (ja) | 2004-09-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1630718A (zh) | 改进的类异戊二烯生产 | |
| JP6898365B2 (ja) | 組換え微生物およびその使用方法 | |
| CN1262648C (zh) | 改进的类异戊二烯的生产 | |
| EP3230459B1 (en) | Recombinant microorganisms exhibiting increased flux through a fermentation pathway | |
| US10000749B2 (en) | Valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof | |
| CN1227362C (zh) | 生产刺糖噻杀虫剂所用的生物合成基因 | |
| CN101044243A (zh) | 类异戊二烯的生产方法 | |
| CN111849794B (zh) | 一种酿酒酵母重组菌及其构建方法和应用 | |
| CN101080490A (zh) | 改进的甲羟戊酸激酶 | |
| CN1993377A (zh) | 丙氨酸2,3氨基变位酶 | |
| CN116113699B (zh) | 改造的磷酸烯醇丙酮酸羧化酶及其在提高谷氨酸棒杆菌氨基酸产量中的应用 | |
| CN1266101A (zh) | 虾青素合成酶 | |
| CN1813065A (zh) | 反馈抗性乙酰羟酸合成酶突变体 | |
| WO2021050371A1 (en) | Biotin synthases for efficient production of biotin | |
| EP2141236A1 (en) | Process for production of lipstatin and microorganisms therefore | |
| JP2022116107A (ja) | スクアレン消費酵素のスクリーニング方法及びスクアレン-ホペン環化酵素 | |
| CN109072216B (zh) | 变异型四异戊烯基-β-姜黄烯环化酶及龙涎香醇的制备方法 | |
| CN1387566A (zh) | 环状缩肽合成酶及其基因、以及环状缩肽的大规模生产系统 | |
| CN1498270A (zh) | 基因已被破坏的酵母 | |
| CN1230544C (zh) | 磷酸己酮糖异构酶和编码该酶的基因 | |
| CN1906291A (zh) | 用扩增zwf基因制备L-氨基酸的方法 | |
| WO2014102180A1 (en) | Propanol production by lactobacillus bacterial hosts | |
| CN117210429A (zh) | 一种组氨酸三甲基化酶EgtD突变体及其应用 | |
| CN114410599A (zh) | 羰基还原酶突变体及其制备瑞舒伐他汀手性中间体的应用 | |
| CN1377407A (zh) | 生产被官能团修饰的次级代谢产物的转化体和新的生物合成基因 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20050622 |